idk zonulin elisa kit  (Immundiagnostik AG)


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    Immundiagnostik AG idk zonulin elisa kit
    Calprotectin and <t>zonulin</t> levels in the serum of individuals at risk of RA, new onset rheumatic patients and chronic RA patients. (A) Serum calprotectin levels in seronegative, symptom-free first-degree relatives (FDR 1, n=42), individuals with RA specific autoantibodies (FDR 2, n=40), individuals with RA specific symptoms (FDR 3, n=38) and chronic RA patients (cRA, n=45), recruited via the SCREEN-RA and SCQM cohort. (B) Serum calprotectin levels in healthy blood donors (BD, n=20), and patients newly diagnosed with non-rheumatic disease (NRD, n=35), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=50), axial spondyloarthritis (axSpA, n=30) and reactive arthritis (ReA, n=10), recruited via the Rheuma-VOR cohort. (C) Serum C-reactive protein (CRP) levels in NRD (n=34), RA (n=33), PsA (n=50) and axSpA (n=28) patients from the Rheuma-VOR cohort. (D) Spearman correlation between serum CRP and serum calprotectin measured in patients from the Rheuma-VOR cohort. (E) Serum calprotectin levels in FDR individuals and cRA patients from the SCREEN-RA/SCQM cohort and RA patients from the Rheuma-VOR cohort divided by RF and ACPA positivity. Statistical differences between positive and negative groups within patient groups were calculated using Mann-Whitney test. (F) Serum CRP levels in RA patients from the Rheuma-VOR cohort divided by RF and ACPA pre- and absence. Statistical differences between groups were calculated using Mann-Whitney test. (G) Serum zonulin levels in healthy blood donors (BD, n=20), patients newly diagnosed with non-rheumatic disease (NRD, n=22), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=48), axial spondyloarthritis (axSpA, n=30), reactive arthritis (ReA, n=10), as well as IBD patients with active ulcerative colitis (UC A, n=14), active Crohn’s disease (CD A, n=13), and Crohn’s disease under remission (CD R, n=12). Dots in the Rheuma-VOR groups depict single measurements, while dots in the IBD groups represent median values calculated from 2 replicates. (H) Serum zonulin in Rheuma-VOR RA patients clustered by RF and ACPA positivity. Statistical differences between groups were calculated using Mann-Whitney test. Data is shown as mean ± SD, *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; not significant if not further indicated.
    Idk Zonulin Elisa Kit, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/idk zonulin elisa kit/product/Immundiagnostik AG
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    idk zonulin elisa kit - by Bioz Stars, 2023-09
    94/100 stars

    Images

    1) Product Images from "Characterization of serum biomarkers and antibody responses against Prevotella spp. in preclinical and new-onset phase of rheumatic diseases"

    Article Title: Characterization of serum biomarkers and antibody responses against Prevotella spp. in preclinical and new-onset phase of rheumatic diseases

    Journal: Frontiers in Cellular and Infection Microbiology

    doi: 10.3389/fcimb.2022.1096211

    Calprotectin and zonulin levels in the serum of individuals at risk of RA, new onset rheumatic patients and chronic RA patients. (A) Serum calprotectin levels in seronegative, symptom-free first-degree relatives (FDR 1, n=42), individuals with RA specific autoantibodies (FDR 2, n=40), individuals with RA specific symptoms (FDR 3, n=38) and chronic RA patients (cRA, n=45), recruited via the SCREEN-RA and SCQM cohort. (B) Serum calprotectin levels in healthy blood donors (BD, n=20), and patients newly diagnosed with non-rheumatic disease (NRD, n=35), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=50), axial spondyloarthritis (axSpA, n=30) and reactive arthritis (ReA, n=10), recruited via the Rheuma-VOR cohort. (C) Serum C-reactive protein (CRP) levels in NRD (n=34), RA (n=33), PsA (n=50) and axSpA (n=28) patients from the Rheuma-VOR cohort. (D) Spearman correlation between serum CRP and serum calprotectin measured in patients from the Rheuma-VOR cohort. (E) Serum calprotectin levels in FDR individuals and cRA patients from the SCREEN-RA/SCQM cohort and RA patients from the Rheuma-VOR cohort divided by RF and ACPA positivity. Statistical differences between positive and negative groups within patient groups were calculated using Mann-Whitney test. (F) Serum CRP levels in RA patients from the Rheuma-VOR cohort divided by RF and ACPA pre- and absence. Statistical differences between groups were calculated using Mann-Whitney test. (G) Serum zonulin levels in healthy blood donors (BD, n=20), patients newly diagnosed with non-rheumatic disease (NRD, n=22), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=48), axial spondyloarthritis (axSpA, n=30), reactive arthritis (ReA, n=10), as well as IBD patients with active ulcerative colitis (UC A, n=14), active Crohn’s disease (CD A, n=13), and Crohn’s disease under remission (CD R, n=12). Dots in the Rheuma-VOR groups depict single measurements, while dots in the IBD groups represent median values calculated from 2 replicates. (H) Serum zonulin in Rheuma-VOR RA patients clustered by RF and ACPA positivity. Statistical differences between groups were calculated using Mann-Whitney test. Data is shown as mean ± SD, *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; not significant if not further indicated.
    Figure Legend Snippet: Calprotectin and zonulin levels in the serum of individuals at risk of RA, new onset rheumatic patients and chronic RA patients. (A) Serum calprotectin levels in seronegative, symptom-free first-degree relatives (FDR 1, n=42), individuals with RA specific autoantibodies (FDR 2, n=40), individuals with RA specific symptoms (FDR 3, n=38) and chronic RA patients (cRA, n=45), recruited via the SCREEN-RA and SCQM cohort. (B) Serum calprotectin levels in healthy blood donors (BD, n=20), and patients newly diagnosed with non-rheumatic disease (NRD, n=35), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=50), axial spondyloarthritis (axSpA, n=30) and reactive arthritis (ReA, n=10), recruited via the Rheuma-VOR cohort. (C) Serum C-reactive protein (CRP) levels in NRD (n=34), RA (n=33), PsA (n=50) and axSpA (n=28) patients from the Rheuma-VOR cohort. (D) Spearman correlation between serum CRP and serum calprotectin measured in patients from the Rheuma-VOR cohort. (E) Serum calprotectin levels in FDR individuals and cRA patients from the SCREEN-RA/SCQM cohort and RA patients from the Rheuma-VOR cohort divided by RF and ACPA positivity. Statistical differences between positive and negative groups within patient groups were calculated using Mann-Whitney test. (F) Serum CRP levels in RA patients from the Rheuma-VOR cohort divided by RF and ACPA pre- and absence. Statistical differences between groups were calculated using Mann-Whitney test. (G) Serum zonulin levels in healthy blood donors (BD, n=20), patients newly diagnosed with non-rheumatic disease (NRD, n=22), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=48), axial spondyloarthritis (axSpA, n=30), reactive arthritis (ReA, n=10), as well as IBD patients with active ulcerative colitis (UC A, n=14), active Crohn’s disease (CD A, n=13), and Crohn’s disease under remission (CD R, n=12). Dots in the Rheuma-VOR groups depict single measurements, while dots in the IBD groups represent median values calculated from 2 replicates. (H) Serum zonulin in Rheuma-VOR RA patients clustered by RF and ACPA positivity. Statistical differences between groups were calculated using Mann-Whitney test. Data is shown as mean ± SD, *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; not significant if not further indicated.

    Techniques Used: MANN-WHITNEY

    idk zonulin stool elisa kits  (Immundiagnostik AG)


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    Immundiagnostik AG idk zonulin stool elisa kits
    Idk Zonulin Stool Elisa Kits, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 86 stars, based on 1 article reviews
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    idk zonulin stool elisa kits - by Bioz Stars, 2023-09
    86/100 stars

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    idk zonulin elisa kit  (Immundiagnostik AG)


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    Immundiagnostik AG idk zonulin elisa kit
    Calprotectin and <t>zonulin</t> levels in the serum of individuals at risk of RA, new onset rheumatic patients and chronic RA patients. (A) Serum calprotectin levels in seronegative, symptom-free first-degree relatives (FDR 1, n=42), individuals with RA specific autoantibodies (FDR 2, n=40), individuals with RA specific symptoms (FDR 3, n=38) and chronic RA patients (cRA, n=45), recruited via the SCREEN-RA and SCQM cohort. (B) Serum calprotectin levels in healthy blood donors (BD, n=20), and patients newly diagnosed with non-rheumatic disease (NRD, n=35), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=50), axial spondyloarthritis (axSpA, n=30) and reactive arthritis (ReA, n=10), recruited via the Rheuma-VOR cohort. (C) Serum C-reactive protein (CRP) levels in NRD (n=34), RA (n=33), PsA (n=50) and axSpA (n=28) patients from the Rheuma-VOR cohort. (D) Spearman correlation between serum CRP and serum calprotectin measured in patients from the Rheuma-VOR cohort. (E) Serum calprotectin levels in FDR individuals and cRA patients from the SCREEN-RA/SCQM cohort and RA patients from the Rheuma-VOR cohort divided by RF and ACPA positivity. Statistical differences between positive and negative groups within patient groups were calculated using Mann-Whitney test. (F) Serum CRP levels in RA patients from the Rheuma-VOR cohort divided by RF and ACPA pre- and absence. Statistical differences between groups were calculated using Mann-Whitney test. (G) Serum zonulin levels in healthy blood donors (BD, n=20), patients newly diagnosed with non-rheumatic disease (NRD, n=22), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=48), axial spondyloarthritis (axSpA, n=30), reactive arthritis (ReA, n=10), as well as IBD patients with active ulcerative colitis (UC A, n=14), active Crohn’s disease (CD A, n=13), and Crohn’s disease under remission (CD R, n=12). Dots in the Rheuma-VOR groups depict single measurements, while dots in the IBD groups represent median values calculated from 2 replicates. (H) Serum zonulin in Rheuma-VOR RA patients clustered by RF and ACPA positivity. Statistical differences between groups were calculated using Mann-Whitney test. Data is shown as mean ± SD, *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; not significant if not further indicated.
    Idk Zonulin Elisa Kit, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/idk zonulin elisa kit/product/Immundiagnostik AG
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    idk zonulin elisa kit - by Bioz Stars, 2023-09
    94/100 stars

    Images

    1) Product Images from "Characterization of serum biomarkers and antibody responses against Prevotella spp. in preclinical and new-onset phase of rheumatic diseases"

    Article Title: Characterization of serum biomarkers and antibody responses against Prevotella spp. in preclinical and new-onset phase of rheumatic diseases

    Journal: Frontiers in Cellular and Infection Microbiology

    doi: 10.3389/fcimb.2022.1096211

    Calprotectin and zonulin levels in the serum of individuals at risk of RA, new onset rheumatic patients and chronic RA patients. (A) Serum calprotectin levels in seronegative, symptom-free first-degree relatives (FDR 1, n=42), individuals with RA specific autoantibodies (FDR 2, n=40), individuals with RA specific symptoms (FDR 3, n=38) and chronic RA patients (cRA, n=45), recruited via the SCREEN-RA and SCQM cohort. (B) Serum calprotectin levels in healthy blood donors (BD, n=20), and patients newly diagnosed with non-rheumatic disease (NRD, n=35), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=50), axial spondyloarthritis (axSpA, n=30) and reactive arthritis (ReA, n=10), recruited via the Rheuma-VOR cohort. (C) Serum C-reactive protein (CRP) levels in NRD (n=34), RA (n=33), PsA (n=50) and axSpA (n=28) patients from the Rheuma-VOR cohort. (D) Spearman correlation between serum CRP and serum calprotectin measured in patients from the Rheuma-VOR cohort. (E) Serum calprotectin levels in FDR individuals and cRA patients from the SCREEN-RA/SCQM cohort and RA patients from the Rheuma-VOR cohort divided by RF and ACPA positivity. Statistical differences between positive and negative groups within patient groups were calculated using Mann-Whitney test. (F) Serum CRP levels in RA patients from the Rheuma-VOR cohort divided by RF and ACPA pre- and absence. Statistical differences between groups were calculated using Mann-Whitney test. (G) Serum zonulin levels in healthy blood donors (BD, n=20), patients newly diagnosed with non-rheumatic disease (NRD, n=22), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=48), axial spondyloarthritis (axSpA, n=30), reactive arthritis (ReA, n=10), as well as IBD patients with active ulcerative colitis (UC A, n=14), active Crohn’s disease (CD A, n=13), and Crohn’s disease under remission (CD R, n=12). Dots in the Rheuma-VOR groups depict single measurements, while dots in the IBD groups represent median values calculated from 2 replicates. (H) Serum zonulin in Rheuma-VOR RA patients clustered by RF and ACPA positivity. Statistical differences between groups were calculated using Mann-Whitney test. Data is shown as mean ± SD, *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; not significant if not further indicated.
    Figure Legend Snippet: Calprotectin and zonulin levels in the serum of individuals at risk of RA, new onset rheumatic patients and chronic RA patients. (A) Serum calprotectin levels in seronegative, symptom-free first-degree relatives (FDR 1, n=42), individuals with RA specific autoantibodies (FDR 2, n=40), individuals with RA specific symptoms (FDR 3, n=38) and chronic RA patients (cRA, n=45), recruited via the SCREEN-RA and SCQM cohort. (B) Serum calprotectin levels in healthy blood donors (BD, n=20), and patients newly diagnosed with non-rheumatic disease (NRD, n=35), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=50), axial spondyloarthritis (axSpA, n=30) and reactive arthritis (ReA, n=10), recruited via the Rheuma-VOR cohort. (C) Serum C-reactive protein (CRP) levels in NRD (n=34), RA (n=33), PsA (n=50) and axSpA (n=28) patients from the Rheuma-VOR cohort. (D) Spearman correlation between serum CRP and serum calprotectin measured in patients from the Rheuma-VOR cohort. (E) Serum calprotectin levels in FDR individuals and cRA patients from the SCREEN-RA/SCQM cohort and RA patients from the Rheuma-VOR cohort divided by RF and ACPA positivity. Statistical differences between positive and negative groups within patient groups were calculated using Mann-Whitney test. (F) Serum CRP levels in RA patients from the Rheuma-VOR cohort divided by RF and ACPA pre- and absence. Statistical differences between groups were calculated using Mann-Whitney test. (G) Serum zonulin levels in healthy blood donors (BD, n=20), patients newly diagnosed with non-rheumatic disease (NRD, n=22), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=48), axial spondyloarthritis (axSpA, n=30), reactive arthritis (ReA, n=10), as well as IBD patients with active ulcerative colitis (UC A, n=14), active Crohn’s disease (CD A, n=13), and Crohn’s disease under remission (CD R, n=12). Dots in the Rheuma-VOR groups depict single measurements, while dots in the IBD groups represent median values calculated from 2 replicates. (H) Serum zonulin in Rheuma-VOR RA patients clustered by RF and ACPA positivity. Statistical differences between groups were calculated using Mann-Whitney test. Data is shown as mean ± SD, *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; not significant if not further indicated.

    Techniques Used: MANN-WHITNEY

    idk zonulin elisa kit  (Immundiagnostik AG)


    Bioz Verified Symbol Immundiagnostik AG is a verified supplier
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    Immundiagnostik AG idk zonulin elisa kit
    Idk Zonulin Elisa Kit, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/idk zonulin elisa kit/product/Immundiagnostik AG
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    idk zonulin elisa kit - by Bioz Stars, 2023-09
    86/100 stars

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    idk zonulin elisa kit  (Immundiagnostik AG)


    Bioz Verified Symbol Immundiagnostik AG is a verified supplier
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    Immundiagnostik AG idk zonulin elisa kit
    Study flow chart. CAL—calprotectin; <t>ZON—zonulin;</t> sIgA—secretory immunoglobulin A; n —number of studied cases.
    Idk Zonulin Elisa Kit, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/idk zonulin elisa kit/product/Immundiagnostik AG
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    idk zonulin elisa kit - by Bioz Stars, 2023-09
    94/100 stars

    Images

    1) Product Images from "Impact of Biometric Patient Data, Probiotic Supplementation, and Selected Gut Microorganisms on Calprotectin, Zonulin, and sIgA Concentrations in the Stool of Adults Aged 18–74 Years"

    Article Title: Impact of Biometric Patient Data, Probiotic Supplementation, and Selected Gut Microorganisms on Calprotectin, Zonulin, and sIgA Concentrations in the Stool of Adults Aged 18–74 Years

    Journal: Biomolecules

    doi: 10.3390/biom12121781

    Study flow chart. CAL—calprotectin; ZON—zonulin; sIgA—secretory immunoglobulin A; n —number of studied cases.
    Figure Legend Snippet: Study flow chart. CAL—calprotectin; ZON—zonulin; sIgA—secretory immunoglobulin A; n —number of studied cases.

    Techniques Used:

    Reference ranges for biomarkers, interpretation, and detection limits.
    Figure Legend Snippet: Reference ranges for biomarkers, interpretation, and detection limits.

    Techniques Used:

    The calprotectin, zonulin, and sIgA data from patients with reference range. Designation: green—normal level; yellow—subnormal or gray-zone; red—elevated level.
    Figure Legend Snippet: The calprotectin, zonulin, and sIgA data from patients with reference range. Designation: green—normal level; yellow—subnormal or gray-zone; red—elevated level.

    Techniques Used:

    Stool calprotectin, zonulin, and sIgA levels (log transformed) in participants distinguished by probiotic supplementation with biomarkers reference range. Designation: green—normal level; yellow—subnormal or gray-zone; red—elevated level; * p < 0.05.
    Figure Legend Snippet: Stool calprotectin, zonulin, and sIgA levels (log transformed) in participants distinguished by probiotic supplementation with biomarkers reference range. Designation: green—normal level; yellow—subnormal or gray-zone; red—elevated level; * p < 0.05.

    Techniques Used: Transformation Assay

    Stool calprotectin, zonulin, and sIgA level (log transformed) in participants distinguished by age intervals with biomarkers reference range. Designation: green—normal level; yellow—subnormal or gray-zone; red—elevated level; * p < 0.05; (*) p = 0.1–0.05.
    Figure Legend Snippet: Stool calprotectin, zonulin, and sIgA level (log transformed) in participants distinguished by age intervals with biomarkers reference range. Designation: green—normal level; yellow—subnormal or gray-zone; red—elevated level; * p < 0.05; (*) p = 0.1–0.05.

    Techniques Used: Transformation Assay

    Linkage distances between analyzed biomarkers and analyzed microorganisms. The length of each line represents the strength of the correlation coefficient ( A ). In the case of the circle diameter of microorganisms, the circle size represents the mean level. The biomarker circle size was not scaled. Significant correlations of analyzed biomarkers and microorganism species ( B ) and correlation between logarithmic transformed biomarker levels ( C ). CAL—calprotectin; sIgA—secretory immunoglobulin A; ZON—zonulin; TBC—total bacteria count; NLF—non-lactose fermenting; Log CFU—logarithmic transformed colony-forming units.
    Figure Legend Snippet: Linkage distances between analyzed biomarkers and analyzed microorganisms. The length of each line represents the strength of the correlation coefficient ( A ). In the case of the circle diameter of microorganisms, the circle size represents the mean level. The biomarker circle size was not scaled. Significant correlations of analyzed biomarkers and microorganism species ( B ) and correlation between logarithmic transformed biomarker levels ( C ). CAL—calprotectin; sIgA—secretory immunoglobulin A; ZON—zonulin; TBC—total bacteria count; NLF—non-lactose fermenting; Log CFU—logarithmic transformed colony-forming units.

    Techniques Used: Biomarker Assay, Transformation Assay

    Linkage distances between analyzed biomarkers and selected microorganisms in groups distinguished according to probiotics usage ( A ). The length of each line represents the strength of the correlation coefficient. In the case of the circle diameter of microorganisms, the circle size represents the mean level. The biomarker circle size was not scaled. Significant correlations of analyzed biomarkers and microorganism species ( B ) and correlation between logarithmic transformed biomarkers’ levels ( C ). CAL—calprotectin; sIgA—secretory immunoglobulin A; ZON—zonulin; TBC—total bacteria count; NLF—non-lactose fermenting; Log CFU—logarithmic transformed colony-forming units.
    Figure Legend Snippet: Linkage distances between analyzed biomarkers and selected microorganisms in groups distinguished according to probiotics usage ( A ). The length of each line represents the strength of the correlation coefficient. In the case of the circle diameter of microorganisms, the circle size represents the mean level. The biomarker circle size was not scaled. Significant correlations of analyzed biomarkers and microorganism species ( B ) and correlation between logarithmic transformed biomarkers’ levels ( C ). CAL—calprotectin; sIgA—secretory immunoglobulin A; ZON—zonulin; TBC—total bacteria count; NLF—non-lactose fermenting; Log CFU—logarithmic transformed colony-forming units.

    Techniques Used: Biomarker Assay, Transformation Assay

    idk zonulin elisa kit  (Immundiagnostik AG)


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    Immundiagnostik AG idk zonulin elisa kit
    Idk Zonulin Elisa Kit, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/idk zonulin elisa kit/product/Immundiagnostik AG
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    idk zonulin elisa kit - by Bioz Stars, 2023-09
    94/100 stars

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    idk zonulin elisa kit  (Immundiagnostik AG)


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    Immundiagnostik AG idk zonulin elisa kit
    Demographic and anthropometrical characteristics of older volunteers recruited for the study.
    Idk Zonulin Elisa Kit, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/idk zonulin elisa kit/product/Immundiagnostik AG
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    idk zonulin elisa kit - by Bioz Stars, 2023-09
    94/100 stars

    Images

    1) Product Images from "Bacterial DNAemia is associated with serum zonulin levels in older subjects"

    Article Title: Bacterial DNAemia is associated with serum zonulin levels in older subjects

    Journal: Scientific Reports

    doi: 10.1038/s41598-021-90476-0

    Demographic and anthropometrical characteristics of older volunteers recruited for the study.
    Figure Legend Snippet: Demographic and anthropometrical characteristics of older volunteers recruited for the study.

    Techniques Used:

    Linear regression and correlation analysis carried out between blood bacterial load and serum zonulin levels. Correlation has been assessed through Pearson’s ( r coefficient), Spearman’s (ρ), and Kendall’s (τ) analyses. Analyses were performed on the first (n = 43, panels A , B,C ) and the second (n = 42, panel D , E,F ) set of blood samples collected from older people. The second set of blood samples was collected approximately four months after the first draw from the same older volunteers. Panels A and D, tables showing correlation and regression indexes and p values. Panels B and E, linear regression plot; vertical dotted lines indicate the quartiles. Panels C and F, Tukey box plots showing levels of bacterial DNAema in blood samples grouped in quartiles based on zonulin level.
    Figure Legend Snippet: Linear regression and correlation analysis carried out between blood bacterial load and serum zonulin levels. Correlation has been assessed through Pearson’s ( r coefficient), Spearman’s (ρ), and Kendall’s (τ) analyses. Analyses were performed on the first (n = 43, panels A , B,C ) and the second (n = 42, panel D , E,F ) set of blood samples collected from older people. The second set of blood samples was collected approximately four months after the first draw from the same older volunteers. Panels A and D, tables showing correlation and regression indexes and p values. Panels B and E, linear regression plot; vertical dotted lines indicate the quartiles. Panels C and F, Tukey box plots showing levels of bacterial DNAema in blood samples grouped in quartiles based on zonulin level.

    Techniques Used:

    idk zonulin elisa kit  (Immundiagnostik AG)


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    Immundiagnostik AG idk zonulin elisa kit
    The pre- and post-run values of C-reactive protein and intestinal permeability biomarkers (n = 10).
    Idk Zonulin Elisa Kit, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/idk zonulin elisa kit/product/Immundiagnostik AG
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    idk zonulin elisa kit - by Bioz Stars, 2023-09
    94/100 stars

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    1) Product Images from "Strenuous 12-h run elevates circulating biomarkers of oxidative stress, inflammation and intestinal permeability in middle-aged amateur runners: A preliminary study"

    Article Title: Strenuous 12-h run elevates circulating biomarkers of oxidative stress, inflammation and intestinal permeability in middle-aged amateur runners: A preliminary study

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0249183

    The pre- and post-run values of C-reactive protein and intestinal permeability biomarkers (n = 10).
    Figure Legend Snippet: The pre- and post-run values of C-reactive protein and intestinal permeability biomarkers (n = 10).

    Techniques Used: Permeability

    idk zonulin elisa kit  (Immundiagnostik AG)


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    Immundiagnostik AG idk zonulin elisa kit
    Idk Zonulin Elisa Kit, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/idk zonulin elisa kit/product/Immundiagnostik AG
    Average 94 stars, based on 1 article reviews
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    idk zonulin elisa kit  (Immundiagnostik AG)


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    Immundiagnostik AG idk zonulin elisa kit
    Linear regression and correlation analysis carried out between blood bacterial load and serum <t>zonulin</t> levels. Correlation has been assessed through Pearson’s (r coefficient), Spearman’s (ρ), and Kendall’s (τ) analyses.
    Idk Zonulin Elisa Kit, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 94 stars, based on 1 article reviews
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    94/100 stars

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    1) Product Images from "Bacterial DNAemia is associated with serum zonulin levels in older subjects"

    Article Title: Bacterial DNAemia is associated with serum zonulin levels in older subjects

    Journal: bioRxiv

    doi: 10.1101/2020.04.10.035519

    Linear regression and correlation analysis carried out between blood bacterial load and serum zonulin levels. Correlation has been assessed through Pearson’s (r coefficient), Spearman’s (ρ), and Kendall’s (τ) analyses.
    Figure Legend Snippet: Linear regression and correlation analysis carried out between blood bacterial load and serum zonulin levels. Correlation has been assessed through Pearson’s (r coefficient), Spearman’s (ρ), and Kendall’s (τ) analyses.

    Techniques Used:

    idk zonulin elisa kit  (Immundiagnostik AG)


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    Immundiagnostik AG idk zonulin elisa kit
    <t> Zonulin </t> levels in stool at baseline (ng/ml) and after each intervention
    Idk Zonulin Elisa Kit, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    idk zonulin elisa kit - by Bioz Stars, 2023-09
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    1) Product Images from "Cofactors of wheat-dependent exercise-induced anaphylaxis do not increase highly individual gliadin absorption in healthy volunteers"

    Article Title: Cofactors of wheat-dependent exercise-induced anaphylaxis do not increase highly individual gliadin absorption in healthy volunteers

    Journal: Clinical and Translational Allergy

    doi: 10.1186/s13601-019-0260-0

     Zonulin  levels in stool at baseline (ng/ml) and after each intervention
    Figure Legend Snippet: Zonulin levels in stool at baseline (ng/ml) and after each intervention

    Techniques Used:

    Microbiota composition and diversity after interventions and according to stool zonulin levels. Redundancy discriminant analysis (RDA) to divide probands into groups according to high or low zonulin group and intervention over all samples ( a ), Discriminant analysis of principal components (DAPC) plot ( b ), alpha diversity according to high or low zonulin group and intervention over all samples, Shannon index ( c ) and Chao1 ( d ), linear discriminant analysis (LDA) combined with effect size measurements (LeFSe) revealed specific bacterial groups at OTU level related to the low zonulin level group at baseline ( e ) and after gluten intervention ( f ). 0, baseline, 1, after intervention with gluten, 2–6, after intervention with gluten and different cofactors, 2, proton pump inhibitor, 3, acetyl salicylic acid, 4, alcohol, 5, aerobic exercise, 6, anaerobic exercise, OTU operational taxonomic unit
    Figure Legend Snippet: Microbiota composition and diversity after interventions and according to stool zonulin levels. Redundancy discriminant analysis (RDA) to divide probands into groups according to high or low zonulin group and intervention over all samples ( a ), Discriminant analysis of principal components (DAPC) plot ( b ), alpha diversity according to high or low zonulin group and intervention over all samples, Shannon index ( c ) and Chao1 ( d ), linear discriminant analysis (LDA) combined with effect size measurements (LeFSe) revealed specific bacterial groups at OTU level related to the low zonulin level group at baseline ( e ) and after gluten intervention ( f ). 0, baseline, 1, after intervention with gluten, 2–6, after intervention with gluten and different cofactors, 2, proton pump inhibitor, 3, acetyl salicylic acid, 4, alcohol, 5, aerobic exercise, 6, anaerobic exercise, OTU operational taxonomic unit

    Techniques Used:

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    Immundiagnostik AG idk zonulin elisa kit
    Calprotectin and <t>zonulin</t> levels in the serum of individuals at risk of RA, new onset rheumatic patients and chronic RA patients. (A) Serum calprotectin levels in seronegative, symptom-free first-degree relatives (FDR 1, n=42), individuals with RA specific autoantibodies (FDR 2, n=40), individuals with RA specific symptoms (FDR 3, n=38) and chronic RA patients (cRA, n=45), recruited via the SCREEN-RA and SCQM cohort. (B) Serum calprotectin levels in healthy blood donors (BD, n=20), and patients newly diagnosed with non-rheumatic disease (NRD, n=35), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=50), axial spondyloarthritis (axSpA, n=30) and reactive arthritis (ReA, n=10), recruited via the Rheuma-VOR cohort. (C) Serum C-reactive protein (CRP) levels in NRD (n=34), RA (n=33), PsA (n=50) and axSpA (n=28) patients from the Rheuma-VOR cohort. (D) Spearman correlation between serum CRP and serum calprotectin measured in patients from the Rheuma-VOR cohort. (E) Serum calprotectin levels in FDR individuals and cRA patients from the SCREEN-RA/SCQM cohort and RA patients from the Rheuma-VOR cohort divided by RF and ACPA positivity. Statistical differences between positive and negative groups within patient groups were calculated using Mann-Whitney test. (F) Serum CRP levels in RA patients from the Rheuma-VOR cohort divided by RF and ACPA pre- and absence. Statistical differences between groups were calculated using Mann-Whitney test. (G) Serum zonulin levels in healthy blood donors (BD, n=20), patients newly diagnosed with non-rheumatic disease (NRD, n=22), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=48), axial spondyloarthritis (axSpA, n=30), reactive arthritis (ReA, n=10), as well as IBD patients with active ulcerative colitis (UC A, n=14), active Crohn’s disease (CD A, n=13), and Crohn’s disease under remission (CD R, n=12). Dots in the Rheuma-VOR groups depict single measurements, while dots in the IBD groups represent median values calculated from 2 replicates. (H) Serum zonulin in Rheuma-VOR RA patients clustered by RF and ACPA positivity. Statistical differences between groups were calculated using Mann-Whitney test. Data is shown as mean ± SD, *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; not significant if not further indicated.
    Idk Zonulin Elisa Kit, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Immundiagnostik AG idk zonulin stool elisa kits
    Calprotectin and <t>zonulin</t> levels in the serum of individuals at risk of RA, new onset rheumatic patients and chronic RA patients. (A) Serum calprotectin levels in seronegative, symptom-free first-degree relatives (FDR 1, n=42), individuals with RA specific autoantibodies (FDR 2, n=40), individuals with RA specific symptoms (FDR 3, n=38) and chronic RA patients (cRA, n=45), recruited via the SCREEN-RA and SCQM cohort. (B) Serum calprotectin levels in healthy blood donors (BD, n=20), and patients newly diagnosed with non-rheumatic disease (NRD, n=35), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=50), axial spondyloarthritis (axSpA, n=30) and reactive arthritis (ReA, n=10), recruited via the Rheuma-VOR cohort. (C) Serum C-reactive protein (CRP) levels in NRD (n=34), RA (n=33), PsA (n=50) and axSpA (n=28) patients from the Rheuma-VOR cohort. (D) Spearman correlation between serum CRP and serum calprotectin measured in patients from the Rheuma-VOR cohort. (E) Serum calprotectin levels in FDR individuals and cRA patients from the SCREEN-RA/SCQM cohort and RA patients from the Rheuma-VOR cohort divided by RF and ACPA positivity. Statistical differences between positive and negative groups within patient groups were calculated using Mann-Whitney test. (F) Serum CRP levels in RA patients from the Rheuma-VOR cohort divided by RF and ACPA pre- and absence. Statistical differences between groups were calculated using Mann-Whitney test. (G) Serum zonulin levels in healthy blood donors (BD, n=20), patients newly diagnosed with non-rheumatic disease (NRD, n=22), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=48), axial spondyloarthritis (axSpA, n=30), reactive arthritis (ReA, n=10), as well as IBD patients with active ulcerative colitis (UC A, n=14), active Crohn’s disease (CD A, n=13), and Crohn’s disease under remission (CD R, n=12). Dots in the Rheuma-VOR groups depict single measurements, while dots in the IBD groups represent median values calculated from 2 replicates. (H) Serum zonulin in Rheuma-VOR RA patients clustered by RF and ACPA positivity. Statistical differences between groups were calculated using Mann-Whitney test. Data is shown as mean ± SD, *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; not significant if not further indicated.
    Idk Zonulin Stool Elisa Kits, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Calprotectin and zonulin levels in the serum of individuals at risk of RA, new onset rheumatic patients and chronic RA patients. (A) Serum calprotectin levels in seronegative, symptom-free first-degree relatives (FDR 1, n=42), individuals with RA specific autoantibodies (FDR 2, n=40), individuals with RA specific symptoms (FDR 3, n=38) and chronic RA patients (cRA, n=45), recruited via the SCREEN-RA and SCQM cohort. (B) Serum calprotectin levels in healthy blood donors (BD, n=20), and patients newly diagnosed with non-rheumatic disease (NRD, n=35), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=50), axial spondyloarthritis (axSpA, n=30) and reactive arthritis (ReA, n=10), recruited via the Rheuma-VOR cohort. (C) Serum C-reactive protein (CRP) levels in NRD (n=34), RA (n=33), PsA (n=50) and axSpA (n=28) patients from the Rheuma-VOR cohort. (D) Spearman correlation between serum CRP and serum calprotectin measured in patients from the Rheuma-VOR cohort. (E) Serum calprotectin levels in FDR individuals and cRA patients from the SCREEN-RA/SCQM cohort and RA patients from the Rheuma-VOR cohort divided by RF and ACPA positivity. Statistical differences between positive and negative groups within patient groups were calculated using Mann-Whitney test. (F) Serum CRP levels in RA patients from the Rheuma-VOR cohort divided by RF and ACPA pre- and absence. Statistical differences between groups were calculated using Mann-Whitney test. (G) Serum zonulin levels in healthy blood donors (BD, n=20), patients newly diagnosed with non-rheumatic disease (NRD, n=22), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=48), axial spondyloarthritis (axSpA, n=30), reactive arthritis (ReA, n=10), as well as IBD patients with active ulcerative colitis (UC A, n=14), active Crohn’s disease (CD A, n=13), and Crohn’s disease under remission (CD R, n=12). Dots in the Rheuma-VOR groups depict single measurements, while dots in the IBD groups represent median values calculated from 2 replicates. (H) Serum zonulin in Rheuma-VOR RA patients clustered by RF and ACPA positivity. Statistical differences between groups were calculated using Mann-Whitney test. Data is shown as mean ± SD, *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; not significant if not further indicated.

    Journal: Frontiers in Cellular and Infection Microbiology

    Article Title: Characterization of serum biomarkers and antibody responses against Prevotella spp. in preclinical and new-onset phase of rheumatic diseases

    doi: 10.3389/fcimb.2022.1096211

    Figure Lengend Snippet: Calprotectin and zonulin levels in the serum of individuals at risk of RA, new onset rheumatic patients and chronic RA patients. (A) Serum calprotectin levels in seronegative, symptom-free first-degree relatives (FDR 1, n=42), individuals with RA specific autoantibodies (FDR 2, n=40), individuals with RA specific symptoms (FDR 3, n=38) and chronic RA patients (cRA, n=45), recruited via the SCREEN-RA and SCQM cohort. (B) Serum calprotectin levels in healthy blood donors (BD, n=20), and patients newly diagnosed with non-rheumatic disease (NRD, n=35), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=50), axial spondyloarthritis (axSpA, n=30) and reactive arthritis (ReA, n=10), recruited via the Rheuma-VOR cohort. (C) Serum C-reactive protein (CRP) levels in NRD (n=34), RA (n=33), PsA (n=50) and axSpA (n=28) patients from the Rheuma-VOR cohort. (D) Spearman correlation between serum CRP and serum calprotectin measured in patients from the Rheuma-VOR cohort. (E) Serum calprotectin levels in FDR individuals and cRA patients from the SCREEN-RA/SCQM cohort and RA patients from the Rheuma-VOR cohort divided by RF and ACPA positivity. Statistical differences between positive and negative groups within patient groups were calculated using Mann-Whitney test. (F) Serum CRP levels in RA patients from the Rheuma-VOR cohort divided by RF and ACPA pre- and absence. Statistical differences between groups were calculated using Mann-Whitney test. (G) Serum zonulin levels in healthy blood donors (BD, n=20), patients newly diagnosed with non-rheumatic disease (NRD, n=22), rheumatoid arthritis (RA, n=33), psoriatic arthritis (PsA, n=48), axial spondyloarthritis (axSpA, n=30), reactive arthritis (ReA, n=10), as well as IBD patients with active ulcerative colitis (UC A, n=14), active Crohn’s disease (CD A, n=13), and Crohn’s disease under remission (CD R, n=12). Dots in the Rheuma-VOR groups depict single measurements, while dots in the IBD groups represent median values calculated from 2 replicates. (H) Serum zonulin in Rheuma-VOR RA patients clustered by RF and ACPA positivity. Statistical differences between groups were calculated using Mann-Whitney test. Data is shown as mean ± SD, *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; not significant if not further indicated.

    Article Snippet: Serum zonulin was measured using the IDK Zonulin ELISA Kit from Immundiagnostik AG, Cat: K5601, following the manufacturer’s instructions.

    Techniques: MANN-WHITNEY