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Journal: Cell Communication and Signaling : CCS
Article Title: Atorvastatin promotes lipid catabolism in colorectal cancer via FDFT1‒mediated inhibition of the PI3K/AKT pathway
doi: 10.1186/s12964-026-02802-6
Figure Lengend Snippet: ATST introduces ferroptosis‒like cell death in CRC A Protein expression levels of NRF2 and GPX4 B The expression of NRF2 in the cytoplasm and nucleus C mRNA expression level of NRF2, SLC7A11 and GPX4 D Changes in intracellular Fe 2+ content E Changes in intracellular GSH content F Changes in intracellular MDA content G TEM of colon tumours in AOM/DSS‒induced colon cancer mice. Scar bar :500 nm
Article Snippet: The MODEL and ATST groups of mice received an intraperitoneal injection of
Techniques: Expressing