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Concentration Assay
Control
Expressing
Immunohistochemistry
Labeling
Mutagenesis
Staining
Ubiquitin Proteomics
Emerging clinical applications of selected biomarkers in melanoma 
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List of selected tissue biomarkers in melanoma
Emerging clinical applications of selected biomarkers in melanoma 
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Immunohistochemcial evaluation of <t>BRAFV600E</t> mutation status in melanoma. Notes: ( A ) Melanoma cells with diffuse, cytoplasmic labeling with anti-BRAFV600E (IHC stain, chromagen AEC, ×400); ( B ) Focal labeling of melanoma cells with anti-BRAFV600E and the presence of tumor heterogeneity in a subset of tumors (IHC stain, chromagen AEC, ×400); ( C ) Melanoma cells with notable melanin pigment (H&E stain, ×400); ( D ) Melanoma cells negative for anti-BRAFV600E; Brown color in cytoplasm of melanoma cells is melanin pigment (*) and not DAB chromagen (IHC stain, DAB, ×400). Abbreviations: AEC, 3-amino-9-ethylcarbazole; DAB, diaminobenzidine; H&E, hematoxylin and eosin; IHC, immunohistochemistry.
Emerging clinical applications of selected biomarkers in melanoma 
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Immunohistochemcial evaluation of BAP-1 and <t>BRAFV600E</t> status in melanocytic lesions. Notes: ( A ) Melanocytic nevus composed of sheets of epithelioid-shaped melanocytes in the dermis (H&E stain, ×400); ( B ) Anti-BAP-1 demonstrates loss of nuclear expression in melanocytes (arrows) indicative of the presence of BAP-1 mutation (IHC stain, ×400); ( C ) Diffuse cytoplasmic expression of anti-BRAFV600E (IHC stain, ×400). Abbreviations: H&E, hematoxylin and eosin; IHC, immunohistochemistry.
Emerging clinical applications of selected biomarkers in melanoma Clinical, Cosmetic and Investigational Dermatology, 2015 Jan 01
"List of selected tissue biomarkers in melanoma"
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