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    Structured Review

    ATCC mbc mic50 mic90 mic range mbc range mpall
    Mbc Mic50 Mic90 Mic Range Mbc Range Mpall, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 711 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mic90+range/Auricularia+fuscosuccinea+(Montagne)+Farlow%2C+teleomorph/pm37570659-88-16-7
    Average 96 stars, based on 711 article reviews
    mbc mic50 mic90 mic range mbc range mpall - by Bioz Stars, 2026-10
    96/100 stars

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    In Vitro:

    Article Title: Efficacy and Safety of PL-5 (Peceleganan) Spray for Wound Infections
    Article Snippet: Antibacterial effect of antimicrobial peptide PL-5 and imipenem cilastatin sodium on Escherichia coli in vitro Sample Bacteria Strains NO. of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MIC range (μg/ml) MIC50 (μg/ml) MIC90 (μg/ml) MIC Geometric mean (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 1/8 solvent Culture medium PL-5 ESBLs E. Coli (ATCC 35218) 1 1 1 1 1 1 0 0 0 - - 0 1 4 4 4 4 Non-ESBLs E. Coli ( ATCC 25922) 1 1 1 1 1 1 0 0 0 - - 0 1 4 4 4 4 ESBLs E. Coli 79 74 73 71 70 61 23 0 0 - - 0 79 2~>64 4 32 4.68 Non-ESBLs E. Coli 40 37 33 33 33 18 2 0 0 - - 0 40 2~>64 8 64 8.14 imipenem cilastatin sodium ESBLs E. Coli (ATCC 35218) 1 - - 1 1 1 1 1 1 1 0 0 1 0.25 0.25 0.25 0.25 Non-ESBLs E. Coli (ATCC 25922) 1 - 1 1 1 1 1 1 1 1 0 0 1 0.25 0.25 0.25 0.25 ESBLs E. Coli 79 - 77 77 73 73 61 54 47 30 2 0 79 <0.125~>32 0.5 4 0.84 Non-ESBLs E. Coli 40 - 40 40 40 40 40 39 33 21 0 0 40 0.25~2 0.25 1 0.39 Bactericidal effect of antimicrobial peptide PL-5 and imipenem cilastatin sodium on Escherichia coli in vitro Sample Bacteria Strains Number of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MBC range (μg/ml) MBC50 (μg/ml) MBC90 (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 1/8 Solvent Culture medium PL-5 ESBLs E. Coli (ATCC 35218) 1 1 1 1 1 1 0 0 0 - 0 0 1 4 4 4 Non-ESBLs E. Coli (ATCC 25922) 1 1 1 1 1 1 0 0 0 - 0 0 1 4 4 4 ESBLs E. Coli 79 74 70 62 50 40 13 0 0 - 0 0 79 2~>64 4 64 Non-ESBLs E. Coli 40 35 32 30 25 10 1 0 0 - 0 0 40 2~>64 8 >64 imipenem cilastatin sodium ESBLs E. Coli (ATCC 35218) 1 - - 1 1 0 0 0 0 0 0 0 1 8 8 8 Non-ESBLs E. Coli (ATCC 25922) 1 - - 94 81 1 1 1 1 0 0 0 1 0.5 0.5 0.5 ESBLs E. Coloi 79 - - 94 81 61 46 37 23 12 1 0 79 <0.125~>16 2 >16 Non-ESBLs E. Coli 40 - - 89 77 12 12 8 3 1 0 0 40 0.25~>16 16 >16 Cumulative antibacterial percentage of antimicrobial peptide PL-5 and imipenem cilastatin sodium on .. Antibacterial effect of antimicrobial peptide PL-5 and imipenem cilastatin sodium on Escherichia coli in vitro Sample Bacteria Strains NO. of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MIC range (μg/ml) MIC50 (μg/ml) MIC90 (μg/ml) MIC Geometric mean (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 1/8 solvent Culture medium PL-5 ESBLs E. Coli (ATCC 35218) 1 1 1 1 1 1 0 0 0 - - 0 1 4 4 4 4 Non-ESBLs E. Coli ( ATCC 25922) 1 1 1 1 1 1 0 0 0 - - 0 1 4 4 4 4 ESBLs E. Coli 79 74 73 71 70 61 23 0 0 - - 0 79 2~>64 4 32 4.68 Non-ESBLs E. Coli 40 37 33 33 33 18 2 0 0 - - 0 40 2~>64 8 64 8.14 imipenem cilastatin sodium ESBLs E. Coli (ATCC 35218) 1 - - 1 1 1 1 1 1 1 0 0 1 0.25 0.25 0.25 0.25 Non-ESBLs E. Coli (ATCC 25922) 1 - 1 1 1 1 1 1 1 1 0 0 1 0.25 0.25 0.25 0.25 ESBLs E. Coli 79 - 77 77 73 73 61 54 47 30 2 0 79 <0.125~>32 0.5 4 0.84 Non-ESBLs E. Coli 40 - 40 40 40 40 40 39 33 21 0 0 40 0.25~2 0.25 1 0.39 Bactericidal effect of antimicrobial peptide PL-5 and imipenem cilastatin sodium on Escherichia coli in vitro Sample Bacteria Strains Number of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MBC range (μg/ml) MBC50 (μg/ml) MBC90 (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 1/8 Solvent Culture medium PL-5 ESBLs E. Coli (ATCC 35218) 1 1 1 1 1 1 0 0 0 - 0 0 1 4 4 4 Non-ESBLs E. Coli (ATCC 25922) 1 1 1 1 1 1 0 0 0 - 0 0 1 4 4 4 ESBLs E. Coli 79 74 70 62 50 40 13 0 0 - 0 0 79 2~>64 4 64 Non-ESBLs E. Coli 40 35 32 30 25 10 1 0 0 - 0 0 40 2~>64 8 >64 imipenem cilastatin sodium ESBLs E. Coli (ATCC 35218) 1 - - 1 1 0 0 0 0 0 0 0 1 8 8 8 Non-ESBLs E. Coli (ATCC 25922) 1 - - 94 81 1 1 1 1 0 0 0 1 0.5 0.5 0.5 ESBLs E. Coloi 79 - - 94 81 61 46 37 23 12 1 0 79 <0.125~>16 2 >16 Non-ESBLs E. Coli 40 - - 89 77 12 12 8 3 1 0 0 40 0.25~>16 16 >16 Cumulative antibacterial percentage of antimicrobial peptide PL-5 and imipenem cilastatin sodium on ..

    Article Title: Efficacy and Safety of PL-5 (Peceleganan) Spray for Wound Infections
    Article Snippet: .. Antibacterial effect of antimicrobial peptide PL-5 and vancomycin on Enterococcus faecalis and Enterococcus faecium in vitro Sample Bacteria Strains Number of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MIC range (μg/ml) MIC50 (μg/ml) MIC90 (μg/ml) MIC Geometric mean (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 solvent Culture medium PL-5 Enterococcus faecalis (ATCC 29212) 1 1 1 0 0 0 0 0 0 - 0 1 32 32 32 32 Enterococcus faecalis 40 32 26 22 19 17 3 0 0 - 0 40 2~>64 16 >64 14.17 Enterococcus faecium 40 37 29 25 22 21 3 0 0 - 0 40 2~>64 4 64 11.31 Vancomycin Enterococcus faecalis (ATCC 29212) 1 - 1 1 1 1 1 1 0 0 0 1 1 1 1 1 Enterococcus faecalis 40 - 40 40 40 40 40 39 23 0 0 40 0.5~2 0.5 1 0.68 Enterococcus faecium 40 - 32 32 32 32 32 26 15 0 0 40 0.5 ~ 32 1 >32 1.71 Bactericidal effect of antimicrobial peptide PL-5 and vancomycin on Enterococcus faecalis and Enterococcus faecium in vitro Sample Bacteria Strains Number of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MBC range (μg/ml) MBC50 (μg/ml) MBC90 (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 solvent Culture medium PL-5 Enterococcus faecalis (ATCC 29212) 1 1 1 0 0 0 0 0 0 - 0 1 32 32 32 Enterococcus faecalis 40 31 25 22 16 4 1 0 0 - 0 40 2~>64 16 >64 Enterococcus faecium 40 34 27 22 19 10 1 0 0 - 0 40 2~>64 16 >64 Vancomycin Enterococcus faecalis (ATCC 29212) 1 - 0 0 0 0 0 0 0 0 0 1 >32 >32 >32 Enterococcus faecalis 40 - 33 10 3 0 0 0 0 0 0 40 8~>32 32 >32 Enterococcus faecium 40 - 20 4 0 0 0 0 0 0 0 40 16~>32 32 >32 Cumulative antibacterial percentage of antimicrobial peptide PL-5 and vancomycin on Enterococcus faecalis and Enterococcus faecium in vitro Sample Bacteria Strains Number of Strains Cumulative antibacterial percentage of different concentrations (μg/ml) of tested drugs (%) MBC50/MIC50 MBC90/MIC90 64 32 16 8 4 2 1 0.5 0.25 PL-5 Enterococcus faecalis 40 80 65 55 48 43 8 0 0 - 1 - Enterococcus faecium 40 93 73 63 55 53 8 0 0 - 4 >1 Vancomycin Enterococcus faecalis 40 - 100 100 100 100 100 98 58 0 64 >32 Enterococcus faecium 40 - 80 80 80 80 80 65 38 0 32 - Cumulative bactericidal percentage of antimicrobial peptide PL-5 and vancomycin on Enterococcus faecalis and Enterococcus faecium in vitro Sample Bacteria Strains Number of Strains Cumulative bactericidal percentage of different concentrations (μg/ml) of tested drugs (%) 64 32 16 8 4 2 1 0.5 0.25 PL-5 Enterococcus faecalis 40 78 63 55 40 14 10 3 0 - Enterococcus faecium 40 85 68 55 48 25 25 3 0 - Vancomycin Enterococcus faecalis 40 - 83 25 8 100 0 0 0 0 Enterococcus faecium 40 - 50 10 0 55 0 0 0 0 4. ..

    Bacteria:

    Article Title: Efficacy and Safety of PL-5 (Peceleganan) Spray for Wound Infections
    Article Snippet: Antibacterial effect of antimicrobial peptide PL-5 and imipenem cilastatin sodium on Escherichia coli in vitro Sample Bacteria Strains NO. of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MIC range (μg/ml) MIC50 (μg/ml) MIC90 (μg/ml) MIC Geometric mean (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 1/8 solvent Culture medium PL-5 ESBLs E. Coli (ATCC 35218) 1 1 1 1 1 1 0 0 0 - - 0 1 4 4 4 4 Non-ESBLs E. Coli ( ATCC 25922) 1 1 1 1 1 1 0 0 0 - - 0 1 4 4 4 4 ESBLs E. Coli 79 74 73 71 70 61 23 0 0 - - 0 79 2~>64 4 32 4.68 Non-ESBLs E. Coli 40 37 33 33 33 18 2 0 0 - - 0 40 2~>64 8 64 8.14 imipenem cilastatin sodium ESBLs E. Coli (ATCC 35218) 1 - - 1 1 1 1 1 1 1 0 0 1 0.25 0.25 0.25 0.25 Non-ESBLs E. Coli (ATCC 25922) 1 - 1 1 1 1 1 1 1 1 0 0 1 0.25 0.25 0.25 0.25 ESBLs E. Coli 79 - 77 77 73 73 61 54 47 30 2 0 79 <0.125~>32 0.5 4 0.84 Non-ESBLs E. Coli 40 - 40 40 40 40 40 39 33 21 0 0 40 0.25~2 0.25 1 0.39 Bactericidal effect of antimicrobial peptide PL-5 and imipenem cilastatin sodium on Escherichia coli in vitro Sample Bacteria Strains Number of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MBC range (μg/ml) MBC50 (μg/ml) MBC90 (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 1/8 Solvent Culture medium PL-5 ESBLs E. Coli (ATCC 35218) 1 1 1 1 1 1 0 0 0 - 0 0 1 4 4 4 Non-ESBLs E. Coli (ATCC 25922) 1 1 1 1 1 1 0 0 0 - 0 0 1 4 4 4 ESBLs E. Coli 79 74 70 62 50 40 13 0 0 - 0 0 79 2~>64 4 64 Non-ESBLs E. Coli 40 35 32 30 25 10 1 0 0 - 0 0 40 2~>64 8 >64 imipenem cilastatin sodium ESBLs E. Coli (ATCC 35218) 1 - - 1 1 0 0 0 0 0 0 0 1 8 8 8 Non-ESBLs E. Coli (ATCC 25922) 1 - - 94 81 1 1 1 1 0 0 0 1 0.5 0.5 0.5 ESBLs E. Coloi 79 - - 94 81 61 46 37 23 12 1 0 79 <0.125~>16 2 >16 Non-ESBLs E. Coli 40 - - 89 77 12 12 8 3 1 0 0 40 0.25~>16 16 >16 Cumulative antibacterial percentage of antimicrobial peptide PL-5 and imipenem cilastatin sodium on .. Antibacterial effect of antimicrobial peptide PL-5 and imipenem cilastatin sodium on Escherichia coli in vitro Sample Bacteria Strains NO. of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MIC range (μg/ml) MIC50 (μg/ml) MIC90 (μg/ml) MIC Geometric mean (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 1/8 solvent Culture medium PL-5 ESBLs E. Coli (ATCC 35218) 1 1 1 1 1 1 0 0 0 - - 0 1 4 4 4 4 Non-ESBLs E. Coli ( ATCC 25922) 1 1 1 1 1 1 0 0 0 - - 0 1 4 4 4 4 ESBLs E. Coli 79 74 73 71 70 61 23 0 0 - - 0 79 2~>64 4 32 4.68 Non-ESBLs E. Coli 40 37 33 33 33 18 2 0 0 - - 0 40 2~>64 8 64 8.14 imipenem cilastatin sodium ESBLs E. Coli (ATCC 35218) 1 - - 1 1 1 1 1 1 1 0 0 1 0.25 0.25 0.25 0.25 Non-ESBLs E. Coli (ATCC 25922) 1 - 1 1 1 1 1 1 1 1 0 0 1 0.25 0.25 0.25 0.25 ESBLs E. Coli 79 - 77 77 73 73 61 54 47 30 2 0 79 <0.125~>32 0.5 4 0.84 Non-ESBLs E. Coli 40 - 40 40 40 40 40 39 33 21 0 0 40 0.25~2 0.25 1 0.39 Bactericidal effect of antimicrobial peptide PL-5 and imipenem cilastatin sodium on Escherichia coli in vitro Sample Bacteria Strains Number of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MBC range (μg/ml) MBC50 (μg/ml) MBC90 (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 1/8 Solvent Culture medium PL-5 ESBLs E. Coli (ATCC 35218) 1 1 1 1 1 1 0 0 0 - 0 0 1 4 4 4 Non-ESBLs E. Coli (ATCC 25922) 1 1 1 1 1 1 0 0 0 - 0 0 1 4 4 4 ESBLs E. Coli 79 74 70 62 50 40 13 0 0 - 0 0 79 2~>64 4 64 Non-ESBLs E. Coli 40 35 32 30 25 10 1 0 0 - 0 0 40 2~>64 8 >64 imipenem cilastatin sodium ESBLs E. Coli (ATCC 35218) 1 - - 1 1 0 0 0 0 0 0 0 1 8 8 8 Non-ESBLs E. Coli (ATCC 25922) 1 - - 94 81 1 1 1 1 0 0 0 1 0.5 0.5 0.5 ESBLs E. Coloi 79 - - 94 81 61 46 37 23 12 1 0 79 <0.125~>16 2 >16 Non-ESBLs E. Coli 40 - - 89 77 12 12 8 3 1 0 0 40 0.25~>16 16 >16 Cumulative antibacterial percentage of antimicrobial peptide PL-5 and imipenem cilastatin sodium on ..

    Article Title: Efficacy and Safety of PL-5 (Peceleganan) Spray for Wound Infections
    Article Snippet: .. Antibacterial effect of antimicrobial peptide PL-5 and vancomycin on Enterococcus faecalis and Enterococcus faecium in vitro Sample Bacteria Strains Number of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MIC range (μg/ml) MIC50 (μg/ml) MIC90 (μg/ml) MIC Geometric mean (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 solvent Culture medium PL-5 Enterococcus faecalis (ATCC 29212) 1 1 1 0 0 0 0 0 0 - 0 1 32 32 32 32 Enterococcus faecalis 40 32 26 22 19 17 3 0 0 - 0 40 2~>64 16 >64 14.17 Enterococcus faecium 40 37 29 25 22 21 3 0 0 - 0 40 2~>64 4 64 11.31 Vancomycin Enterococcus faecalis (ATCC 29212) 1 - 1 1 1 1 1 1 0 0 0 1 1 1 1 1 Enterococcus faecalis 40 - 40 40 40 40 40 39 23 0 0 40 0.5~2 0.5 1 0.68 Enterococcus faecium 40 - 32 32 32 32 32 26 15 0 0 40 0.5 ~ 32 1 >32 1.71 Bactericidal effect of antimicrobial peptide PL-5 and vancomycin on Enterococcus faecalis and Enterococcus faecium in vitro Sample Bacteria Strains Number of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MBC range (μg/ml) MBC50 (μg/ml) MBC90 (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 solvent Culture medium PL-5 Enterococcus faecalis (ATCC 29212) 1 1 1 0 0 0 0 0 0 - 0 1 32 32 32 Enterococcus faecalis 40 31 25 22 16 4 1 0 0 - 0 40 2~>64 16 >64 Enterococcus faecium 40 34 27 22 19 10 1 0 0 - 0 40 2~>64 16 >64 Vancomycin Enterococcus faecalis (ATCC 29212) 1 - 0 0 0 0 0 0 0 0 0 1 >32 >32 >32 Enterococcus faecalis 40 - 33 10 3 0 0 0 0 0 0 40 8~>32 32 >32 Enterococcus faecium 40 - 20 4 0 0 0 0 0 0 0 40 16~>32 32 >32 Cumulative antibacterial percentage of antimicrobial peptide PL-5 and vancomycin on Enterococcus faecalis and Enterococcus faecium in vitro Sample Bacteria Strains Number of Strains Cumulative antibacterial percentage of different concentrations (μg/ml) of tested drugs (%) MBC50/MIC50 MBC90/MIC90 64 32 16 8 4 2 1 0.5 0.25 PL-5 Enterococcus faecalis 40 80 65 55 48 43 8 0 0 - 1 - Enterococcus faecium 40 93 73 63 55 53 8 0 0 - 4 >1 Vancomycin Enterococcus faecalis 40 - 100 100 100 100 100 98 58 0 64 >32 Enterococcus faecium 40 - 80 80 80 80 80 65 38 0 32 - Cumulative bactericidal percentage of antimicrobial peptide PL-5 and vancomycin on Enterococcus faecalis and Enterococcus faecium in vitro Sample Bacteria Strains Number of Strains Cumulative bactericidal percentage of different concentrations (μg/ml) of tested drugs (%) 64 32 16 8 4 2 1 0.5 0.25 PL-5 Enterococcus faecalis 40 78 63 55 40 14 10 3 0 - Enterococcus faecium 40 85 68 55 48 25 25 3 0 - Vancomycin Enterococcus faecalis 40 - 83 25 8 100 0 0 0 0 Enterococcus faecium 40 - 50 10 0 55 0 0 0 0 4. ..

    Solvent:

    Article Title: Efficacy and Safety of PL-5 (Peceleganan) Spray for Wound Infections
    Article Snippet: Antibacterial effect of antimicrobial peptide PL-5 and imipenem cilastatin sodium on Escherichia coli in vitro Sample Bacteria Strains NO. of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MIC range (μg/ml) MIC50 (μg/ml) MIC90 (μg/ml) MIC Geometric mean (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 1/8 solvent Culture medium PL-5 ESBLs E. Coli (ATCC 35218) 1 1 1 1 1 1 0 0 0 - - 0 1 4 4 4 4 Non-ESBLs E. Coli ( ATCC 25922) 1 1 1 1 1 1 0 0 0 - - 0 1 4 4 4 4 ESBLs E. Coli 79 74 73 71 70 61 23 0 0 - - 0 79 2~>64 4 32 4.68 Non-ESBLs E. Coli 40 37 33 33 33 18 2 0 0 - - 0 40 2~>64 8 64 8.14 imipenem cilastatin sodium ESBLs E. Coli (ATCC 35218) 1 - - 1 1 1 1 1 1 1 0 0 1 0.25 0.25 0.25 0.25 Non-ESBLs E. Coli (ATCC 25922) 1 - 1 1 1 1 1 1 1 1 0 0 1 0.25 0.25 0.25 0.25 ESBLs E. Coli 79 - 77 77 73 73 61 54 47 30 2 0 79 <0.125~>32 0.5 4 0.84 Non-ESBLs E. Coli 40 - 40 40 40 40 40 39 33 21 0 0 40 0.25~2 0.25 1 0.39 Bactericidal effect of antimicrobial peptide PL-5 and imipenem cilastatin sodium on Escherichia coli in vitro Sample Bacteria Strains Number of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MBC range (μg/ml) MBC50 (μg/ml) MBC90 (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 1/8 Solvent Culture medium PL-5 ESBLs E. Coli (ATCC 35218) 1 1 1 1 1 1 0 0 0 - 0 0 1 4 4 4 Non-ESBLs E. Coli (ATCC 25922) 1 1 1 1 1 1 0 0 0 - 0 0 1 4 4 4 ESBLs E. Coli 79 74 70 62 50 40 13 0 0 - 0 0 79 2~>64 4 64 Non-ESBLs E. Coli 40 35 32 30 25 10 1 0 0 - 0 0 40 2~>64 8 >64 imipenem cilastatin sodium ESBLs E. Coli (ATCC 35218) 1 - - 1 1 0 0 0 0 0 0 0 1 8 8 8 Non-ESBLs E. Coli (ATCC 25922) 1 - - 94 81 1 1 1 1 0 0 0 1 0.5 0.5 0.5 ESBLs E. Coloi 79 - - 94 81 61 46 37 23 12 1 0 79 <0.125~>16 2 >16 Non-ESBLs E. Coli 40 - - 89 77 12 12 8 3 1 0 0 40 0.25~>16 16 >16 Cumulative antibacterial percentage of antimicrobial peptide PL-5 and imipenem cilastatin sodium on .. Antibacterial effect of antimicrobial peptide PL-5 and imipenem cilastatin sodium on Escherichia coli in vitro Sample Bacteria Strains NO. of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MIC range (μg/ml) MIC50 (μg/ml) MIC90 (μg/ml) MIC Geometric mean (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 1/8 solvent Culture medium PL-5 ESBLs E. Coli (ATCC 35218) 1 1 1 1 1 1 0 0 0 - - 0 1 4 4 4 4 Non-ESBLs E. Coli ( ATCC 25922) 1 1 1 1 1 1 0 0 0 - - 0 1 4 4 4 4 ESBLs E. Coli 79 74 73 71 70 61 23 0 0 - - 0 79 2~>64 4 32 4.68 Non-ESBLs E. Coli 40 37 33 33 33 18 2 0 0 - - 0 40 2~>64 8 64 8.14 imipenem cilastatin sodium ESBLs E. Coli (ATCC 35218) 1 - - 1 1 1 1 1 1 1 0 0 1 0.25 0.25 0.25 0.25 Non-ESBLs E. Coli (ATCC 25922) 1 - 1 1 1 1 1 1 1 1 0 0 1 0.25 0.25 0.25 0.25 ESBLs E. Coli 79 - 77 77 73 73 61 54 47 30 2 0 79 <0.125~>32 0.5 4 0.84 Non-ESBLs E. Coli 40 - 40 40 40 40 40 39 33 21 0 0 40 0.25~2 0.25 1 0.39 Bactericidal effect of antimicrobial peptide PL-5 and imipenem cilastatin sodium on Escherichia coli in vitro Sample Bacteria Strains Number of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MBC range (μg/ml) MBC50 (μg/ml) MBC90 (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 1/8 Solvent Culture medium PL-5 ESBLs E. Coli (ATCC 35218) 1 1 1 1 1 1 0 0 0 - 0 0 1 4 4 4 Non-ESBLs E. Coli (ATCC 25922) 1 1 1 1 1 1 0 0 0 - 0 0 1 4 4 4 ESBLs E. Coli 79 74 70 62 50 40 13 0 0 - 0 0 79 2~>64 4 64 Non-ESBLs E. Coli 40 35 32 30 25 10 1 0 0 - 0 0 40 2~>64 8 >64 imipenem cilastatin sodium ESBLs E. Coli (ATCC 35218) 1 - - 1 1 0 0 0 0 0 0 0 1 8 8 8 Non-ESBLs E. Coli (ATCC 25922) 1 - - 94 81 1 1 1 1 0 0 0 1 0.5 0.5 0.5 ESBLs E. Coloi 79 - - 94 81 61 46 37 23 12 1 0 79 <0.125~>16 2 >16 Non-ESBLs E. Coli 40 - - 89 77 12 12 8 3 1 0 0 40 0.25~>16 16 >16 Cumulative antibacterial percentage of antimicrobial peptide PL-5 and imipenem cilastatin sodium on ..

    Article Title: Efficacy and Safety of PL-5 (Peceleganan) Spray for Wound Infections
    Article Snippet: .. Antibacterial effect of antimicrobial peptide PL-5 and vancomycin on Enterococcus faecalis and Enterococcus faecium in vitro Sample Bacteria Strains Number of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MIC range (μg/ml) MIC50 (μg/ml) MIC90 (μg/ml) MIC Geometric mean (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 solvent Culture medium PL-5 Enterococcus faecalis (ATCC 29212) 1 1 1 0 0 0 0 0 0 - 0 1 32 32 32 32 Enterococcus faecalis 40 32 26 22 19 17 3 0 0 - 0 40 2~>64 16 >64 14.17 Enterococcus faecium 40 37 29 25 22 21 3 0 0 - 0 40 2~>64 4 64 11.31 Vancomycin Enterococcus faecalis (ATCC 29212) 1 - 1 1 1 1 1 1 0 0 0 1 1 1 1 1 Enterococcus faecalis 40 - 40 40 40 40 40 39 23 0 0 40 0.5~2 0.5 1 0.68 Enterococcus faecium 40 - 32 32 32 32 32 26 15 0 0 40 0.5 ~ 32 1 >32 1.71 Bactericidal effect of antimicrobial peptide PL-5 and vancomycin on Enterococcus faecalis and Enterococcus faecium in vitro Sample Bacteria Strains Number of Strains Strains of bacteria not growing under different drug concentrations (μg/ml) MBC range (μg/ml) MBC50 (μg/ml) MBC90 (μg/ml) 64 32 16 8 4 2 1 1/2 1/4 solvent Culture medium PL-5 Enterococcus faecalis (ATCC 29212) 1 1 1 0 0 0 0 0 0 - 0 1 32 32 32 Enterococcus faecalis 40 31 25 22 16 4 1 0 0 - 0 40 2~>64 16 >64 Enterococcus faecium 40 34 27 22 19 10 1 0 0 - 0 40 2~>64 16 >64 Vancomycin Enterococcus faecalis (ATCC 29212) 1 - 0 0 0 0 0 0 0 0 0 1 >32 >32 >32 Enterococcus faecalis 40 - 33 10 3 0 0 0 0 0 0 40 8~>32 32 >32 Enterococcus faecium 40 - 20 4 0 0 0 0 0 0 0 40 16~>32 32 >32 Cumulative antibacterial percentage of antimicrobial peptide PL-5 and vancomycin on Enterococcus faecalis and Enterococcus faecium in vitro Sample Bacteria Strains Number of Strains Cumulative antibacterial percentage of different concentrations (μg/ml) of tested drugs (%) MBC50/MIC50 MBC90/MIC90 64 32 16 8 4 2 1 0.5 0.25 PL-5 Enterococcus faecalis 40 80 65 55 48 43 8 0 0 - 1 - Enterococcus faecium 40 93 73 63 55 53 8 0 0 - 4 >1 Vancomycin Enterococcus faecalis 40 - 100 100 100 100 100 98 58 0 64 >32 Enterococcus faecium 40 - 80 80 80 80 80 65 38 0 32 - Cumulative bactericidal percentage of antimicrobial peptide PL-5 and vancomycin on Enterococcus faecalis and Enterococcus faecium in vitro Sample Bacteria Strains Number of Strains Cumulative bactericidal percentage of different concentrations (μg/ml) of tested drugs (%) 64 32 16 8 4 2 1 0.5 0.25 PL-5 Enterococcus faecalis 40 78 63 55 40 14 10 3 0 - Enterococcus faecium 40 85 68 55 48 25 25 3 0 - Vancomycin Enterococcus faecalis 40 - 83 25 8 100 0 0 0 0 Enterococcus faecium 40 - 50 10 0 55 0 0 0 0 4. ..

    Concentration Assay:

    Article Title: Composition and Anti- Helicobacter pylori Properties of Essential Oils Obtained from Selected Mentha Cultivars.
    Article Snippet: .. Mint EOs and Reference Compounds Helicobacter pylori ATCC 43504 Clinical Helicobacter pylori Strains mg/L MIC * MBC MIC50 MIC90 MIC Range MBC Range MpAlL 15.6 15.6 125 125 62.5–250 15.6–250 MpGrL 31.3 31.3 125 250 62.5–250 31.3–250 MpGrF 31.3 125 250 250 125–500 31.3–500 MpMmL 31.3 31.3 62.5 125 62.5–250 31.3–250 MpMmF 31.3 31.3 250 500 250–500 31.3–1000 MpSwL 15.6 62.5 31.3 125 31.3–125 31.3–125 MpSwF 15.6 62.5 250 500 125–500 62.5–500 MsMoL 31.3 31.3 62.5 62.5 31.3–125 31.3–125 MsMoF 15.6 15.6 62.5 62.5 31.3–125 15.6–125 Menthol 62.5 250 7.8 31.3 7.8–31.3 7.8–250 Menthone 250 250 1000 1000 250–>1000 250–>1000 Linalool 125 250 125 250 62.5–500 62.5–500 1,8-Cineole 125 250 >1000 >1000 >1000 250–>1000 Limonene 62.5 125 500 1000 250–1000 125–1000 (R)-(−)-Carvone 62.5 125 31.3 62.5 15.6–125 31.3–125 Dihydrocarvone (E + Z) 125 125 500 1000 125–1000 125–1000 Metronidazole 31.3 31.3 7.8 31.3 1.95–250 7.8–250 * MIC—minimum inhibitory concentration, MBC—minimum bactericidal concentration, MIC50 and MIC90—the minimum concentration at which 50% and 90% of the isolates were inhibited, respectively. ..



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