Journal: Scientific Reports

Article Title: A combination approach to treating fungal infections

doi: 10.1038/srep17070

Figure Lengend Snippet: ( A ) Cultures were exposed to C 12 at 8 μg/mL (black inverted triangle), POS at 10 μg/mL (white circle), the combination of C 12 at 2 μg/mL and POS at 2.5 μg/mL (white triangle), and no drug (control, black circle). ( B ) Cultures were exposed to C 14 at 4 μg/mL (black inverted triangle), POS at 10 μg/mL (white circle), and the combination of C 14 at 2 μg/mL and POS at 1.25 μg/mL (white triangle) or C 14 at 2 μg/mL and POS at 2.5 μg/mL (black square), and no drug (control, black circle). Note : inset in panels ( A , B ) After 24 h of no drug/drug exposure, cultures of C. albicans ATCC 64124 (strain B ) were further treated with Alamar Blue dye (25 μg/mL) and incubated at room temperature in the dark for another 10 h. Culture tubes showing red indicates cell survival whereas blue indicates cell death. Lanes a and f = sterility control; b and g = growth control; c and h = POS (10 μg/mL); d, i, and j = POS + AG derivative (concentrations are POS (2.5 μg/mL) + C 12 (2 μg/mL) or POS (1.25 μg/mL) + C 14 (2 μg/mL) or POS (2.5 μg/mL) + C 14 (2 μg/mL)); e and k = AG derivative alone ( C 12 (8 μg/mL) or C 14 (4 μg/mL)).

Article Snippet: C 14 (500 or 700 μg/mL), POS (100 μg/mL), and ITC (150 μg/mL) alone, when applied on disk, did not show a zone of inhibition against C. albicans ATCC 64124 ( B ).

Techniques: Incubation, Sterility

Journal: Scientific Reports

Article Title: Antimicrobial efficacy of Mentha piperata -derived biogenic zinc oxide nanoparticles against UTI-resistant pathogens

doi: 10.1038/s41598-023-41502-w

Figure Lengend Snippet: Pictorial presentation of bacterial and fungal growth inhibition by ZnO nanoparticles ( a ) effect of different concentrations of ZnO NPs against resistant Pseudomonas aeroginosa ( b ) Candida albicans ( c ) Proteus mirabilis ( d ) ciprofloxacin against Pseudomonas aeruginosa ( e ) clotrimazole against Candida albicans and ( f ) azithromycin against Proteus mirabilis.

Article Snippet: The ciprofloxacin displayed a 45 mm zone of inhibition against Pseudomonas aeruginosa (ATCC # 9721), clotrimazole exhibited a 23 mm zone of inhibition against Candida albicans (ATCC # 14,054) and azithromycin displayed 35 mm zone of inhibition against Proteus Mirabilis (ATCC # 12453).

Techniques: Inhibition

Journal: Infection and Drug Resistance

Article Title: Optimized Production of the Allylamine Antifungal “Terbinafine” by Lysinibacillus Isolate MK212927 Using Response Surface Methodology

doi: 10.2147/IDR.S267590

Figure Lengend Snippet: Standard calibration curve of terbinafine concentration versus inhibition zones obtained against Candida albicans ATCC 10231.

Article Snippet: The diameters of inhibition zones against Candida albicans ATCC 10231 were determined after 24 hours of incubation at 28°C.

Techniques: Concentration Assay, Inhibition

Journal: Infection and Drug Resistance

Article Title: Optimized Production of the Allylamine Antifungal “Terbinafine” by Lysinibacillus Isolate MK212927 Using Response Surface Methodology

doi: 10.2147/IDR.S267590

Figure Lengend Snippet: Effect of ( A ) different Carbon sources and ( B ) Nitrogen sources on the antifungal activity of Lysinibacillus isolate MK212927 against Candida albicans ATCC 10231.

Article Snippet: The diameters of inhibition zones against Candida albicans ATCC 10231 were determined after 24 hours of incubation at 28°C.

Techniques: Activity Assay

Journal: Scientific Reports

Article Title: Isolation, characterization and antifungal docking studies of wortmannin isolated from Penicillium radicum

doi: 10.1038/srep11948

Figure Lengend Snippet: Antifungal activity of Wtmn isolated from Penicillium radicum MTCC 7584.

Article Snippet: Fermented broth from PDB showed maximum zone of inhibition against Candida albicans ATCC 24433 and considered as the most suitable medium for metabolite production (data not shown), and used as the production medium for further studies.

Techniques: Activity Assay, Isolation