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kmrc 1  (ATCC)


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    Structured Review

    ATCC kmrc 1
    ( A ) Epigenomic datasets generated from 4 tRCC (s-TFE, FU-UR-1, UOK109, and UOK146) and 6 ccRCC (Caki-1, A-498, RFX393, 786-O, 769-P, and <t>KMRC-1)</t> cell lines, either in-house or in a previously published study ( , ). ( B ) Unsupervised hierarchical clustering of the H3K4me3 ChIP-seq, H3K27ac ChIP-seq, and MeDIP-seq consensus peaks across tRCC and ccRCC cell lines analyzed in this study. ( C ) Volcano plots showing differentially marked peaks between tRCC and ccRCC cell lines for H3K4me3 ChIP-Seq, H3K27ac ChIP-seq, and MeDIP-seq. Thresholds for significance were set at FDR-q < 0.01 and log 2 FC > 1 for H3K27ac and MeDIP and > 2 for H3K4me3.
    Kmrc 1, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1618 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Images

    1) Product Images from "Cell-free DNA epigenomic profiling enables noninvasive detection and monitoring of translocation renal cell carcinoma"

    Article Title: Cell-free DNA epigenomic profiling enables noninvasive detection and monitoring of translocation renal cell carcinoma

    Journal: The Journal of Clinical Investigation

    doi: 10.1172/JCI195725

    ( A ) Epigenomic datasets generated from 4 tRCC (s-TFE, FU-UR-1, UOK109, and UOK146) and 6 ccRCC (Caki-1, A-498, RFX393, 786-O, 769-P, and KMRC-1) cell lines, either in-house or in a previously published study ( , ). ( B ) Unsupervised hierarchical clustering of the H3K4me3 ChIP-seq, H3K27ac ChIP-seq, and MeDIP-seq consensus peaks across tRCC and ccRCC cell lines analyzed in this study. ( C ) Volcano plots showing differentially marked peaks between tRCC and ccRCC cell lines for H3K4me3 ChIP-Seq, H3K27ac ChIP-seq, and MeDIP-seq. Thresholds for significance were set at FDR-q < 0.01 and log 2 FC > 1 for H3K27ac and MeDIP and > 2 for H3K4me3.
    Figure Legend Snippet: ( A ) Epigenomic datasets generated from 4 tRCC (s-TFE, FU-UR-1, UOK109, and UOK146) and 6 ccRCC (Caki-1, A-498, RFX393, 786-O, 769-P, and KMRC-1) cell lines, either in-house or in a previously published study ( , ). ( B ) Unsupervised hierarchical clustering of the H3K4me3 ChIP-seq, H3K27ac ChIP-seq, and MeDIP-seq consensus peaks across tRCC and ccRCC cell lines analyzed in this study. ( C ) Volcano plots showing differentially marked peaks between tRCC and ccRCC cell lines for H3K4me3 ChIP-Seq, H3K27ac ChIP-seq, and MeDIP-seq. Thresholds for significance were set at FDR-q < 0.01 and log 2 FC > 1 for H3K27ac and MeDIP and > 2 for H3K4me3.

    Techniques Used: Generated, ChIP-sequencing, Methylated DNA Immunoprecipitation



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    Image Search Results


    ( A ) Epigenomic datasets generated from 4 tRCC (s-TFE, FU-UR-1, UOK109, and UOK146) and 6 ccRCC (Caki-1, A-498, RFX393, 786-O, 769-P, and KMRC-1) cell lines, either in-house or in a previously published study ( , ). ( B ) Unsupervised hierarchical clustering of the H3K4me3 ChIP-seq, H3K27ac ChIP-seq, and MeDIP-seq consensus peaks across tRCC and ccRCC cell lines analyzed in this study. ( C ) Volcano plots showing differentially marked peaks between tRCC and ccRCC cell lines for H3K4me3 ChIP-Seq, H3K27ac ChIP-seq, and MeDIP-seq. Thresholds for significance were set at FDR-q < 0.01 and log 2 FC > 1 for H3K27ac and MeDIP and > 2 for H3K4me3.

    Journal: The Journal of Clinical Investigation

    Article Title: Cell-free DNA epigenomic profiling enables noninvasive detection and monitoring of translocation renal cell carcinoma

    doi: 10.1172/JCI195725

    Figure Lengend Snippet: ( A ) Epigenomic datasets generated from 4 tRCC (s-TFE, FU-UR-1, UOK109, and UOK146) and 6 ccRCC (Caki-1, A-498, RFX393, 786-O, 769-P, and KMRC-1) cell lines, either in-house or in a previously published study ( , ). ( B ) Unsupervised hierarchical clustering of the H3K4me3 ChIP-seq, H3K27ac ChIP-seq, and MeDIP-seq consensus peaks across tRCC and ccRCC cell lines analyzed in this study. ( C ) Volcano plots showing differentially marked peaks between tRCC and ccRCC cell lines for H3K4me3 ChIP-Seq, H3K27ac ChIP-seq, and MeDIP-seq. Thresholds for significance were set at FDR-q < 0.01 and log 2 FC > 1 for H3K27ac and MeDIP and > 2 for H3K4me3.

    Article Snippet: The cell lines 786-O (ATCC, CRL-1932; RRID: CVCL_1051), 293T (ATCC, CRL-11268; RRID: CVCL_0063), A-498 (ATCC, HTB-44; RRID: CVCL_1056), 769-P (ATCC, CRL-1933; RRID: CVCL_1050), KMRC-1 (JCRB1010; RRID: CVCL_2983), Caki-1 (ATCC, HTB-46; RRID: CVCL_0234), UOK109 (RRID: CVCL_B123), and UOK146 (RRID: CVCL_B123) were obtained from W. Marston Linehan’s laboratory (National Cancer Institute).

    Techniques: Generated, ChIP-sequencing, Methylated DNA Immunoprecipitation