hff 1 cells (ATCC)


Structured Review
Hff 1 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hff 1 cells/product/ATCC
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
human foreskin fibroblast 1 hff 1 cell line (ATCC)


Structured Review
Human Foreskin Fibroblast 1 Hff 1 Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human foreskin fibroblast 1 hff 1 cell line/product/ATCC
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
hff 1 cells (ATCC)


Structured Review
Hff 1 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hff 1 cells/product/ATCC
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
human foreskin fibroblast cell line hff 1 (ATCC)


Structured Review
Human Foreskin Fibroblast Cell Line Hff 1, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human foreskin fibroblast cell line hff 1/product/ATCC
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
hff 1 cells (ATCC)


Structured Review

Hff 1 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hff 1 cells/product/ATCC
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "A validated protocol to UV-inactivate SARS-CoV-2 and herpesvirus-infected cells"
Article Title: A validated protocol to UV-inactivate SARS-CoV-2 and herpesvirus-infected cells
Journal: PLOS ONE
doi: 10.1371/journal.pone.0274065

Figure Legend Snippet: HFF-1 cells infected with HCMV were UV-inactivated. (A) The virus titres of samples taken during inactivation validation were determined with a limit of detection (LoD) of 5 PFU/mL. The before inactivation and UV inactivated samples were performed with biological replicates, n = 3, and the standard deviation is shown. The untreated control sample was performed with n = 1. (B) Immunofluorescence imaging of cells treated with the UV-inactivated infected cells was performed with biological replicates, n = 3. Cells were stained for the HCMV proteins IE1/2 and with DAPI. The scale bar represents 100 μm.
Techniques Used: Infection, Standard Deviation, Immunofluorescence, Imaging, Staining
hff 1 cells (ATCC)


Structured Review

Hff 1 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hff 1 cells/product/ATCC
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses"
Article Title: Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses
Journal: Cell Reports Medicine
doi: 10.1016/j.xcrm.2023.101024

Figure Legend Snippet: Broad-spectrum antiviral screen (A) Schematic of antiviral screen performed using molecules modulating PAMPs. (B) Immunofluorescence images of human fibroblasts (HFF-1) infected with indicated viruses are shown. CHIKV (MOI: 0.1) and ZIKV (MOI: 0.1) or WNV (MOI: 1) were detected by anti-E1 protein and anti-flavivirus E protein antibodies, respectively. Scale bar: 25 μm. (C) Graph shows the percentage of infectivity of various compounds targeting CHIKV and flaviviruses. Horizontal dotted line indicates 50% infectivity. (D) Immunofluorescence images show phospho-IRF3 (S386) and phospho-STING (S366) in fibroblast after 2-h post-stimulation with indicated compounds. Note: scleroglucan-stimulated cells do not have detectable level of phospho-STING, and only a few cells have a cytoplasmic form of phospho-IRF3. Scale bar: 10 μm. See also
Techniques Used: Immunofluorescence, Infection
![Comparative transcriptome analysis of drug-treated and arbovirus-infected human fibroblasts (A) Violin plot shows comparative analysis of differentially expressed genes of vehicle- or cAIMP-treated virus-infected HFF-1 cells at 24 hpi. (B) Venn diagrams display the number of common and distinctive genes upregulated in virus-infected cells (left) as well as in cAIMP-treated virus-infected cells (right) at 24 hpi (false discovery rate [FDR] < 0.01 and log 2 fold change [log2FC] > 1). (C) Graphs show qRT-PCR analysis of innate immune STING pathway genes in arbovirus-infected fibroblasts at 48 hpi with or without drug treatments of infected cells. Student’s t test. ∗p > 0.01, ∗∗p > 0.001, ∗∗∗p > 0.0001. (D and E) Dot plot analysis of overrepresented pathways in viral-infected (D) and cAIMP-treated virus-infected cells (E). The size of the dot represents the fold enrichment (FoldEnrich), while its color represents the FDR (p adjusted) value for each enriched Reactome pathway. The x axis represents the percentage of upregulated genes in the selected pathway that is presented in the y axis. See also <xref ref-type=](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_3809/pmc10213809/pmc10213809__gr3.jpg)
Figure Legend Snippet: Comparative transcriptome analysis of drug-treated and arbovirus-infected human fibroblasts (A) Violin plot shows comparative analysis of differentially expressed genes of vehicle- or cAIMP-treated virus-infected HFF-1 cells at 24 hpi. (B) Venn diagrams display the number of common and distinctive genes upregulated in virus-infected cells (left) as well as in cAIMP-treated virus-infected cells (right) at 24 hpi (false discovery rate [FDR] < 0.01 and log 2 fold change [log2FC] > 1). (C) Graphs show qRT-PCR analysis of innate immune STING pathway genes in arbovirus-infected fibroblasts at 48 hpi with or without drug treatments of infected cells. Student’s t test. ∗p > 0.01, ∗∗p > 0.001, ∗∗∗p > 0.0001. (D and E) Dot plot analysis of overrepresented pathways in viral-infected (D) and cAIMP-treated virus-infected cells (E). The size of the dot represents the fold enrichment (FoldEnrich), while its color represents the FDR (p adjusted) value for each enriched Reactome pathway. The x axis represents the percentage of upregulated genes in the selected pathway that is presented in the y axis. See also
Techniques Used: Infection, Quantitative RT-PCR

Figure Legend Snippet:
Techniques Used: Produced, Recombinant, Electron Microscopy, Cell Culture, Cell Viability Assay, Infection, Expressing, Derivative Assay, In Vivo, Software
human fibroblast hff 1 cells (ATCC)


Structured Review

Human Fibroblast Hff 1 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human fibroblast hff 1 cells/product/ATCC
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Development of Imeglimin Electrospun Nanofibers as a Potential Buccal Antidiabetic Therapeutic Approach"
Article Title: Development of Imeglimin Electrospun Nanofibers as a Potential Buccal Antidiabetic Therapeutic Approach
Journal: Pharmaceutics
doi: 10.3390/pharmaceutics15041208

Figure Legend Snippet: Cell viability of different doses of imeglimin upon 24 h HFF-1 cells exposure. The data demonstrated that imeglimin is safe at ≤250 µg/mL. Results are presented as mean ± SD (n = 3).
Techniques Used:
human fibroblast cell lineage hff 1 (ATCC)


Structured Review
Human Fibroblast Cell Lineage Hff 1, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human fibroblast cell lineage hff 1/product/ATCC
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
hff 1 cells (ATCC)


Structured Review
Hff 1 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hff 1 cells/product/ATCC
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
hff 1 cells (ATCC)


Structured Review

Hff 1 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hff 1 cells/product/ATCC
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Microbially Synthesized Polymer-Metal Nanoparticles Composites as Promising Wound Dressings to Overcome Methicillin-Resistance Staphylococcus aureus Infections"
Article Title: Microbially Synthesized Polymer-Metal Nanoparticles Composites as Promising Wound Dressings to Overcome Methicillin-Resistance Staphylococcus aureus Infections
Journal: Polymers
doi: 10.3390/polym15040920

Figure Legend Snippet: Biocompatibility of PHO active films. ( A ) viability test on HFF-1 cells after 24 h of exposure; ( B ) genotoxicity assay on HFF-1 cells after 3 h of exposure; ( C ) hemolysis caused by neat PHO films and bioactive PHO films; and ( D ) platelet aggregation of human plasma on active PHO and neat PHO films after 3 min of exposure. Mean values with different letters represent significant differences ( p < 0.05). C− (negative control), C+ (positive control), SS (saline solution), and DW (distilled water).
Techniques Used: Negative Control, Positive Control