Journal: International Journal of Molecular Sciences

Article Title: The Role of P2X7 Purinergic Receptors in the Renal Inflammation Associated with Angiotensin II-Induced Hypertension

doi: 10.3390/ijms21114041

Figure Lengend Snippet: Infiltrating T cells (CD3, CD5), B cells (CD 20) and macrophages [CD68], are increased in the renal cortical interstitium of the angiotensin-infused rats (Ang II group n = 7), and reduced by the administration of BBG (Ang II + BBG n = 7). CD45 antigen is a leukocyte common antigen predominantly expressed in lymphocytes. White bars (□) Sham; Black bars (■) AngII; and grey bars ( ■ ) Ang II + BBG. * p < 0.001 vs. sham, ** p < 0.05 vs. Ang II. Ang II = angiotensin II; BBG = brilliant blue G.

Article Snippet: Tissues were co-stained with phycoerythrin (PE)-labeled antibodies, anti-CD3-PE, -CD5-PE, -CD20-PE, -CD45-PE, or -CD68-PE antibodies (Cat #: sc-20047 PE, sc-1180 PE, sc-393894 PE, sc-1178 PE, sc-20060 PE, mouse monoclonal antibodies Santa Cruz Biotechnology, Dallas TX, USA), for localization of receptors expressed in inflammatory cells.

Techniques:

Journal: International Journal of Molecular Sciences

Article Title: The Role of P2X7 Purinergic Receptors in the Renal Inflammation Associated with Angiotensin II-Induced Hypertension

doi: 10.3390/ijms21114041

Figure Lengend Snippet: P2X7 receptors (second column) in the infiltrating T cells of Ang II group co-localize with cluster differentiation (CD, first column) antigens in T cells (CD 3 positive cells), B cells (CD5 and CD20 positive cells), macrophages (CD68 positive cells) and leukocyte common antigen CD45, predominantly expressed in T lymphocytes.

Article Snippet: Tissues were co-stained with phycoerythrin (PE)-labeled antibodies, anti-CD3-PE, -CD5-PE, -CD20-PE, -CD45-PE, or -CD68-PE antibodies (Cat #: sc-20047 PE, sc-1180 PE, sc-393894 PE, sc-1178 PE, sc-20060 PE, mouse monoclonal antibodies Santa Cruz Biotechnology, Dallas TX, USA), for localization of receptors expressed in inflammatory cells.

Techniques: