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Illumina Inc ldlrko mice
Altered plasma lipoprotein profile in <t>FMO3</t> ASO-treated <t>LDLRKO</t> mice fed a Western diet. FPLC was used to fractionate pooled plasma samples (five individual samples per pool) from LDLRKO mice treated with the control ASO or the FMO3 ASO and fed the Western diet. TG (A), TC (B), and phosphatidylcholine (C) concentrations of each FPLC fraction were measured and shown.
Ldlrko Mice, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1) Product Images from "Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis [S]"

Article Title: Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis [S]

Journal: Journal of Lipid Research

doi: 10.1194/jlr.M051680

Altered plasma lipoprotein profile in FMO3 ASO-treated LDLRKO mice fed a Western diet. FPLC was used to fractionate pooled plasma samples (five individual samples per pool) from LDLRKO mice treated with the control ASO or the FMO3 ASO and fed the Western diet. TG (A), TC (B), and phosphatidylcholine (C) concentrations of each FPLC fraction were measured and shown.
Figure Legend Snippet: Altered plasma lipoprotein profile in FMO3 ASO-treated LDLRKO mice fed a Western diet. FPLC was used to fractionate pooled plasma samples (five individual samples per pool) from LDLRKO mice treated with the control ASO or the FMO3 ASO and fed the Western diet. TG (A), TC (B), and phosphatidylcholine (C) concentrations of each FPLC fraction were measured and shown.

Techniques Used: Allele-specific Oligonucleotide, Mouse Assay, Western Blot, Fast Protein Liquid Chromatography

FMO3 knockdown in LDLRKO mice leads to decreased hepatic FMO3 protein and activity levels, altered plasma TMAO and TMA levels, and decreased adiposity. A: Liver FMO3 protein levels of mice treated with saline (S), control ASO (control), or FMO3 ASO (FMO3) were determined by immunoblotting. B: Liver FMO activity (n = 6 for each group) was determined using TMA as the substrate. Plasma TMAO (C) and TMA (D) levels were determined by mass spectrometry (n = 12 for each group). Body weight (E) and percent weight of four fat pads (gonadal, retroperitoneal, subcutaneous, and mesentery fat pads) (F) were normalized by the body weight (n = 12 for each group). Student’s t -test: # P
Figure Legend Snippet: FMO3 knockdown in LDLRKO mice leads to decreased hepatic FMO3 protein and activity levels, altered plasma TMAO and TMA levels, and decreased adiposity. A: Liver FMO3 protein levels of mice treated with saline (S), control ASO (control), or FMO3 ASO (FMO3) were determined by immunoblotting. B: Liver FMO activity (n = 6 for each group) was determined using TMA as the substrate. Plasma TMAO (C) and TMA (D) levels were determined by mass spectrometry (n = 12 for each group). Body weight (E) and percent weight of four fat pads (gonadal, retroperitoneal, subcutaneous, and mesentery fat pads) (F) were normalized by the body weight (n = 12 for each group). Student’s t -test: # P

Techniques Used: Mouse Assay, Activity Assay, Allele-specific Oligonucleotide, Mass Spectrometry

Related Articles

Allele-specific Oligonucleotide:

Article Title: Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis [S]
Article Snippet: .. Total RNA samples from the livers of LDLRKO mice treated with control or FMO3 ASO (n = 4 for each group) were prepared for use in Illumina MouseRef-8 v2.0 Expression BeadChips according to manufacturer’s recommendations at the Neuroscience Genomics Core at UCLA. ..

Expressing:

Article Title: Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis [S]
Article Snippet: .. Total RNA samples from the livers of LDLRKO mice treated with control or FMO3 ASO (n = 4 for each group) were prepared for use in Illumina MouseRef-8 v2.0 Expression BeadChips according to manufacturer’s recommendations at the Neuroscience Genomics Core at UCLA. ..

Mouse Assay:

Article Title: Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis [S]
Article Snippet: .. Total RNA samples from the livers of LDLRKO mice treated with control or FMO3 ASO (n = 4 for each group) were prepared for use in Illumina MouseRef-8 v2.0 Expression BeadChips according to manufacturer’s recommendations at the Neuroscience Genomics Core at UCLA. ..

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    Illumina Inc ldlrko mice
    Altered plasma lipoprotein profile in <t>FMO3</t> ASO-treated <t>LDLRKO</t> mice fed a Western diet. FPLC was used to fractionate pooled plasma samples (five individual samples per pool) from LDLRKO mice treated with the control ASO or the FMO3 ASO and fed the Western diet. TG (A), TC (B), and phosphatidylcholine (C) concentrations of each FPLC fraction were measured and shown.
    Ldlrko Mice, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ldlrko mice/product/Illumina Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    ldlrko mice - by Bioz Stars, 2020-05
    86/100 stars
      Buy from Supplier

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    Altered plasma lipoprotein profile in FMO3 ASO-treated LDLRKO mice fed a Western diet. FPLC was used to fractionate pooled plasma samples (five individual samples per pool) from LDLRKO mice treated with the control ASO or the FMO3 ASO and fed the Western diet. TG (A), TC (B), and phosphatidylcholine (C) concentrations of each FPLC fraction were measured and shown.

    Journal: Journal of Lipid Research

    Article Title: Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis [S]

    doi: 10.1194/jlr.M051680

    Figure Lengend Snippet: Altered plasma lipoprotein profile in FMO3 ASO-treated LDLRKO mice fed a Western diet. FPLC was used to fractionate pooled plasma samples (five individual samples per pool) from LDLRKO mice treated with the control ASO or the FMO3 ASO and fed the Western diet. TG (A), TC (B), and phosphatidylcholine (C) concentrations of each FPLC fraction were measured and shown.

    Article Snippet: Total RNA samples from the livers of LDLRKO mice treated with control or FMO3 ASO (n = 4 for each group) were prepared for use in Illumina MouseRef-8 v2.0 Expression BeadChips according to manufacturer’s recommendations at the Neuroscience Genomics Core at UCLA.

    Techniques: Allele-specific Oligonucleotide, Mouse Assay, Western Blot, Fast Protein Liquid Chromatography

    FMO3 knockdown in LDLRKO mice leads to decreased hepatic FMO3 protein and activity levels, altered plasma TMAO and TMA levels, and decreased adiposity. A: Liver FMO3 protein levels of mice treated with saline (S), control ASO (control), or FMO3 ASO (FMO3) were determined by immunoblotting. B: Liver FMO activity (n = 6 for each group) was determined using TMA as the substrate. Plasma TMAO (C) and TMA (D) levels were determined by mass spectrometry (n = 12 for each group). Body weight (E) and percent weight of four fat pads (gonadal, retroperitoneal, subcutaneous, and mesentery fat pads) (F) were normalized by the body weight (n = 12 for each group). Student’s t -test: # P

    Journal: Journal of Lipid Research

    Article Title: Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis [S]

    doi: 10.1194/jlr.M051680

    Figure Lengend Snippet: FMO3 knockdown in LDLRKO mice leads to decreased hepatic FMO3 protein and activity levels, altered plasma TMAO and TMA levels, and decreased adiposity. A: Liver FMO3 protein levels of mice treated with saline (S), control ASO (control), or FMO3 ASO (FMO3) were determined by immunoblotting. B: Liver FMO activity (n = 6 for each group) was determined using TMA as the substrate. Plasma TMAO (C) and TMA (D) levels were determined by mass spectrometry (n = 12 for each group). Body weight (E) and percent weight of four fat pads (gonadal, retroperitoneal, subcutaneous, and mesentery fat pads) (F) were normalized by the body weight (n = 12 for each group). Student’s t -test: # P

    Article Snippet: Total RNA samples from the livers of LDLRKO mice treated with control or FMO3 ASO (n = 4 for each group) were prepared for use in Illumina MouseRef-8 v2.0 Expression BeadChips according to manufacturer’s recommendations at the Neuroscience Genomics Core at UCLA.

    Techniques: Mouse Assay, Activity Assay, Allele-specific Oligonucleotide, Mass Spectrometry