Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Bateman 2010a

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Medications, Clinical Proteomics, Sequencing, Selection

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Bateman 2010b

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Beeh 2006

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Infection, Medications, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Brusasco 2003

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Infection, Medications, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Casaburi 2002

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Sequencing, Selection, Generated, Capsules

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Chan 2007

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Infection, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Cooper 2010

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Modification, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Covelli 2005

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Infection, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Dusser 2006

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Infection, Medications, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Freeman 2007

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Infection, Sequencing, Selection, Generated

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Johansson 2008

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Infection, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Magnussen 2008

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Moita 2008

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Infection, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: NCT00144326

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Activity Assay, Plasmid Preparation, Modification, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Niewoehner 2005

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Medications, Sequencing, Selection, Generated

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Powrie 2007

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Concentration Assay, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Tashkin 2008

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Infection, Medications, Sequencing, Selection, Generated

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Tonnel 2008

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Infection, Sequencing, Selection, Blocking Assay, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Trooster 2011

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Medications, Activity Assay, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Verkinde 2006

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Infection, Modification, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Tiotropium versus placebo for chronic obstructive pulmonary disease

doi: 10.1002/14651858.CD009285.pub3

Figure Lengend Snippet: Voshaar 2008

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time.

Techniques: Biomarker Discovery, Sequencing, Selection, Generated

Journal: The Cochrane Database of Systematic Reviews

Article Title: Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a network meta‐analysis

doi: 10.1002/14651858.CD010844.pub2

Figure Lengend Snippet: Bateman 2010a

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time..

Techniques: Medications, Sequencing, Selection

Journal: The Cochrane Database of Systematic Reviews

Article Title: Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a network meta‐analysis

doi: 10.1002/14651858.CD010844.pub2

Figure Lengend Snippet: Brusasco 2003

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time..

Techniques: Infection, Medications, Sequencing, Selection, Generated, Control

Journal: The Cochrane Database of Systematic Reviews

Article Title: Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a network meta‐analysis

doi: 10.1002/14651858.CD010844.pub2

Figure Lengend Snippet: Calverley 2007 [TORCH]

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time..

Techniques: Western Blot, Biomarker Discovery, Solvent, Medications, Sequencing, Selection, Generated, Clinical Proteomics

Journal: The Cochrane Database of Systematic Reviews

Article Title: Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a network meta‐analysis

doi: 10.1002/14651858.CD010844.pub2

Figure Lengend Snippet: Niewoehner 2005

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time..

Techniques: Biomarker Discovery, Medications, Sequencing, Selection, Generated, Modification

Journal: The Cochrane Database of Systematic Reviews

Article Title: Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a network meta‐analysis

doi: 10.1002/14651858.CD010844.pub2

Figure Lengend Snippet: Ohar 2013

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time..

Techniques: Sequencing, Selection

Journal: The Cochrane Database of Systematic Reviews

Article Title: Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a network meta‐analysis

doi: 10.1002/14651858.CD010844.pub2

Figure Lengend Snippet: Ozol 2005

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time..

Techniques: Sequencing, Selection, Generated

Journal: The Cochrane Database of Systematic Reviews

Article Title: Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a network meta‐analysis

doi: 10.1002/14651858.CD010844.pub2

Figure Lengend Snippet: Renkema 1996

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time..

Techniques: Biomarker Discovery, Functional Assay, Clinical Proteomics, Sequencing, Selection

Journal: The Cochrane Database of Systematic Reviews

Article Title: Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a network meta‐analysis

doi: 10.1002/14651858.CD010844.pub2

Figure Lengend Snippet: Schermer 2009

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time..

Techniques: Sequencing, Selection, Generated, Blocking Assay

Journal: The Cochrane Database of Systematic Reviews

Article Title: Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a network meta‐analysis

doi: 10.1002/14651858.CD010844.pub2

Figure Lengend Snippet: Tashkin 2008a [UPLIFT]

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time..

Techniques: Biomarker Discovery, Infection, Medications, Sequencing, Selection

Journal: The Cochrane Database of Systematic Reviews

Article Title: Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a network meta‐analysis

doi: 10.1002/14651858.CD010844.pub2

Figure Lengend Snippet: Tonnel 2008 [TIPHON]

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time..

Techniques: Biomarker Discovery, Infection, Sequencing, Selection, Blocking Assay

Journal: The Cochrane Database of Systematic Reviews

Article Title: Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a network meta‐analysis

doi: 10.1002/14651858.CD010844.pub2

Figure Lengend Snippet: Vogelmeier 2011 [POET]

Article Snippet: Random sequence generation (selection bias) , Low risk , Treatment allocation was determined by a computer‐generated randomisation code provided by Boehringer Ingelheim. Randomisation was stratified by study centre and within centres, and performed in blocks to ensure balanced distribution of the treatment groups at any time..

Techniques: Biomarker Discovery, Infection, Medications, Sequencing, Selection, Generated, Blocking Assay, Capsules