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miR-495-3p inhibits GPX4 transcription by targeting ETS1

Journal: Molecular Biology Reports

Article Title: miR-495-3p promotes chronic obstructive pulmonary disease by activating ferroptosis in lung epithelial cells through regulation of the ETS1/GPX4 axis

doi: 10.1007/s11033-026-11820-z

Figure Lengend Snippet: miR-495-3p inhibits GPX4 transcription by targeting ETS1

Article Snippet: To investigate whether miR-495-3p inhibits GPX4 transcription by targeting ETS1, BEAS-2B cells were transfected with 50 nmol/L miR-495-3p agomir (HY-R01472A; MedChemExpress, USA) and incubated for 24 h, with NC agomir as a control, to detect the binding between miR-495-3p and ETS1.

Techniques:

Knockdown of miR-495-3p inhibits ferroptosis and alleviates COPD progression in mice by activating the ETS1/GPX4 pathway

Journal: Molecular Biology Reports

Article Title: miR-495-3p promotes chronic obstructive pulmonary disease by activating ferroptosis in lung epithelial cells through regulation of the ETS1/GPX4 axis

doi: 10.1007/s11033-026-11820-z

Figure Lengend Snippet: Knockdown of miR-495-3p inhibits ferroptosis and alleviates COPD progression in mice by activating the ETS1/GPX4 pathway

Article Snippet: To investigate whether miR-495-3p inhibits GPX4 transcription by targeting ETS1, BEAS-2B cells were transfected with 50 nmol/L miR-495-3p agomir (HY-R01472A; MedChemExpress, USA) and incubated for 24 h, with NC agomir as a control, to detect the binding between miR-495-3p and ETS1.

Techniques: Knockdown