Chimeric Mouse Human Anti Cd20 Antibody Rituximab C2b8, supplied by Biogen Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/chimeric mouse human anti cd20 antibody rituximab c2b8/product/Biogen Inc
Average 86 stars, based on 1 article reviews
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1) Product Images from "Recombinant anti-CD20 antibody fragments for microPET imaging of B-cell lymphoma"
Article Title: Recombinant anti-CD20 antibody fragments for microPET imaging of B-cell lymphoma
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Figure Legend Snippet: Characterization of purified rituximab minibody and scFv-Fc DM. A) Schematic presentations of the minibody and scFv-Fc DM. Both proteins assemble into covalent bound homodimers through cysteines in the hinge region. The two mutations (H310A and H435Q) present in the Fc region are indicated. V L = variable light. V H = variable heavy. C H = constant heavy. B) Coomassie stained SDS-PAGE of purified proteins under non-reducing (lanes 2) and reducing (lanes 3) conditions. Lane 1 = molecular marker. C) Size-exclusion chromatography analysis of purified minibody and scFv-Fc DM. D) Flow cytometric analysis of CD20 binding by rituximab antibody fragments. Purified proteins were assayed for binding to 38C13-huCD20 cells. Bound protein was detected with phycoerythrin (PE) conjugated goat anti-human (Fc specific) antibodies. Rituximab was used as positive control and secondary antibody alone as negative control.
Techniques Used: Purification, Staining, SDS Page, Marker, Size-exclusion Chromatography, Flow Cytometry, Binding Assay, Positive Control, Negative Control
Article Title: Phase I study of chimeric anti-CD20 monoclonal antibody in Chinese patients with CD20-positive non-Hodgkin's lymphoma
Article Snippet: In
Article Title: ImmunoPET imaging of B-cell lymphoma using 124I-anti-CD20 scFv dimers (diabodies)
Article Snippet: .. A total of five different