Journal: Insights into Imaging

Article Title: Digitized and structured informed patient consent before contrast-enhanced computed tomography: feasibility and benefits in clinical routine

doi: 10.1186/s13244-022-01304-6

Figure Lengend Snippet: Cost–benefit analysis for digitized versus conventional informed patient consent (D-IPC vs C-IPC)

Article Snippet: The front desk in the radiology department allocated the contrast-enhanced CT questionnaires to the present patients using a desktop application of the D-IPC software (MEDePORT, Thieme Compliance GmbH, Erlangen, Germany).

Techniques: Software

Journal: Food Science & Nutrition

Article Title: Listeria monocytogenes in foods—From culture identification to whole‐genome characteristics

doi: 10.1002/fsn3.2910

Figure Lengend Snippet: Advantages and limitations of methods used for L. monocytogenes typing

Article Snippet: Furthermore, a commonly used bioinformatics desktop software application BioNumerics developed by Applied Maths allows to produce high‐quality, reproducible results.

Techniques: Bioprocessing, Multiplex Assay, Amplification, Sequencing

Journal: Cancer Medicine

Article Title: METTL3 expression is associated with glycolysis metabolism and sensitivity to glycolytic stress in hepatocellular carcinoma

doi: 10.1002/cam4.2918

Figure Lengend Snippet: METTL3 expression was associated with altered glucose metabolism in HCC cases. A, Illustration of enzymes involved the key steps in glucose metabolic flux. B, Heatmap with cluster analysis of METT3 expression and glucose metabolism related genes revealed a co‐expression trend between METTL3 and genes involved in glycolysis. C, D, GSEA plot of two predefined gene sets based on the METTL3 expression revealed genes involved in normal glucose metabolism were significantly enriched in HCC cases with lower METTL3 expression, which suggesting that normal glucose metabolism was preserved in these cases. E, A heatmap displaying the Spearman rank correlation test results which implied positive correlation between METTL3 expression and glycolysis‐related genes and negative correlation between METTL3 expression and glycogenesis‐related genes, the bar indicates the value of spearman correlation coefficient

Article Snippet: Java GSEA Desktop Application software (V3.0, Broad Institute) was used.

Techniques: Expressing

Journal: Cancer Medicine

Article Title: METTL3 expression is associated with glycolysis metabolism and sensitivity to glycolytic stress in hepatocellular carcinoma

doi: 10.1002/cam4.2918

Figure Lengend Snippet: Correlation between METTL3 expression and activity of mTORC1 activity. A, GSEA plot of mTOR signal pathway based on METTL3 expression levels in TCGA cases. B, HCC cell lines were treated with siRNA oligonucleotides or not, then the indicated proteins were detected by WB. (C‐G) The HCC cell lines were treated with rapamycin or co‐treated with siRNA oligonucleotides, for 48 h followed by immunoblotting for mTOR phosphorylation levels (C), glucose uptake assays in HCC cells Huh‐7 (D) and SMMC‐7721 (E), and lactate production assays in Huh‐7 cell line (F) and SMMC‐7721 cell line (G). H, I, Gene‐specific m6A‐IP‐qPCR results showing the relative methylation levels of five RNAs in the HCC cell lines treated with siRNA oligonucleotides compared to those normal control cells

Article Snippet: Java GSEA Desktop Application software (V3.0, Broad Institute) was used.

Techniques: Expressing, Activity Assay, Western Blot, Phospho-proteomics, Methylation, Control

Journal: Scientific Reports

Article Title: Transcriptome analysis suggests a compensatory role of the cofactors coenzyme A and NAD + in medium-chain acyl-CoA dehydrogenase knockout mice

doi: 10.1038/s41598-019-50758-0

Figure Lengend Snippet: Up- and downregulated metabolic gene sets in KO compared to WT based on the GSEA method.

Article Snippet: Gene-set enrichment analysis (GSEA) was performed according to Subramanian et al . 2005 using the GSEA desktop Java application software (version 2.2.4, Broad Institute).

Techniques: Phospho-proteomics

Journal: Scientific Reports

Article Title: Transcriptome analysis suggests a compensatory role of the cofactors coenzyme A and NAD + in medium-chain acyl-CoA dehydrogenase knockout mice

doi: 10.1038/s41598-019-50758-0

Figure Lengend Snippet: Up- and downregulated metabolic gene sets in KO compared to WT based on the Alternative GSEA method.

Article Snippet: Gene-set enrichment analysis (GSEA) was performed according to Subramanian et al . 2005 using the GSEA desktop Java application software (version 2.2.4, Broad Institute).

Techniques: