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Journal: PLoS Computational Biology
Article Title: PSAMM: A Portable System for the Analysis of Metabolic Models
doi: 10.1371/journal.pcbi.1004732
Figure Lengend Snippet: The running time for both the PSAMM overall function (blue) and the PSAMM problem-solving steps (red) were calculated, and the running time for COBRA only included the problem-solving step (green). Each value represents a median of seven simulation runs using the same specifications, and the error bars indicate the 25th and the 75th percentiles.
Article Snippet: The simulations were carried out on the model iJO1366 [ ] with the
Techniques: Combined Bisulfite Restriction Analysis Assay
Journal: PLoS Computational Biology
Article Title: PSAMM: A Portable System for the Analysis of Metabolic Models
doi: 10.1371/journal.pcbi.1004732
Figure Lengend Snippet: The five main components include: (1) user interface, (2) model input/output, (3) model representation, (4) linear programming utilities, and (5) model checking/simulation. Connections among these components form the internal workflow of PSAMM.
Article Snippet: The simulations were carried out on the model iJO1366 [ ] with the
Techniques:
Journal: PLoS Computational Biology
Article Title: PSAMM: A Portable System for the Analysis of Metabolic Models
doi: 10.1371/journal.pcbi.1004732
Figure Lengend Snippet: List of commands supported in the psamm-model program. Additional parameters can be specified for the commands, for example to select a specific implementation among multiple algorithms, enable/disable thermodynamic constraints, or select linear programming solvers, etc . Details about these parameters are available through the -h or -- help options for each command.
Article Snippet: The simulations were carried out on the model iJO1366 [ ] with the
Techniques:
Journal: PLoS Computational Biology
Article Title: PSAMM: A Portable System for the Analysis of Metabolic Models
doi: 10.1371/journal.pcbi.1004732
Figure Lengend Snippet: (a) This diagram shows an example of the YAML model format, which includes a central model definition (model.yaml) and multiple annotation files. Each box indicates a file with a possible filename indicated above the box, and the text within is a snapshot of the file content. (b) An example showing how changes can be tracked in a PSAMM YAML file (biomass.yaml) using the Git version control system in command line. The text highlighted in red indicates the stoichiometry of the compound arg-L in an old version of the biomass function, while the text highlighted in green indicates the updated value in a new version of the model. Additional examples of applying Git version control on the YAML format are provided in the supplemental materials ( – Texts).
Article Snippet: The simulations were carried out on the model iJO1366 [ ] with the
Techniques: Control