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human peripheral blood mononuclear cells pbmcs  (ATCC)
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Comparative induction of T cell exhaustion markers in colorectal cancer cell lines upon PBMC co-culture. Bar graph showing relative expression (fold change vs. monoculture baseline) of PDCD1, LAG3, HAVCR2, and CD27 in MSI-H cell lines (HCT116 and RKO) and MSS cell lines (HCT15 and SW480) following 48-h co-culture with activated <t>PBMCs.</t> Gray dashed line represents monoculture baseline (fold change = 1). MSI-H cell lines consistently demonstrated 2-3 times higher induction of all four exhaustion markers compared to MSS cell lines, with PDCD1 and LAG3 showing the greatest differential responses. Data represent mean values from three independent biological replicates analyzed by qRT-PCR with GAPDH normalization using the 2 -ΔΔCt method.
Human Peripheral Blood Mononuclear Cells Pbmcs, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hpbmcs/pmc13258542-88-0-11?v=ATCC
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human peripheral blood mononuclear cells pbmcs - by Bioz Stars, 2026-08
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hla a matched hpbmc  (Sanquin)
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Sanquin hla a matched hpbmc
Comparative induction of T cell exhaustion markers in colorectal cancer cell lines upon PBMC co-culture. Bar graph showing relative expression (fold change vs. monoculture baseline) of PDCD1, LAG3, HAVCR2, and CD27 in MSI-H cell lines (HCT116 and RKO) and MSS cell lines (HCT15 and SW480) following 48-h co-culture with activated <t>PBMCs.</t> Gray dashed line represents monoculture baseline (fold change = 1). MSI-H cell lines consistently demonstrated 2-3 times higher induction of all four exhaustion markers compared to MSS cell lines, with PDCD1 and LAG3 showing the greatest differential responses. Data represent mean values from three independent biological replicates analyzed by qRT-PCR with GAPDH normalization using the 2 -ΔΔCt method.
Hla A Matched Hpbmc, supplied by Sanquin, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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hla a matched hpbmc - by Bioz Stars, 2026-08
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1k human peripheral blood mononuclear cells pbmcs  (10X Genomics)
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10X Genomics 1k human peripheral blood mononuclear cells pbmcs
Comparative induction of T cell exhaustion markers in colorectal cancer cell lines upon PBMC co-culture. Bar graph showing relative expression (fold change vs. monoculture baseline) of PDCD1, LAG3, HAVCR2, and CD27 in MSI-H cell lines (HCT116 and RKO) and MSS cell lines (HCT15 and SW480) following 48-h co-culture with activated <t>PBMCs.</t> Gray dashed line represents monoculture baseline (fold change = 1). MSI-H cell lines consistently demonstrated 2-3 times higher induction of all four exhaustion markers compared to MSS cell lines, with PDCD1 and LAG3 showing the greatest differential responses. Data represent mean values from three independent biological replicates analyzed by qRT-PCR with GAPDH normalization using the 2 -ΔΔCt method.
1k Human Peripheral Blood Mononuclear Cells Pbmcs, supplied by 10X Genomics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hpbmcs/pmc13171171-61-12-20?v=10X+Genomics
Average 86 stars, based on 1 article reviews
1k human peripheral blood mononuclear cells pbmcs - by Bioz Stars, 2026-08
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human peripheral blood mononuclear cells  (Charles River Laboratories)
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Charles River Laboratories human peripheral blood mononuclear cells
Comparative induction of T cell exhaustion markers in colorectal cancer cell lines upon PBMC co-culture. Bar graph showing relative expression (fold change vs. monoculture baseline) of PDCD1, LAG3, HAVCR2, and CD27 in MSI-H cell lines (HCT116 and RKO) and MSS cell lines (HCT15 and SW480) following 48-h co-culture with activated <t>PBMCs.</t> Gray dashed line represents monoculture baseline (fold change = 1). MSI-H cell lines consistently demonstrated 2-3 times higher induction of all four exhaustion markers compared to MSS cell lines, with PDCD1 and LAG3 showing the greatest differential responses. Data represent mean values from three independent biological replicates analyzed by qRT-PCR with GAPDH normalization using the 2 -ΔΔCt method.
Human Peripheral Blood Mononuclear Cells, supplied by Charles River Laboratories, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hpbmcs/bio_rxiv__64898__2026__04__25__720815-91-1-6?v=Charles+River+Laboratories
Average 86 stars, based on 1 article reviews
human peripheral blood mononuclear cells - by Bioz Stars, 2026-08
86/100 stars
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human peripheral blood mononuclear cells  (ATCC)
99
ATCC human peripheral blood mononuclear cells
Comparative induction of T cell exhaustion markers in colorectal cancer cell lines upon PBMC co-culture. Bar graph showing relative expression (fold change vs. monoculture baseline) of PDCD1, LAG3, HAVCR2, and CD27 in MSI-H cell lines (HCT116 and RKO) and MSS cell lines (HCT15 and SW480) following 48-h co-culture with activated <t>PBMCs.</t> Gray dashed line represents monoculture baseline (fold change = 1). MSI-H cell lines consistently demonstrated 2-3 times higher induction of all four exhaustion markers compared to MSS cell lines, with PDCD1 and LAG3 showing the greatest differential responses. Data represent mean values from three independent biological replicates analyzed by qRT-PCR with GAPDH normalization using the 2 -ΔΔCt method.
Human Peripheral Blood Mononuclear Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hpbmcs/pm41998669-95-28-35?v=ATCC
Average 99 stars, based on 1 article reviews
human peripheral blood mononuclear cells - by Bioz Stars, 2026-08
99/100 stars
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human peripheral blood mononuclear cells  (Cambridge Bioscience)
86
Cambridge Bioscience human peripheral blood mononuclear cells
Comparative induction of T cell exhaustion markers in colorectal cancer cell lines upon PBMC co-culture. Bar graph showing relative expression (fold change vs. monoculture baseline) of PDCD1, LAG3, HAVCR2, and CD27 in MSI-H cell lines (HCT116 and RKO) and MSS cell lines (HCT15 and SW480) following 48-h co-culture with activated <t>PBMCs.</t> Gray dashed line represents monoculture baseline (fold change = 1). MSI-H cell lines consistently demonstrated 2-3 times higher induction of all four exhaustion markers compared to MSS cell lines, with PDCD1 and LAG3 showing the greatest differential responses. Data represent mean values from three independent biological replicates analyzed by qRT-PCR with GAPDH normalization using the 2 -ΔΔCt method.
Human Peripheral Blood Mononuclear Cells, supplied by Cambridge Bioscience, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hpbmcs/pm41912649-135-2-26?v=Cambridge+Bioscience
Average 86 stars, based on 1 article reviews
human peripheral blood mononuclear cells - by Bioz Stars, 2026-08
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Comparative induction of T cell exhaustion markers in colorectal cancer cell lines upon PBMC co-culture. Bar graph showing relative expression (fold change vs. monoculture baseline) of PDCD1, LAG3, HAVCR2, and CD27 in MSI-H cell lines (HCT116 and RKO) and MSS cell lines (HCT15 and SW480) following 48-h co-culture with activated PBMCs. Gray dashed line represents monoculture baseline (fold change = 1). MSI-H cell lines consistently demonstrated 2-3 times higher induction of all four exhaustion markers compared to MSS cell lines, with PDCD1 and LAG3 showing the greatest differential responses. Data represent mean values from three independent biological replicates analyzed by qRT-PCR with GAPDH normalization using the 2 -ΔΔCt method.

Journal: Frontiers in Genetics

Article Title: Single-cell transcriptomic profiling reveals CD27 + cytotoxic T Cell heterogeneity and exhaustion dynamics in colorectal cancer tumor microenvironment

doi: 10.3389/fgene.2026.1808171

Figure Lengend Snippet: Comparative induction of T cell exhaustion markers in colorectal cancer cell lines upon PBMC co-culture. Bar graph showing relative expression (fold change vs. monoculture baseline) of PDCD1, LAG3, HAVCR2, and CD27 in MSI-H cell lines (HCT116 and RKO) and MSS cell lines (HCT15 and SW480) following 48-h co-culture with activated PBMCs. Gray dashed line represents monoculture baseline (fold change = 1). MSI-H cell lines consistently demonstrated 2-3 times higher induction of all four exhaustion markers compared to MSS cell lines, with PDCD1 and LAG3 showing the greatest differential responses. Data represent mean values from three independent biological replicates analyzed by qRT-PCR with GAPDH normalization using the 2 -ΔΔCt method.

Article Snippet: Human peripheral blood mononuclear cells (PBMCs) were obtained commercially from the American Type Culture Collection (ATCC; catalog no. PCS-800-011) and used in accordance with the supplier’s guidelines.

Techniques: Co-Culture Assay, Expressing, Quantitative RT-PCR