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Cell annotation and different cell type distribution. (A) Cell type distribution for the scRNA sequence <t>data;</t> (B) Cell distribution between non-resistant and resistant groups; (C) Bubble plot of marker <t>gene</t> <t>expression</t> for each cell type; (D) Proportion of different cell types between resistant and non-resistant groups.
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Cell annotation and different cell type distribution. (A) Cell type distribution for the scRNA sequence <t>data;</t> (B) Cell distribution between non-resistant and resistant groups; (C) Bubble plot of marker <t>gene</t> <t>expression</t> for each cell type; (D) Proportion of different cell types between resistant and non-resistant groups.
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Cell annotation and different cell type distribution. (A) Cell type distribution for the scRNA sequence <t>data;</t> (B) Cell distribution between non-resistant and resistant groups; (C) Bubble plot of marker <t>gene</t> <t>expression</t> for each cell type; (D) Proportion of different cell types between resistant and non-resistant groups.
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Cell annotation and different cell type distribution. (A) Cell type distribution for the scRNA sequence <t>data;</t> (B) Cell distribution between non-resistant and resistant groups; (C) Bubble plot of marker <t>gene</t> <t>expression</t> for each cell type; (D) Proportion of different cell types between resistant and non-resistant groups.
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Cell annotation and different cell type distribution. (A) Cell type distribution for the scRNA sequence <t>data;</t> (B) Cell distribution between non-resistant and resistant groups; (C) Bubble plot of marker <t>gene</t> <t>expression</t> for each cell type; (D) Proportion of different cell types between resistant and non-resistant groups.
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Cell annotation and different cell type distribution. (A) Cell type distribution for the scRNA sequence <t>data;</t> (B) Cell distribution between non-resistant and resistant groups; (C) Bubble plot of marker <t>gene</t> <t>expression</t> for each cell type; (D) Proportion of different cell types between resistant and non-resistant groups.
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Cell annotation and different cell type distribution. (A) Cell type distribution for the scRNA sequence data; (B) Cell distribution between non-resistant and resistant groups; (C) Bubble plot of marker gene expression for each cell type; (D) Proportion of different cell types between resistant and non-resistant groups.

Journal: Frontiers in Immunology

Article Title: Integration of scRNA-seq and bulk RNA-seq to reveal the association and potential molecular mechanisms of metabolic reprogramming regulated by lactylation and chemotherapy resistance in ovarian cancer

doi: 10.3389/fimmu.2025.1513806

Figure Lengend Snippet: Cell annotation and different cell type distribution. (A) Cell type distribution for the scRNA sequence data; (B) Cell distribution between non-resistant and resistant groups; (C) Bubble plot of marker gene expression for each cell type; (D) Proportion of different cell types between resistant and non-resistant groups.

Article Snippet: Gene expression matrix data for single cell: the expression profiles of a single-cell dataset of OC were obtained from the Mendeley Data database ( ) ( https://data.mendeley.com/datasets/rc47y6m9mp/1 ), focusing on chemoresistant and non-resistant primary OC tissues.

Techniques: Sequencing, Marker, Gene Expression