tcc, human, mab ae11, fitc  (Hycult Biotech)


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    Hycult Biotech tcc, human, mab ae11, fitc
    Tcc, Human, Mab Ae11, Fitc, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 93 stars, based on 1 article reviews
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    tcc, human, mab ae11, fitc  (Hycult Biotech)


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    Hycult Biotech tcc, human, mab ae11, fitc
    Tcc, Human, Mab Ae11, Fitc, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    human terminal complement complex specific mab ae11  (Hycult Biotech)


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    Hycult Biotech human terminal complement complex specific mab ae11
    Surface plasmon resonance analysis of polymerization. Preparations of C9 were polished by size exchange chromatography to remove aggregates and flowed slowly (5 μl/min) at 37°C across a Biacore chip that had been immobilized with <t>aE11</t> mAb specific for polymerized C9. Polymers of C9 formed by WT and P167S C9 were captured on the antibody. Solid line represents poly-C9 captured from the preparation of mutant P167S C9 and dashed line represents capture of poly-C9 in the WT preparation. The experiment was performed multiple times with different preparations of C9; a representative analysis is illustrated.
    Human Terminal Complement Complex Specific Mab Ae11, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human terminal complement complex specific mab ae11/product/Hycult Biotech
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    human terminal complement complex specific mab ae11 - by Bioz Stars, 2024-05
    93/100 stars

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    1) Product Images from "The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade"

    Article Title: The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade

    Journal: Human Molecular Genetics

    doi: 10.1093/hmg/ddab086

    Surface plasmon resonance analysis of polymerization. Preparations of C9 were polished by size exchange chromatography to remove aggregates and flowed slowly (5 μl/min) at 37°C across a Biacore chip that had been immobilized with aE11 mAb specific for polymerized C9. Polymers of C9 formed by WT and P167S C9 were captured on the antibody. Solid line represents poly-C9 captured from the preparation of mutant P167S C9 and dashed line represents capture of poly-C9 in the WT preparation. The experiment was performed multiple times with different preparations of C9; a representative analysis is illustrated.
    Figure Legend Snippet: Surface plasmon resonance analysis of polymerization. Preparations of C9 were polished by size exchange chromatography to remove aggregates and flowed slowly (5 μl/min) at 37°C across a Biacore chip that had been immobilized with aE11 mAb specific for polymerized C9. Polymers of C9 formed by WT and P167S C9 were captured on the antibody. Solid line represents poly-C9 captured from the preparation of mutant P167S C9 and dashed line represents capture of poly-C9 in the WT preparation. The experiment was performed multiple times with different preparations of C9; a representative analysis is illustrated.

    Techniques Used: SPR Assay, Chromatography, Mutagenesis

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    Hycult Biotech tcc, human, mab ae11, fitc
    Tcc, Human, Mab Ae11, Fitc, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tcc, human, mab ae11, fitc/product/Hycult Biotech
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
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    Hycult Biotech human terminal complement complex specific mab ae11
    Surface plasmon resonance analysis of polymerization. Preparations of C9 were polished by size exchange chromatography to remove aggregates and flowed slowly (5 μl/min) at 37°C across a Biacore chip that had been immobilized with <t>aE11</t> mAb specific for polymerized C9. Polymers of C9 formed by WT and P167S C9 were captured on the antibody. Solid line represents poly-C9 captured from the preparation of mutant P167S C9 and dashed line represents capture of poly-C9 in the WT preparation. The experiment was performed multiple times with different preparations of C9; a representative analysis is illustrated.
    Human Terminal Complement Complex Specific Mab Ae11, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human terminal complement complex specific mab ae11/product/Hycult Biotech
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    human terminal complement complex specific mab ae11 - by Bioz Stars, 2024-05
    93/100 stars
      Buy from Supplier

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    Surface plasmon resonance analysis of polymerization. Preparations of C9 were polished by size exchange chromatography to remove aggregates and flowed slowly (5 μl/min) at 37°C across a Biacore chip that had been immobilized with aE11 mAb specific for polymerized C9. Polymers of C9 formed by WT and P167S C9 were captured on the antibody. Solid line represents poly-C9 captured from the preparation of mutant P167S C9 and dashed line represents capture of poly-C9 in the WT preparation. The experiment was performed multiple times with different preparations of C9; a representative analysis is illustrated.

    Journal: Human Molecular Genetics

    Article Title: The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade

    doi: 10.1093/hmg/ddab086

    Figure Lengend Snippet: Surface plasmon resonance analysis of polymerization. Preparations of C9 were polished by size exchange chromatography to remove aggregates and flowed slowly (5 μl/min) at 37°C across a Biacore chip that had been immobilized with aE11 mAb specific for polymerized C9. Polymers of C9 formed by WT and P167S C9 were captured on the antibody. Solid line represents poly-C9 captured from the preparation of mutant P167S C9 and dashed line represents capture of poly-C9 in the WT preparation. The experiment was performed multiple times with different preparations of C9; a representative analysis is illustrated.

    Article Snippet: Flat-bottomed 96-well plates (Maxisorp, ThermoFisher) were coated with 0.5 μg/ml human terminal complement complex-specific mAb aE11 (Hycult, HM2167, Uden, The Netherlands) in 200 m m bicarbonate/carbonate buffer pH 9.6 and incubated overnight at 4°C.

    Techniques: SPR Assay, Chromatography, Mutagenesis