Journal: Discover Oncology
Article Title: DPH2 is a biomarker associated with cell death, immunity and prognosis based on pan-cancer analysis
doi: 10.1007/s12672-025-01924-6
Figure Lengend Snippet: Knockdown of DPH2 inhibits cell proliferation, migration and invasion in vitro. A Analysis of the CELL database showing that DPH2 was most highly expressed in 22RV1 among various prostate cancer cell lines. B qRT-PCR validation of DPH2 knockdown efficiency in 22RV1 cells. C CCK-8 assay showing that DPH2 knockdown inhibits 22RV1 cell proliferation. D Transwell assay revealing significant effects of DPH2 knockdown on 22RV1 cell invasion. E DPH2 knockdown significantly inhibited 22RV1 cell migration. **P < 0.01, ***P < 0.001, ****P < 0.0001
Article Snippet: The human prostate cancer cell line, 22RV1, was obtained from American Type Culture Collection (ATCC; Manassas, VA).
Techniques: Knockdown, Migration, In Vitro, Quantitative RT-PCR, CCK-8 Assay, Transwell Assay