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Mechanisms of action of cirRNA: (A) CircRNAs have the capability to directly interact with transcription complexes, thereby influencing the expression of parental genes. (B) CircRNAs have the ability to act as miRNA sponges. (C) circRNAs can interact with <t>circRNA</t> binding proteins (cRBPs) modulate their functions. (D) CircRNAs have the ability to encode peptides and proteins.
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Comprehensive ceRNA Interaction Networks and Regulatory Axes in GBM. A <t>circRNA/lncRNA–miRNA–mRNA</t> interaction network, illustrating the competitive binding relationships between ncRNAs and mRNAs. The size and color of the nodes represent the strength of interaction and their centrality within the network, respectively. B Regulatory axis network of circRNAs, illustrating the routes of circRNA-mediated control, from circRNAs to miRNAs and on to their mRNA targets. C Regulatory axis network of lncRNAs, outlining specific pathways of regulation from lncRNAs, through miRNAs, to their mRNA targets (color figure online)
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Image Search Results


Mechanisms of action of cirRNA: (A) CircRNAs have the capability to directly interact with transcription complexes, thereby influencing the expression of parental genes. (B) CircRNAs have the ability to act as miRNA sponges. (C) circRNAs can interact with circRNA binding proteins (cRBPs) modulate their functions. (D) CircRNAs have the ability to encode peptides and proteins.

Journal: Frontiers in Cellular and Infection Microbiology

Article Title: Recent progress in tuberculosis diagnosis: insights into blood-based biomarkers and emerging technologies

doi: 10.3389/fcimb.2025.1567592

Figure Lengend Snippet: Mechanisms of action of cirRNA: (A) CircRNAs have the capability to directly interact with transcription complexes, thereby influencing the expression of parental genes. (B) CircRNAs have the ability to act as miRNA sponges. (C) circRNAs can interact with circRNA binding proteins (cRBPs) modulate their functions. (D) CircRNAs have the ability to encode peptides and proteins.

Article Snippet: circRNA , 2018 , hsa_circ_0001953; hsa_circ_0009024 , Plasma , aTB vs HC , Arraystar circRNA Microarray , qRT-PCR , UP , 72.50% , 96.00% , 0.915(p < 0.001) , Preclinical , ( ) .

Techniques: Expressing, Binding Assay

Comprehensive ceRNA Interaction Networks and Regulatory Axes in GBM. A circRNA/lncRNA–miRNA–mRNA interaction network, illustrating the competitive binding relationships between ncRNAs and mRNAs. The size and color of the nodes represent the strength of interaction and their centrality within the network, respectively. B Regulatory axis network of circRNAs, illustrating the routes of circRNA-mediated control, from circRNAs to miRNAs and on to their mRNA targets. C Regulatory axis network of lncRNAs, outlining specific pathways of regulation from lncRNAs, through miRNAs, to their mRNA targets (color figure online)

Journal: Clinical and Experimental Medicine

Article Title: Integrative analysis of glioblastoma multiforme: the power of non-coding RNAs and hub genes in cancer research

doi: 10.1007/s10238-025-01677-0

Figure Lengend Snippet: Comprehensive ceRNA Interaction Networks and Regulatory Axes in GBM. A circRNA/lncRNA–miRNA–mRNA interaction network, illustrating the competitive binding relationships between ncRNAs and mRNAs. The size and color of the nodes represent the strength of interaction and their centrality within the network, respectively. B Regulatory axis network of circRNAs, illustrating the routes of circRNA-mediated control, from circRNAs to miRNAs and on to their mRNA targets. C Regulatory axis network of lncRNAs, outlining specific pathways of regulation from lncRNAs, through miRNAs, to their mRNA targets (color figure online)

Article Snippet: GSE165926 , circRNA , GPL21825 , Arraystar Human CircRNA microarray , 12/4 , China , 2021.

Techniques: Binding Assay, Control