gene exp mc1r hs00267167 s1  (Thermo Fisher)


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    Thermo Fisher gene exp mc1r hs00267167 s1
    Blood urea nitrogen (BUN) does not differ in untreated adriamycin mice compared with <t>MC1R</t> agonist treated mice. BUN was measured in plasma samples taken from mice 8–10 days after injection of adriamycin. There was no difference between the groups (n = 9–10, n.s.). Results are presented as mean ± SEM.
    Gene Exp Mc1r Hs00267167 S1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/gene exp mc1r hs00267167 s1/product/Thermo Fisher
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    gene exp mc1r hs00267167 s1 - by Bioz Stars, 2022-07
    86/100 stars

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    1) Product Images from "Effects of Melanocortin 1 Receptor Agonists in Experimental Nephropathies"

    Article Title: Effects of Melanocortin 1 Receptor Agonists in Experimental Nephropathies

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0087816

    Blood urea nitrogen (BUN) does not differ in untreated adriamycin mice compared with MC1R agonist treated mice. BUN was measured in plasma samples taken from mice 8–10 days after injection of adriamycin. There was no difference between the groups (n = 9–10, n.s.). Results are presented as mean ± SEM.
    Figure Legend Snippet: Blood urea nitrogen (BUN) does not differ in untreated adriamycin mice compared with MC1R agonist treated mice. BUN was measured in plasma samples taken from mice 8–10 days after injection of adriamycin. There was no difference between the groups (n = 9–10, n.s.). Results are presented as mean ± SEM.

    Techniques Used: Mouse Assay, Injection

    Albuminuria was reduced in MC1R agonist treated PHN rats. After four weeks of MS05 treatment (n = 17), the urinary albumin- to-creatinine ratio (UACR) was significantly reduced compared to untreated PHN (n = 14; p
    Figure Legend Snippet: Albuminuria was reduced in MC1R agonist treated PHN rats. After four weeks of MS05 treatment (n = 17), the urinary albumin- to-creatinine ratio (UACR) was significantly reduced compared to untreated PHN (n = 14; p

    Techniques Used:

    MC1R protein expression. Western blotting was performed in order to detect MC1R protein expression in mouse and human tissue. Left panel: incubation with a rabbit polyclonal MC1R antibody (Alomone Labs). Right panel: incubation with MC1R antibody and control blocking peptide antigen (BP) in order to show antibody specificity. A) mouse whole glomerular lysate, B) cultured wild type mouse podocytes and C) a human malignant melanoma cell line A375. MC1R protein expression was detected at the expected size of 37 kDa (left panel).
    Figure Legend Snippet: MC1R protein expression. Western blotting was performed in order to detect MC1R protein expression in mouse and human tissue. Left panel: incubation with a rabbit polyclonal MC1R antibody (Alomone Labs). Right panel: incubation with MC1R antibody and control blocking peptide antigen (BP) in order to show antibody specificity. A) mouse whole glomerular lysate, B) cultured wild type mouse podocytes and C) a human malignant melanoma cell line A375. MC1R protein expression was detected at the expected size of 37 kDa (left panel).

    Techniques Used: Expressing, Western Blot, Incubation, Blocking Assay, Cell Culture

    MC1R agonists did not reduce albuminuria in adriamycin-treated mice. (A) Five different doses of adriamycin, in the range of 5–10 mg/kg, were intravenously injected and the level of albuminuria was measured after 7 days. The urinary albumin-to-creatinine ratio (UACR) increased with increasing levels of adriamycin. (B) Albuminuria at day 7. Treatment with the MC1R agonist BMS-470539 did not reduce the level of albuminuria for the 8 mg/kg adriamycin dose, on the contrary it slightly increased albuminuria for the 10 mg/kg dose (n = 17–19, p
    Figure Legend Snippet: MC1R agonists did not reduce albuminuria in adriamycin-treated mice. (A) Five different doses of adriamycin, in the range of 5–10 mg/kg, were intravenously injected and the level of albuminuria was measured after 7 days. The urinary albumin-to-creatinine ratio (UACR) increased with increasing levels of adriamycin. (B) Albuminuria at day 7. Treatment with the MC1R agonist BMS-470539 did not reduce the level of albuminuria for the 8 mg/kg adriamycin dose, on the contrary it slightly increased albuminuria for the 10 mg/kg dose (n = 17–19, p

    Techniques Used: Mouse Assay, Injection

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    Thermo Fisher gene exp mc1r hs00267167 s1
    Blood urea nitrogen (BUN) does not differ in untreated adriamycin mice compared with <t>MC1R</t> agonist treated mice. BUN was measured in plasma samples taken from mice 8–10 days after injection of adriamycin. There was no difference between the groups (n = 9–10, n.s.). Results are presented as mean ± SEM.
    Gene Exp Mc1r Hs00267167 S1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/gene exp mc1r hs00267167 s1/product/Thermo Fisher
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    gene exp mc1r hs00267167 s1 - by Bioz Stars, 2022-07
    86/100 stars
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    Blood urea nitrogen (BUN) does not differ in untreated adriamycin mice compared with MC1R agonist treated mice. BUN was measured in plasma samples taken from mice 8–10 days after injection of adriamycin. There was no difference between the groups (n = 9–10, n.s.). Results are presented as mean ± SEM.

    Journal: PLoS ONE

    Article Title: Effects of Melanocortin 1 Receptor Agonists in Experimental Nephropathies

    doi: 10.1371/journal.pone.0087816

    Figure Lengend Snippet: Blood urea nitrogen (BUN) does not differ in untreated adriamycin mice compared with MC1R agonist treated mice. BUN was measured in plasma samples taken from mice 8–10 days after injection of adriamycin. There was no difference between the groups (n = 9–10, n.s.). Results are presented as mean ± SEM.

    Article Snippet: The following primers and probes, all verified by ABI, were used to detect mRNA of the following genes: GAPDH: Mm99999915_g1 (mouse), Rn01775763_g1 (rat), Hs99999905_m1 (human); MC1R: Mm00434851_s1 (mouse), custom made GenBankID AB306978.1 (rat), Hs00267167_s1 (human).

    Techniques: Mouse Assay, Injection

    Albuminuria was reduced in MC1R agonist treated PHN rats. After four weeks of MS05 treatment (n = 17), the urinary albumin- to-creatinine ratio (UACR) was significantly reduced compared to untreated PHN (n = 14; p

    Journal: PLoS ONE

    Article Title: Effects of Melanocortin 1 Receptor Agonists in Experimental Nephropathies

    doi: 10.1371/journal.pone.0087816

    Figure Lengend Snippet: Albuminuria was reduced in MC1R agonist treated PHN rats. After four weeks of MS05 treatment (n = 17), the urinary albumin- to-creatinine ratio (UACR) was significantly reduced compared to untreated PHN (n = 14; p

    Article Snippet: The following primers and probes, all verified by ABI, were used to detect mRNA of the following genes: GAPDH: Mm99999915_g1 (mouse), Rn01775763_g1 (rat), Hs99999905_m1 (human); MC1R: Mm00434851_s1 (mouse), custom made GenBankID AB306978.1 (rat), Hs00267167_s1 (human).

    Techniques:

    MC1R protein expression. Western blotting was performed in order to detect MC1R protein expression in mouse and human tissue. Left panel: incubation with a rabbit polyclonal MC1R antibody (Alomone Labs). Right panel: incubation with MC1R antibody and control blocking peptide antigen (BP) in order to show antibody specificity. A) mouse whole glomerular lysate, B) cultured wild type mouse podocytes and C) a human malignant melanoma cell line A375. MC1R protein expression was detected at the expected size of 37 kDa (left panel).

    Journal: PLoS ONE

    Article Title: Effects of Melanocortin 1 Receptor Agonists in Experimental Nephropathies

    doi: 10.1371/journal.pone.0087816

    Figure Lengend Snippet: MC1R protein expression. Western blotting was performed in order to detect MC1R protein expression in mouse and human tissue. Left panel: incubation with a rabbit polyclonal MC1R antibody (Alomone Labs). Right panel: incubation with MC1R antibody and control blocking peptide antigen (BP) in order to show antibody specificity. A) mouse whole glomerular lysate, B) cultured wild type mouse podocytes and C) a human malignant melanoma cell line A375. MC1R protein expression was detected at the expected size of 37 kDa (left panel).

    Article Snippet: The following primers and probes, all verified by ABI, were used to detect mRNA of the following genes: GAPDH: Mm99999915_g1 (mouse), Rn01775763_g1 (rat), Hs99999905_m1 (human); MC1R: Mm00434851_s1 (mouse), custom made GenBankID AB306978.1 (rat), Hs00267167_s1 (human).

    Techniques: Expressing, Western Blot, Incubation, Blocking Assay, Cell Culture

    MC1R agonists did not reduce albuminuria in adriamycin-treated mice. (A) Five different doses of adriamycin, in the range of 5–10 mg/kg, were intravenously injected and the level of albuminuria was measured after 7 days. The urinary albumin-to-creatinine ratio (UACR) increased with increasing levels of adriamycin. (B) Albuminuria at day 7. Treatment with the MC1R agonist BMS-470539 did not reduce the level of albuminuria for the 8 mg/kg adriamycin dose, on the contrary it slightly increased albuminuria for the 10 mg/kg dose (n = 17–19, p

    Journal: PLoS ONE

    Article Title: Effects of Melanocortin 1 Receptor Agonists in Experimental Nephropathies

    doi: 10.1371/journal.pone.0087816

    Figure Lengend Snippet: MC1R agonists did not reduce albuminuria in adriamycin-treated mice. (A) Five different doses of adriamycin, in the range of 5–10 mg/kg, were intravenously injected and the level of albuminuria was measured after 7 days. The urinary albumin-to-creatinine ratio (UACR) increased with increasing levels of adriamycin. (B) Albuminuria at day 7. Treatment with the MC1R agonist BMS-470539 did not reduce the level of albuminuria for the 8 mg/kg adriamycin dose, on the contrary it slightly increased albuminuria for the 10 mg/kg dose (n = 17–19, p

    Article Snippet: The following primers and probes, all verified by ABI, were used to detect mRNA of the following genes: GAPDH: Mm99999915_g1 (mouse), Rn01775763_g1 (rat), Hs99999905_m1 (human); MC1R: Mm00434851_s1 (mouse), custom made GenBankID AB306978.1 (rat), Hs00267167_s1 (human).

    Techniques: Mouse Assay, Injection