chrm3  (Alomone Labs)


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    Structured Review

    Alomone Labs chrm3
    Correlation between YAP/TAZ, MRTF/SRF, and muscarinic receptors in the human GI tract and urinary bladder . ( A ) For the table, RNA sequencing data from GTExPortal.org was used to correlate mRNA levels of YAP1 , TEAD3 , and WWTR1 vs MYOCD , MRTFA , SRF , CHRM2 , and <t>CHRM3</t> . Spearman Rho values for the indicated correlations are given for 5 sections of the GI tract and the urinary bladder. All Spearman Rho values in bold have a P value less than .0001. Examples of correlations in the transverse colon are highlighted in gray. ( B ) Examples of correlations in the transverse colon are plotted. White lines are best-fit linear regression lines. eso GEJ, esophagus gastroesophageal junction; colon s., colon sigmoid; colon t., colon transverse; ter. ileum, terminal ileum; TPM, transcripts per million.
    Chrm3, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/chrm3/product/Alomone Labs
    Average 94 stars, based on 4 article reviews
    Price from $9.99 to $1999.99
    chrm3 - by Bioz Stars, 2022-12
    94/100 stars

    Images

    1) Product Images from "Inducible Deletion of YAP and TAZ in Adult Mouse Smooth Muscle Causes Rapid and Lethal Colonic Pseudo-Obstruction"

    Article Title: Inducible Deletion of YAP and TAZ in Adult Mouse Smooth Muscle Causes Rapid and Lethal Colonic Pseudo-Obstruction

    Journal: Cellular and Molecular Gastroenterology and Hepatology

    doi: 10.1016/j.jcmgh.2020.09.014

    Correlation between YAP/TAZ, MRTF/SRF, and muscarinic receptors in the human GI tract and urinary bladder . ( A ) For the table, RNA sequencing data from GTExPortal.org was used to correlate mRNA levels of YAP1 , TEAD3 , and WWTR1 vs MYOCD , MRTFA , SRF , CHRM2 , and CHRM3 . Spearman Rho values for the indicated correlations are given for 5 sections of the GI tract and the urinary bladder. All Spearman Rho values in bold have a P value less than .0001. Examples of correlations in the transverse colon are highlighted in gray. ( B ) Examples of correlations in the transverse colon are plotted. White lines are best-fit linear regression lines. eso GEJ, esophagus gastroesophageal junction; colon s., colon sigmoid; colon t., colon transverse; ter. ileum, terminal ileum; TPM, transcripts per million.
    Figure Legend Snippet: Correlation between YAP/TAZ, MRTF/SRF, and muscarinic receptors in the human GI tract and urinary bladder . ( A ) For the table, RNA sequencing data from GTExPortal.org was used to correlate mRNA levels of YAP1 , TEAD3 , and WWTR1 vs MYOCD , MRTFA , SRF , CHRM2 , and CHRM3 . Spearman Rho values for the indicated correlations are given for 5 sections of the GI tract and the urinary bladder. All Spearman Rho values in bold have a P value less than .0001. Examples of correlations in the transverse colon are highlighted in gray. ( B ) Examples of correlations in the transverse colon are plotted. White lines are best-fit linear regression lines. eso GEJ, esophagus gastroesophageal junction; colon s., colon sigmoid; colon t., colon transverse; ter. ileum, terminal ileum; TPM, transcripts per million.

    Techniques Used: RNA Sequencing Assay

    2) Product Images from "Induction of detrusor underactivity by extensive vascular endothelial damages of iliac arteries in a rat model and its pathophysiology in the genetic levels"

    Article Title: Induction of detrusor underactivity by extensive vascular endothelial damages of iliac arteries in a rat model and its pathophysiology in the genetic levels

    Journal: Scientific Reports

    doi: 10.1038/s41598-019-52811-4

    Repression of P2rx1 by progressive vascular endothelial damage. ( a – c ) RQ-PCR ( a ) and western blot ( b , c ) analysis of the expressions of the cholinergic receptor muscarinic 2 ( Chrm2 ), cholinergic receptor muscarinic 3 ( Chrm3 ), and purinergic receptor P2X 1 ( P2rx1 ) genes in the bladders of rats in the indicated groups. Expression levels of the indicated transcripts are presented as % Gapdh . For western blot analysis, β-actin was used as a loading control, and the expression levels of the indicated proteins were normalized to the β-actin value. ( d , e ) Representative images ( d ) and quantification analysis ( e ) of the immunohistochemical staining for the P2rx1 protein (original magnification ×200, scale bar = 200 μm). All quantification results are presented as mean ± SEM. *p
    Figure Legend Snippet: Repression of P2rx1 by progressive vascular endothelial damage. ( a – c ) RQ-PCR ( a ) and western blot ( b , c ) analysis of the expressions of the cholinergic receptor muscarinic 2 ( Chrm2 ), cholinergic receptor muscarinic 3 ( Chrm3 ), and purinergic receptor P2X 1 ( P2rx1 ) genes in the bladders of rats in the indicated groups. Expression levels of the indicated transcripts are presented as % Gapdh . For western blot analysis, β-actin was used as a loading control, and the expression levels of the indicated proteins were normalized to the β-actin value. ( d , e ) Representative images ( d ) and quantification analysis ( e ) of the immunohistochemical staining for the P2rx1 protein (original magnification ×200, scale bar = 200 μm). All quantification results are presented as mean ± SEM. *p

    Techniques Used: Polymerase Chain Reaction, Western Blot, Expressing, Immunohistochemistry, Staining

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    Alomone Labs anti chrm3 antibody
    Anti Chrm3 Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti chrm3 antibody/product/Alomone Labs
    Average 94 stars, based on 7 article reviews
    Price from $9.99 to $1999.99
    anti chrm3 antibody - by Bioz Stars, 2022-12
    94/100 stars
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