Journal: Antioxidants

Article Title: Phenolic Profile and Antioxidant Potential of Selected European Astragalus Species: Comparative UHPLC–DAD–ESI/TOF–MS and In Vitro Study

doi: 10.3390/antiox15060750

Figure Lengend Snippet: Effect of Astragalus extracts on AAPH-induced lipid peroxidation in the linoleic acid model system. Lipid peroxidation was determined using the TBARS method and expressed as malondialdehyde (MDA) equivalents. AMR— Astragalus membranaceus root, AMH— Astragalus membranaceus herb, ACR— Astragalus cicer root, ACH— Astragalus cicer herb, AGR— Astragalus glycyphyllos root, AGH— Astragalus glycyphyllos herb, CG—Calycosin-7-O- β -D-glucoside, C—Calycosin. Different superscript lowercase letters indicate a statistically significant difference between the fractions themselves and between the fractions and control within the same column, with p < 0.05.

Article Snippet: Chromatographic standards, such as astragaloside I, astragaloside II, astragaloside III, astragaloside IV and selected isoflavonoids characteristic of the genus Astragalus , namely, calycosin-7-O- β -D-glucoside, formononetin-7-O- β -D-glucopyranoside, calycosin and formononetin, were purchased from MedChemExpress (Monmouth Junction, NJ, USA).

Techniques: Control

Journal: Antioxidants

Article Title: Phenolic Profile and Antioxidant Potential of Selected European Astragalus Species: Comparative UHPLC–DAD–ESI/TOF–MS and In Vitro Study

doi: 10.3390/antiox15060750

Figure Lengend Snippet: Effect of Astragalus extracts on AAPH-induced lipid peroxidation in plasma. Lipid peroxidation was assessed by the TBARS method and expressed as MDA content (nmol MDA/mg protein). Results are presented as mean ± SD (n = 3). AMR— Astragalus membranaceus root, AMH— Astragalus membranaceus herb, ACR— Astragalus cicer root, ACH— Astragalus cicer herb, AGR— Astragalus glycyphyllos root, AGH— Astragalus glycyphyllos herb, CG—Calycosin-7-O- β -D-glucoside, C—Calycosin. Different superscript lowercase letters indicate a statistically significant difference between the fractions themselves and between the fractions and control within the same column, with p < 0.05.

Article Snippet: Chromatographic standards, such as astragaloside I, astragaloside II, astragaloside III, astragaloside IV and selected isoflavonoids characteristic of the genus Astragalus , namely, calycosin-7-O- β -D-glucoside, formononetin-7-O- β -D-glucopyranoside, calycosin and formononetin, were purchased from MedChemExpress (Monmouth Junction, NJ, USA).

Techniques: Clinical Proteomics, Control

Journal: Antioxidants

Article Title: Phenolic Profile and Antioxidant Potential of Selected European Astragalus Species: Comparative UHPLC–DAD–ESI/TOF–MS and In Vitro Study

doi: 10.3390/antiox15060750

Figure Lengend Snippet: Bioactivity profiles of the investigated Astragalus extracts presented as radar plots based on standardized Z-scores. Higher Z-score values indicate stronger biological activity of the extracts across the analyzed parameters.

Article Snippet: Chromatographic standards, such as astragaloside I, astragaloside II, astragaloside III, astragaloside IV and selected isoflavonoids characteristic of the genus Astragalus , namely, calycosin-7-O- β -D-glucoside, formononetin-7-O- β -D-glucopyranoside, calycosin and formononetin, were purchased from MedChemExpress (Monmouth Junction, NJ, USA).

Techniques: Activity Assay

Journal: Antioxidants

Article Title: Phenolic Profile and Antioxidant Potential of Selected European Astragalus Species: Comparative UHPLC–DAD–ESI/TOF–MS and In Vitro Study

doi: 10.3390/antiox15060750

Figure Lengend Snippet: Principal component analysis (PCA) of the investigated Astragalus extracts based on their phenolic composition and biological activity parameters, including antioxidant and enzyme inhibitory activities.

Article Snippet: Chromatographic standards, such as astragaloside I, astragaloside II, astragaloside III, astragaloside IV and selected isoflavonoids characteristic of the genus Astragalus , namely, calycosin-7-O- β -D-glucoside, formononetin-7-O- β -D-glucopyranoside, calycosin and formononetin, were purchased from MedChemExpress (Monmouth Junction, NJ, USA).

Techniques: Activity Assay

Journal: Antioxidants

Article Title: Phenolic Profile and Antioxidant Potential of Selected European Astragalus Species: Comparative UHPLC–DAD–ESI/TOF–MS and In Vitro Study

doi: 10.3390/antiox15060750

Figure Lengend Snippet: Correlation analysis (R) between antioxidant activity, enzyme inhibitory activity, and chemical composition of the analyzed Astragalus extracts. The color scale represents Pearson correlation coefficients, where deeper shades of blue indicate stronger positive correlations, whereas increasingly intense red colors indicate stronger negative correlations.

Article Snippet: Chromatographic standards, such as astragaloside I, astragaloside II, astragaloside III, astragaloside IV and selected isoflavonoids characteristic of the genus Astragalus , namely, calycosin-7-O- β -D-glucoside, formononetin-7-O- β -D-glucopyranoside, calycosin and formononetin, were purchased from MedChemExpress (Monmouth Junction, NJ, USA).

Techniques: Antioxidant Activity Assay, Activity Assay