cd166  (Sino Biological)


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    Structured Review

    Sino Biological cd166
    Cd166, supplied by Sino Biological, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cd166/product/Sino Biological
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    cd166 - by Bioz Stars, 2022-10
    86/100 stars

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  • 92
    Sino Biological his tagged cd166 ecd
    Probody therapeutic preferentially accumulate in the tumor due to target binding. ( A ) Detection of CX-2009 and CX-191 in tumors of H292 xenograft-bearing mice dosed with either [ 89 Zr]Zr-CX-2009 or [ 89 Zr]Zr-CX-191 at 10, 110, or 510 µg (radiolabeled + cold antibody) and collected at 72 h p.i. ( B ) Similar pattern of CX-2009 and CX-191 intra-tumoral distribution with <t>CD166</t> expression staining in serial sections of H292 xenografts collected 72 h after dosing of mice with 510 µg CX-2009 or CX-191. ( C ) Immunofluorescence staining of CX-2009, CX-191, CX-1031, and CX-090 in tumor, liver, and kidney of H292 xenograft mice collected 72 h after administration of 510 µg of the respective conjugates. hIgG: staining with anti-human IgG; DAPI: nuclear counter staining with DAPI; CD166: staining for CD166 expression.
    His Tagged Cd166 Ecd, supplied by Sino Biological, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/his tagged cd166 ecd/product/Sino Biological
    Average 92 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    his tagged cd166 ecd - by Bioz Stars, 2022-10
    92/100 stars
      Buy from Supplier

    86
    Sino Biological cd166
    Probody therapeutic preferentially accumulate in the tumor due to target binding. ( A ) Detection of CX-2009 and CX-191 in tumors of H292 xenograft-bearing mice dosed with either [ 89 Zr]Zr-CX-2009 or [ 89 Zr]Zr-CX-191 at 10, 110, or 510 µg (radiolabeled + cold antibody) and collected at 72 h p.i. ( B ) Similar pattern of CX-2009 and CX-191 intra-tumoral distribution with <t>CD166</t> expression staining in serial sections of H292 xenografts collected 72 h after dosing of mice with 510 µg CX-2009 or CX-191. ( C ) Immunofluorescence staining of CX-2009, CX-191, CX-1031, and CX-090 in tumor, liver, and kidney of H292 xenograft mice collected 72 h after administration of 510 µg of the respective conjugates. hIgG: staining with anti-human IgG; DAPI: nuclear counter staining with DAPI; CD166: staining for CD166 expression.
    Cd166, supplied by Sino Biological, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cd166/product/Sino Biological
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    cd166 - by Bioz Stars, 2022-10
    86/100 stars
      Buy from Supplier

    88
    Sino Biological cd166 his
    Probody therapeutic preferentially accumulate in the tumor due to target binding. ( A ) Detection of CX-2009 and CX-191 in tumors of H292 xenograft-bearing mice dosed with either [ 89 Zr]Zr-CX-2009 or [ 89 Zr]Zr-CX-191 at 10, 110, or 510 µg (radiolabeled + cold antibody) and collected at 72 h p.i. ( B ) Similar pattern of CX-2009 and CX-191 intra-tumoral distribution with <t>CD166</t> expression staining in serial sections of H292 xenografts collected 72 h after dosing of mice with 510 µg CX-2009 or CX-191. ( C ) Immunofluorescence staining of CX-2009, CX-191, CX-1031, and CX-090 in tumor, liver, and kidney of H292 xenograft mice collected 72 h after administration of 510 µg of the respective conjugates. hIgG: staining with anti-human IgG; DAPI: nuclear counter staining with DAPI; CD166: staining for CD166 expression.
    Cd166 His, supplied by Sino Biological, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cd166 his/product/Sino Biological
    Average 88 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    cd166 his - by Bioz Stars, 2022-10
    88/100 stars
      Buy from Supplier

    90
    Sino Biological differentiation 166
    Probody therapeutic preferentially accumulate in the tumor due to target binding. ( A ) Detection of CX-2009 and CX-191 in tumors of H292 xenograft-bearing mice dosed with either [ 89 Zr]Zr-CX-2009 or [ 89 Zr]Zr-CX-191 at 10, 110, or 510 µg (radiolabeled + cold antibody) and collected at 72 h p.i. ( B ) Similar pattern of CX-2009 and CX-191 intra-tumoral distribution with <t>CD166</t> expression staining in serial sections of H292 xenografts collected 72 h after dosing of mice with 510 µg CX-2009 or CX-191. ( C ) Immunofluorescence staining of CX-2009, CX-191, CX-1031, and CX-090 in tumor, liver, and kidney of H292 xenograft mice collected 72 h after administration of 510 µg of the respective conjugates. hIgG: staining with anti-human IgG; DAPI: nuclear counter staining with DAPI; CD166: staining for CD166 expression.
    Differentiation 166, supplied by Sino Biological, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/differentiation 166/product/Sino Biological
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    differentiation 166 - by Bioz Stars, 2022-10
    90/100 stars
      Buy from Supplier

    Image Search Results


    Probody therapeutic preferentially accumulate in the tumor due to target binding. ( A ) Detection of CX-2009 and CX-191 in tumors of H292 xenograft-bearing mice dosed with either [ 89 Zr]Zr-CX-2009 or [ 89 Zr]Zr-CX-191 at 10, 110, or 510 µg (radiolabeled + cold antibody) and collected at 72 h p.i. ( B ) Similar pattern of CX-2009 and CX-191 intra-tumoral distribution with CD166 expression staining in serial sections of H292 xenografts collected 72 h after dosing of mice with 510 µg CX-2009 or CX-191. ( C ) Immunofluorescence staining of CX-2009, CX-191, CX-1031, and CX-090 in tumor, liver, and kidney of H292 xenograft mice collected 72 h after administration of 510 µg of the respective conjugates. hIgG: staining with anti-human IgG; DAPI: nuclear counter staining with DAPI; CD166: staining for CD166 expression.

    Journal: Theranostics

    Article Title: The tumor targeting performance of anti-CD166 Probody drug conjugate CX-2009 and its parental derivatives as monitored by 89Zr-immuno-PET in xenograft bearing mice

    doi: 10.7150/thno.44334

    Figure Lengend Snippet: Probody therapeutic preferentially accumulate in the tumor due to target binding. ( A ) Detection of CX-2009 and CX-191 in tumors of H292 xenograft-bearing mice dosed with either [ 89 Zr]Zr-CX-2009 or [ 89 Zr]Zr-CX-191 at 10, 110, or 510 µg (radiolabeled + cold antibody) and collected at 72 h p.i. ( B ) Similar pattern of CX-2009 and CX-191 intra-tumoral distribution with CD166 expression staining in serial sections of H292 xenografts collected 72 h after dosing of mice with 510 µg CX-2009 or CX-191. ( C ) Immunofluorescence staining of CX-2009, CX-191, CX-1031, and CX-090 in tumor, liver, and kidney of H292 xenograft mice collected 72 h after administration of 510 µg of the respective conjugates. hIgG: staining with anti-human IgG; DAPI: nuclear counter staining with DAPI; CD166: staining for CD166 expression.

    Article Snippet: Sumo-tagged human CD166 extracellular domain (ECD) protein was produced at CytomX Therapeutics, Inc. (South San Francisco, California, USA), and His-tagged CD166 ECD from mouse (cat# 5005-M008) was purchased from Sino Biological US Inc. (Wayne, Pennsylvania, USA).

    Techniques: Binding Assay, Mouse Assay, Expressing, Staining, Immunofluorescence

    Binding of CX-2009, CX-191, CX-1031, and CX-090 to recombinant CD166 protein from (A) human and (B) mouse origin. Data points represent the mean of duplicate wells. Error bars show standard error of the mean (SEM). Apparent K d (equilibrium dissociation constant) are listed as measured under defined conditions.

    Journal: Theranostics

    Article Title: The tumor targeting performance of anti-CD166 Probody drug conjugate CX-2009 and its parental derivatives as monitored by 89Zr-immuno-PET in xenograft bearing mice

    doi: 10.7150/thno.44334

    Figure Lengend Snippet: Binding of CX-2009, CX-191, CX-1031, and CX-090 to recombinant CD166 protein from (A) human and (B) mouse origin. Data points represent the mean of duplicate wells. Error bars show standard error of the mean (SEM). Apparent K d (equilibrium dissociation constant) are listed as measured under defined conditions.

    Article Snippet: Sumo-tagged human CD166 extracellular domain (ECD) protein was produced at CytomX Therapeutics, Inc. (South San Francisco, California, USA), and His-tagged CD166 ECD from mouse (cat# 5005-M008) was purchased from Sino Biological US Inc. (Wayne, Pennsylvania, USA).

    Techniques: Binding Assay, Recombinant