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human embryonic kidney 293 t hek293t cells  (ATCC)
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ATCC human embryonic kidney 293 t hek293t cells
Comparative analysis of PGRMC1 interactome. (a) Venn diagram of identified PGRMC1 prey from MEL, <t>HEK293T</t> (HEK), and HepG2 cell lines filtered using the CRAPome repository. (b) Heatmap of PGRMC1 interactome common in all three cells lines using the normalized FC values, represented by color scale (2.0 to 0.0) with all values greater than 0.0. Prey proteins previously identified as candidate proteins of MAMs indicated with asterisk (*). (c) Bar graph of biological process enrichment profile of 70 proteins found in the core PGRMC1 interactome in MEL, HEK293T (HEK), and HepG2 cells. X-axis shows −log 10 of adjusted p -value (p adj ) and Y-axis the biological process. (d) Bar graph of pathway enrichment profile of proteins found in at least two cell lines. Top four biological processes shown for each cell line combination. X-axis shows −log 10 of adjusted p-value and Y-axis the biological process. (e) Bar graph of gene ontology (GO), cellular compartment (CC), biological process (BP), and molecular function (MF) of common PGRMC1 and FECH interactome proteins. X-axis shows −log 10 of adjusted p-value and Y-axis is GO aspect.
Human Embryonic Kidney 293 T Hek293t Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human embryonic kidney 293 t hek293t cells - by Bioz Stars, 2026-04
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human embryonic kidney 293 cells expressing sv40 large t antigen hek293t cells  (ATCC)
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ATCC human embryonic kidney 293 cells expressing sv40 large t antigen hek293t cells
Comparative analysis of PGRMC1 interactome. (a) Venn diagram of identified PGRMC1 prey from MEL, <t>HEK293T</t> (HEK), and HepG2 cell lines filtered using the CRAPome repository. (b) Heatmap of PGRMC1 interactome common in all three cells lines using the normalized FC values, represented by color scale (2.0 to 0.0) with all values greater than 0.0. Prey proteins previously identified as candidate proteins of MAMs indicated with asterisk (*). (c) Bar graph of biological process enrichment profile of 70 proteins found in the core PGRMC1 interactome in MEL, HEK293T (HEK), and HepG2 cells. X-axis shows −log 10 of adjusted p -value (p adj ) and Y-axis the biological process. (d) Bar graph of pathway enrichment profile of proteins found in at least two cell lines. Top four biological processes shown for each cell line combination. X-axis shows −log 10 of adjusted p-value and Y-axis the biological process. (e) Bar graph of gene ontology (GO), cellular compartment (CC), biological process (BP), and molecular function (MF) of common PGRMC1 and FECH interactome proteins. X-axis shows −log 10 of adjusted p-value and Y-axis is GO aspect.
Human Embryonic Kidney 293 Cells Expressing Sv40 Large T Antigen Hek293t Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human embryonic kidney 293 cells expressing sv40 large t antigen hek293t cells/product/ATCC
Average 99 stars, based on 1 article reviews
human embryonic kidney 293 cells expressing sv40 large t antigen hek293t cells - by Bioz Stars, 2026-04
99/100 stars
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Comparative analysis of PGRMC1 interactome. (a) Venn diagram of identified PGRMC1 prey from MEL, HEK293T (HEK), and HepG2 cell lines filtered using the CRAPome repository. (b) Heatmap of PGRMC1 interactome common in all three cells lines using the normalized FC values, represented by color scale (2.0 to 0.0) with all values greater than 0.0. Prey proteins previously identified as candidate proteins of MAMs indicated with asterisk (*). (c) Bar graph of biological process enrichment profile of 70 proteins found in the core PGRMC1 interactome in MEL, HEK293T (HEK), and HepG2 cells. X-axis shows −log 10 of adjusted p -value (p adj ) and Y-axis the biological process. (d) Bar graph of pathway enrichment profile of proteins found in at least two cell lines. Top four biological processes shown for each cell line combination. X-axis shows −log 10 of adjusted p-value and Y-axis the biological process. (e) Bar graph of gene ontology (GO), cellular compartment (CC), biological process (BP), and molecular function (MF) of common PGRMC1 and FECH interactome proteins. X-axis shows −log 10 of adjusted p-value and Y-axis is GO aspect.

Journal: Journal of inorganic biochemistry

Article Title: Progesterone receptor membrane component 1 (PGRMC1) regulates Heme trafficking through mitochondria-ER junctions ☆

doi: 10.1016/j.jinorgbio.2025.113093

Figure Lengend Snippet: Comparative analysis of PGRMC1 interactome. (a) Venn diagram of identified PGRMC1 prey from MEL, HEK293T (HEK), and HepG2 cell lines filtered using the CRAPome repository. (b) Heatmap of PGRMC1 interactome common in all three cells lines using the normalized FC values, represented by color scale (2.0 to 0.0) with all values greater than 0.0. Prey proteins previously identified as candidate proteins of MAMs indicated with asterisk (*). (c) Bar graph of biological process enrichment profile of 70 proteins found in the core PGRMC1 interactome in MEL, HEK293T (HEK), and HepG2 cells. X-axis shows −log 10 of adjusted p -value (p adj ) and Y-axis the biological process. (d) Bar graph of pathway enrichment profile of proteins found in at least two cell lines. Top four biological processes shown for each cell line combination. X-axis shows −log 10 of adjusted p-value and Y-axis the biological process. (e) Bar graph of gene ontology (GO), cellular compartment (CC), biological process (BP), and molecular function (MF) of common PGRMC1 and FECH interactome proteins. X-axis shows −log 10 of adjusted p-value and Y-axis is GO aspect.

Article Snippet: Three mammalian cell lines were used for PGRMC1 interaction studies: murine erythroleukemia (MEL) cells [ , ] (a kind gift of the late Barry Paw, Harvard University), human embryonic kidney 293 T (HEK293T) cells (ATCC, CRL-3216), and human hepatocellular carcinoma (HepG2) cells (ATCC, HB-8065).

Techniques: