cholic acid  (Millipore)

 
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    Name:
    Cholic acid
    Description:
    Cholic acid is a major primary bile acid produced in the liver which facilitates fat absorption and cholesterol excretion It is a non denaturing ionic detergent
    Catalog Number:
    c1129
    Price:
    None
    Applications:
    Non-denaturing ionic detergent used for extraction of membrane proteins.
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    Structured Review

    Millipore cholic acid
    Cholic acid
    Cholic acid is a major primary bile acid produced in the liver which facilitates fat absorption and cholesterol excretion It is a non denaturing ionic detergent
    https://www.bioz.com/result/cholic acid/product/Millipore
    Average 99 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    cholic acid - by Bioz Stars, 2021-03
    99/100 stars

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    other:

    Article Title: Bile acids inhibit human purinergic receptor P2X4 in a heterologous expression system
    Article Snippet: Chemicals Sodium salt of cholic (CA) and tauro-cholic acid (t-CA), deoxycholic (DCA) and tauro-deoxycholic acid (t-DCA), chenodeoxycholic (CDCA) and tauro-chenodeoxycholic acid (t-CDCA), as well as ATP dipotassium salt were purchased from Sigma-Aldrich.

    Article Title: Naringin Reverses High-Cholesterol Diet-Induced Vascular Dysfunction and Oxidative Stress in Rats via Regulating LOX-1 and NADPH Oxidase Subunit Expression
    Article Snippet: Drugs and Chemicals Naringin (purity > 90%), cholic acid, ACh, SNP, and PE were purchased from Sigma (St Louis, MO, USA).

    MTT Assay:

    Article Title: “OA02” Peptide Facilitates the Precise Targeting of Paclitaxel-Loaded Micellar Nanoparticles to Ovarian Cancer In Vivo
    Article Snippet: Taxol® (Mayne Pharma, Paramus, NJ) was obtained from the UC Davis Cancer Center Pharmacy. .. Cholic acid, MTT [3-(4, 5-dimethyldiazol-2-yl)-2, 5 diphenyl tetrazolium bromid] and fluorescein isothiocyanate (FITC) and all other chemicals were purchased from Sigma-Aldrich. .. Boc-NH-PEG5k -CA8 telodendrimer was first synthesized as described previously ( ).

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  • 94
    Millipore tauro cholic acid t ca
    <t>DCA</t> in <t>tauro-conjugated</t> or unconjugated form has the strongest inhibitory effect on P2X4 among the bile acids tested. (A–F) Left panels: Representative whole-cell current traces recorded in human P2X4 expressing oocytes. ATP (10 µM) and bile acids (A: t-DCA; B: DCA; C: t-CDCA; D: CDCA; E: t-CA; F: CA; all in a concentration of 250 µM) were present in the bath solution as indicated by open and filled bars, respectively. Zero current level is indicated by a dotted horizontal line. Right panels: Summary of results from similar experiments as shown in the corresponding left panels. The ATP-activated current integral was calculated in each recording as described in Fig. 1 and normalized to the mean current integral determined in matched control oocytes (i.e., in the absence of bile acids) from the corresponding batch of oocytes (normalized current integral). Mean ± SEM values and individual data points are shown (20 ≤ n ≤ 21; N = 2); *** , *, Significantly different, P
    Tauro Cholic Acid T Ca, supplied by Millipore, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tauro cholic acid t ca/product/Millipore
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    tauro cholic acid t ca - by Bioz Stars, 2021-03
    94/100 stars
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    97
    Millipore wt wt cholic acid containing diet
    FXR activation induces SHP by binding to the IR1s in both the promoter and the downstream enhancer region. A. Induction of SHP mRNA expression in liver after treatment with either <t>cholic</t> <t>acid</t> <t>(CA)-containing</t> <t>diet</t> or GW4064 in <t>WT</t> and FXR-KO mice, as described
    Wt Wt Cholic Acid Containing Diet, supplied by Millipore, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/wt wt cholic acid containing diet/product/Millipore
    Average 97 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    wt wt cholic acid containing diet - by Bioz Stars, 2021-03
    97/100 stars
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    DCA in tauro-conjugated or unconjugated form has the strongest inhibitory effect on P2X4 among the bile acids tested. (A–F) Left panels: Representative whole-cell current traces recorded in human P2X4 expressing oocytes. ATP (10 µM) and bile acids (A: t-DCA; B: DCA; C: t-CDCA; D: CDCA; E: t-CA; F: CA; all in a concentration of 250 µM) were present in the bath solution as indicated by open and filled bars, respectively. Zero current level is indicated by a dotted horizontal line. Right panels: Summary of results from similar experiments as shown in the corresponding left panels. The ATP-activated current integral was calculated in each recording as described in Fig. 1 and normalized to the mean current integral determined in matched control oocytes (i.e., in the absence of bile acids) from the corresponding batch of oocytes (normalized current integral). Mean ± SEM values and individual data points are shown (20 ≤ n ≤ 21; N = 2); *** , *, Significantly different, P

    Journal: The Journal of General Physiology

    Article Title: Bile acids inhibit human purinergic receptor P2X4 in a heterologous expression system

    doi: 10.1085/jgp.201812291

    Figure Lengend Snippet: DCA in tauro-conjugated or unconjugated form has the strongest inhibitory effect on P2X4 among the bile acids tested. (A–F) Left panels: Representative whole-cell current traces recorded in human P2X4 expressing oocytes. ATP (10 µM) and bile acids (A: t-DCA; B: DCA; C: t-CDCA; D: CDCA; E: t-CA; F: CA; all in a concentration of 250 µM) were present in the bath solution as indicated by open and filled bars, respectively. Zero current level is indicated by a dotted horizontal line. Right panels: Summary of results from similar experiments as shown in the corresponding left panels. The ATP-activated current integral was calculated in each recording as described in Fig. 1 and normalized to the mean current integral determined in matched control oocytes (i.e., in the absence of bile acids) from the corresponding batch of oocytes (normalized current integral). Mean ± SEM values and individual data points are shown (20 ≤ n ≤ 21; N = 2); *** , *, Significantly different, P

    Article Snippet: Chemicals Sodium salt of cholic (CA) and tauro-cholic acid (t-CA), deoxycholic (DCA) and tauro-deoxycholic acid (t-DCA), chenodeoxycholic (CDCA) and tauro-chenodeoxycholic acid (t-CDCA), as well as ATP dipotassium salt were purchased from Sigma-Aldrich.

    Techniques: Expressing, Concentration Assay

    Ran is a novel substrate of TIP60 in mitotic cells. ( A ) Real-time mitosis in Mog1-suppressed cells was scored as a function of TIP60 inhibition by NU9056. Scale bar, 10 μm. ( B and C ) Statistics of the chromosome segregation abnormality in the presence of TIP60 inhibitor (NU9056) or PCAF inhibitor (C146) ( B ) and in cells transfected with TIP60 siRNA ( C ) (mean ± SEM, n = 62, siControl; n = 36, siMog1; n = 55, DMSO; n = 39, C146; n = 38, NU9056; n = 28, siMog1 + DMSO; n = 26, siMog1 + C146; n = 35, siMog1 + NU9056; n = 33, siTIP60; n = 35, siMog1 + siTIP60). Statistical significance was tested by two-sided t -test; ** P

    Journal: Journal of Molecular Cell Biology

    Article Title: Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation

    doi: 10.1093/jmcb/mjx045

    Figure Lengend Snippet: Ran is a novel substrate of TIP60 in mitotic cells. ( A ) Real-time mitosis in Mog1-suppressed cells was scored as a function of TIP60 inhibition by NU9056. Scale bar, 10 μm. ( B and C ) Statistics of the chromosome segregation abnormality in the presence of TIP60 inhibitor (NU9056) or PCAF inhibitor (C146) ( B ) and in cells transfected with TIP60 siRNA ( C ) (mean ± SEM, n = 62, siControl; n = 36, siMog1; n = 55, DMSO; n = 39, C146; n = 38, NU9056; n = 28, siMog1 + DMSO; n = 26, siMog1 + C146; n = 35, siMog1 + NU9056; n = 33, siTIP60; n = 35, siMog1 + siTIP60). Statistical significance was tested by two-sided t -test; ** P

    Article Snippet: C146 was from Sigma and used at 1 μM.

    Techniques: Inhibition, Transfection

    FXR activation induces SHP by binding to the IR1s in both the promoter and the downstream enhancer region. A. Induction of SHP mRNA expression in liver after treatment with either cholic acid (CA)-containing diet or GW4064 in WT and FXR-KO mice, as described

    Journal: Molecular Endocrinology

    Article Title: Farnesoid X Receptor Activation Mediates Head-to-Tail Chromatin Looping in the Nr0b2 Gene Encoding Small Heterodimer Partner

    doi: 10.1210/me.2010-0014

    Figure Lengend Snippet: FXR activation induces SHP by binding to the IR1s in both the promoter and the downstream enhancer region. A. Induction of SHP mRNA expression in liver after treatment with either cholic acid (CA)-containing diet or GW4064 in WT and FXR-KO mice, as described

    Article Snippet: The 1% (wt/wt) cholic acid-containing diet was made in house by mixing cholic acid (Sigma Chemical Co., St. Louis, MO) with regular rodent chow diet, which was completely dried.

    Techniques: Activation Assay, Binding Assay, Expressing, Mouse Assay