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Santa Cruz Biotechnology integrin β1 sirna 2
Migration and invasion of gastric cancer cells is impacted by galectin-1 (Gal-1) expression in carcinoma-associated fibroblasts (CAFs). (a, b) CAF-treated cancer cells showed higher migration than untreated cells ( P < 0.05), and this effect was inhibited by reducing the expression of Gal-1 in CAFs with Gal-1 siRNA-1 and <t>siRNA-2</t> compared with the normal control (NC) siRNA-treated group ( P < 0.05). (c, d) CAF-treated cancer cells showed higher invasiveness than untreated cells ( P < 0.05), and this effect was inhibited by reducing the Gal-1 expression as in (a) and (b). (a, c) Magnification, ×200.
Integrin β1 Sirna 2, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/integrin β1 sirna 2/product/Santa Cruz Biotechnology
Average 93 stars, based on 1 article reviews
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integrin β1 sirna 2 - by Bioz Stars, 2023-09
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Article Title: Expression of galectin-1 in carcinoma-associated fibroblasts promotes gastric cancer cell invasion through upregulation of integrin β1

Journal: Cancer Science

doi: 10.1111/cas.12539

Migration and invasion of gastric cancer cells is impacted by galectin-1 (Gal-1) expression in carcinoma-associated fibroblasts (CAFs). (a, b) CAF-treated cancer cells showed higher migration than untreated cells ( P < 0.05), and this effect was inhibited by reducing the expression of Gal-1 in CAFs with Gal-1 siRNA-1 and siRNA-2 compared with the normal control (NC) siRNA-treated group ( P < 0.05). (c, d) CAF-treated cancer cells showed higher invasiveness than untreated cells ( P < 0.05), and this effect was inhibited by reducing the Gal-1 expression as in (a) and (b). (a, c) Magnification, ×200.
Figure Legend Snippet: Migration and invasion of gastric cancer cells is impacted by galectin-1 (Gal-1) expression in carcinoma-associated fibroblasts (CAFs). (a, b) CAF-treated cancer cells showed higher migration than untreated cells ( P < 0.05), and this effect was inhibited by reducing the expression of Gal-1 in CAFs with Gal-1 siRNA-1 and siRNA-2 compared with the normal control (NC) siRNA-treated group ( P < 0.05). (c, d) CAF-treated cancer cells showed higher invasiveness than untreated cells ( P < 0.05), and this effect was inhibited by reducing the Gal-1 expression as in (a) and (b). (a, c) Magnification, ×200.

Techniques Used: Migration, Expressing

Candidate genes associated with galectin-1-induced cell migration and invasion. Integrin β1 was elevated at both the mRNA and protein level when gastric cancer cells were co-cultured with carcinoma-associated fibroblasts (CAFs), and this was markedly reduced when the CAFs were pre-transfected with galectin-1 siRNA-1 and siRNA-2. (a) Real-time PCR results. (b) Western blotting results.
Figure Legend Snippet: Candidate genes associated with galectin-1-induced cell migration and invasion. Integrin β1 was elevated at both the mRNA and protein level when gastric cancer cells were co-cultured with carcinoma-associated fibroblasts (CAFs), and this was markedly reduced when the CAFs were pre-transfected with galectin-1 siRNA-1 and siRNA-2. (a) Real-time PCR results. (b) Western blotting results.

Techniques Used: Migration, Cell Culture, Transfection, Real-time Polymerase Chain Reaction, Western Blot

Validation of siRNA transfection efficiency and the involvement of integrin β1 in the enhanced invasion of human gastric cancer cells induced by carcinoma-associated fibroblasts (CAFs). (a) Western blot validation of the transfection efficiency of galectin-1 siRNA-1 and siRNA-2 in CAFs. (b) Western blot validation of the transfection efficiency of integrin β1 siRNA-1 and siRNA-2 in gastric cancer cells. (c) Pre-blockade of integrin β1 expression in gastric cancer cells by siRNA-1 and siRNA-2 interrupted the invasion-promoting effect of CAFs that highly express galectin-1. NC, normal control. Magnification, ×200.
Figure Legend Snippet: Validation of siRNA transfection efficiency and the involvement of integrin β1 in the enhanced invasion of human gastric cancer cells induced by carcinoma-associated fibroblasts (CAFs). (a) Western blot validation of the transfection efficiency of galectin-1 siRNA-1 and siRNA-2 in CAFs. (b) Western blot validation of the transfection efficiency of integrin β1 siRNA-1 and siRNA-2 in gastric cancer cells. (c) Pre-blockade of integrin β1 expression in gastric cancer cells by siRNA-1 and siRNA-2 interrupted the invasion-promoting effect of CAFs that highly express galectin-1. NC, normal control. Magnification, ×200.

Techniques Used: Transfection, Western Blot, Expressing

Immunohistochemical staining for galectin-1 (a–d) and integrin β1 (e–h) in gastric cancer tissues. Negative (a), weak (b), moderate (c), and strong (d) galectin-1 staining. Negative (e), weak (f), moderate (g), and strong (h) integrin β1staining. Original magnification, ×200.
Figure Legend Snippet: Immunohistochemical staining for galectin-1 (a–d) and integrin β1 (e–h) in gastric cancer tissues. Negative (a), weak (b), moderate (c), and strong (d) galectin-1 staining. Negative (e), weak (f), moderate (g), and strong (h) integrin β1staining. Original magnification, ×200.

Techniques Used: Immunohistochemical staining, Staining

Kaplan–Meier survival curves of galectin-1 (Gal-1) and integrin β1 expression in gastric cancer patients. Cumulative 5-year survival rate.
Figure Legend Snippet: Kaplan–Meier survival curves of galectin-1 (Gal-1) and integrin β1 expression in gastric cancer patients. Cumulative 5-year survival rate.

Techniques Used: Expressing


Structured Review

Santa Cruz Biotechnology β1 integrin sirna c3h10t1 2 cells
β1 Integrin Sirna C3h10t1 2 Cells, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/β1 integrin sirna c3h10t1 2 cells/product/Santa Cruz Biotechnology
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
β1 integrin sirna c3h10t1 2 cells - by Bioz Stars, 2023-09
86/100 stars

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Structured Review

Santa Cruz Biotechnology β1 integrin sirna c3h10t1 2 cells
β1 Integrin Sirna C3h10t1 2 Cells, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/β1 integrin sirna c3h10t1 2 cells/product/Santa Cruz Biotechnology
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
β1 integrin sirna c3h10t1 2 cells - by Bioz Stars, 2023-09
86/100 stars

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Structured Review

Santa Cruz Biotechnology β1 integrin sirna c3h10t1 2 cells
β1 Integrin Sirna C3h10t1 2 Cells, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/β1 integrin sirna c3h10t1 2 cells/product/Santa Cruz Biotechnology
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
β1 integrin sirna c3h10t1 2 cells - by Bioz Stars, 2023-09
86/100 stars

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Structured Review

Santa Cruz Biotechnology β5 integrin
β5 Integrin, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/β5 integrin/product/Santa Cruz Biotechnology
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
β5 integrin - by Bioz Stars, 2023-09
93/100 stars

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    Santa Cruz Biotechnology integrin β1 sirna 2
    Migration and invasion of gastric cancer cells is impacted by galectin-1 (Gal-1) expression in carcinoma-associated fibroblasts (CAFs). (a, b) CAF-treated cancer cells showed higher migration than untreated cells ( P < 0.05), and this effect was inhibited by reducing the expression of Gal-1 in CAFs with Gal-1 siRNA-1 and <t>siRNA-2</t> compared with the normal control (NC) siRNA-treated group ( P < 0.05). (c, d) CAF-treated cancer cells showed higher invasiveness than untreated cells ( P < 0.05), and this effect was inhibited by reducing the Gal-1 expression as in (a) and (b). (a, c) Magnification, ×200.
    Integrin β1 Sirna 2, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/integrin β1 sirna 2/product/Santa Cruz Biotechnology
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    integrin β1 sirna 2 - by Bioz Stars, 2023-09
    93/100 stars
      Buy from Supplier

    86
    Santa Cruz Biotechnology β1 integrin sirna c3h10t1 2 cells
    Migration and invasion of gastric cancer cells is impacted by galectin-1 (Gal-1) expression in carcinoma-associated fibroblasts (CAFs). (a, b) CAF-treated cancer cells showed higher migration than untreated cells ( P < 0.05), and this effect was inhibited by reducing the expression of Gal-1 in CAFs with Gal-1 siRNA-1 and <t>siRNA-2</t> compared with the normal control (NC) siRNA-treated group ( P < 0.05). (c, d) CAF-treated cancer cells showed higher invasiveness than untreated cells ( P < 0.05), and this effect was inhibited by reducing the Gal-1 expression as in (a) and (b). (a, c) Magnification, ×200.
    β1 Integrin Sirna C3h10t1 2 Cells, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/β1 integrin sirna c3h10t1 2 cells/product/Santa Cruz Biotechnology
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    β1 integrin sirna c3h10t1 2 cells - by Bioz Stars, 2023-09
    86/100 stars
      Buy from Supplier

    93
    Santa Cruz Biotechnology β5 integrin
    Migration and invasion of gastric cancer cells is impacted by galectin-1 (Gal-1) expression in carcinoma-associated fibroblasts (CAFs). (a, b) CAF-treated cancer cells showed higher migration than untreated cells ( P < 0.05), and this effect was inhibited by reducing the expression of Gal-1 in CAFs with Gal-1 siRNA-1 and <t>siRNA-2</t> compared with the normal control (NC) siRNA-treated group ( P < 0.05). (c, d) CAF-treated cancer cells showed higher invasiveness than untreated cells ( P < 0.05), and this effect was inhibited by reducing the Gal-1 expression as in (a) and (b). (a, c) Magnification, ×200.
    β5 Integrin, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/β5 integrin/product/Santa Cruz Biotechnology
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    β5 integrin - by Bioz Stars, 2023-09
    93/100 stars
      Buy from Supplier

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    Migration and invasion of gastric cancer cells is impacted by galectin-1 (Gal-1) expression in carcinoma-associated fibroblasts (CAFs). (a, b) CAF-treated cancer cells showed higher migration than untreated cells ( P < 0.05), and this effect was inhibited by reducing the expression of Gal-1 in CAFs with Gal-1 siRNA-1 and siRNA-2 compared with the normal control (NC) siRNA-treated group ( P < 0.05). (c, d) CAF-treated cancer cells showed higher invasiveness than untreated cells ( P < 0.05), and this effect was inhibited by reducing the Gal-1 expression as in (a) and (b). (a, c) Magnification, ×200.

    Journal: Cancer Science

    Article Title: Expression of galectin-1 in carcinoma-associated fibroblasts promotes gastric cancer cell invasion through upregulation of integrin β1

    doi: 10.1111/cas.12539

    Figure Lengend Snippet: Migration and invasion of gastric cancer cells is impacted by galectin-1 (Gal-1) expression in carcinoma-associated fibroblasts (CAFs). (a, b) CAF-treated cancer cells showed higher migration than untreated cells ( P < 0.05), and this effect was inhibited by reducing the expression of Gal-1 in CAFs with Gal-1 siRNA-1 and siRNA-2 compared with the normal control (NC) siRNA-treated group ( P < 0.05). (c, d) CAF-treated cancer cells showed higher invasiveness than untreated cells ( P < 0.05), and this effect was inhibited by reducing the Gal-1 expression as in (a) and (b). (a, c) Magnification, ×200.

    Article Snippet: Galectin-1 siRNA-1 (sc-35441; Santa Cruz Biotechnology, Santa Cruz, CA, USA), Gal-1 siRNA-2 (SR302674; OriGene Technologies, Beijing, China), integrin β1 siRNA-1 (sc-35674; Santa Cruz Biotechnology), and integrin β1 siRNA-2 (sc-44310; Santa Cruz Biotechnology) mixed with transfection reagent (sc-29528; Santa Cruz Biotechnology) were used for transfection according to the manufacturer's instructions.

    Techniques: Migration, Expressing

    Candidate genes associated with galectin-1-induced cell migration and invasion. Integrin β1 was elevated at both the mRNA and protein level when gastric cancer cells were co-cultured with carcinoma-associated fibroblasts (CAFs), and this was markedly reduced when the CAFs were pre-transfected with galectin-1 siRNA-1 and siRNA-2. (a) Real-time PCR results. (b) Western blotting results.

    Journal: Cancer Science

    Article Title: Expression of galectin-1 in carcinoma-associated fibroblasts promotes gastric cancer cell invasion through upregulation of integrin β1

    doi: 10.1111/cas.12539

    Figure Lengend Snippet: Candidate genes associated with galectin-1-induced cell migration and invasion. Integrin β1 was elevated at both the mRNA and protein level when gastric cancer cells were co-cultured with carcinoma-associated fibroblasts (CAFs), and this was markedly reduced when the CAFs were pre-transfected with galectin-1 siRNA-1 and siRNA-2. (a) Real-time PCR results. (b) Western blotting results.

    Article Snippet: Galectin-1 siRNA-1 (sc-35441; Santa Cruz Biotechnology, Santa Cruz, CA, USA), Gal-1 siRNA-2 (SR302674; OriGene Technologies, Beijing, China), integrin β1 siRNA-1 (sc-35674; Santa Cruz Biotechnology), and integrin β1 siRNA-2 (sc-44310; Santa Cruz Biotechnology) mixed with transfection reagent (sc-29528; Santa Cruz Biotechnology) were used for transfection according to the manufacturer's instructions.

    Techniques: Migration, Cell Culture, Transfection, Real-time Polymerase Chain Reaction, Western Blot

    Validation of siRNA transfection efficiency and the involvement of integrin β1 in the enhanced invasion of human gastric cancer cells induced by carcinoma-associated fibroblasts (CAFs). (a) Western blot validation of the transfection efficiency of galectin-1 siRNA-1 and siRNA-2 in CAFs. (b) Western blot validation of the transfection efficiency of integrin β1 siRNA-1 and siRNA-2 in gastric cancer cells. (c) Pre-blockade of integrin β1 expression in gastric cancer cells by siRNA-1 and siRNA-2 interrupted the invasion-promoting effect of CAFs that highly express galectin-1. NC, normal control. Magnification, ×200.

    Journal: Cancer Science

    Article Title: Expression of galectin-1 in carcinoma-associated fibroblasts promotes gastric cancer cell invasion through upregulation of integrin β1

    doi: 10.1111/cas.12539

    Figure Lengend Snippet: Validation of siRNA transfection efficiency and the involvement of integrin β1 in the enhanced invasion of human gastric cancer cells induced by carcinoma-associated fibroblasts (CAFs). (a) Western blot validation of the transfection efficiency of galectin-1 siRNA-1 and siRNA-2 in CAFs. (b) Western blot validation of the transfection efficiency of integrin β1 siRNA-1 and siRNA-2 in gastric cancer cells. (c) Pre-blockade of integrin β1 expression in gastric cancer cells by siRNA-1 and siRNA-2 interrupted the invasion-promoting effect of CAFs that highly express galectin-1. NC, normal control. Magnification, ×200.

    Article Snippet: Galectin-1 siRNA-1 (sc-35441; Santa Cruz Biotechnology, Santa Cruz, CA, USA), Gal-1 siRNA-2 (SR302674; OriGene Technologies, Beijing, China), integrin β1 siRNA-1 (sc-35674; Santa Cruz Biotechnology), and integrin β1 siRNA-2 (sc-44310; Santa Cruz Biotechnology) mixed with transfection reagent (sc-29528; Santa Cruz Biotechnology) were used for transfection according to the manufacturer's instructions.

    Techniques: Transfection, Western Blot, Expressing

    Immunohistochemical staining for galectin-1 (a–d) and integrin β1 (e–h) in gastric cancer tissues. Negative (a), weak (b), moderate (c), and strong (d) galectin-1 staining. Negative (e), weak (f), moderate (g), and strong (h) integrin β1staining. Original magnification, ×200.

    Journal: Cancer Science

    Article Title: Expression of galectin-1 in carcinoma-associated fibroblasts promotes gastric cancer cell invasion through upregulation of integrin β1

    doi: 10.1111/cas.12539

    Figure Lengend Snippet: Immunohistochemical staining for galectin-1 (a–d) and integrin β1 (e–h) in gastric cancer tissues. Negative (a), weak (b), moderate (c), and strong (d) galectin-1 staining. Negative (e), weak (f), moderate (g), and strong (h) integrin β1staining. Original magnification, ×200.

    Article Snippet: Galectin-1 siRNA-1 (sc-35441; Santa Cruz Biotechnology, Santa Cruz, CA, USA), Gal-1 siRNA-2 (SR302674; OriGene Technologies, Beijing, China), integrin β1 siRNA-1 (sc-35674; Santa Cruz Biotechnology), and integrin β1 siRNA-2 (sc-44310; Santa Cruz Biotechnology) mixed with transfection reagent (sc-29528; Santa Cruz Biotechnology) were used for transfection according to the manufacturer's instructions.

    Techniques: Immunohistochemical staining, Staining

    Kaplan–Meier survival curves of galectin-1 (Gal-1) and integrin β1 expression in gastric cancer patients. Cumulative 5-year survival rate.

    Journal: Cancer Science

    Article Title: Expression of galectin-1 in carcinoma-associated fibroblasts promotes gastric cancer cell invasion through upregulation of integrin β1

    doi: 10.1111/cas.12539

    Figure Lengend Snippet: Kaplan–Meier survival curves of galectin-1 (Gal-1) and integrin β1 expression in gastric cancer patients. Cumulative 5-year survival rate.

    Article Snippet: Galectin-1 siRNA-1 (sc-35441; Santa Cruz Biotechnology, Santa Cruz, CA, USA), Gal-1 siRNA-2 (SR302674; OriGene Technologies, Beijing, China), integrin β1 siRNA-1 (sc-35674; Santa Cruz Biotechnology), and integrin β1 siRNA-2 (sc-44310; Santa Cruz Biotechnology) mixed with transfection reagent (sc-29528; Santa Cruz Biotechnology) were used for transfection according to the manufacturer's instructions.

    Techniques: Expressing