Structured Review

ICN Biomedicals fluconazole
CYP51 inhibitors and catalytic reaction. A , structural formulas of the marketed drugs, 1,2,4-triazoles voriconazole ( Vor ), <t>fluconazole</t> ( Fluc ), and posaconazole ( Poz ), and an experimental CYP51 inhibitor, the 1,3-imidazole VNI. The heme-coordinating nitrogen
Fluconazole, supplied by ICN Biomedicals, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/fluconazole/product/ICN Biomedicals
Average 91 stars, based on 1 article reviews
Price from $9.99 to $1999.99
fluconazole - by Bioz Stars, 2020-09
91/100 stars

Images

1) Product Images from "Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs *"

Article Title: Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs *

Journal: The Journal of Biological Chemistry

doi: 10.1074/jbc.M115.677310

CYP51 inhibitors and catalytic reaction. A , structural formulas of the marketed drugs, 1,2,4-triazoles voriconazole ( Vor ), fluconazole ( Fluc ), and posaconazole ( Poz ), and an experimental CYP51 inhibitor, the 1,3-imidazole VNI. The heme-coordinating nitrogen
Figure Legend Snippet: CYP51 inhibitors and catalytic reaction. A , structural formulas of the marketed drugs, 1,2,4-triazoles voriconazole ( Vor ), fluconazole ( Fluc ), and posaconazole ( Poz ), and an experimental CYP51 inhibitor, the 1,3-imidazole VNI. The heme-coordinating nitrogen

Techniques Used:

2) Product Images from "Deletion of the Uracil Permease Gene Confers Cross-Resistance to 5-Fluorouracil and Azoles in Candida lusitaniae and Highlights Antagonistic Interaction between Fluorinated Nucleotides and Fluconazole"

Article Title: Deletion of the Uracil Permease Gene Confers Cross-Resistance to 5-Fluorouracil and Azoles in Candida lusitaniae and Highlights Antagonistic Interaction between Fluorinated Nucleotides and Fluconazole

Journal: Antimicrobial Agents and Chemotherapy

doi: 10.1128/AAC.00009-14

Resistance to fluconazole can be induced in other species of Candida using flucytosine, 5-fluorouracil, and 5-fluorouridine.
Figure Legend Snippet: Resistance to fluconazole can be induced in other species of Candida using flucytosine, 5-fluorouracil, and 5-fluorouridine.

Techniques Used:

Etest determination of the fluconazole MIC of the C. lusitaniae fur4 Δ and fur1 Δ mutant strains on RPMI medium supplemented with increasing concentrations of 5FU or left unsupplemented.
Figure Legend Snippet: Etest determination of the fluconazole MIC of the C. lusitaniae fur4 Δ and fur1 Δ mutant strains on RPMI medium supplemented with increasing concentrations of 5FU or left unsupplemented.

Techniques Used: Mutagenesis

Growth of the antifungal-susceptible wild-type strain 6936 in RPMI supplemented with inhibitory concentrations of fluconazole along with various low concentrations of 5-fluorouracil (A) or flucytosine (B). Growth is given as a percentage of the growth
Figure Legend Snippet: Growth of the antifungal-susceptible wild-type strain 6936 in RPMI supplemented with inhibitory concentrations of fluconazole along with various low concentrations of 5-fluorouracil (A) or flucytosine (B). Growth is given as a percentage of the growth

Techniques Used:

Growth of C. guilliermondii ATCC 6260, C. glabrata ATCC 90030, and C. tropicalis IP1275 in RPMI medium supplemented with inhibitory concentrations of fluconazole (4× the MIC for each strain) in the presence of different concentrations of the fluoropyrimidines
Figure Legend Snippet: Growth of C. guilliermondii ATCC 6260, C. glabrata ATCC 90030, and C. tropicalis IP1275 in RPMI medium supplemented with inhibitory concentrations of fluconazole (4× the MIC for each strain) in the presence of different concentrations of the fluoropyrimidines

Techniques Used:

Growth of wild-type and ura3 Δ strains of C. lusitaniae in RMPI supplemented with 8 μg/ml fluconazole and different concentrations of 5FOA. Growth is expressed as the percentage of growth observed in inhibitor-free RPMI. The lack of bars
Figure Legend Snippet: Growth of wild-type and ura3 Δ strains of C. lusitaniae in RMPI supplemented with 8 μg/ml fluconazole and different concentrations of 5FOA. Growth is expressed as the percentage of growth observed in inhibitor-free RPMI. The lack of bars

Techniques Used:

Resistance to fluconazole can be induced in other species of Candida using flucytosine, 5-fluorouracil, and 5-fluorouridine.
Figure Legend Snippet: Resistance to fluconazole can be induced in other species of Candida using flucytosine, 5-fluorouracil, and 5-fluorouridine.

Techniques Used:

Related Articles

other:

Article Title: Potato Dextrose Agar Antifungal Susceptibility Testing for Yeasts and Molds: Evaluation of Phosphate Effect on Antifungal Activity of CMT-3
Article Snippet: Itraconazole and ketoconazole were purchased from Research Diagnostics Inc. (Flanders, N.J.), fluconazole was obtained from ICN Biomedicals Inc. (Aurora, Ohio), and CMT-3 was provided by Collagenex Pharmaceutical, Inc. (Newtown, Pa.).

Article Title: Structural analyses of Candida albicans sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis
Article Snippet: Voriconazole, ketoconazole, itraconazole, and posaconazole were purchased from Santa Cruz Biotechnology, and fluconazole, clotrimazole, and miconazole were from ICN Biomedicals.

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    ICN Biomedicals fluconazole
    CYP51 inhibitors and catalytic reaction. A , structural formulas of the marketed drugs, 1,2,4-triazoles voriconazole ( Vor ), <t>fluconazole</t> ( Fluc ), and posaconazole ( Poz ), and an experimental CYP51 inhibitor, the 1,3-imidazole VNI. The heme-coordinating nitrogen
    Fluconazole, supplied by ICN Biomedicals, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/fluconazole/product/ICN Biomedicals
    Average 91 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    fluconazole - by Bioz Stars, 2020-09
    91/100 stars
      Buy from Supplier

    89
    ICN Biomedicals fluconazole flc
    CYP51 inhibitors and catalytic reaction. A , structural formulas of the marketed drugs, 1,2,4-triazoles voriconazole ( Vor ), <t>fluconazole</t> ( Fluc ), and posaconazole ( Poz ), and an experimental CYP51 inhibitor, the 1,3-imidazole VNI. The heme-coordinating nitrogen
    Fluconazole Flc, supplied by ICN Biomedicals, used in various techniques. Bioz Stars score: 89/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/fluconazole flc/product/ICN Biomedicals
    Average 89 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    fluconazole flc - by Bioz Stars, 2020-09
    89/100 stars
      Buy from Supplier

    Image Search Results


    CYP51 inhibitors and catalytic reaction. A , structural formulas of the marketed drugs, 1,2,4-triazoles voriconazole ( Vor ), fluconazole ( Fluc ), and posaconazole ( Poz ), and an experimental CYP51 inhibitor, the 1,3-imidazole VNI. The heme-coordinating nitrogen

    Journal: The Journal of Biological Chemistry

    Article Title: Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs *

    doi: 10.1074/jbc.M115.677310

    Figure Lengend Snippet: CYP51 inhibitors and catalytic reaction. A , structural formulas of the marketed drugs, 1,2,4-triazoles voriconazole ( Vor ), fluconazole ( Fluc ), and posaconazole ( Poz ), and an experimental CYP51 inhibitor, the 1,3-imidazole VNI. The heme-coordinating nitrogen

    Article Snippet: Voriconazole, ketoconazole, itraconazole, and posaconazole were purchased from Santa Cruz Biotechnology, Inc. (Dallas, TX); fluconazole, clotrimazole, and miconazole were from ICN Biomedicals.

    Techniques:

    Resistance to fluconazole can be induced in other species of Candida using flucytosine, 5-fluorouracil, and 5-fluorouridine.

    Journal: Antimicrobial Agents and Chemotherapy

    Article Title: Deletion of the Uracil Permease Gene Confers Cross-Resistance to 5-Fluorouracil and Azoles in Candida lusitaniae and Highlights Antagonistic Interaction between Fluorinated Nucleotides and Fluconazole

    doi: 10.1128/AAC.00009-14

    Figure Lengend Snippet: Resistance to fluconazole can be induced in other species of Candida using flucytosine, 5-fluorouracil, and 5-fluorouridine.

    Article Snippet: Stock solutions of 2 mg/ml fluconazole (ICN Biomedicals Inc.), 2 mg/ml flucytosine (Sigma), 2 mg/ml 5-fluorouracil (Sigma), and 2 mg/ml 5-fluorouridine (5FUI) were prepared in sterile distilled water.

    Techniques:

    Etest determination of the fluconazole MIC of the C. lusitaniae fur4 Δ and fur1 Δ mutant strains on RPMI medium supplemented with increasing concentrations of 5FU or left unsupplemented.

    Journal: Antimicrobial Agents and Chemotherapy

    Article Title: Deletion of the Uracil Permease Gene Confers Cross-Resistance to 5-Fluorouracil and Azoles in Candida lusitaniae and Highlights Antagonistic Interaction between Fluorinated Nucleotides and Fluconazole

    doi: 10.1128/AAC.00009-14

    Figure Lengend Snippet: Etest determination of the fluconazole MIC of the C. lusitaniae fur4 Δ and fur1 Δ mutant strains on RPMI medium supplemented with increasing concentrations of 5FU or left unsupplemented.

    Article Snippet: Stock solutions of 2 mg/ml fluconazole (ICN Biomedicals Inc.), 2 mg/ml flucytosine (Sigma), 2 mg/ml 5-fluorouracil (Sigma), and 2 mg/ml 5-fluorouridine (5FUI) were prepared in sterile distilled water.

    Techniques: Mutagenesis

    Growth of the antifungal-susceptible wild-type strain 6936 in RPMI supplemented with inhibitory concentrations of fluconazole along with various low concentrations of 5-fluorouracil (A) or flucytosine (B). Growth is given as a percentage of the growth

    Journal: Antimicrobial Agents and Chemotherapy

    Article Title: Deletion of the Uracil Permease Gene Confers Cross-Resistance to 5-Fluorouracil and Azoles in Candida lusitaniae and Highlights Antagonistic Interaction between Fluorinated Nucleotides and Fluconazole

    doi: 10.1128/AAC.00009-14

    Figure Lengend Snippet: Growth of the antifungal-susceptible wild-type strain 6936 in RPMI supplemented with inhibitory concentrations of fluconazole along with various low concentrations of 5-fluorouracil (A) or flucytosine (B). Growth is given as a percentage of the growth

    Article Snippet: Stock solutions of 2 mg/ml fluconazole (ICN Biomedicals Inc.), 2 mg/ml flucytosine (Sigma), 2 mg/ml 5-fluorouracil (Sigma), and 2 mg/ml 5-fluorouridine (5FUI) were prepared in sterile distilled water.

    Techniques:

    Growth of C. guilliermondii ATCC 6260, C. glabrata ATCC 90030, and C. tropicalis IP1275 in RPMI medium supplemented with inhibitory concentrations of fluconazole (4× the MIC for each strain) in the presence of different concentrations of the fluoropyrimidines

    Journal: Antimicrobial Agents and Chemotherapy

    Article Title: Deletion of the Uracil Permease Gene Confers Cross-Resistance to 5-Fluorouracil and Azoles in Candida lusitaniae and Highlights Antagonistic Interaction between Fluorinated Nucleotides and Fluconazole

    doi: 10.1128/AAC.00009-14

    Figure Lengend Snippet: Growth of C. guilliermondii ATCC 6260, C. glabrata ATCC 90030, and C. tropicalis IP1275 in RPMI medium supplemented with inhibitory concentrations of fluconazole (4× the MIC for each strain) in the presence of different concentrations of the fluoropyrimidines

    Article Snippet: Stock solutions of 2 mg/ml fluconazole (ICN Biomedicals Inc.), 2 mg/ml flucytosine (Sigma), 2 mg/ml 5-fluorouracil (Sigma), and 2 mg/ml 5-fluorouridine (5FUI) were prepared in sterile distilled water.

    Techniques:

    Growth of wild-type and ura3 Δ strains of C. lusitaniae in RMPI supplemented with 8 μg/ml fluconazole and different concentrations of 5FOA. Growth is expressed as the percentage of growth observed in inhibitor-free RPMI. The lack of bars

    Journal: Antimicrobial Agents and Chemotherapy

    Article Title: Deletion of the Uracil Permease Gene Confers Cross-Resistance to 5-Fluorouracil and Azoles in Candida lusitaniae and Highlights Antagonistic Interaction between Fluorinated Nucleotides and Fluconazole

    doi: 10.1128/AAC.00009-14

    Figure Lengend Snippet: Growth of wild-type and ura3 Δ strains of C. lusitaniae in RMPI supplemented with 8 μg/ml fluconazole and different concentrations of 5FOA. Growth is expressed as the percentage of growth observed in inhibitor-free RPMI. The lack of bars

    Article Snippet: Stock solutions of 2 mg/ml fluconazole (ICN Biomedicals Inc.), 2 mg/ml flucytosine (Sigma), 2 mg/ml 5-fluorouracil (Sigma), and 2 mg/ml 5-fluorouridine (5FUI) were prepared in sterile distilled water.

    Techniques:

    Resistance to fluconazole can be induced in other species of Candida using flucytosine, 5-fluorouracil, and 5-fluorouridine.

    Journal: Antimicrobial Agents and Chemotherapy

    Article Title: Deletion of the Uracil Permease Gene Confers Cross-Resistance to 5-Fluorouracil and Azoles in Candida lusitaniae and Highlights Antagonistic Interaction between Fluorinated Nucleotides and Fluconazole

    doi: 10.1128/AAC.00009-14

    Figure Lengend Snippet: Resistance to fluconazole can be induced in other species of Candida using flucytosine, 5-fluorouracil, and 5-fluorouridine.

    Article Snippet: Stock solutions of 2 mg/ml fluconazole (ICN Biomedicals Inc.), 2 mg/ml flucytosine (Sigma), 2 mg/ml 5-fluorouracil (Sigma), and 2 mg/ml 5-fluorouridine (5FUI) were prepared in sterile distilled water.

    Techniques: