Article Title: A Clinical Outcome of the Anti-PD-1 Therapy of Melanoma in Polish Patients Is Mediated by Population-Specific Gut Microbiome Composition
Figure Lengend Snippet: The inflammatory state of gut mucosa was evaluated by calprotectin concentration measurement in the stool of study participants. Comparison between groups of controls (C) and the anti-PD-1 recipients before the first injection of the ICI therapeutics, classified as responders (R) and non-responders (NR) according to the clinical outcome of ICI therapy. The p -values describing the statistical significance of the calprotectin level in the study groups were calculated with Wilcoxon Rank Sum Test. The plot is in a logarithmic scale.
Article Snippet: Additionally, 15 mg of raw fecal samples was collected, and calprotectin concentration in stool was measured with IDK Calprotectin ELISA Kit (Immundiagnostik AG, Bensheim, Germany), according with the instructions of the kit manual.
Techniques: Concentration Assay, Injection