iodophenpropit  (Alomone Labs)


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    Alomone Labs iodophenpropit
    The excitation induced by H1 receptor activation is enhanced in the ipsilesional MVN GABAergic projection neurons of the commissural inhibitory system after UL. A , Schematic representation of experimental design. B , Identification of the GABAergic MVN commissural neurons recorded in brain slices. The retrogradely labeled MVN neurons on the contralateral side of FG injection were current-clamped and injected with biocytin. The recorded neurons with triple immunopositive for biocytin (green), GAD67 (blue), and FG (red) were identified as the GABAergic commissural inhibitory neurons. C , D , PSTHs show that activation of H1 receptor by application of histamine in the presence of ranitidine (H2 receptor antagonist) and <t>iodophenpropit</t> (H3 receptor antagonist) induced a concentration-dependent excitation on the ipsilesional ( C ) and contralesional ( D ) GABAergic MVN commissural neurons with different amplitudes. The inset of each PSTH represents the raw data of peak firing. E , Concentration-response curves for histamine in the presence of ranitidine and iodophenpropit on the recorded ipsilesional (red) and contralesional (black) GABAergic MVN commissural neurons. F , Identification of the glutamatergic MVN commissural neurons recorded in brain slices. The recorded neurons with triple immunopositive for biocytin (green), glutamate (blue), and FG (red) were identified as the glutamatergic commissural excitatory neurons ( F ). G , H , PSTHs show that activation of H1 receptor by application of histamine in the presence of ranitidine and iodophenpropit induced a concentration-dependent excitation on the ipsilesional ( G ) and contralesional ( H ) glutamatergic MVN commissural neurons with similar amplitudes. The inset of each PSTH represents the raw data of peak firing. I , Concentration-response curves for histamine in the presence of ranitidine and iodophenpropit on the recorded ipsilesional (green) and contralesional (black) glutaminergic MVN commissural neurons. Data represent mean ± SEM. ** p
    Iodophenpropit, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/iodophenpropit/product/Alomone Labs
    Average 91 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    iodophenpropit - by Bioz Stars, 2022-09
    91/100 stars

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    1) Product Images from "Histamine H1 Receptor Contributes to Vestibular Compensation"

    Article Title: Histamine H1 Receptor Contributes to Vestibular Compensation

    Journal: The Journal of Neuroscience

    doi: 10.1523/JNEUROSCI.1350-18.2018

    The excitation induced by H1 receptor activation is enhanced in the ipsilesional MVN GABAergic projection neurons of the commissural inhibitory system after UL. A , Schematic representation of experimental design. B , Identification of the GABAergic MVN commissural neurons recorded in brain slices. The retrogradely labeled MVN neurons on the contralateral side of FG injection were current-clamped and injected with biocytin. The recorded neurons with triple immunopositive for biocytin (green), GAD67 (blue), and FG (red) were identified as the GABAergic commissural inhibitory neurons. C , D , PSTHs show that activation of H1 receptor by application of histamine in the presence of ranitidine (H2 receptor antagonist) and iodophenpropit (H3 receptor antagonist) induced a concentration-dependent excitation on the ipsilesional ( C ) and contralesional ( D ) GABAergic MVN commissural neurons with different amplitudes. The inset of each PSTH represents the raw data of peak firing. E , Concentration-response curves for histamine in the presence of ranitidine and iodophenpropit on the recorded ipsilesional (red) and contralesional (black) GABAergic MVN commissural neurons. F , Identification of the glutamatergic MVN commissural neurons recorded in brain slices. The recorded neurons with triple immunopositive for biocytin (green), glutamate (blue), and FG (red) were identified as the glutamatergic commissural excitatory neurons ( F ). G , H , PSTHs show that activation of H1 receptor by application of histamine in the presence of ranitidine and iodophenpropit induced a concentration-dependent excitation on the ipsilesional ( G ) and contralesional ( H ) glutamatergic MVN commissural neurons with similar amplitudes. The inset of each PSTH represents the raw data of peak firing. I , Concentration-response curves for histamine in the presence of ranitidine and iodophenpropit on the recorded ipsilesional (green) and contralesional (black) glutaminergic MVN commissural neurons. Data represent mean ± SEM. ** p
    Figure Legend Snippet: The excitation induced by H1 receptor activation is enhanced in the ipsilesional MVN GABAergic projection neurons of the commissural inhibitory system after UL. A , Schematic representation of experimental design. B , Identification of the GABAergic MVN commissural neurons recorded in brain slices. The retrogradely labeled MVN neurons on the contralateral side of FG injection were current-clamped and injected with biocytin. The recorded neurons with triple immunopositive for biocytin (green), GAD67 (blue), and FG (red) were identified as the GABAergic commissural inhibitory neurons. C , D , PSTHs show that activation of H1 receptor by application of histamine in the presence of ranitidine (H2 receptor antagonist) and iodophenpropit (H3 receptor antagonist) induced a concentration-dependent excitation on the ipsilesional ( C ) and contralesional ( D ) GABAergic MVN commissural neurons with different amplitudes. The inset of each PSTH represents the raw data of peak firing. E , Concentration-response curves for histamine in the presence of ranitidine and iodophenpropit on the recorded ipsilesional (red) and contralesional (black) GABAergic MVN commissural neurons. F , Identification of the glutamatergic MVN commissural neurons recorded in brain slices. The recorded neurons with triple immunopositive for biocytin (green), glutamate (blue), and FG (red) were identified as the glutamatergic commissural excitatory neurons ( F ). G , H , PSTHs show that activation of H1 receptor by application of histamine in the presence of ranitidine and iodophenpropit induced a concentration-dependent excitation on the ipsilesional ( G ) and contralesional ( H ) glutamatergic MVN commissural neurons with similar amplitudes. The inset of each PSTH represents the raw data of peak firing. I , Concentration-response curves for histamine in the presence of ranitidine and iodophenpropit on the recorded ipsilesional (green) and contralesional (black) glutaminergic MVN commissural neurons. Data represent mean ± SEM. ** p

    Techniques Used: Activation Assay, Labeling, Injection, Concentration Assay

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    Alomone Labs iodophenpropit
    The excitation induced by H1 receptor activation is enhanced in the ipsilesional MVN GABAergic projection neurons of the commissural inhibitory system after UL. A , Schematic representation of experimental design. B , Identification of the GABAergic MVN commissural neurons recorded in brain slices. The retrogradely labeled MVN neurons on the contralateral side of FG injection were current-clamped and injected with biocytin. The recorded neurons with triple immunopositive for biocytin (green), GAD67 (blue), and FG (red) were identified as the GABAergic commissural inhibitory neurons. C , D , PSTHs show that activation of H1 receptor by application of histamine in the presence of ranitidine (H2 receptor antagonist) and <t>iodophenpropit</t> (H3 receptor antagonist) induced a concentration-dependent excitation on the ipsilesional ( C ) and contralesional ( D ) GABAergic MVN commissural neurons with different amplitudes. The inset of each PSTH represents the raw data of peak firing. E , Concentration-response curves for histamine in the presence of ranitidine and iodophenpropit on the recorded ipsilesional (red) and contralesional (black) GABAergic MVN commissural neurons. F , Identification of the glutamatergic MVN commissural neurons recorded in brain slices. The recorded neurons with triple immunopositive for biocytin (green), glutamate (blue), and FG (red) were identified as the glutamatergic commissural excitatory neurons ( F ). G , H , PSTHs show that activation of H1 receptor by application of histamine in the presence of ranitidine and iodophenpropit induced a concentration-dependent excitation on the ipsilesional ( G ) and contralesional ( H ) glutamatergic MVN commissural neurons with similar amplitudes. The inset of each PSTH represents the raw data of peak firing. I , Concentration-response curves for histamine in the presence of ranitidine and iodophenpropit on the recorded ipsilesional (green) and contralesional (black) glutaminergic MVN commissural neurons. Data represent mean ± SEM. ** p
    Iodophenpropit, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/iodophenpropit/product/Alomone Labs
    Average 91 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    iodophenpropit - by Bioz Stars, 2022-09
    91/100 stars
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    The excitation induced by H1 receptor activation is enhanced in the ipsilesional MVN GABAergic projection neurons of the commissural inhibitory system after UL. A , Schematic representation of experimental design. B , Identification of the GABAergic MVN commissural neurons recorded in brain slices. The retrogradely labeled MVN neurons on the contralateral side of FG injection were current-clamped and injected with biocytin. The recorded neurons with triple immunopositive for biocytin (green), GAD67 (blue), and FG (red) were identified as the GABAergic commissural inhibitory neurons. C , D , PSTHs show that activation of H1 receptor by application of histamine in the presence of ranitidine (H2 receptor antagonist) and iodophenpropit (H3 receptor antagonist) induced a concentration-dependent excitation on the ipsilesional ( C ) and contralesional ( D ) GABAergic MVN commissural neurons with different amplitudes. The inset of each PSTH represents the raw data of peak firing. E , Concentration-response curves for histamine in the presence of ranitidine and iodophenpropit on the recorded ipsilesional (red) and contralesional (black) GABAergic MVN commissural neurons. F , Identification of the glutamatergic MVN commissural neurons recorded in brain slices. The recorded neurons with triple immunopositive for biocytin (green), glutamate (blue), and FG (red) were identified as the glutamatergic commissural excitatory neurons ( F ). G , H , PSTHs show that activation of H1 receptor by application of histamine in the presence of ranitidine and iodophenpropit induced a concentration-dependent excitation on the ipsilesional ( G ) and contralesional ( H ) glutamatergic MVN commissural neurons with similar amplitudes. The inset of each PSTH represents the raw data of peak firing. I , Concentration-response curves for histamine in the presence of ranitidine and iodophenpropit on the recorded ipsilesional (green) and contralesional (black) glutaminergic MVN commissural neurons. Data represent mean ± SEM. ** p

    Journal: The Journal of Neuroscience

    Article Title: Histamine H1 Receptor Contributes to Vestibular Compensation

    doi: 10.1523/JNEUROSCI.1350-18.2018

    Figure Lengend Snippet: The excitation induced by H1 receptor activation is enhanced in the ipsilesional MVN GABAergic projection neurons of the commissural inhibitory system after UL. A , Schematic representation of experimental design. B , Identification of the GABAergic MVN commissural neurons recorded in brain slices. The retrogradely labeled MVN neurons on the contralateral side of FG injection were current-clamped and injected with biocytin. The recorded neurons with triple immunopositive for biocytin (green), GAD67 (blue), and FG (red) were identified as the GABAergic commissural inhibitory neurons. C , D , PSTHs show that activation of H1 receptor by application of histamine in the presence of ranitidine (H2 receptor antagonist) and iodophenpropit (H3 receptor antagonist) induced a concentration-dependent excitation on the ipsilesional ( C ) and contralesional ( D ) GABAergic MVN commissural neurons with different amplitudes. The inset of each PSTH represents the raw data of peak firing. E , Concentration-response curves for histamine in the presence of ranitidine and iodophenpropit on the recorded ipsilesional (red) and contralesional (black) GABAergic MVN commissural neurons. F , Identification of the glutamatergic MVN commissural neurons recorded in brain slices. The recorded neurons with triple immunopositive for biocytin (green), glutamate (blue), and FG (red) were identified as the glutamatergic commissural excitatory neurons ( F ). G , H , PSTHs show that activation of H1 receptor by application of histamine in the presence of ranitidine and iodophenpropit induced a concentration-dependent excitation on the ipsilesional ( G ) and contralesional ( H ) glutamatergic MVN commissural neurons with similar amplitudes. The inset of each PSTH represents the raw data of peak firing. I , Concentration-response curves for histamine in the presence of ranitidine and iodophenpropit on the recorded ipsilesional (green) and contralesional (black) glutaminergic MVN commissural neurons. Data represent mean ± SEM. ** p

    Article Snippet: Ranitidine (0.3 μ m , Alomone Labs) and iodophenpropit (0.3 μ m , Alomone Labs), selective antagonists for histamine H2 and H3 receptor, respectively, were coapplied to isolate the effect mediated by H1 receptor.

    Techniques: Activation Assay, Labeling, Injection, Concentration Assay