autotaxin inhibitor screening kit  (Echelon Biosciences)


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    Structured Review

    Echelon Biosciences autotaxin inhibitor screening kit
    The <t>autotaxin</t> inhibitors HA-130 and PF-8380 did not impact tumor progression in a xenograft model of melanoma. Animals with melanoma tumors were treated with the indicated concentrations of either: HA-130 (A), PF-8380 (B) or dimethylformamide (DMF) solvent
    Autotaxin Inhibitor Screening Kit, supplied by Echelon Biosciences, used in various techniques. Bioz Stars score: 88/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/autotaxin inhibitor screening kit/product/Echelon Biosciences
    Average 88 stars, based on 3 article reviews
    Price from $9.99 to $1999.99
    autotaxin inhibitor screening kit - by Bioz Stars, 2022-10
    88/100 stars

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    1) Product Images from "Vinyl Sulfone Analogs of Lysophosphatidylcholine Irreversibly Inhibit Autotaxin and Prevent Angiogenesis in Melanoma"

    Article Title: Vinyl Sulfone Analogs of Lysophosphatidylcholine Irreversibly Inhibit Autotaxin and Prevent Angiogenesis in Melanoma

    Journal: Bioorganic & medicinal chemistry

    doi: 10.1016/j.bmc.2015.06.054

    The autotaxin inhibitors HA-130 and PF-8380 did not impact tumor progression in a xenograft model of melanoma. Animals with melanoma tumors were treated with the indicated concentrations of either: HA-130 (A), PF-8380 (B) or dimethylformamide (DMF) solvent
    Figure Legend Snippet: The autotaxin inhibitors HA-130 and PF-8380 did not impact tumor progression in a xenograft model of melanoma. Animals with melanoma tumors were treated with the indicated concentrations of either: HA-130 (A), PF-8380 (B) or dimethylformamide (DMF) solvent

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    Echelon Biosciences autotaxin inhibitor screening kit
    The <t>autotaxin</t> inhibitors HA-130 and PF-8380 did not impact tumor progression in a xenograft model of melanoma. Animals with melanoma tumors were treated with the indicated concentrations of either: HA-130 (A), PF-8380 (B) or dimethylformamide (DMF) solvent
    Autotaxin Inhibitor Screening Kit, supplied by Echelon Biosciences, used in various techniques. Bioz Stars score: 88/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/autotaxin inhibitor screening kit/product/Echelon Biosciences
    Average 88 stars, based on 4 article reviews
    Price from $9.99 to $1999.99
    autotaxin inhibitor screening kit - by Bioz Stars, 2022-10
    88/100 stars
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    The autotaxin inhibitors HA-130 and PF-8380 did not impact tumor progression in a xenograft model of melanoma. Animals with melanoma tumors were treated with the indicated concentrations of either: HA-130 (A), PF-8380 (B) or dimethylformamide (DMF) solvent

    Journal: Bioorganic & medicinal chemistry

    Article Title: Vinyl Sulfone Analogs of Lysophosphatidylcholine Irreversibly Inhibit Autotaxin and Prevent Angiogenesis in Melanoma

    doi: 10.1016/j.bmc.2015.06.054

    Figure Lengend Snippet: The autotaxin inhibitors HA-130 and PF-8380 did not impact tumor progression in a xenograft model of melanoma. Animals with melanoma tumors were treated with the indicated concentrations of either: HA-130 (A), PF-8380 (B) or dimethylformamide (DMF) solvent

    Article Snippet: ATX inhibition was performed using an ATX Inhibitor Screening Kit (K-4200, Echelon Biosciences, Inc. Salt Lake City, UT).

    Techniques:

    ATX inhibitors reduce the cell viability of MeWo melanoma cells, in contrast with chemotherapy. Cell viability was measured using CellTiter® Blue after treating cells with the indicated concentration of: CVS-16 ( 10b ), HA-130, PF-8380, dacarbazine

    Journal: Bioorganic & medicinal chemistry

    Article Title: Vinyl Sulfone Analogs of Lysophosphatidylcholine Irreversibly Inhibit Autotaxin and Prevent Angiogenesis in Melanoma

    doi: 10.1016/j.bmc.2015.06.054

    Figure Lengend Snippet: ATX inhibitors reduce the cell viability of MeWo melanoma cells, in contrast with chemotherapy. Cell viability was measured using CellTiter® Blue after treating cells with the indicated concentration of: CVS-16 ( 10b ), HA-130, PF-8380, dacarbazine

    Article Snippet: The inhibition of ATX by the vinyl sulfone ATX analogues CVS-18 ( 10a) and CVS-16 ( 10b ) was tested using an ATX inhibitor screening kit (Echelon Biosciences, Inc.) in a dose-response mode ( ).

    Techniques: Concentration Assay