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Association of parasite clearance half-life and <t>Kelch13</t> Status (PP analysis set). Vietnam ( blue circles ), Africa ( red circles ), median ( black line ), C580Y + P553L polyclonal infection. Note that the plot includes only patients with both genotyping and PCt1/2 results
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Association of parasite clearance half-life and Kelch13 Status (PP analysis set). Vietnam ( blue circles ), Africa ( red circles ), median ( black line ), C580Y + P553L polyclonal infection. Note that the plot includes only patients with both genotyping and PCt1/2 results

Journal: BMC Medicine

Article Title: A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria

doi: 10.1186/s12916-017-0940-3

Figure Lengend Snippet: Association of parasite clearance half-life and Kelch13 Status (PP analysis set). Vietnam ( blue circles ), Africa ( red circles ), median ( black line ), C580Y + P553L polyclonal infection. Note that the plot includes only patients with both genotyping and PCt1/2 results

Article Snippet: Kelch13 genotyping (baseline) was determined by the method of the Pasteur Institute [ ], PCt1/2 was calculated using the WWARN calculator [ ] and the relationship between Kelch13 genotype and PCt1/2 was explored by site and by mutation graphically, and summary statistics reported.

Techniques: Infection