Journal: Alzheimer's & Dementia
Article Title: Combining plasma p‐tau 231 and glial fibrillary acidic protein produces higher discriminative accuracy for amyloid positivity than other blood‐based biomarker combinations
doi: 10.1002/alz.70796
Figure Lengend Snippet: ROC curve for plasma P‐tau231 + GFAP predicting CSF amyloid positivity. Area under the ROC curve = 0.89. CSF, cerebrospinal fluid; GFAP, glial fibrillary acidic protein; p‐tau, phosphorylated tau; ROC, receiver operating characteristic.
Article Snippet: CSF samples were examined using commercially accessible enzyme‐linked immunosorbent assays (Fujirebio, Ghent, Belgium) to measure CSF concentrations of Aβ 42 (Lumipulse G β‐Amyloid 1‐42 ) and Aβ 40 (Lumipulse G β‐Amyloid 1‐40 ).
Techniques: Clinical Proteomics