Journal: Biology
Article Title: Using a Combination of Novel Research Tools to Understand Social Interaction in the Drosophila melanogaster Model for Fragile X Syndrome
doi: 10.3390/biology13060432
Figure Lengend Snippet: Differences between dFMR1 B55 and w 1118 in activity and Social Interaction Network (SIN) measures. Column bar graph (mean and standard deviation) for 15 dFMR1 B55 ( n = 450 flies) and 15 w 1118 groups ( n = 450 flies), for the following measures: ( a ) total distance traveled expressed in mm; ( b ) velocity expressed in mm/s; ( c ) total edges; ( d ) average degree; ( e ) average in/out strength weighted for count; ( f ) average in/out strength weighted for duration; ( g ) network density; ( h ) global efficiency; ( i ) heterogeneity; ( j ) assortativity; ( k ) transitivity; ( l ) average clustering coefficient; ( m ) average betweenness centrality; ( n ) average closeness centrality; and ( o ) modularity. Data are extracted from 15 min videos using FlyTracker and analyzed using the Python data processing pipeline. p -values less than 0.05 are taken as significant. Column bars represent the mean values of 450 flies per group (15 experiments with 30 flies per group) with the whiskers representing the standard deviation. This information can be useful for understanding the high variability in almost all the graphs. Abbreviations: *** p < 0.0001; dFMR1 B55 - Drosophila melanogaster model of fragile X syndrome; w 1118 —wild type, Drosophila melanogaster.
Article Snippet: Fly tracking was done using the open source software Caltech FlyTracker 1.1.2, developed using MATLAB v. R2023a.
Techniques: Activity Assay, Standard Deviation
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