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chimeric immunoglobulin g1 monoclonal antibody  (Astellas)

 
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    Astellas chimeric immunoglobulin g1 monoclonal antibody
    Chimeric Immunoglobulin G1 Monoclonal Antibody, supplied by Astellas, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/chimeric immunoglobulin g1 monoclonal antibody/product/Astellas
    Average 86 stars, based on 1 article reviews
    chimeric immunoglobulin g1 monoclonal antibody - by Bioz Stars, 2025-03
    86/100 stars

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    CD19 positive B-cell and CD20 positive B-cell counts at measured time points

    Journal: Chinese Journal of Cancer Research

    Article Title: A multi-center, open-label, randomized, parallel-controlled phase II study comparing pharmacokinetic, pharmacodynamics and safety of ripertamab (SCT400) to rituximab (MabThera ® ) in patients with CD20-positive B-cell non-Hodgkin lymphoma

    doi: 10.21147/j.issn.1000-9604.2022.06.08

    Figure Lengend Snippet: CD19 positive B-cell and CD20 positive B-cell counts at measured time points

    Article Snippet: Ripertamab (SCT400), a recombinant human-mouse chimeric anti-CD20 immunoglobulin G1 (IgG1) monoclonal antibody developed by Sinocelltech Ltd, Beijing, China, has the same amino acid sequence of antigen binding sites and variable region to rituximab, except one amino acid difference in position 219 of heavy chain constant region 1 (valine in ripertamab and alanine in rituximab).

    Techniques:

    Changes of peripheral blood CD20-positive B-cell absolute counts. Rituximab refers to MabThera®. pcs, pieces.

    Journal: Chinese Journal of Cancer Research

    Article Title: A multi-center, open-label, randomized, parallel-controlled phase II study comparing pharmacokinetic, pharmacodynamics and safety of ripertamab (SCT400) to rituximab (MabThera ® ) in patients with CD20-positive B-cell non-Hodgkin lymphoma

    doi: 10.21147/j.issn.1000-9604.2022.06.08

    Figure Lengend Snippet: Changes of peripheral blood CD20-positive B-cell absolute counts. Rituximab refers to MabThera®. pcs, pieces.

    Article Snippet: Ripertamab (SCT400), a recombinant human-mouse chimeric anti-CD20 immunoglobulin G1 (IgG1) monoclonal antibody developed by Sinocelltech Ltd, Beijing, China, has the same amino acid sequence of antigen binding sites and variable region to rituximab, except one amino acid difference in position 219 of heavy chain constant region 1 (valine in ripertamab and alanine in rituximab).

    Techniques: