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Application of nanomaterials in AD therapy

Journal: Neural Regeneration Research

Article Title: Nanomaterials-mediated lysosomal regulation: a robust protein-clearance approach for the treatment of Alzheimer’s disease

doi: 10.4103/NRR.NRR-D-23-01736

Figure Lengend Snippet: Application of nanomaterials in AD therapy

Article Snippet: Liposomal NPs , 25–10000 , Spherical structure, phospholipid bilayer , Nontoxic, nonimmunogenic, easy to target , Aβ clearance, acetylcholine lipase inhibition , Intravenous injection/Sprague-Dawley rats, bEnd.3 cells, primary rat glia, primary rat neuronal cells , WO 2014 076709A1 , Conjugated to cell-penetrating peptides such as TAT, pVec, and QL , Agrawal et al., 2017; Dos Santos Rodrigues et al., 2019.

Techniques: Inhibition, Injection, Polymer, Antioxidant Activity Assay