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Current and former human FPR family receptor nomenclature and their agonists

Journal: British Journal of Pharmacology

Article Title: Formylpeptide receptor 2: Nomenclature, structure, signalling and translational perspectives: IUPHAR review 35

doi: 10.1111/bph.15919

Figure Lengend Snippet: Current and former human FPR family receptor nomenclature and their agonists

Article Snippet: Coronary artery occlusion with reperfusion (male Sprague Dawley rats) , Cmpd43 oral gavage , ↑ viable LV myocardium, ↓ LV dilatation, preserved LV function.

Techniques:

Selected diseases identified as amenable to FPR2‐targeted intervention in vivo to date

Journal: British Journal of Pharmacology

Article Title: Formylpeptide receptor 2: Nomenclature, structure, signalling and translational perspectives: IUPHAR review 35

doi: 10.1111/bph.15919

Figure Lengend Snippet: Selected diseases identified as amenable to FPR2‐targeted intervention in vivo to date

Article Snippet: Coronary artery occlusion with reperfusion (male Sprague Dawley rats) , Cmpd43 oral gavage , ↑ viable LV myocardium, ↓ LV dilatation, preserved LV function.

Techniques: In Vivo, Adjuvant, Activation Assay, Gene Expression, Expressing, Clinical Proteomics, Control

The effects of the test compounds and FPR peptide agonists on the LPS-induced NF-κB activity in human THP1-Blue cells, cytotoxicity, and Ca 2+ mobilization in FPR1/FPR2-transfected HL-60 cells.

Journal: Molecules

Article Title: Pyridazinones and Structurally Related Derivatives with Anti-Inflammatory Activity

doi: 10.3390/molecules27123749

Figure Lengend Snippet: The effects of the test compounds and FPR peptide agonists on the LPS-induced NF-κB activity in human THP1-Blue cells, cytotoxicity, and Ca 2+ mobilization in FPR1/FPR2-transfected HL-60 cells.

Article Snippet: Cmpd43 (TC-FPR 43) and Boc-MLF were purchased from Tocris Biosciences (Bristol, UK).

Techniques: Activity Assay, Inhibition

Journal: eLife

Article Title: Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs

doi: 10.7554/eLife.74101

Figure Lengend Snippet:

Article Snippet: Chemical compound, drug , Cmpd43 , Provided by Bristol-Myers Squibb , N/A , .

Techniques: Functional Assay, Transfection, Construct, Plasmid Preparation, Software, Inverted Microscopy