rabbit anti cacna1b  (Alomone Labs)


Bioz Verified Symbol Alomone Labs is a verified supplier
Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Alomone Labs rabbit anti cacna1b
    Primary antibodies used in the present study.
    Rabbit Anti Cacna1b, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti cacna1b/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti cacna1b - by Bioz Stars, 2023-01
    94/100 stars

    Images

    1) Product Images from "Silencing the ACAT1 Gene in Human SH-SY5Y Neuroblastoma Cells Inhibits the Expression of Cyclo-Oxygenase 2 (COX2) and Reduces β-Amyloid-Induced Toxicity Due to Activation of Protein Kinase C (PKC) and ERK"

    Article Title: Silencing the ACAT1 Gene in Human SH-SY5Y Neuroblastoma Cells Inhibits the Expression of Cyclo-Oxygenase 2 (COX2) and Reduces β-Amyloid-Induced Toxicity Due to Activation of Protein Kinase C (PKC) and ERK

    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    doi: 10.12659/MSM.912862

    Primary antibodies used in the present study.
    Figure Legend Snippet: Primary antibodies used in the present study.

    Techniques Used:

    Effects of knockdown ACAT1 on CACNAs, PKC, and ERK phosphorylation and in Aβ-induced SH-SY5Y cells. ( A ) Western blot results showed that the relative expression of CACNA1b and CACNA2d1 was increased significantly, while the total PKC and the ratio of phospho-ERK (p-ERK)/ERK were decreased significantly after Aβ 25-35 treatment. ( B ) Knockdown of ACAT1 rescued the reduction of PKC and phosphorylation level of ERK, and also retarded the upregulation of CACNA1b and CACNA2d1 induced by Aβ. (** P <0.01 and * P <0.05).
    Figure Legend Snippet: Effects of knockdown ACAT1 on CACNAs, PKC, and ERK phosphorylation and in Aβ-induced SH-SY5Y cells. ( A ) Western blot results showed that the relative expression of CACNA1b and CACNA2d1 was increased significantly, while the total PKC and the ratio of phospho-ERK (p-ERK)/ERK were decreased significantly after Aβ 25-35 treatment. ( B ) Knockdown of ACAT1 rescued the reduction of PKC and phosphorylation level of ERK, and also retarded the upregulation of CACNA1b and CACNA2d1 induced by Aβ. (** P <0.01 and * P <0.05).

    Techniques Used: Western Blot, Expressing

    rabbit anti cacna1b  (Alomone Labs)


    Bioz Verified Symbol Alomone Labs is a verified supplier
    Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Alomone Labs rabbit anti cacna1b
    Primary antibodies used in the present study.
    Rabbit Anti Cacna1b, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti cacna1b/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti cacna1b - by Bioz Stars, 2023-01
    94/100 stars

    Images

    1) Product Images from "Silencing the ACAT1 Gene in Human SH-SY5Y Neuroblastoma Cells Inhibits the Expression of Cyclo-Oxygenase 2 (COX2) and Reduces β-Amyloid-Induced Toxicity Due to Activation of Protein Kinase C (PKC) and ERK"

    Article Title: Silencing the ACAT1 Gene in Human SH-SY5Y Neuroblastoma Cells Inhibits the Expression of Cyclo-Oxygenase 2 (COX2) and Reduces β-Amyloid-Induced Toxicity Due to Activation of Protein Kinase C (PKC) and ERK

    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    doi: 10.12659/MSM.912862

    Primary antibodies used in the present study.
    Figure Legend Snippet: Primary antibodies used in the present study.

    Techniques Used:

    Effects of knockdown ACAT1 on CACNAs, PKC, and ERK phosphorylation and in Aβ-induced SH-SY5Y cells. ( A ) Western blot results showed that the relative expression of CACNA1b and CACNA2d1 was increased significantly, while the total PKC and the ratio of phospho-ERK (p-ERK)/ERK were decreased significantly after Aβ 25-35 treatment. ( B ) Knockdown of ACAT1 rescued the reduction of PKC and phosphorylation level of ERK, and also retarded the upregulation of CACNA1b and CACNA2d1 induced by Aβ. (** P <0.01 and * P <0.05).
    Figure Legend Snippet: Effects of knockdown ACAT1 on CACNAs, PKC, and ERK phosphorylation and in Aβ-induced SH-SY5Y cells. ( A ) Western blot results showed that the relative expression of CACNA1b and CACNA2d1 was increased significantly, while the total PKC and the ratio of phospho-ERK (p-ERK)/ERK were decreased significantly after Aβ 25-35 treatment. ( B ) Knockdown of ACAT1 rescued the reduction of PKC and phosphorylation level of ERK, and also retarded the upregulation of CACNA1b and CACNA2d1 induced by Aβ. (** P <0.01 and * P <0.05).

    Techniques Used: Western Blot, Expressing

    cav2 2  (Alomone Labs)


    Bioz Verified Symbol Alomone Labs is a verified supplier
    Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Alomone Labs cav2 2
    Primer sequences.
    Cav2 2, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cav2 2/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    cav2 2 - by Bioz Stars, 2023-01
    94/100 stars

    Images

    1) Product Images from "Upregulation of N-Type Voltage-Gated Calcium Channels Induces Neuropathic Pain in Experimental Autoimmune Neuritis"

    Article Title: Upregulation of N-Type Voltage-Gated Calcium Channels Induces Neuropathic Pain in Experimental Autoimmune Neuritis

    Journal: Evidence-based Complementary and Alternative Medicine : eCAM

    doi: 10.1155/2022/8547095

    Primer sequences.
    Figure Legend Snippet: Primer sequences.

    Techniques Used: Sequencing

    Effect of Cav2.2 on clinical score and sciatic nerve tissue of rats. (a) Clinical score record of rats during 18 days of immunization; (b) changes in body weight of rats during 18 days of immunization; (c) luxol fast blue (LFB) staining-based observation of the degree of cell infiltration and demyelination in sciatic nerve tissue of rats on the 18 th day of immunization. ∗∗ P < 0.01 vs. control group, ## P < 0.01 vs. EAN-shRNA group.
    Figure Legend Snippet: Effect of Cav2.2 on clinical score and sciatic nerve tissue of rats. (a) Clinical score record of rats during 18 days of immunization; (b) changes in body weight of rats during 18 days of immunization; (c) luxol fast blue (LFB) staining-based observation of the degree of cell infiltration and demyelination in sciatic nerve tissue of rats on the 18 th day of immunization. ∗∗ P < 0.01 vs. control group, ## P < 0.01 vs. EAN-shRNA group.

    Techniques Used: Staining, shRNA

    Effect of Cav2.2 on allodynia in rats. (a–d) Measurement of withdrawal threshold to mechanical (a), thermal (b), and cold (c) stimulation, and mechanical hyperalgesia threshold (d) during 18 days of immunization. ∗∗ P < 0.01 vs. Control group, ## P < 0.01 vs. EAN-shRNA group.
    Figure Legend Snippet: Effect of Cav2.2 on allodynia in rats. (a–d) Measurement of withdrawal threshold to mechanical (a), thermal (b), and cold (c) stimulation, and mechanical hyperalgesia threshold (d) during 18 days of immunization. ∗∗ P < 0.01 vs. Control group, ## P < 0.01 vs. EAN-shRNA group.

    Techniques Used: shRNA

    Effect of Cav2.2 on rat inflammatory response. (a) ELISA-based measurement of IL-6 and TNF- α expression in rat serum; (b) qRT-PCR-based measurement of mRNA expression of iNOS, MCP-1, and Cav2.2 in rat sciatic nerve; (c) western blot-based measurement of protein expression of iNOS, MCP-1, and Cav2.2 in rat sciatic nerve. ∗ P < 0.05 and ∗∗ P < 0.01 vs. control group, # P < 0.05 and ## P < 0.01 vs. EAN-shRNA group.
    Figure Legend Snippet: Effect of Cav2.2 on rat inflammatory response. (a) ELISA-based measurement of IL-6 and TNF- α expression in rat serum; (b) qRT-PCR-based measurement of mRNA expression of iNOS, MCP-1, and Cav2.2 in rat sciatic nerve; (c) western blot-based measurement of protein expression of iNOS, MCP-1, and Cav2.2 in rat sciatic nerve. ∗ P < 0.05 and ∗∗ P < 0.01 vs. control group, # P < 0.05 and ## P < 0.01 vs. EAN-shRNA group.

    Techniques Used: Enzyme-linked Immunosorbent Assay, Expressing, Quantitative RT-PCR, Western Blot, shRNA

    α1b  (Alomone Labs)


    Bioz Verified Symbol Alomone Labs is a verified supplier
    Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Alomone Labs α1b
    Ca channel α 1 subunits co-express with the ganglion cell antibody RBPMS in vertical sections showing the inner plexiform layer (IPL), the ganglion cell layer (GCL) and the nerve fiber layer (NFL). ( Top row ) Double immunostaining with α1C subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). RGC axons (arrowhead) as well as putative Müller and neuronal cell processes in the IPL showed immunostaining. Control preadsorption of α1C antibody with the immunization peptide showed no staining. ( Second row ) Double immunostaining with α1D subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Numerous processes in the IPL as well as the RGC axons throughout the NFL (arrowhead) were also labelled. Control preadsorption of α1D antibody with the immunization peptide showed no staining. ( Third row ) Double immunostaining with <t>α1B</t> subunit and RBPMS antibodies shows colocalization in RGC somata (filled arrow). Processes in the IPL, putative displaced amacrine cells in the GCL (open arrows) and RGC axons throughout the NFL (arrowheads) showed immunostaining. Control preadsorption of α1B antibody with the immunization peptide showed no staining. ( Bottom row ) Double immunostaining with α1A subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Labelling in the IPL and in putative displaced amacrine cells in the GCL (open arrows) was also seen. Control preadsorption of α1A antibody with the immunization peptide showed no staining. Scale bar is 20 µm.
    α1b, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/α1b/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    α1b - by Bioz Stars, 2023-01
    94/100 stars

    Images

    1) Product Images from "Differential Calcium Signaling Mediated by Voltage-Gated Calcium Channels in Rat Retinal Ganglion Cells and Their Unmyelinated Axons"

    Article Title: Differential Calcium Signaling Mediated by Voltage-Gated Calcium Channels in Rat Retinal Ganglion Cells and Their Unmyelinated Axons

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0084507

    Ca channel α 1 subunits co-express with the ganglion cell antibody RBPMS in vertical sections showing the inner plexiform layer (IPL), the ganglion cell layer (GCL) and the nerve fiber layer (NFL). ( Top row ) Double immunostaining with α1C subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). RGC axons (arrowhead) as well as putative Müller and neuronal cell processes in the IPL showed immunostaining. Control preadsorption of α1C antibody with the immunization peptide showed no staining. ( Second row ) Double immunostaining with α1D subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Numerous processes in the IPL as well as the RGC axons throughout the NFL (arrowhead) were also labelled. Control preadsorption of α1D antibody with the immunization peptide showed no staining. ( Third row ) Double immunostaining with α1B subunit and RBPMS antibodies shows colocalization in RGC somata (filled arrow). Processes in the IPL, putative displaced amacrine cells in the GCL (open arrows) and RGC axons throughout the NFL (arrowheads) showed immunostaining. Control preadsorption of α1B antibody with the immunization peptide showed no staining. ( Bottom row ) Double immunostaining with α1A subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Labelling in the IPL and in putative displaced amacrine cells in the GCL (open arrows) was also seen. Control preadsorption of α1A antibody with the immunization peptide showed no staining. Scale bar is 20 µm.
    Figure Legend Snippet: Ca channel α 1 subunits co-express with the ganglion cell antibody RBPMS in vertical sections showing the inner plexiform layer (IPL), the ganglion cell layer (GCL) and the nerve fiber layer (NFL). ( Top row ) Double immunostaining with α1C subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). RGC axons (arrowhead) as well as putative Müller and neuronal cell processes in the IPL showed immunostaining. Control preadsorption of α1C antibody with the immunization peptide showed no staining. ( Second row ) Double immunostaining with α1D subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Numerous processes in the IPL as well as the RGC axons throughout the NFL (arrowhead) were also labelled. Control preadsorption of α1D antibody with the immunization peptide showed no staining. ( Third row ) Double immunostaining with α1B subunit and RBPMS antibodies shows colocalization in RGC somata (filled arrow). Processes in the IPL, putative displaced amacrine cells in the GCL (open arrows) and RGC axons throughout the NFL (arrowheads) showed immunostaining. Control preadsorption of α1B antibody with the immunization peptide showed no staining. ( Bottom row ) Double immunostaining with α1A subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Labelling in the IPL and in putative displaced amacrine cells in the GCL (open arrows) was also seen. Control preadsorption of α1A antibody with the immunization peptide showed no staining. Scale bar is 20 µm.

    Techniques Used: Double Immunostaining, Immunostaining, Staining

    R at wholemount retina labelled with RBPMS (red), α1B VGCC subunit (green), and NF-M (white) antibodies. α1B colocalized with RBPMS in RGC somata (filled arrow), NF-M in RGC axons (arrowhead) and putative displaced amacrine cells (open arrow). Stack of six optical sections each of 0.3 µm thickness. Scale bar is 20 µm.
    Figure Legend Snippet: R at wholemount retina labelled with RBPMS (red), α1B VGCC subunit (green), and NF-M (white) antibodies. α1B colocalized with RBPMS in RGC somata (filled arrow), NF-M in RGC axons (arrowhead) and putative displaced amacrine cells (open arrow). Stack of six optical sections each of 0.3 µm thickness. Scale bar is 20 µm.

    Techniques Used:

    anti ca v 2 2 cacna1b antibody voltage dependent n type calcium channel subunit α 1b  (Alomone Labs)


    Bioz Verified Symbol Alomone Labs is a verified supplier
    Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Alomone Labs anti ca v 2 2 cacna1b antibody voltage dependent n type calcium channel subunit α 1b
    Anti Ca V 2 2 Cacna1b Antibody Voltage Dependent N Type Calcium Channel Subunit α 1b, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti ca v 2 2 cacna1b antibody voltage dependent n type calcium channel subunit α 1b/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti ca v 2 2 cacna1b antibody voltage dependent n type calcium channel subunit α 1b - by Bioz Stars, 2023-01
    94/100 stars

    Images

    rabbit anti n type calcium channel  (Alomone Labs)


    Bioz Verified Symbol Alomone Labs is a verified supplier
    Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Alomone Labs rabbit anti n type calcium channel
    Rabbit Anti N Type Calcium Channel, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti n type calcium channel/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti n type calcium channel - by Bioz Stars, 2023-01
    94/100 stars

    Images

    anti cacna1b cav2 2 antibody  (Alomone Labs)


    Bioz Verified Symbol Alomone Labs is a verified supplier
    Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Alomone Labs anti cacna1b cav2 2 antibody
    Anti Cacna1b Cav2 2 Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti cacna1b cav2 2 antibody/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti cacna1b cav2 2 antibody - by Bioz Stars, 2023-01
    94/100 stars

    Images

    anti ca v 2 2 cacna1b antibody voltage dependent n type calcium channel subunit α 1b  (Alomone Labs)


    Bioz Verified Symbol Alomone Labs is a verified supplier
    Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Alomone Labs anti ca v 2 2 cacna1b antibody voltage dependent n type calcium channel subunit α 1b
    Anti Ca V 2 2 Cacna1b Antibody Voltage Dependent N Type Calcium Channel Subunit α 1b, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti ca v 2 2 cacna1b antibody voltage dependent n type calcium channel subunit α 1b/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti ca v 2 2 cacna1b antibody voltage dependent n type calcium channel subunit α 1b - by Bioz Stars, 2023-01
    94/100 stars

    Images

    rabbit anti cacna1b  (Alomone Labs)


    Bioz Verified Symbol Alomone Labs is a verified supplier
    Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Alomone Labs rabbit anti cacna1b
    Rabbit Anti Cacna1b, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti cacna1b/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti cacna1b - by Bioz Stars, 2023-01
    94/100 stars

    Images

    cav2 2  (Alomone Labs)


    Bioz Verified Symbol Alomone Labs is a verified supplier
    Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 92

    Structured Review

    Alomone Labs cav2 2
    Cav2 2, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cav2 2/product/Alomone Labs
    Average 92 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    cav2 2 - by Bioz Stars, 2023-01
    92/100 stars

    Images

    rabbit anti ca v 2 2 antibody  (Alomone Labs)


    Bioz Verified Symbol Alomone Labs is a verified supplier
    Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Alomone Labs rabbit anti ca v 2 2 antibody
    Rabbit Anti Ca V 2 2 Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti ca v 2 2 antibody/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti ca v 2 2 antibody - by Bioz Stars, 2023-01
    94/100 stars

    Images

    Similar Products

  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94
    Alomone Labs rabbit anti cacna1b
    Primary antibodies used in the present study.
    Rabbit Anti Cacna1b, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti cacna1b/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti cacna1b - by Bioz Stars, 2023-01
    94/100 stars
      Buy from Supplier

    94
    Alomone Labs cav2 2
    Primer sequences.
    Cav2 2, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cav2 2/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    cav2 2 - by Bioz Stars, 2023-01
    94/100 stars
      Buy from Supplier

    94
    Alomone Labs α1b
    Ca channel α 1 subunits co-express with the ganglion cell antibody RBPMS in vertical sections showing the inner plexiform layer (IPL), the ganglion cell layer (GCL) and the nerve fiber layer (NFL). ( Top row ) Double immunostaining with α1C subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). RGC axons (arrowhead) as well as putative Müller and neuronal cell processes in the IPL showed immunostaining. Control preadsorption of α1C antibody with the immunization peptide showed no staining. ( Second row ) Double immunostaining with α1D subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Numerous processes in the IPL as well as the RGC axons throughout the NFL (arrowhead) were also labelled. Control preadsorption of α1D antibody with the immunization peptide showed no staining. ( Third row ) Double immunostaining with <t>α1B</t> subunit and RBPMS antibodies shows colocalization in RGC somata (filled arrow). Processes in the IPL, putative displaced amacrine cells in the GCL (open arrows) and RGC axons throughout the NFL (arrowheads) showed immunostaining. Control preadsorption of α1B antibody with the immunization peptide showed no staining. ( Bottom row ) Double immunostaining with α1A subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Labelling in the IPL and in putative displaced amacrine cells in the GCL (open arrows) was also seen. Control preadsorption of α1A antibody with the immunization peptide showed no staining. Scale bar is 20 µm.
    α1b, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/α1b/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    α1b - by Bioz Stars, 2023-01
    94/100 stars
      Buy from Supplier

    94
    Alomone Labs anti ca v 2 2 cacna1b antibody voltage dependent n type calcium channel subunit α 1b
    Ca channel α 1 subunits co-express with the ganglion cell antibody RBPMS in vertical sections showing the inner plexiform layer (IPL), the ganglion cell layer (GCL) and the nerve fiber layer (NFL). ( Top row ) Double immunostaining with α1C subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). RGC axons (arrowhead) as well as putative Müller and neuronal cell processes in the IPL showed immunostaining. Control preadsorption of α1C antibody with the immunization peptide showed no staining. ( Second row ) Double immunostaining with α1D subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Numerous processes in the IPL as well as the RGC axons throughout the NFL (arrowhead) were also labelled. Control preadsorption of α1D antibody with the immunization peptide showed no staining. ( Third row ) Double immunostaining with <t>α1B</t> subunit and RBPMS antibodies shows colocalization in RGC somata (filled arrow). Processes in the IPL, putative displaced amacrine cells in the GCL (open arrows) and RGC axons throughout the NFL (arrowheads) showed immunostaining. Control preadsorption of α1B antibody with the immunization peptide showed no staining. ( Bottom row ) Double immunostaining with α1A subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Labelling in the IPL and in putative displaced amacrine cells in the GCL (open arrows) was also seen. Control preadsorption of α1A antibody with the immunization peptide showed no staining. Scale bar is 20 µm.
    Anti Ca V 2 2 Cacna1b Antibody Voltage Dependent N Type Calcium Channel Subunit α 1b, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti ca v 2 2 cacna1b antibody voltage dependent n type calcium channel subunit α 1b/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti ca v 2 2 cacna1b antibody voltage dependent n type calcium channel subunit α 1b - by Bioz Stars, 2023-01
    94/100 stars
      Buy from Supplier

    94
    Alomone Labs rabbit anti n type calcium channel
    Ca channel α 1 subunits co-express with the ganglion cell antibody RBPMS in vertical sections showing the inner plexiform layer (IPL), the ganglion cell layer (GCL) and the nerve fiber layer (NFL). ( Top row ) Double immunostaining with α1C subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). RGC axons (arrowhead) as well as putative Müller and neuronal cell processes in the IPL showed immunostaining. Control preadsorption of α1C antibody with the immunization peptide showed no staining. ( Second row ) Double immunostaining with α1D subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Numerous processes in the IPL as well as the RGC axons throughout the NFL (arrowhead) were also labelled. Control preadsorption of α1D antibody with the immunization peptide showed no staining. ( Third row ) Double immunostaining with <t>α1B</t> subunit and RBPMS antibodies shows colocalization in RGC somata (filled arrow). Processes in the IPL, putative displaced amacrine cells in the GCL (open arrows) and RGC axons throughout the NFL (arrowheads) showed immunostaining. Control preadsorption of α1B antibody with the immunization peptide showed no staining. ( Bottom row ) Double immunostaining with α1A subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Labelling in the IPL and in putative displaced amacrine cells in the GCL (open arrows) was also seen. Control preadsorption of α1A antibody with the immunization peptide showed no staining. Scale bar is 20 µm.
    Rabbit Anti N Type Calcium Channel, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti n type calcium channel/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti n type calcium channel - by Bioz Stars, 2023-01
    94/100 stars
      Buy from Supplier

    94
    Alomone Labs anti cacna1b cav2 2 antibody
    Ca channel α 1 subunits co-express with the ganglion cell antibody RBPMS in vertical sections showing the inner plexiform layer (IPL), the ganglion cell layer (GCL) and the nerve fiber layer (NFL). ( Top row ) Double immunostaining with α1C subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). RGC axons (arrowhead) as well as putative Müller and neuronal cell processes in the IPL showed immunostaining. Control preadsorption of α1C antibody with the immunization peptide showed no staining. ( Second row ) Double immunostaining with α1D subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Numerous processes in the IPL as well as the RGC axons throughout the NFL (arrowhead) were also labelled. Control preadsorption of α1D antibody with the immunization peptide showed no staining. ( Third row ) Double immunostaining with <t>α1B</t> subunit and RBPMS antibodies shows colocalization in RGC somata (filled arrow). Processes in the IPL, putative displaced amacrine cells in the GCL (open arrows) and RGC axons throughout the NFL (arrowheads) showed immunostaining. Control preadsorption of α1B antibody with the immunization peptide showed no staining. ( Bottom row ) Double immunostaining with α1A subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Labelling in the IPL and in putative displaced amacrine cells in the GCL (open arrows) was also seen. Control preadsorption of α1A antibody with the immunization peptide showed no staining. Scale bar is 20 µm.
    Anti Cacna1b Cav2 2 Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti cacna1b cav2 2 antibody/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti cacna1b cav2 2 antibody - by Bioz Stars, 2023-01
    94/100 stars
      Buy from Supplier

    94
    Alomone Labs rabbit anti ca v 2 2 antibody
    Ca channel α 1 subunits co-express with the ganglion cell antibody RBPMS in vertical sections showing the inner plexiform layer (IPL), the ganglion cell layer (GCL) and the nerve fiber layer (NFL). ( Top row ) Double immunostaining with α1C subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). RGC axons (arrowhead) as well as putative Müller and neuronal cell processes in the IPL showed immunostaining. Control preadsorption of α1C antibody with the immunization peptide showed no staining. ( Second row ) Double immunostaining with α1D subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Numerous processes in the IPL as well as the RGC axons throughout the NFL (arrowhead) were also labelled. Control preadsorption of α1D antibody with the immunization peptide showed no staining. ( Third row ) Double immunostaining with <t>α1B</t> subunit and RBPMS antibodies shows colocalization in RGC somata (filled arrow). Processes in the IPL, putative displaced amacrine cells in the GCL (open arrows) and RGC axons throughout the NFL (arrowheads) showed immunostaining. Control preadsorption of α1B antibody with the immunization peptide showed no staining. ( Bottom row ) Double immunostaining with α1A subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Labelling in the IPL and in putative displaced amacrine cells in the GCL (open arrows) was also seen. Control preadsorption of α1A antibody with the immunization peptide showed no staining. Scale bar is 20 µm.
    Rabbit Anti Ca V 2 2 Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti ca v 2 2 antibody/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit anti ca v 2 2 antibody - by Bioz Stars, 2023-01
    94/100 stars
      Buy from Supplier

    Image Search Results


    Primary antibodies used in the present study.

    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    Article Title: Silencing the ACAT1 Gene in Human SH-SY5Y Neuroblastoma Cells Inhibits the Expression of Cyclo-Oxygenase 2 (COX2) and Reduces β-Amyloid-Induced Toxicity Due to Activation of Protein Kinase C (PKC) and ERK

    doi: 10.12659/MSM.912862

    Figure Lengend Snippet: Primary antibodies used in the present study.

    Article Snippet: Rabbit anti-Cacna1b , 1: 1000 , Alomone Labs, Jerusalem, Israel.

    Techniques:

    Effects of knockdown ACAT1 on CACNAs, PKC, and ERK phosphorylation and in Aβ-induced SH-SY5Y cells. ( A ) Western blot results showed that the relative expression of CACNA1b and CACNA2d1 was increased significantly, while the total PKC and the ratio of phospho-ERK (p-ERK)/ERK were decreased significantly after Aβ 25-35 treatment. ( B ) Knockdown of ACAT1 rescued the reduction of PKC and phosphorylation level of ERK, and also retarded the upregulation of CACNA1b and CACNA2d1 induced by Aβ. (** P <0.01 and * P <0.05).

    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    Article Title: Silencing the ACAT1 Gene in Human SH-SY5Y Neuroblastoma Cells Inhibits the Expression of Cyclo-Oxygenase 2 (COX2) and Reduces β-Amyloid-Induced Toxicity Due to Activation of Protein Kinase C (PKC) and ERK

    doi: 10.12659/MSM.912862

    Figure Lengend Snippet: Effects of knockdown ACAT1 on CACNAs, PKC, and ERK phosphorylation and in Aβ-induced SH-SY5Y cells. ( A ) Western blot results showed that the relative expression of CACNA1b and CACNA2d1 was increased significantly, while the total PKC and the ratio of phospho-ERK (p-ERK)/ERK were decreased significantly after Aβ 25-35 treatment. ( B ) Knockdown of ACAT1 rescued the reduction of PKC and phosphorylation level of ERK, and also retarded the upregulation of CACNA1b and CACNA2d1 induced by Aβ. (** P <0.01 and * P <0.05).

    Article Snippet: Rabbit anti-Cacna1b , 1: 1000 , Alomone Labs, Jerusalem, Israel.

    Techniques: Western Blot, Expressing

    Primer sequences.

    Journal: Evidence-based Complementary and Alternative Medicine : eCAM

    Article Title: Upregulation of N-Type Voltage-Gated Calcium Channels Induces Neuropathic Pain in Experimental Autoimmune Neuritis

    doi: 10.1155/2022/8547095

    Figure Lengend Snippet: Primer sequences.

    Article Snippet: On completion of a 1 h blocking step with 5% skimmed milk at ambient temperature, primary antibodies iNOS (ab49999, Abcam, UK), MCP-1 (ab7202, Abcam, UK), and Cav2.2 (ACC-002, AlomoneLabs, Israel) were served for overnight coincubation with the membrane at 4°C.

    Techniques: Sequencing

    Effect of Cav2.2 on clinical score and sciatic nerve tissue of rats. (a) Clinical score record of rats during 18 days of immunization; (b) changes in body weight of rats during 18 days of immunization; (c) luxol fast blue (LFB) staining-based observation of the degree of cell infiltration and demyelination in sciatic nerve tissue of rats on the 18 th day of immunization. ∗∗ P < 0.01 vs. control group, ## P < 0.01 vs. EAN-shRNA group.

    Journal: Evidence-based Complementary and Alternative Medicine : eCAM

    Article Title: Upregulation of N-Type Voltage-Gated Calcium Channels Induces Neuropathic Pain in Experimental Autoimmune Neuritis

    doi: 10.1155/2022/8547095

    Figure Lengend Snippet: Effect of Cav2.2 on clinical score and sciatic nerve tissue of rats. (a) Clinical score record of rats during 18 days of immunization; (b) changes in body weight of rats during 18 days of immunization; (c) luxol fast blue (LFB) staining-based observation of the degree of cell infiltration and demyelination in sciatic nerve tissue of rats on the 18 th day of immunization. ∗∗ P < 0.01 vs. control group, ## P < 0.01 vs. EAN-shRNA group.

    Article Snippet: On completion of a 1 h blocking step with 5% skimmed milk at ambient temperature, primary antibodies iNOS (ab49999, Abcam, UK), MCP-1 (ab7202, Abcam, UK), and Cav2.2 (ACC-002, AlomoneLabs, Israel) were served for overnight coincubation with the membrane at 4°C.

    Techniques: Staining, shRNA

    Effect of Cav2.2 on allodynia in rats. (a–d) Measurement of withdrawal threshold to mechanical (a), thermal (b), and cold (c) stimulation, and mechanical hyperalgesia threshold (d) during 18 days of immunization. ∗∗ P < 0.01 vs. Control group, ## P < 0.01 vs. EAN-shRNA group.

    Journal: Evidence-based Complementary and Alternative Medicine : eCAM

    Article Title: Upregulation of N-Type Voltage-Gated Calcium Channels Induces Neuropathic Pain in Experimental Autoimmune Neuritis

    doi: 10.1155/2022/8547095

    Figure Lengend Snippet: Effect of Cav2.2 on allodynia in rats. (a–d) Measurement of withdrawal threshold to mechanical (a), thermal (b), and cold (c) stimulation, and mechanical hyperalgesia threshold (d) during 18 days of immunization. ∗∗ P < 0.01 vs. Control group, ## P < 0.01 vs. EAN-shRNA group.

    Article Snippet: On completion of a 1 h blocking step with 5% skimmed milk at ambient temperature, primary antibodies iNOS (ab49999, Abcam, UK), MCP-1 (ab7202, Abcam, UK), and Cav2.2 (ACC-002, AlomoneLabs, Israel) were served for overnight coincubation with the membrane at 4°C.

    Techniques: shRNA

    Effect of Cav2.2 on rat inflammatory response. (a) ELISA-based measurement of IL-6 and TNF- α expression in rat serum; (b) qRT-PCR-based measurement of mRNA expression of iNOS, MCP-1, and Cav2.2 in rat sciatic nerve; (c) western blot-based measurement of protein expression of iNOS, MCP-1, and Cav2.2 in rat sciatic nerve. ∗ P < 0.05 and ∗∗ P < 0.01 vs. control group, # P < 0.05 and ## P < 0.01 vs. EAN-shRNA group.

    Journal: Evidence-based Complementary and Alternative Medicine : eCAM

    Article Title: Upregulation of N-Type Voltage-Gated Calcium Channels Induces Neuropathic Pain in Experimental Autoimmune Neuritis

    doi: 10.1155/2022/8547095

    Figure Lengend Snippet: Effect of Cav2.2 on rat inflammatory response. (a) ELISA-based measurement of IL-6 and TNF- α expression in rat serum; (b) qRT-PCR-based measurement of mRNA expression of iNOS, MCP-1, and Cav2.2 in rat sciatic nerve; (c) western blot-based measurement of protein expression of iNOS, MCP-1, and Cav2.2 in rat sciatic nerve. ∗ P < 0.05 and ∗∗ P < 0.01 vs. control group, # P < 0.05 and ## P < 0.01 vs. EAN-shRNA group.

    Article Snippet: On completion of a 1 h blocking step with 5% skimmed milk at ambient temperature, primary antibodies iNOS (ab49999, Abcam, UK), MCP-1 (ab7202, Abcam, UK), and Cav2.2 (ACC-002, AlomoneLabs, Israel) were served for overnight coincubation with the membrane at 4°C.

    Techniques: Enzyme-linked Immunosorbent Assay, Expressing, Quantitative RT-PCR, Western Blot, shRNA

    Ca channel α 1 subunits co-express with the ganglion cell antibody RBPMS in vertical sections showing the inner plexiform layer (IPL), the ganglion cell layer (GCL) and the nerve fiber layer (NFL). ( Top row ) Double immunostaining with α1C subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). RGC axons (arrowhead) as well as putative Müller and neuronal cell processes in the IPL showed immunostaining. Control preadsorption of α1C antibody with the immunization peptide showed no staining. ( Second row ) Double immunostaining with α1D subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Numerous processes in the IPL as well as the RGC axons throughout the NFL (arrowhead) were also labelled. Control preadsorption of α1D antibody with the immunization peptide showed no staining. ( Third row ) Double immunostaining with α1B subunit and RBPMS antibodies shows colocalization in RGC somata (filled arrow). Processes in the IPL, putative displaced amacrine cells in the GCL (open arrows) and RGC axons throughout the NFL (arrowheads) showed immunostaining. Control preadsorption of α1B antibody with the immunization peptide showed no staining. ( Bottom row ) Double immunostaining with α1A subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Labelling in the IPL and in putative displaced amacrine cells in the GCL (open arrows) was also seen. Control preadsorption of α1A antibody with the immunization peptide showed no staining. Scale bar is 20 µm.

    Journal: PLoS ONE

    Article Title: Differential Calcium Signaling Mediated by Voltage-Gated Calcium Channels in Rat Retinal Ganglion Cells and Their Unmyelinated Axons

    doi: 10.1371/journal.pone.0084507

    Figure Lengend Snippet: Ca channel α 1 subunits co-express with the ganglion cell antibody RBPMS in vertical sections showing the inner plexiform layer (IPL), the ganglion cell layer (GCL) and the nerve fiber layer (NFL). ( Top row ) Double immunostaining with α1C subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). RGC axons (arrowhead) as well as putative Müller and neuronal cell processes in the IPL showed immunostaining. Control preadsorption of α1C antibody with the immunization peptide showed no staining. ( Second row ) Double immunostaining with α1D subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Numerous processes in the IPL as well as the RGC axons throughout the NFL (arrowhead) were also labelled. Control preadsorption of α1D antibody with the immunization peptide showed no staining. ( Third row ) Double immunostaining with α1B subunit and RBPMS antibodies shows colocalization in RGC somata (filled arrow). Processes in the IPL, putative displaced amacrine cells in the GCL (open arrows) and RGC axons throughout the NFL (arrowheads) showed immunostaining. Control preadsorption of α1B antibody with the immunization peptide showed no staining. ( Bottom row ) Double immunostaining with α1A subunit and RBPMS antibodies shows colocalization in the RGC somata (filled arrow). Labelling in the IPL and in putative displaced amacrine cells in the GCL (open arrows) was also seen. Control preadsorption of α1A antibody with the immunization peptide showed no staining. Scale bar is 20 µm.

    Article Snippet: The following polyclonal antibodies were used to obtain staining of the α1 subunits: α1C (Cav1.2, Alomone, ACC-003, 1∶1000, Jerusalem, Israel), α1D (Cav1.3, Sigma, C1728, St. Louis, MO, 1∶100), α1A (Cav2.1, Synaptic Systems, 152–103, 1∶7500, Göttingen, Germany), α1B (Cav2.2, Alomone, ACC-002, 1∶1000, Jerusalem, Israel).

    Techniques: Double Immunostaining, Immunostaining, Staining

    R at wholemount retina labelled with RBPMS (red), α1B VGCC subunit (green), and NF-M (white) antibodies. α1B colocalized with RBPMS in RGC somata (filled arrow), NF-M in RGC axons (arrowhead) and putative displaced amacrine cells (open arrow). Stack of six optical sections each of 0.3 µm thickness. Scale bar is 20 µm.

    Journal: PLoS ONE

    Article Title: Differential Calcium Signaling Mediated by Voltage-Gated Calcium Channels in Rat Retinal Ganglion Cells and Their Unmyelinated Axons

    doi: 10.1371/journal.pone.0084507

    Figure Lengend Snippet: R at wholemount retina labelled with RBPMS (red), α1B VGCC subunit (green), and NF-M (white) antibodies. α1B colocalized with RBPMS in RGC somata (filled arrow), NF-M in RGC axons (arrowhead) and putative displaced amacrine cells (open arrow). Stack of six optical sections each of 0.3 µm thickness. Scale bar is 20 µm.

    Article Snippet: The following polyclonal antibodies were used to obtain staining of the α1 subunits: α1C (Cav1.2, Alomone, ACC-003, 1∶1000, Jerusalem, Israel), α1D (Cav1.3, Sigma, C1728, St. Louis, MO, 1∶100), α1A (Cav2.1, Synaptic Systems, 152–103, 1∶7500, Göttingen, Germany), α1B (Cav2.2, Alomone, ACC-002, 1∶1000, Jerusalem, Israel).

    Techniques: