Journal: Alzheimer's Research & Therapy

Article Title: Association of oxidative stress and inflammatory metabolites with Alzheimer’s disease cerebrospinal fluid biomarkers in mild cognitive impairment

doi: 10.1186/s13195-024-01542-4

Figure Lengend Snippet: Population description

Article Snippet: For AD biomarker analysis on the sample collection day, an aliquot was thawed at room temperature and vortexed for 5–10 s followed by CSF Aβ1-42, t-tau, and p-tau level determination using commercially available enzyme-linked immunosorbent assays, namely Innotest Aβ1-42, Innotest hTAU Ag and Innotest PHOSPHO-TAU (181P) (Innotest, Fujirebio Europe) [ – ].

Techniques:

Journal: Alzheimer's Research & Therapy

Article Title: Association of oxidative stress and inflammatory metabolites with Alzheimer’s disease cerebrospinal fluid biomarkers in mild cognitive impairment

doi: 10.1186/s13195-024-01542-4

Figure Lengend Snippet: Heatmap of meta-analysis results from regression analyses of oxidative stress metabolites with Aβ-42, p-tau, and t-tau levels in Cerebrospinal Fluid (CSF) for the overall sample ( A ). Stratified association results by APOE for Aβ-42 ( B ), p-tau ( C ), and t-tau ( D ) are presented. Note: A star (*) indicates a significant association (False Discovery Rate < 0.05)

Article Snippet: For AD biomarker analysis on the sample collection day, an aliquot was thawed at room temperature and vortexed for 5–10 s followed by CSF Aβ1-42, t-tau, and p-tau level determination using commercially available enzyme-linked immunosorbent assays, namely Innotest Aβ1-42, Innotest hTAU Ag and Innotest PHOSPHO-TAU (181P) (Innotest, Fujirebio Europe) [ – ].

Techniques: