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DDC Medical lapc 4 cells
Functional Characterization of Total MEIS Knockdown <t>LAPC-4</t> Cells (A) Assessment of MEIS1 and MEIS2 knockdown in LAPC-4 cell using RT-PCR (top) and Western blot analysis (bottom). Two shRNA constructs against MEIS1 and two shRNA constructs against MEIS2 were utilized to control for off-target effects. To determine MEIS1 and MEIS2 protein levels after shRNA depletion, western blot analyses was conducted using a mouse monoclonal targeting both MEIS1 and MEIS2 (Pan-MEIS). (B) Xenograft growth of MEIS1 and MEIS2 double knockdown LAPC-4 cells injected subcutaneously on the flanks of hormonally-intact male nude mice compared to non-silencing controls. Differences in tumor volumes at days 25, 27 and 29 post-injection were statistically significant (Control N=8; double knockdown N=8; * p -value
Lapc 4 Cells, supplied by DDC Medical, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/lapc 4 cells/product/DDC Medical
Average 91 stars, based on 1 article reviews
Price from $9.99 to $1999.99
lapc 4 cells - by Bioz Stars, 2021-01
91/100 stars

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1) Product Images from "MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease"

Article Title: MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

doi: 10.1158/1078-0432.CCR-17-3673

Functional Characterization of Total MEIS Knockdown LAPC-4 Cells (A) Assessment of MEIS1 and MEIS2 knockdown in LAPC-4 cell using RT-PCR (top) and Western blot analysis (bottom). Two shRNA constructs against MEIS1 and two shRNA constructs against MEIS2 were utilized to control for off-target effects. To determine MEIS1 and MEIS2 protein levels after shRNA depletion, western blot analyses was conducted using a mouse monoclonal targeting both MEIS1 and MEIS2 (Pan-MEIS). (B) Xenograft growth of MEIS1 and MEIS2 double knockdown LAPC-4 cells injected subcutaneously on the flanks of hormonally-intact male nude mice compared to non-silencing controls. Differences in tumor volumes at days 25, 27 and 29 post-injection were statistically significant (Control N=8; double knockdown N=8; * p -value
Figure Legend Snippet: Functional Characterization of Total MEIS Knockdown LAPC-4 Cells (A) Assessment of MEIS1 and MEIS2 knockdown in LAPC-4 cell using RT-PCR (top) and Western blot analysis (bottom). Two shRNA constructs against MEIS1 and two shRNA constructs against MEIS2 were utilized to control for off-target effects. To determine MEIS1 and MEIS2 protein levels after shRNA depletion, western blot analyses was conducted using a mouse monoclonal targeting both MEIS1 and MEIS2 (Pan-MEIS). (B) Xenograft growth of MEIS1 and MEIS2 double knockdown LAPC-4 cells injected subcutaneously on the flanks of hormonally-intact male nude mice compared to non-silencing controls. Differences in tumor volumes at days 25, 27 and 29 post-injection were statistically significant (Control N=8; double knockdown N=8; * p -value

Techniques Used: Functional Assay, Reverse Transcription Polymerase Chain Reaction, Western Blot, shRNA, Construct, Injection, Mouse Assay

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    DDC Medical lapc 4 cells
    Functional Characterization of Total MEIS Knockdown <t>LAPC-4</t> Cells (A) Assessment of MEIS1 and MEIS2 knockdown in LAPC-4 cell using RT-PCR (top) and Western blot analysis (bottom). Two shRNA constructs against MEIS1 and two shRNA constructs against MEIS2 were utilized to control for off-target effects. To determine MEIS1 and MEIS2 protein levels after shRNA depletion, western blot analyses was conducted using a mouse monoclonal targeting both MEIS1 and MEIS2 (Pan-MEIS). (B) Xenograft growth of MEIS1 and MEIS2 double knockdown LAPC-4 cells injected subcutaneously on the flanks of hormonally-intact male nude mice compared to non-silencing controls. Differences in tumor volumes at days 25, 27 and 29 post-injection were statistically significant (Control N=8; double knockdown N=8; * p -value
    Lapc 4 Cells, supplied by DDC Medical, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/lapc 4 cells/product/DDC Medical
    Average 91 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    lapc 4 cells - by Bioz Stars, 2021-01
    91/100 stars
      Buy from Supplier

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    Functional Characterization of Total MEIS Knockdown LAPC-4 Cells (A) Assessment of MEIS1 and MEIS2 knockdown in LAPC-4 cell using RT-PCR (top) and Western blot analysis (bottom). Two shRNA constructs against MEIS1 and two shRNA constructs against MEIS2 were utilized to control for off-target effects. To determine MEIS1 and MEIS2 protein levels after shRNA depletion, western blot analyses was conducted using a mouse monoclonal targeting both MEIS1 and MEIS2 (Pan-MEIS). (B) Xenograft growth of MEIS1 and MEIS2 double knockdown LAPC-4 cells injected subcutaneously on the flanks of hormonally-intact male nude mice compared to non-silencing controls. Differences in tumor volumes at days 25, 27 and 29 post-injection were statistically significant (Control N=8; double knockdown N=8; * p -value

    Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

    Article Title: MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease

    doi: 10.1158/1078-0432.CCR-17-3673

    Figure Lengend Snippet: Functional Characterization of Total MEIS Knockdown LAPC-4 Cells (A) Assessment of MEIS1 and MEIS2 knockdown in LAPC-4 cell using RT-PCR (top) and Western blot analysis (bottom). Two shRNA constructs against MEIS1 and two shRNA constructs against MEIS2 were utilized to control for off-target effects. To determine MEIS1 and MEIS2 protein levels after shRNA depletion, western blot analyses was conducted using a mouse monoclonal targeting both MEIS1 and MEIS2 (Pan-MEIS). (B) Xenograft growth of MEIS1 and MEIS2 double knockdown LAPC-4 cells injected subcutaneously on the flanks of hormonally-intact male nude mice compared to non-silencing controls. Differences in tumor volumes at days 25, 27 and 29 post-injection were statistically significant (Control N=8; double knockdown N=8; * p -value

    Article Snippet: Cell authentication of LAPC-4 cells was confirmed via DDC Medical services (Fairfield, OH).

    Techniques: Functional Assay, Reverse Transcription Polymerase Chain Reaction, Western Blot, shRNA, Construct, Injection, Mouse Assay