rabbit polyclonal anti d1 receptor (Alomone Labs)


Structured Review
Rabbit Polyclonal Anti D1 Receptor, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit polyclonal anti d1 receptor/product/Alomone Labs
Average 94 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
rabbit polyclonal anti d1 receptor (Alomone Labs)


Structured Review
Rabbit Polyclonal Anti D1 Receptor, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit polyclonal anti d1 receptor/product/Alomone Labs
Average 94 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
d1r rabbit polyclonal adr (Alomone Labs)


Structured Review

D1r Rabbit Polyclonal Adr, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/d1r rabbit polyclonal adr/product/Alomone Labs
Average 94 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons"
Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons
Journal: Cerebral Cortex (New York, NY)
doi: 10.1093/cercor/bhz078

Figure Legend Snippet: Antibody information
Techniques Used:

Figure Legend Snippet: Proportion of neurons expressing dopamine receptors across cortical layers. (A) The density of different neuronal classes across cortical layers. (B) The density of neurons expressing D1Rs or D2Rs for each cortical layer. (C) D1R and D2R expression across FEF cortex. Tissue is from the same animal (Monkey 4) and is oriented with the pial surface at the top and white matter at the bottom. Scale bar = 100 μm.
Techniques Used: Expressing

Figure Legend Snippet: Proportion of neurogranin+ and SMI-32+ pyramidal neurons that express D1Rs or D2Rs. Significantly more neurogranin+ neurons and SMI-32+ neurons express D1Rs (black) than D2Rs (gray). *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts (Neurogranin+ N = 3028, P < 10−10; SMI32+ N = 225, P = 3.2 × 10−13). Bar heights and standard error bars are calculated from the across-animal mean proportions, and the exact values are described in the main text. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.
Techniques Used:

Figure Legend Snippet: Distribution of dopamine receptors in pyramidal neuron populations across cortical layers. (A) The proportion of D1R-expressing neurogranin+ pyramidal neurons is larger than the proportion of D2R-expressing neurogranin+ neurons across all layers. This difference was statistically significant in layers II–V. Overall, the ratio of D1Rs to D2Rs decreases across cortical layers (right y-axis). (B) The proportion of D1R-expressing SMI-32+ pyramidal neurons is also larger than the proportion of D2R-expressing SMI-32+ neurons across all layers. This difference was statistically significant in layers II-III, and VI. *, **, and *** denote significance at the level of 0.05, 0.01, and 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Neurogranin+ N = 766, 111, 262, 575; P < 10−16, 0.0048, 9.39 × 10−8, 1.6 × 10−4 for layers II-III, IV, V, and VI, respectively. SMI-32+ N = 72, 31, 35, 73; P = 0.0023, 0.2, 0.09, and 0.0019 for layers II-III, IV, V, and VI respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table Table4.4. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.
Techniques Used: Expressing

Figure Legend Snippet: P -values of layer-versus-layer pairwise comparisons for D1R and D2R expression on different neuronal classes
Techniques Used: Expressing

Figure Legend Snippet: Proportion of inhibitory interneuron classes that express D1Rs or D2Rs. A significantly higher proportion of parvalbumin+ inhibitory interneurons express D2Rs than D1Rs. A significantly higher proportion of calbindin+ inhibitory interneurons express D1Rs compared with D2Rs. When pooling across interneuron classes, the proportion of D2R-expressing interneurons is significantly greater than the proportion of D1R-expressing interneurons. We did not perform a statistical comparison between D1R- and D2R-expressing somatostatin+ neurons because they were so rare. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determine using chi-squared tests calculated on total counts (Parvalbumin+ N = 635, P < 10−16; Calbindin+ N = 624, P = 5.7 × 10−5; Calretinin+ N = 648, P = 0.42). Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4; Somatostatin+ D1R, D2R = 3, 4.
Techniques Used: Expressing

Figure Legend Snippet: Distribution of dopamine receptors across inhibitory neuron populations across cortical layers. (A) Across all layers, the proportion of D2R-expressing parvalbumin+ neurons is higher than the proportion of D1R-expressing parvalbumin+ neurons. (B) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calbindin+ neurons across layers. (C) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calretinin+ neurons across layers. Significance was determined using chi-squared tests calculated on total counts. Parvalbumin+ N = 197, 44, 88, 75; P = 1.98 × 10−7, 3.89 × 10−5, 1.36 × 10−10, 4.65 × 10−9 for layers II, III, IV, V, and VI, respectively. Calbindin+ N = 232, 34, 46, 70; P = 0.64, 0.46, 0.61, 0.31 for layers II, III, IV, V, and VI, respectively. Calretinin+ N = 352, 31, 41, 52; P = 5.04 × 10−4, 0.42, 0.87, and 0.27 for layers II, III, IV, V, and VI, respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table Table4.4. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4.
Techniques Used: Expressing

Figure Legend Snippet: Relative proportion of D1R- and D2R-expressing visual cortex-projecting FEF neurons. The left panel shows the proportion of the 2 populations (V4-projecting and MT-projecting) of neurons that express either D1Rs or D2Rs. The top-right panel shows the proportion of MT-projecting neurons that express either D1Rs or D2Rs. The lower-right panel shows the proportion of V4-projecting FEF neurons that express either D1Rs or D2Rs. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Ns displayed on the bars. Combined P < 10−16, MT-projecting P < 10−16, V4-projecting P = 5 × 10−4. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text (N = 3 for all comparisons).
Techniques Used: Expressing
d1r rabbit polyclonal adr (Alomone Labs)


Structured Review

D1r Rabbit Polyclonal Adr, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/d1r rabbit polyclonal adr/product/Alomone Labs
Average 94 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons"
Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons
Journal: Cerebral Cortex (New York, NY)
doi: 10.1093/cercor/bhz078

Figure Legend Snippet: Antibody information
Techniques Used:

Figure Legend Snippet: Proportion of neurons expressing dopamine receptors across cortical layers. (A) The density of different neuronal classes across cortical layers. (B) The density of neurons expressing D1Rs or D2Rs for each cortical layer. (C) D1R and D2R expression across FEF cortex. Tissue is from the same animal (Monkey 4) and is oriented with the pial surface at the top and white matter at the bottom. Scale bar = 100 μm.
Techniques Used: Expressing

Figure Legend Snippet: Proportion of neurogranin+ and SMI-32+ pyramidal neurons that express D1Rs or D2Rs. Significantly more neurogranin+ neurons and SMI-32+ neurons express D1Rs (black) than D2Rs (gray). *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts (Neurogranin+ N = 3028, P < 10−10; SMI32+ N = 225, P = 3.2 × 10−13). Bar heights and standard error bars are calculated from the across-animal mean proportions, and the exact values are described in the main text. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.
Techniques Used:

Figure Legend Snippet: Distribution of dopamine receptors in pyramidal neuron populations across cortical layers. (A) The proportion of D1R-expressing neurogranin+ pyramidal neurons is larger than the proportion of D2R-expressing neurogranin+ neurons across all layers. This difference was statistically significant in layers II–V. Overall, the ratio of D1Rs to D2Rs decreases across cortical layers (right y-axis). (B) The proportion of D1R-expressing SMI-32+ pyramidal neurons is also larger than the proportion of D2R-expressing SMI-32+ neurons across all layers. This difference was statistically significant in layers II-III, and VI. *, **, and *** denote significance at the level of 0.05, 0.01, and 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Neurogranin+ N = 766, 111, 262, 575; P < 10−16, 0.0048, 9.39 × 10−8, 1.6 × 10−4 for layers II-III, IV, V, and VI, respectively. SMI-32+ N = 72, 31, 35, 73; P = 0.0023, 0.2, 0.09, and 0.0019 for layers II-III, IV, V, and VI respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table Table4.4. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.
Techniques Used: Expressing

Figure Legend Snippet: P -values of layer-versus-layer pairwise comparisons for D1R and D2R expression on different neuronal classes
Techniques Used: Expressing

Figure Legend Snippet: Proportion of inhibitory interneuron classes that express D1Rs or D2Rs. A significantly higher proportion of parvalbumin+ inhibitory interneurons express D2Rs than D1Rs. A significantly higher proportion of calbindin+ inhibitory interneurons express D1Rs compared with D2Rs. When pooling across interneuron classes, the proportion of D2R-expressing interneurons is significantly greater than the proportion of D1R-expressing interneurons. We did not perform a statistical comparison between D1R- and D2R-expressing somatostatin+ neurons because they were so rare. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determine using chi-squared tests calculated on total counts (Parvalbumin+ N = 635, P < 10−16; Calbindin+ N = 624, P = 5.7 × 10−5; Calretinin+ N = 648, P = 0.42). Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4; Somatostatin+ D1R, D2R = 3, 4.
Techniques Used: Expressing

Figure Legend Snippet: Distribution of dopamine receptors across inhibitory neuron populations across cortical layers. (A) Across all layers, the proportion of D2R-expressing parvalbumin+ neurons is higher than the proportion of D1R-expressing parvalbumin+ neurons. (B) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calbindin+ neurons across layers. (C) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calretinin+ neurons across layers. Significance was determined using chi-squared tests calculated on total counts. Parvalbumin+ N = 197, 44, 88, 75; P = 1.98 × 10−7, 3.89 × 10−5, 1.36 × 10−10, 4.65 × 10−9 for layers II, III, IV, V, and VI, respectively. Calbindin+ N = 232, 34, 46, 70; P = 0.64, 0.46, 0.61, 0.31 for layers II, III, IV, V, and VI, respectively. Calretinin+ N = 352, 31, 41, 52; P = 5.04 × 10−4, 0.42, 0.87, and 0.27 for layers II, III, IV, V, and VI, respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table Table4.4. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4.
Techniques Used: Expressing

Figure Legend Snippet: Relative proportion of D1R- and D2R-expressing visual cortex-projecting FEF neurons. The left panel shows the proportion of the 2 populations (V4-projecting and MT-projecting) of neurons that express either D1Rs or D2Rs. The top-right panel shows the proportion of MT-projecting neurons that express either D1Rs or D2Rs. The lower-right panel shows the proportion of V4-projecting FEF neurons that express either D1Rs or D2Rs. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Ns displayed on the bars. Combined P < 10−16, MT-projecting P < 10−16, V4-projecting P = 5 × 10−4. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text (N = 3 for all comparisons).
Techniques Used: Expressing
rabbit polyclonal anti d1r (Alomone Labs)


Structured Review
Rabbit Polyclonal Anti D1r, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit polyclonal anti d1r/product/Alomone Labs
Average 94 stars, based on 1 article reviews
Price from $9.99 to $1999.99