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Image Search Results


(A) Gene targets of R-IRI from OMIM and GeneCards. (B) PCA of gene expression. (C) Heatmap of DEGs. (D) Volcano plot of DEGs. (E) Intersection of R-IRI signature genes.

Journal: Frontiers in Pharmacology

Article Title: Mechanistic elucidation of Wuling Powder targeting macrophage polarization to ameliorate renal ischemia-reperfusion injury via multidimensional computational systems pharmacology coupled with experimental validation

doi: 10.3389/fphar.2026.1811709

Figure Lengend Snippet: (A) Gene targets of R-IRI from OMIM and GeneCards. (B) PCA of gene expression. (C) Heatmap of DEGs. (D) Volcano plot of DEGs. (E) Intersection of R-IRI signature genes.

Article Snippet: In summary, this study clarified the specific mechanism by which Wuling Powder attenuates R-IRI by regulating macrophage polarization, providing new evidence for its clinical application.

Techniques: Gene Expression

GO and KEGG enrichment analysis. (A) Venn diagram of overlapping targets among WLP, MP and R-IRI, and their visualization of corresponding target protein structures. (B) Plot of GO functional enrichment analysis. (C) KEGG pathway enrichment analysis, integrating chord diagram and bubble plot.

Journal: Frontiers in Pharmacology

Article Title: Mechanistic elucidation of Wuling Powder targeting macrophage polarization to ameliorate renal ischemia-reperfusion injury via multidimensional computational systems pharmacology coupled with experimental validation

doi: 10.3389/fphar.2026.1811709

Figure Lengend Snippet: GO and KEGG enrichment analysis. (A) Venn diagram of overlapping targets among WLP, MP and R-IRI, and their visualization of corresponding target protein structures. (B) Plot of GO functional enrichment analysis. (C) KEGG pathway enrichment analysis, integrating chord diagram and bubble plot.

Article Snippet: In summary, this study clarified the specific mechanism by which Wuling Powder attenuates R-IRI by regulating macrophage polarization, providing new evidence for its clinical application.

Techniques: Functional Assay

Potential mechanism by which WLP regulates MP to alleviate R-IRI.

Journal: Frontiers in Pharmacology

Article Title: Mechanistic elucidation of Wuling Powder targeting macrophage polarization to ameliorate renal ischemia-reperfusion injury via multidimensional computational systems pharmacology coupled with experimental validation

doi: 10.3389/fphar.2026.1811709

Figure Lengend Snippet: Potential mechanism by which WLP regulates MP to alleviate R-IRI.

Article Snippet: In summary, this study clarified the specific mechanism by which Wuling Powder attenuates R-IRI by regulating macrophage polarization, providing new evidence for its clinical application.

Techniques: