• Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 93
    Name:
    CA2 Antibody
    Description:
    Carbonic anhydrases CA are a family of ancient zinc metalloenzymes found in almost all living organisms All CA can be divided into 3 distinct classes α β and γ that evolved independently and have no significant homology in sequence and overall folding All functional CA catalyze the reversible hydration of CO2 into HCO3 and H and contain a zinc atom in the active sites essential for catalysis There are many isoforms of CA in mammals and they all belong to the α class 1 2 CA2 is a cytosolic member of the α class It is the most widely distributed isoform among the mammalian CAs 1 Defects in CA2 are associated with osteopetrosis and renal tubular acidosis 3 5 Elevated expression of CA2 is observed in patients with Alzheimer s disease and the developing brains of Down syndrome patients 6 7 CA2 is also overexpressed in Gastrointestinal Stromal Tumors GISTs and is considered a useful marker for diagnosis 8 Recently CA2 was reported to facilitate transporter activity of the monocarboxylate transporter isoform 1 and 4 MCT1 4 independent of its own catalytic activity 9 10
    Catalog Number:
    8612
    Price:
    None
    Applications:
    Western Blot, Immunoprecipitation
    Category:
    Primary Antibodies
    Source:
    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Lys169 of human CA2 protein. Antibodies are purified by protein A and peptide affinity chromatography.
    Reactivity:
    Human
    Buy from Supplier


    Structured Review

    Cell Signaling Technology Inc ca2
    Dynamics of <t>Ca2+</t> concentrations on the network
    Carbonic anhydrases CA are a family of ancient zinc metalloenzymes found in almost all living organisms All CA can be divided into 3 distinct classes α β and γ that evolved independently and have no significant homology in sequence and overall folding All functional CA catalyze the reversible hydration of CO2 into HCO3 and H and contain a zinc atom in the active sites essential for catalysis There are many isoforms of CA in mammals and they all belong to the α class 1 2 CA2 is a cytosolic member of the α class It is the most widely distributed isoform among the mammalian CAs 1 Defects in CA2 are associated with osteopetrosis and renal tubular acidosis 3 5 Elevated expression of CA2 is observed in patients with Alzheimer s disease and the developing brains of Down syndrome patients 6 7 CA2 is also overexpressed in Gastrointestinal Stromal Tumors GISTs and is considered a useful marker for diagnosis 8 Recently CA2 was reported to facilitate transporter activity of the monocarboxylate transporter isoform 1 and 4 MCT1 4 independent of its own catalytic activity 9 10
    https://www.bioz.com/result/ca2/product/Cell Signaling Technology Inc
    Average 93 stars, based on 5 article reviews
    Price from $9.99 to $1999.99
    ca2 - by Bioz Stars, 2020-11
    93/100 stars

    Images

    1) Product Images from "The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses"

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    Journal: PLoS Computational Biology

    doi: 10.1371/journal.pcbi.1005295

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D
    Figure Legend Snippet: Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D

    Techniques Used:

    Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D
    Figure Legend Snippet: Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Supporting Information Circular waves in a noise-free model emerge from highly sensitive cells. Simultaneous changes in ccyt (left panel) and cER (right panel) have been shown. Non-self-oscillating cells synchronize with their oscillating neighbors and produces spiral waves. Independent evolution of the cytoplasmic Ca2+ concentrations ccyt without gap junctional coupling (d = 0) in the random model. Bursting phenomena with moderate gap junctional coupling in the random model. Rapid synchronization with high gap junctional coupling in the random model and appearance of spiraling phenomena. Wave propagation in the random model in a highly linked graph. Wave propagation in the random model in a poorly linked graph. Wave propagation in the random model with holes. Appearance of spirals in a noise-free model with three highly sensitive zones. Appearance of spirals in a noise-free model with two highly sensitive zones. A sensitive random model with low noise evokes spirals. A sensitive random model with low noise and an additional sensitive central zone produces concentric circular waves. Setting one parameter above the “physiological” limit in the random model with low noise results in non-organized wave propagation and spirals. Wave propagation in the random model with Ca2+ coupling and no InsP3 coupling. Wave propagation in the random model with InsP3 coupling and no Ca2+ coupling. Wave propagation in the random model with InsP3 coupling and Ca2+ coupling. Wave propagation in the deterministic model with CR. Adjunction of CR in the random model helps synchronization.
    Figure Legend Snippet: Supporting Information Circular waves in a noise-free model emerge from highly sensitive cells. Simultaneous changes in ccyt (left panel) and cER (right panel) have been shown. Non-self-oscillating cells synchronize with their oscillating neighbors and produces spiral waves. Independent evolution of the cytoplasmic Ca2+ concentrations ccyt without gap junctional coupling (d = 0) in the random model. Bursting phenomena with moderate gap junctional coupling in the random model. Rapid synchronization with high gap junctional coupling in the random model and appearance of spiraling phenomena. Wave propagation in the random model in a highly linked graph. Wave propagation in the random model in a poorly linked graph. Wave propagation in the random model with holes. Appearance of spirals in a noise-free model with three highly sensitive zones. Appearance of spirals in a noise-free model with two highly sensitive zones. A sensitive random model with low noise evokes spirals. A sensitive random model with low noise and an additional sensitive central zone produces concentric circular waves. Setting one parameter above the “physiological” limit in the random model with low noise results in non-organized wave propagation and spirals. Wave propagation in the random model with Ca2+ coupling and no InsP3 coupling. Wave propagation in the random model with InsP3 coupling and no Ca2+ coupling. Wave propagation in the random model with InsP3 coupling and Ca2+ coupling. Wave propagation in the deterministic model with CR. Adjunction of CR in the random model helps synchronization.

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D
    Figure Legend Snippet: Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Supporting Information Circular waves in a noise-free model emerge from highly sensitive cells. Simultaneous changes in ccyt (left panel) and cER (right panel) have been shown. Non-self-oscillating cells synchronize with their oscillating neighbors and produces spiral waves. Independent evolution of the cytoplasmic Ca2+ concentrations ccyt without gap junctional coupling (d = 0) in the random model. Bursting phenomena with moderate gap junctional coupling in the random model. Rapid synchronization with high gap junctional coupling in the random model and appearance of spiraling phenomena. Wave propagation in the random model in a highly linked graph. Wave propagation in the random model in a poorly linked graph. Wave propagation in the random model with holes. Appearance of spirals in a noise-free model with three highly sensitive zones. Appearance of spirals in a noise-free model with two highly sensitive zones. A sensitive random model with low noise evokes spirals. A sensitive random model with low noise and an additional sensitive central zone produces concentric circular waves. Setting one parameter above the “physiological” limit in the random model with low noise results in non-organized wave propagation and spirals. Wave propagation in the random model with Ca2+ coupling and no InsP3 coupling. Wave propagation in the random model with InsP3 coupling and no Ca2+ coupling. Wave propagation in the random model with InsP3 coupling and Ca2+ coupling. Wave propagation in the deterministic model with CR. Adjunction of CR in the random model helps synchronization. μ i I P 3 , m a x
    Figure Legend Snippet: Supporting Information Circular waves in a noise-free model emerge from highly sensitive cells. Simultaneous changes in ccyt (left panel) and cER (right panel) have been shown. Non-self-oscillating cells synchronize with their oscillating neighbors and produces spiral waves. Independent evolution of the cytoplasmic Ca2+ concentrations ccyt without gap junctional coupling (d = 0) in the random model. Bursting phenomena with moderate gap junctional coupling in the random model. Rapid synchronization with high gap junctional coupling in the random model and appearance of spiraling phenomena. Wave propagation in the random model in a highly linked graph. Wave propagation in the random model in a poorly linked graph. Wave propagation in the random model with holes. Appearance of spirals in a noise-free model with three highly sensitive zones. Appearance of spirals in a noise-free model with two highly sensitive zones. A sensitive random model with low noise evokes spirals. A sensitive random model with low noise and an additional sensitive central zone produces concentric circular waves. Setting one parameter above the “physiological” limit in the random model with low noise results in non-organized wave propagation and spirals. Wave propagation in the random model with Ca2+ coupling and no InsP3 coupling. Wave propagation in the random model with InsP3 coupling and no Ca2+ coupling. Wave propagation in the random model with InsP3 coupling and Ca2+ coupling. Wave propagation in the deterministic model with CR. Adjunction of CR in the random model helps synchronization. μ i I P 3 , m a x

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    2) Product Images from "The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses"

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    Journal: PLoS Computational Biology

    doi: 10.1371/journal.pcbi.1005295

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D
    Figure Legend Snippet: Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D

    Techniques Used:

    Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D
    Figure Legend Snippet: Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Supporting Information Circular waves in a noise-free model emerge from highly sensitive cells. Simultaneous changes in ccyt (left panel) and cER (right panel) have been shown. Non-self-oscillating cells synchronize with their oscillating neighbors and produces spiral waves. Independent evolution of the cytoplasmic Ca2+ concentrations ccyt without gap junctional coupling (d = 0) in the random model. Bursting phenomena with moderate gap junctional coupling in the random model. Rapid synchronization with high gap junctional coupling in the random model and appearance of spiraling phenomena. Wave propagation in the random model in a highly linked graph. Wave propagation in the random model in a poorly linked graph. Wave propagation in the random model with holes. Appearance of spirals in a noise-free model with three highly sensitive zones. Appearance of spirals in a noise-free model with two highly sensitive zones. A sensitive random model with low noise evokes spirals. A sensitive random model with low noise and an additional sensitive central zone produces concentric circular waves. Setting one parameter above the “physiological” limit in the random model with low noise results in non-organized wave propagation and spirals. Wave propagation in the random model with Ca2+ coupling and no InsP3 coupling. Wave propagation in the random model with InsP3 coupling and no Ca2+ coupling. Wave propagation in the random model with InsP3 coupling and Ca2+ coupling. Wave propagation in the deterministic model with CR. Adjunction of CR in the random model helps synchronization.
    Figure Legend Snippet: Supporting Information Circular waves in a noise-free model emerge from highly sensitive cells. Simultaneous changes in ccyt (left panel) and cER (right panel) have been shown. Non-self-oscillating cells synchronize with their oscillating neighbors and produces spiral waves. Independent evolution of the cytoplasmic Ca2+ concentrations ccyt without gap junctional coupling (d = 0) in the random model. Bursting phenomena with moderate gap junctional coupling in the random model. Rapid synchronization with high gap junctional coupling in the random model and appearance of spiraling phenomena. Wave propagation in the random model in a highly linked graph. Wave propagation in the random model in a poorly linked graph. Wave propagation in the random model with holes. Appearance of spirals in a noise-free model with three highly sensitive zones. Appearance of spirals in a noise-free model with two highly sensitive zones. A sensitive random model with low noise evokes spirals. A sensitive random model with low noise and an additional sensitive central zone produces concentric circular waves. Setting one parameter above the “physiological” limit in the random model with low noise results in non-organized wave propagation and spirals. Wave propagation in the random model with Ca2+ coupling and no InsP3 coupling. Wave propagation in the random model with InsP3 coupling and no Ca2+ coupling. Wave propagation in the random model with InsP3 coupling and Ca2+ coupling. Wave propagation in the deterministic model with CR. Adjunction of CR in the random model helps synchronization.

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D
    Figure Legend Snippet: Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Supporting Information Circular waves in a noise-free model emerge from highly sensitive cells. Simultaneous changes in ccyt (left panel) and cER (right panel) have been shown. Non-self-oscillating cells synchronize with their oscillating neighbors and produces spiral waves. Independent evolution of the cytoplasmic Ca2+ concentrations ccyt without gap junctional coupling (d = 0) in the random model. Bursting phenomena with moderate gap junctional coupling in the random model. Rapid synchronization with high gap junctional coupling in the random model and appearance of spiraling phenomena. Wave propagation in the random model in a highly linked graph. Wave propagation in the random model in a poorly linked graph. Wave propagation in the random model with holes. Appearance of spirals in a noise-free model with three highly sensitive zones. Appearance of spirals in a noise-free model with two highly sensitive zones. A sensitive random model with low noise evokes spirals. A sensitive random model with low noise and an additional sensitive central zone produces concentric circular waves. Setting one parameter above the “physiological” limit in the random model with low noise results in non-organized wave propagation and spirals. Wave propagation in the random model with Ca2+ coupling and no InsP3 coupling. Wave propagation in the random model with InsP3 coupling and no Ca2+ coupling. Wave propagation in the random model with InsP3 coupling and Ca2+ coupling. Wave propagation in the deterministic model with CR. Adjunction of CR in the random model helps synchronization. μ i I P 3 , m a x
    Figure Legend Snippet: Supporting Information Circular waves in a noise-free model emerge from highly sensitive cells. Simultaneous changes in ccyt (left panel) and cER (right panel) have been shown. Non-self-oscillating cells synchronize with their oscillating neighbors and produces spiral waves. Independent evolution of the cytoplasmic Ca2+ concentrations ccyt without gap junctional coupling (d = 0) in the random model. Bursting phenomena with moderate gap junctional coupling in the random model. Rapid synchronization with high gap junctional coupling in the random model and appearance of spiraling phenomena. Wave propagation in the random model in a highly linked graph. Wave propagation in the random model in a poorly linked graph. Wave propagation in the random model with holes. Appearance of spirals in a noise-free model with three highly sensitive zones. Appearance of spirals in a noise-free model with two highly sensitive zones. A sensitive random model with low noise evokes spirals. A sensitive random model with low noise and an additional sensitive central zone produces concentric circular waves. Setting one parameter above the “physiological” limit in the random model with low noise results in non-organized wave propagation and spirals. Wave propagation in the random model with Ca2+ coupling and no InsP3 coupling. Wave propagation in the random model with InsP3 coupling and no Ca2+ coupling. Wave propagation in the random model with InsP3 coupling and Ca2+ coupling. Wave propagation in the deterministic model with CR. Adjunction of CR in the random model helps synchronization. μ i I P 3 , m a x

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Dynamics of Ca2+ concentrations on the network
    Figure Legend Snippet: Dynamics of Ca2+ concentrations on the network

    Techniques Used:

    Related Articles

    Western Blot:

    Article Title: Specific Detection of CD56 (NCAM) Isoforms for the Identification of Aggressive Malignant Neoplasms with Progressive Development
    Article Snippet: .. For the detection of Ca2+ -dependent phosphorylated kinases, whole protein extracts from INA6 cells transfected with individual CD56 isoforms (see above) were tested by Western blotting using phospho-antibody sampler kits (Cell Signaling, Danvers, MA) specific for the Akt-pathway, the erk1/2 pathway, the p38 MAP kinase pathway, the SAPK/JNK pathway, as well as for CamKII, phospho-CamKII, and phospho-PKA C. The detection of intracellular calcium was performed by loading CD56-transfected INA-6 cells with the calcium indicator Fluo-4 following the instructions of the manufacturer (Molecular Probes, Invitrogen, Heidelberg, Germany). .. Comparisons were made using the Mann-Whitney U -test and the SPSS for Windows software package (SPSS Inc., Chicago, IL).

    Incubation:

    Article Title: ?2 Adrenergic Receptor, Protein Kinase A (PKA) and c-Jun N-terminal Kinase (JNK) Signaling Pathways Mediate Tau Pathology in Alzheimer Disease Models *
    Article Snippet: .. Then the membranes were incubated with primary antibodies against phospho-tau (phospho-Ser-214 and phospho-Ser-262, Santa Cruz Biotechnology, Inc. and Invitrogen, respectively, and phospho-Thr-181, Abcam, MA) and tau (Sigma-Aldrich, MO); phospho- and total stress-activated protein kinase/JNK, GSK3α/β, Ca2+ /calmodulin-dependent protein kinase II, and ERK1/2 (Cell Signaling Technology, Inc.); γ-tubulin (Sigma-Aldrich); or synapsin I (Cell Signaling Technology, Inc.) at 4 °C overnight. ..

    Permeability:

    Article Title: Translational approaches: From fatty liver to non-alcoholic steatohepatitis
    Article Snippet: .. Adjacent mitochondria readily take up the released Ca2+ , and the acute Ca2+ overload results in changes in mitochondrial potential and opening of the permeability transition pores (PTPs)[ ] ensuring a potent cellular cell signal[ ]. ..

    Transfection:

    Article Title: Specific Detection of CD56 (NCAM) Isoforms for the Identification of Aggressive Malignant Neoplasms with Progressive Development
    Article Snippet: .. For the detection of Ca2+ -dependent phosphorylated kinases, whole protein extracts from INA6 cells transfected with individual CD56 isoforms (see above) were tested by Western blotting using phospho-antibody sampler kits (Cell Signaling, Danvers, MA) specific for the Akt-pathway, the erk1/2 pathway, the p38 MAP kinase pathway, the SAPK/JNK pathway, as well as for CamKII, phospho-CamKII, and phospho-PKA C. The detection of intracellular calcium was performed by loading CD56-transfected INA-6 cells with the calcium indicator Fluo-4 following the instructions of the manufacturer (Molecular Probes, Invitrogen, Heidelberg, Germany). .. Comparisons were made using the Mann-Whitney U -test and the SPSS for Windows software package (SPSS Inc., Chicago, IL).

    Similar Products

  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 93
    Cell Signaling Technology Inc ca2
    Dynamics of <t>Ca2+</t> concentrations on the network
    Ca2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ca2/product/Cell Signaling Technology Inc
    Average 93 stars, based on 5 article reviews
    Price from $9.99 to $1999.99
    ca2 - by Bioz Stars, 2020-11
    93/100 stars
      Buy from Supplier

    88
    Cell Signaling Technology Inc mitochondrial ca2 uptake
    3.1. Isolated mitoplasts exhibit multiple distinct <t>Ca2+</t> currents that vary depending on the cell type chosen for isolation
    Mitochondrial Ca2 Uptake, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 88/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mitochondrial ca2 uptake/product/Cell Signaling Technology Inc
    Average 88 stars, based on 4 article reviews
    Price from $9.99 to $1999.99
    mitochondrial ca2 uptake - by Bioz Stars, 2020-11
    88/100 stars
      Buy from Supplier

    Image Search Results


    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Supporting Information Circular waves in a noise-free model emerge from highly sensitive cells. Simultaneous changes in ccyt (left panel) and cER (right panel) have been shown. Non-self-oscillating cells synchronize with their oscillating neighbors and produces spiral waves. Independent evolution of the cytoplasmic Ca2+ concentrations ccyt without gap junctional coupling (d = 0) in the random model. Bursting phenomena with moderate gap junctional coupling in the random model. Rapid synchronization with high gap junctional coupling in the random model and appearance of spiraling phenomena. Wave propagation in the random model in a highly linked graph. Wave propagation in the random model in a poorly linked graph. Wave propagation in the random model with holes. Appearance of spirals in a noise-free model with three highly sensitive zones. Appearance of spirals in a noise-free model with two highly sensitive zones. A sensitive random model with low noise evokes spirals. A sensitive random model with low noise and an additional sensitive central zone produces concentric circular waves. Setting one parameter above the “physiological” limit in the random model with low noise results in non-organized wave propagation and spirals. Wave propagation in the random model with Ca2+ coupling and no InsP3 coupling. Wave propagation in the random model with InsP3 coupling and no Ca2+ coupling. Wave propagation in the random model with InsP3 coupling and Ca2+ coupling. Wave propagation in the deterministic model with CR. Adjunction of CR in the random model helps synchronization.

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Supporting Information Circular waves in a noise-free model emerge from highly sensitive cells. Simultaneous changes in ccyt (left panel) and cER (right panel) have been shown. Non-self-oscillating cells synchronize with their oscillating neighbors and produces spiral waves. Independent evolution of the cytoplasmic Ca2+ concentrations ccyt without gap junctional coupling (d = 0) in the random model. Bursting phenomena with moderate gap junctional coupling in the random model. Rapid synchronization with high gap junctional coupling in the random model and appearance of spiraling phenomena. Wave propagation in the random model in a highly linked graph. Wave propagation in the random model in a poorly linked graph. Wave propagation in the random model with holes. Appearance of spirals in a noise-free model with three highly sensitive zones. Appearance of spirals in a noise-free model with two highly sensitive zones. A sensitive random model with low noise evokes spirals. A sensitive random model with low noise and an additional sensitive central zone produces concentric circular waves. Setting one parameter above the “physiological” limit in the random model with low noise results in non-organized wave propagation and spirals. Wave propagation in the random model with Ca2+ coupling and no InsP3 coupling. Wave propagation in the random model with InsP3 coupling and no Ca2+ coupling. Wave propagation in the random model with InsP3 coupling and Ca2+ coupling. Wave propagation in the deterministic model with CR. Adjunction of CR in the random model helps synchronization.

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Effect of the gap junctional coupling (d ) on Ca2+ waves in the noise-free models G D

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Supporting Information Circular waves in a noise-free model emerge from highly sensitive cells. Simultaneous changes in ccyt (left panel) and cER (right panel) have been shown. Non-self-oscillating cells synchronize with their oscillating neighbors and produces spiral waves. Independent evolution of the cytoplasmic Ca2+ concentrations ccyt without gap junctional coupling (d = 0) in the random model. Bursting phenomena with moderate gap junctional coupling in the random model. Rapid synchronization with high gap junctional coupling in the random model and appearance of spiraling phenomena. Wave propagation in the random model in a highly linked graph. Wave propagation in the random model in a poorly linked graph. Wave propagation in the random model with holes. Appearance of spirals in a noise-free model with three highly sensitive zones. Appearance of spirals in a noise-free model with two highly sensitive zones. A sensitive random model with low noise evokes spirals. A sensitive random model with low noise and an additional sensitive central zone produces concentric circular waves. Setting one parameter above the “physiological” limit in the random model with low noise results in non-organized wave propagation and spirals. Wave propagation in the random model with Ca2+ coupling and no InsP3 coupling. Wave propagation in the random model with InsP3 coupling and no Ca2+ coupling. Wave propagation in the random model with InsP3 coupling and Ca2+ coupling. Wave propagation in the deterministic model with CR. Adjunction of CR in the random model helps synchronization. μ i I P 3 , m a x

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Supporting Information Circular waves in a noise-free model emerge from highly sensitive cells. Simultaneous changes in ccyt (left panel) and cER (right panel) have been shown. Non-self-oscillating cells synchronize with their oscillating neighbors and produces spiral waves. Independent evolution of the cytoplasmic Ca2+ concentrations ccyt without gap junctional coupling (d = 0) in the random model. Bursting phenomena with moderate gap junctional coupling in the random model. Rapid synchronization with high gap junctional coupling in the random model and appearance of spiraling phenomena. Wave propagation in the random model in a highly linked graph. Wave propagation in the random model in a poorly linked graph. Wave propagation in the random model with holes. Appearance of spirals in a noise-free model with three highly sensitive zones. Appearance of spirals in a noise-free model with two highly sensitive zones. A sensitive random model with low noise evokes spirals. A sensitive random model with low noise and an additional sensitive central zone produces concentric circular waves. Setting one parameter above the “physiological” limit in the random model with low noise results in non-organized wave propagation and spirals. Wave propagation in the random model with Ca2+ coupling and no InsP3 coupling. Wave propagation in the random model with InsP3 coupling and no Ca2+ coupling. Wave propagation in the random model with InsP3 coupling and Ca2+ coupling. Wave propagation in the deterministic model with CR. Adjunction of CR in the random model helps synchronization. μ i I P 3 , m a x

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    Dynamics of Ca2+ concentrations on the network

    Journal: PLoS Computational Biology

    Article Title: The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca2+ Signals and the Harmonization of Ca2+-Related Cellular Responses

    doi: 10.1371/journal.pcbi.1005295

    Figure Lengend Snippet: Dynamics of Ca2+ concentrations on the network

    Article Snippet: Maintaining the low concentrations of Ca2+ in the cytoplasm against a 10,000-fold higher extracellular Ca2+ concentration, i.e. the strong trans-membrane electrochemical gradient of Ca2+ ions needed for proper cell signaling [ ] requires energy.

    Techniques:

    3.1. Isolated mitoplasts exhibit multiple distinct Ca2+ currents that vary depending on the cell type chosen for isolation

    Journal: Molecular and Cellular Endocrinology

    Article Title: Studying mitochondrial Ca2+ uptake - A revisit

    doi: 10.1016/j.mce.2011.10.033

    Figure Lengend Snippet: 3.1. Isolated mitoplasts exhibit multiple distinct Ca2+ currents that vary depending on the cell type chosen for isolation

    Article Snippet: Accordingly, mitochondrial Ca2+ uptake is considered as an important cellular process that is relevant for both physiological and pathological cell signaling ( ).

    Techniques: Isolation