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Cayman Chemical doxorubicin hydrochloride dox hcl
Doxorubicin Hydrochloride Dox Hcl, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/doxorubicin hydrochloride dox hcl/product/Cayman Chemical
Average 92 stars, based on 1 article reviews
Price from $9.99 to $1999.99
doxorubicin hydrochloride dox hcl - by Bioz Stars, 2020-04
92/100 stars

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Multiple Displacement Amplification:

Article Title: Cholecalciferol-PEG Conjugate Based Nanomicelles of Doxorubicin for Treatment of Triple-Negative Breast Cancer
Article Snippet: Cholecalciferol (vitamin D3 ), poly(ethylene glycol) methyl ether (average Mn ~ 2000) (mPEG), glutaric anhydride, 4-dimethylaminopyridine (DMAP), N -hydroxysuccinimide (NHS), dicyclohexylcarbodiimide (DCC), triethylamine (TEA), and doxorubicin hydrochloride (DOX.HCl) were purchased from Cayman Chemical Company (MI, USA). .. The cell lines MCF10A, MDA-MB-468, and MDA-MB-231 were purchased from ATCC (Manassas, VA).

Modification:

Article Title: Cholecalciferol-PEG Conjugate Based Nanomicelles of Doxorubicin for Treatment of Triple-Negative Breast Cancer
Article Snippet: Cholecalciferol (vitamin D3 ), poly(ethylene glycol) methyl ether (average Mn ~ 2000) (mPEG), glutaric anhydride, 4-dimethylaminopyridine (DMAP), N -hydroxysuccinimide (NHS), dicyclohexylcarbodiimide (DCC), triethylamine (TEA), and doxorubicin hydrochloride (DOX.HCl) were purchased from Cayman Chemical Company (MI, USA). .. The cell lines were cultured in Dulbecco’s modified Eagle’s medium (DMEM)/F-12 and supplemented with 10% fetal bovine serum (FBS) and antibiotic mixture of penicillin streptomycin and neomycin.

Droplet Countercurrent Chromatography:

Article Title: Cholecalciferol-PEG Conjugate Based Nanomicelles of Doxorubicin for Treatment of Triple-Negative Breast Cancer
Article Snippet: .. Cholecalciferol (vitamin D3 ), poly(ethylene glycol) methyl ether (average Mn ~ 2000) (mPEG), glutaric anhydride, 4-dimethylaminopyridine (DMAP), N -hydroxysuccinimide (NHS), dicyclohexylcarbodiimide (DCC), triethylamine (TEA), and doxorubicin hydrochloride (DOX.HCl) were purchased from Cayman Chemical Company (MI, USA). .. Rhodamine 123 dichloromethane (DCM), chloroform, methanol, ethyl acetate, and petroleum ether (60:40) were purchased from Sigma-Aldrich, (St. Louis, MO).

Cell Culture:

Article Title: Cholecalciferol-PEG Conjugate Based Nanomicelles of Doxorubicin for Treatment of Triple-Negative Breast Cancer
Article Snippet: Cholecalciferol (vitamin D3 ), poly(ethylene glycol) methyl ether (average Mn ~ 2000) (mPEG), glutaric anhydride, 4-dimethylaminopyridine (DMAP), N -hydroxysuccinimide (NHS), dicyclohexylcarbodiimide (DCC), triethylamine (TEA), and doxorubicin hydrochloride (DOX.HCl) were purchased from Cayman Chemical Company (MI, USA). .. The cell lines were cultured in Dulbecco’s modified Eagle’s medium (DMEM)/F-12 and supplemented with 10% fetal bovine serum (FBS) and antibiotic mixture of penicillin streptomycin and neomycin.

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    Cayman Chemical instruments doxorubicin hydrochloride dox hcl
    Light templated <t>doxorubicin</t> delivery in vitro. Patterned light (365 nm, 15–17 mW/cm 2 ) activation of 1 (300 μM) and cellular uptake of DOX ( red ).
    Instruments Doxorubicin Hydrochloride Dox Hcl, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 91/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/instruments doxorubicin hydrochloride dox hcl/product/Cayman Chemical
    Average 91 stars, based on 2 article reviews
    Price from $9.99 to $1999.99
    instruments doxorubicin hydrochloride dox hcl - by Bioz Stars, 2020-04
    91/100 stars
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    Light templated doxorubicin delivery in vitro. Patterned light (365 nm, 15–17 mW/cm 2 ) activation of 1 (300 μM) and cellular uptake of DOX ( red ).

    Journal: International Journal of Molecular Sciences

    Article Title: Spatiotemporal Control of Doxorubicin Delivery from “Stealth-Like” Prodrug Micelles

    doi: 10.3390/ijms18102033

    Figure Lengend Snippet: Light templated doxorubicin delivery in vitro. Patterned light (365 nm, 15–17 mW/cm 2 ) activation of 1 (300 μM) and cellular uptake of DOX ( red ).

    Article Snippet: Materials and Instruments Doxorubicin hydrochloride (DOX·HCl) was purchased from Cayman Chemical Company (Ann Arbor, MI, USA) and used without further purification.

    Techniques: In Vitro, Activation Assay

    Viability of HeLa cells in vitro treated with doxorubicin pro-drug micelles. ( a ) Cell viability following incubation with varying concentrations (10 nM–100 μM) of free DOX ( black ) and 1 ( red ) in the absence of light; ( b ) Viability of HeLa cells in vitro treated with varying concentrations of 1 and irradiated (365 nm, 15–17 mW/cm 2 ) for up to 1h. Pink line corresponds to photoinduced cytotoxicity.

    Journal: International Journal of Molecular Sciences

    Article Title: Spatiotemporal Control of Doxorubicin Delivery from “Stealth-Like” Prodrug Micelles

    doi: 10.3390/ijms18102033

    Figure Lengend Snippet: Viability of HeLa cells in vitro treated with doxorubicin pro-drug micelles. ( a ) Cell viability following incubation with varying concentrations (10 nM–100 μM) of free DOX ( black ) and 1 ( red ) in the absence of light; ( b ) Viability of HeLa cells in vitro treated with varying concentrations of 1 and irradiated (365 nm, 15–17 mW/cm 2 ) for up to 1h. Pink line corresponds to photoinduced cytotoxicity.

    Article Snippet: Materials and Instruments Doxorubicin hydrochloride (DOX·HCl) was purchased from Cayman Chemical Company (Ann Arbor, MI, USA) and used without further purification.

    Techniques: In Vitro, Incubation, Irradiation

    Characterization of doxorubicin pro-drug micelles and light induced drug release. ( a ) TEM (transmission electron microscopy) image (uranyl acetate stain) of micelles of 1 (300 μM, approx. 0.7 mg/mL); ( b ) Time evolution of the HPLC (high-performance liquid chromatography) spectra of a solution of 1 (100 μM in PBS (phosphate buffered saline)) during photolysis (365 nm, 3–5 mW/cm 2 ). Free DOX (100 μM), dissolved in PBS, was used to confirm clean photolysis of 1 to release “active” DOX. HPLC conditions described in Materials and Methods; ( c ) CMC (critical micelle concentration) determination by light scattering following serial dilution of 1 (100 μM–75 nM) in PBS; ( d ) In vitro DOX release profiles from 1 (300 μM) in PBS. No UV irradiation ( red ), UV irradiation at 9 h ( black ) and free DOX control ( blue ).

    Journal: International Journal of Molecular Sciences

    Article Title: Spatiotemporal Control of Doxorubicin Delivery from “Stealth-Like” Prodrug Micelles

    doi: 10.3390/ijms18102033

    Figure Lengend Snippet: Characterization of doxorubicin pro-drug micelles and light induced drug release. ( a ) TEM (transmission electron microscopy) image (uranyl acetate stain) of micelles of 1 (300 μM, approx. 0.7 mg/mL); ( b ) Time evolution of the HPLC (high-performance liquid chromatography) spectra of a solution of 1 (100 μM in PBS (phosphate buffered saline)) during photolysis (365 nm, 3–5 mW/cm 2 ). Free DOX (100 μM), dissolved in PBS, was used to confirm clean photolysis of 1 to release “active” DOX. HPLC conditions described in Materials and Methods; ( c ) CMC (critical micelle concentration) determination by light scattering following serial dilution of 1 (100 μM–75 nM) in PBS; ( d ) In vitro DOX release profiles from 1 (300 μM) in PBS. No UV irradiation ( red ), UV irradiation at 9 h ( black ) and free DOX control ( blue ).

    Article Snippet: Materials and Instruments Doxorubicin hydrochloride (DOX·HCl) was purchased from Cayman Chemical Company (Ann Arbor, MI, USA) and used without further purification.

    Techniques: Transmission Electron Microscopy, Transmission Assay, Electron Microscopy, Staining, High Performance Liquid Chromatography, Concentration Assay, Serial Dilution, In Vitro, Irradiation

    Light activated doxorubicin pro-drug micelles. ( a ) Doxorubicin- ortho -nitrobenzyl-mPEG 2000 construct, 1 ; ( b ) Self-assembly of 1 in aqueous media to 100 nm PEGylated and DOX (doxorubicin)-rich micelles from which quantitative drug release is triggered by light; ( c ) Light directed DOX release, cell uptake, and cell death.

    Journal: International Journal of Molecular Sciences

    Article Title: Spatiotemporal Control of Doxorubicin Delivery from “Stealth-Like” Prodrug Micelles

    doi: 10.3390/ijms18102033

    Figure Lengend Snippet: Light activated doxorubicin pro-drug micelles. ( a ) Doxorubicin- ortho -nitrobenzyl-mPEG 2000 construct, 1 ; ( b ) Self-assembly of 1 in aqueous media to 100 nm PEGylated and DOX (doxorubicin)-rich micelles from which quantitative drug release is triggered by light; ( c ) Light directed DOX release, cell uptake, and cell death.

    Article Snippet: Materials and Instruments Doxorubicin hydrochloride (DOX·HCl) was purchased from Cayman Chemical Company (Ann Arbor, MI, USA) and used without further purification.

    Techniques: Construct