Journal: Nature Communications
Article Title: Chronic inflammation degrades CD4 T cell immunity to prior vaccines in treated HIV infection
doi: 10.1038/s41467-024-54605-3
Figure Lengend Snippet: A Plasma levels of CRP, CXCL13, IFNγ, IL-4, IL-6, IL-8, IL10, IL12, MIP1β and TNF. B Plasma levels of sCD14, sCD163, IFABP and LBP. C Blood frequencies of HLA-DR + , PD-1 + and CD57 + CD4 or CD8 T cells as well as frequencies of CD56 high NK cells and monocytes. Circles represent individual participants (33 HU; 34 HIV), medians and IQR are shown, comparison between groups was performed by two-tailed Mann–Whitney tests and P -values of comparisons are presented. D Fold differences of univariate comparisons for plasma markers and cell frequencies between HIV-CMV seropositive and HU-CMV seropositive participants as determined by two-tailed Mann–Whitney tests without adjustment for multiple comparison. Source data are provided as a Source Data file.
Article Snippet: Plasma concentrations of LBP, CRP and CXCL-13 were measured by Human Magnetic Luminex Assay according to the manufacturer’s instructions (R&D Systems).
Techniques: Comparison, Two Tailed Test, MANN-WHITNEY