rabbit anti d1 receptor antibody  (Alomone Labs)


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    Alomone Labs rabbit anti d1 receptor antibody
    Rabbit Anti D1 Receptor Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    rabbit anti d1 receptor antibody  (Alomone Labs)


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    Alomone Labs rabbit anti d1 receptor antibody
    Rabbit Anti D1 Receptor Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    adr 001 rrid ab 2039826  (Alomone Labs)


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    Alomone Labs adr 001 rrid ab 2039826
    Adr 001 Rrid Ab 2039826, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    rabbit polyclonal anti d1 receptor  (Alomone Labs)


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    Alomone Labs rabbit polyclonal anti d1 receptor
    Rabbit Polyclonal Anti D1 Receptor, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    adr 001 rrid ab 2039826  (Alomone Labs)


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    Alomone Labs adr 001 rrid ab 2039826
    Adr 001 Rrid Ab 2039826, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/adr 001 rrid ab 2039826/product/Alomone Labs
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    anti d1 antibody  (Alomone Labs)


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    Alomone Labs anti d1 antibody
    Anti D1 Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    d1r rabbit polyclonal adr  (Alomone Labs)


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    Alomone Labs d1r rabbit polyclonal adr
    Antibody information
    D1r Rabbit Polyclonal Adr, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    1) Product Images from "Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons"

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    Journal: Cerebral Cortex (New York, NY)

    doi: 10.1093/cercor/bhz078

    Antibody information
    Figure Legend Snippet: Antibody information

    Techniques Used:

    Proportion of neurons expressing dopamine receptors across cortical layers. (A) The density of different neuronal classes across cortical layers. (B) The density of neurons expressing D1Rs or D2Rs for each cortical layer. (C) D1R and D2R expression across FEF cortex. Tissue is from the same animal (Monkey 4) and is oriented with the pial surface at the top and white matter at the bottom. Scale bar = 100 μm.
    Figure Legend Snippet: Proportion of neurons expressing dopamine receptors across cortical layers. (A) The density of different neuronal classes across cortical layers. (B) The density of neurons expressing D1Rs or D2Rs for each cortical layer. (C) D1R and D2R expression across FEF cortex. Tissue is from the same animal (Monkey 4) and is oriented with the pial surface at the top and white matter at the bottom. Scale bar = 100 μm.

    Techniques Used: Expressing

    Proportion of neurogranin+ and SMI-32+ pyramidal neurons that express D1Rs or D2Rs. Significantly more neurogranin+ neurons and SMI-32+ neurons express D1Rs (black) than D2Rs (gray). *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts (Neurogranin+ N = 3028, P < 10−10; SMI32+ N = 225, P = 3.2 × 10−13). Bar heights and standard error bars are calculated from the across-animal mean proportions, and the exact values are described in the main text. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.
    Figure Legend Snippet: Proportion of neurogranin+ and SMI-32+ pyramidal neurons that express D1Rs or D2Rs. Significantly more neurogranin+ neurons and SMI-32+ neurons express D1Rs (black) than D2Rs (gray). *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts (Neurogranin+ N = 3028, P < 10−10; SMI32+ N = 225, P = 3.2 × 10−13). Bar heights and standard error bars are calculated from the across-animal mean proportions, and the exact values are described in the main text. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.

    Techniques Used:

    Distribution of dopamine receptors in pyramidal neuron populations across cortical layers. (A) The proportion of D1R-expressing neurogranin+ pyramidal neurons is larger than the proportion of D2R-expressing neurogranin+ neurons across all layers. This difference was statistically significant in layers II–V. Overall, the ratio of D1Rs to D2Rs decreases across cortical layers (right y-axis). (B) The proportion of D1R-expressing SMI-32+ pyramidal neurons is also larger than the proportion of D2R-expressing SMI-32+ neurons across all layers. This difference was statistically significant in layers II-III, and VI. *, **, and *** denote significance at the level of 0.05, 0.01, and 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Neurogranin+ N = 766, 111, 262, 575; P < 10−16, 0.0048, 9.39 × 10−8, 1.6 × 10−4 for layers II-III, IV, V, and VI, respectively. SMI-32+ N = 72, 31, 35, 73; P = 0.0023, 0.2, 0.09, and 0.0019 for layers II-III, IV, V, and VI respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.
    Figure Legend Snippet: Distribution of dopamine receptors in pyramidal neuron populations across cortical layers. (A) The proportion of D1R-expressing neurogranin+ pyramidal neurons is larger than the proportion of D2R-expressing neurogranin+ neurons across all layers. This difference was statistically significant in layers II–V. Overall, the ratio of D1Rs to D2Rs decreases across cortical layers (right y-axis). (B) The proportion of D1R-expressing SMI-32+ pyramidal neurons is also larger than the proportion of D2R-expressing SMI-32+ neurons across all layers. This difference was statistically significant in layers II-III, and VI. *, **, and *** denote significance at the level of 0.05, 0.01, and 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Neurogranin+ N = 766, 111, 262, 575; P < 10−16, 0.0048, 9.39 × 10−8, 1.6 × 10−4 for layers II-III, IV, V, and VI, respectively. SMI-32+ N = 72, 31, 35, 73; P = 0.0023, 0.2, 0.09, and 0.0019 for layers II-III, IV, V, and VI respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.

    Techniques Used: Expressing

    P -values of layer-versus-layer pairwise comparisons for  D1R  and D2R expression on different neuronal classes
    Figure Legend Snippet: P -values of layer-versus-layer pairwise comparisons for D1R and D2R expression on different neuronal classes

    Techniques Used: Expressing

    Proportion of inhibitory interneuron classes that express D1Rs or D2Rs. A significantly higher proportion of parvalbumin+ inhibitory interneurons express D2Rs than D1Rs. A significantly higher proportion of calbindin+ inhibitory interneurons express D1Rs compared with D2Rs. When pooling across interneuron classes, the proportion of D2R-expressing interneurons is significantly greater than the proportion of D1R-expressing interneurons. We did not perform a statistical comparison between D1R- and D2R-expressing somatostatin+ neurons because they were so rare. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determine using chi-squared tests calculated on total counts (Parvalbumin+ N = 635, P < 10−16; Calbindin+ N = 624, P = 5.7 × 10−5; Calretinin+ N = 648, P = 0.42). Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4; Somatostatin+ D1R, D2R = 3, 4.
    Figure Legend Snippet: Proportion of inhibitory interneuron classes that express D1Rs or D2Rs. A significantly higher proportion of parvalbumin+ inhibitory interneurons express D2Rs than D1Rs. A significantly higher proportion of calbindin+ inhibitory interneurons express D1Rs compared with D2Rs. When pooling across interneuron classes, the proportion of D2R-expressing interneurons is significantly greater than the proportion of D1R-expressing interneurons. We did not perform a statistical comparison between D1R- and D2R-expressing somatostatin+ neurons because they were so rare. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determine using chi-squared tests calculated on total counts (Parvalbumin+ N = 635, P < 10−16; Calbindin+ N = 624, P = 5.7 × 10−5; Calretinin+ N = 648, P = 0.42). Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4; Somatostatin+ D1R, D2R = 3, 4.

    Techniques Used: Expressing

    Distribution of dopamine receptors across inhibitory neuron populations across cortical layers. (A) Across all layers, the proportion of D2R-expressing parvalbumin+ neurons is higher than the proportion of D1R-expressing parvalbumin+ neurons. (B) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calbindin+ neurons across layers. (C) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calretinin+ neurons across layers. Significance was determined using chi-squared tests calculated on total counts. Parvalbumin+ N = 197, 44, 88, 75; P = 1.98 × 10−7, 3.89 × 10−5, 1.36 × 10−10, 4.65 × 10−9 for layers II, III, IV, V, and VI, respectively. Calbindin+ N = 232, 34, 46, 70; P = 0.64, 0.46, 0.61, 0.31 for layers II, III, IV, V, and VI, respectively. Calretinin+ N = 352, 31, 41, 52; P = 5.04 × 10−4, 0.42, 0.87, and 0.27 for layers II, III, IV, V, and VI, respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4.
    Figure Legend Snippet: Distribution of dopamine receptors across inhibitory neuron populations across cortical layers. (A) Across all layers, the proportion of D2R-expressing parvalbumin+ neurons is higher than the proportion of D1R-expressing parvalbumin+ neurons. (B) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calbindin+ neurons across layers. (C) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calretinin+ neurons across layers. Significance was determined using chi-squared tests calculated on total counts. Parvalbumin+ N = 197, 44, 88, 75; P = 1.98 × 10−7, 3.89 × 10−5, 1.36 × 10−10, 4.65 × 10−9 for layers II, III, IV, V, and VI, respectively. Calbindin+ N = 232, 34, 46, 70; P = 0.64, 0.46, 0.61, 0.31 for layers II, III, IV, V, and VI, respectively. Calretinin+ N = 352, 31, 41, 52; P = 5.04 × 10−4, 0.42, 0.87, and 0.27 for layers II, III, IV, V, and VI, respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4.

    Techniques Used: Expressing

    Relative proportion of D1R- and D2R-expressing visual cortex-projecting FEF neurons. The left panel shows the proportion of the 2 populations (V4-projecting and MT-projecting) of neurons that express either D1Rs or D2Rs. The top-right panel shows the proportion of MT-projecting neurons that express either D1Rs or D2Rs. The lower-right panel shows the proportion of V4-projecting FEF neurons that express either D1Rs or D2Rs. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Ns displayed on the bars. Combined P < 10−16, MT-projecting P < 10−16, V4-projecting P = 5 × 10−4. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text (N = 3 for all comparisons).
    Figure Legend Snippet: Relative proportion of D1R- and D2R-expressing visual cortex-projecting FEF neurons. The left panel shows the proportion of the 2 populations (V4-projecting and MT-projecting) of neurons that express either D1Rs or D2Rs. The top-right panel shows the proportion of MT-projecting neurons that express either D1Rs or D2Rs. The lower-right panel shows the proportion of V4-projecting FEF neurons that express either D1Rs or D2Rs. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Ns displayed on the bars. Combined P < 10−16, MT-projecting P < 10−16, V4-projecting P = 5 × 10−4. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text (N = 3 for all comparisons).

    Techniques Used: Expressing

    adr  (Alomone Labs)


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    Alomone Labs adr
    Adr, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    adr - by Bioz Stars, 2023-02
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    d1r  (Alomone Labs)


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    Alomone Labs d1r
    Antibody information
    D1r, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/d1r/product/Alomone Labs
    Average 92 stars, based on 1 article reviews
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    d1r - by Bioz Stars, 2023-02
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    1) Product Images from "Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons"

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    Journal: Cerebral Cortex (New York, NY)

    doi: 10.1093/cercor/bhz078

    Antibody information
    Figure Legend Snippet: Antibody information

    Techniques Used:

    Proportion of neurons expressing dopamine receptors across cortical layers. (A) The density of different neuronal classes across cortical layers. (B) The density of neurons expressing D1Rs or D2Rs for each cortical layer. (C) D1R and D2R expression across FEF cortex. Tissue is from the same animal (Monkey 4) and is oriented with the pial surface at the top and white matter at the bottom. Scale bar = 100 μm.
    Figure Legend Snippet: Proportion of neurons expressing dopamine receptors across cortical layers. (A) The density of different neuronal classes across cortical layers. (B) The density of neurons expressing D1Rs or D2Rs for each cortical layer. (C) D1R and D2R expression across FEF cortex. Tissue is from the same animal (Monkey 4) and is oriented with the pial surface at the top and white matter at the bottom. Scale bar = 100 μm.

    Techniques Used: Expressing

    Proportion of neurogranin+ and SMI-32+ pyramidal neurons that express D1Rs or D2Rs. Significantly more neurogranin+ neurons and SMI-32+ neurons express D1Rs (black) than D2Rs (gray). *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts (Neurogranin+ N = 3028, P < 10−10; SMI32+ N = 225, P = 3.2 × 10−13). Bar heights and standard error bars are calculated from the across-animal mean proportions, and the exact values are described in the main text. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.
    Figure Legend Snippet: Proportion of neurogranin+ and SMI-32+ pyramidal neurons that express D1Rs or D2Rs. Significantly more neurogranin+ neurons and SMI-32+ neurons express D1Rs (black) than D2Rs (gray). *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts (Neurogranin+ N = 3028, P < 10−10; SMI32+ N = 225, P = 3.2 × 10−13). Bar heights and standard error bars are calculated from the across-animal mean proportions, and the exact values are described in the main text. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.

    Techniques Used:

    Distribution of dopamine receptors in pyramidal neuron populations across cortical layers. (A) The proportion of D1R-expressing neurogranin+ pyramidal neurons is larger than the proportion of D2R-expressing neurogranin+ neurons across all layers. This difference was statistically significant in layers II–V. Overall, the ratio of D1Rs to D2Rs decreases across cortical layers (right y-axis). (B) The proportion of D1R-expressing SMI-32+ pyramidal neurons is also larger than the proportion of D2R-expressing SMI-32+ neurons across all layers. This difference was statistically significant in layers II-III, and VI. *, **, and *** denote significance at the level of 0.05, 0.01, and 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Neurogranin+ N = 766, 111, 262, 575; P < 10−16, 0.0048, 9.39 × 10−8, 1.6 × 10−4 for layers II-III, IV, V, and VI, respectively. SMI-32+ N = 72, 31, 35, 73; P = 0.0023, 0.2, 0.09, and 0.0019 for layers II-III, IV, V, and VI respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.
    Figure Legend Snippet: Distribution of dopamine receptors in pyramidal neuron populations across cortical layers. (A) The proportion of D1R-expressing neurogranin+ pyramidal neurons is larger than the proportion of D2R-expressing neurogranin+ neurons across all layers. This difference was statistically significant in layers II–V. Overall, the ratio of D1Rs to D2Rs decreases across cortical layers (right y-axis). (B) The proportion of D1R-expressing SMI-32+ pyramidal neurons is also larger than the proportion of D2R-expressing SMI-32+ neurons across all layers. This difference was statistically significant in layers II-III, and VI. *, **, and *** denote significance at the level of 0.05, 0.01, and 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Neurogranin+ N = 766, 111, 262, 575; P < 10−16, 0.0048, 9.39 × 10−8, 1.6 × 10−4 for layers II-III, IV, V, and VI, respectively. SMI-32+ N = 72, 31, 35, 73; P = 0.0023, 0.2, 0.09, and 0.0019 for layers II-III, IV, V, and VI respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.

    Techniques Used: Expressing

    P -values of layer-versus-layer pairwise comparisons for  D1R  and D2R expression on different neuronal classes
    Figure Legend Snippet: P -values of layer-versus-layer pairwise comparisons for D1R and D2R expression on different neuronal classes

    Techniques Used: Expressing

    Proportion of inhibitory interneuron classes that express D1Rs or D2Rs. A significantly higher proportion of parvalbumin+ inhibitory interneurons express D2Rs than D1Rs. A significantly higher proportion of calbindin+ inhibitory interneurons express D1Rs compared with D2Rs. When pooling across interneuron classes, the proportion of D2R-expressing interneurons is significantly greater than the proportion of D1R-expressing interneurons. We did not perform a statistical comparison between D1R- and D2R-expressing somatostatin+ neurons because they were so rare. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determine using chi-squared tests calculated on total counts (Parvalbumin+ N = 635, P < 10−16; Calbindin+ N = 624, P = 5.7 × 10−5; Calretinin+ N = 648, P = 0.42). Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4; Somatostatin+ D1R, D2R = 3, 4.
    Figure Legend Snippet: Proportion of inhibitory interneuron classes that express D1Rs or D2Rs. A significantly higher proportion of parvalbumin+ inhibitory interneurons express D2Rs than D1Rs. A significantly higher proportion of calbindin+ inhibitory interneurons express D1Rs compared with D2Rs. When pooling across interneuron classes, the proportion of D2R-expressing interneurons is significantly greater than the proportion of D1R-expressing interneurons. We did not perform a statistical comparison between D1R- and D2R-expressing somatostatin+ neurons because they were so rare. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determine using chi-squared tests calculated on total counts (Parvalbumin+ N = 635, P < 10−16; Calbindin+ N = 624, P = 5.7 × 10−5; Calretinin+ N = 648, P = 0.42). Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4; Somatostatin+ D1R, D2R = 3, 4.

    Techniques Used: Expressing

    Distribution of dopamine receptors across inhibitory neuron populations across cortical layers. (A) Across all layers, the proportion of D2R-expressing parvalbumin+ neurons is higher than the proportion of D1R-expressing parvalbumin+ neurons. (B) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calbindin+ neurons across layers. (C) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calretinin+ neurons across layers. Significance was determined using chi-squared tests calculated on total counts. Parvalbumin+ N = 197, 44, 88, 75; P = 1.98 × 10−7, 3.89 × 10−5, 1.36 × 10−10, 4.65 × 10−9 for layers II, III, IV, V, and VI, respectively. Calbindin+ N = 232, 34, 46, 70; P = 0.64, 0.46, 0.61, 0.31 for layers II, III, IV, V, and VI, respectively. Calretinin+ N = 352, 31, 41, 52; P = 5.04 × 10−4, 0.42, 0.87, and 0.27 for layers II, III, IV, V, and VI, respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4.
    Figure Legend Snippet: Distribution of dopamine receptors across inhibitory neuron populations across cortical layers. (A) Across all layers, the proportion of D2R-expressing parvalbumin+ neurons is higher than the proportion of D1R-expressing parvalbumin+ neurons. (B) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calbindin+ neurons across layers. (C) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calretinin+ neurons across layers. Significance was determined using chi-squared tests calculated on total counts. Parvalbumin+ N = 197, 44, 88, 75; P = 1.98 × 10−7, 3.89 × 10−5, 1.36 × 10−10, 4.65 × 10−9 for layers II, III, IV, V, and VI, respectively. Calbindin+ N = 232, 34, 46, 70; P = 0.64, 0.46, 0.61, 0.31 for layers II, III, IV, V, and VI, respectively. Calretinin+ N = 352, 31, 41, 52; P = 5.04 × 10−4, 0.42, 0.87, and 0.27 for layers II, III, IV, V, and VI, respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4.

    Techniques Used: Expressing

    Relative proportion of D1R- and D2R-expressing visual cortex-projecting FEF neurons. The left panel shows the proportion of the 2 populations (V4-projecting and MT-projecting) of neurons that express either D1Rs or D2Rs. The top-right panel shows the proportion of MT-projecting neurons that express either D1Rs or D2Rs. The lower-right panel shows the proportion of V4-projecting FEF neurons that express either D1Rs or D2Rs. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Ns displayed on the bars. Combined P < 10−16, MT-projecting P < 10−16, V4-projecting P = 5 × 10−4. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text (N = 3 for all comparisons).
    Figure Legend Snippet: Relative proportion of D1R- and D2R-expressing visual cortex-projecting FEF neurons. The left panel shows the proportion of the 2 populations (V4-projecting and MT-projecting) of neurons that express either D1Rs or D2Rs. The top-right panel shows the proportion of MT-projecting neurons that express either D1Rs or D2Rs. The lower-right panel shows the proportion of V4-projecting FEF neurons that express either D1Rs or D2Rs. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Ns displayed on the bars. Combined P < 10−16, MT-projecting P < 10−16, V4-projecting P = 5 × 10−4. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text (N = 3 for all comparisons).

    Techniques Used: Expressing

    d1r rabbit polyclonal adr  (Alomone Labs)


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    Alomone Labs d1r rabbit polyclonal adr
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    D1r Rabbit Polyclonal Adr, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    1) Product Images from "Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons"

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    Journal: Cerebral Cortex (New York, NY)

    doi: 10.1093/cercor/bhz078

    Antibody information
    Figure Legend Snippet: Antibody information

    Techniques Used:

    Proportion of neurons expressing dopamine receptors across cortical layers. (A) The density of different neuronal classes across cortical layers. (B) The density of neurons expressing D1Rs or D2Rs for each cortical layer. (C) D1R and D2R expression across FEF cortex. Tissue is from the same animal (Monkey 4) and is oriented with the pial surface at the top and white matter at the bottom. Scale bar = 100 μm.
    Figure Legend Snippet: Proportion of neurons expressing dopamine receptors across cortical layers. (A) The density of different neuronal classes across cortical layers. (B) The density of neurons expressing D1Rs or D2Rs for each cortical layer. (C) D1R and D2R expression across FEF cortex. Tissue is from the same animal (Monkey 4) and is oriented with the pial surface at the top and white matter at the bottom. Scale bar = 100 μm.

    Techniques Used: Expressing

    Proportion of neurogranin+ and SMI-32+ pyramidal neurons that express D1Rs or D2Rs. Significantly more neurogranin+ neurons and SMI-32+ neurons express D1Rs (black) than D2Rs (gray). *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts (Neurogranin+ N = 3028, P < 10−10; SMI32+ N = 225, P = 3.2 × 10−13). Bar heights and standard error bars are calculated from the across-animal mean proportions, and the exact values are described in the main text. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.
    Figure Legend Snippet: Proportion of neurogranin+ and SMI-32+ pyramidal neurons that express D1Rs or D2Rs. Significantly more neurogranin+ neurons and SMI-32+ neurons express D1Rs (black) than D2Rs (gray). *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts (Neurogranin+ N = 3028, P < 10−10; SMI32+ N = 225, P = 3.2 × 10−13). Bar heights and standard error bars are calculated from the across-animal mean proportions, and the exact values are described in the main text. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.

    Techniques Used:

    Distribution of dopamine receptors in pyramidal neuron populations across cortical layers. (A) The proportion of D1R-expressing neurogranin+ pyramidal neurons is larger than the proportion of D2R-expressing neurogranin+ neurons across all layers. This difference was statistically significant in layers II–V. Overall, the ratio of D1Rs to D2Rs decreases across cortical layers (right y-axis). (B) The proportion of D1R-expressing SMI-32+ pyramidal neurons is also larger than the proportion of D2R-expressing SMI-32+ neurons across all layers. This difference was statistically significant in layers II-III, and VI. *, **, and *** denote significance at the level of 0.05, 0.01, and 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Neurogranin+ N = 766, 111, 262, 575; P < 10−16, 0.0048, 9.39 × 10−8, 1.6 × 10−4 for layers II-III, IV, V, and VI, respectively. SMI-32+ N = 72, 31, 35, 73; P = 0.0023, 0.2, 0.09, and 0.0019 for layers II-III, IV, V, and VI respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.
    Figure Legend Snippet: Distribution of dopamine receptors in pyramidal neuron populations across cortical layers. (A) The proportion of D1R-expressing neurogranin+ pyramidal neurons is larger than the proportion of D2R-expressing neurogranin+ neurons across all layers. This difference was statistically significant in layers II–V. Overall, the ratio of D1Rs to D2Rs decreases across cortical layers (right y-axis). (B) The proportion of D1R-expressing SMI-32+ pyramidal neurons is also larger than the proportion of D2R-expressing SMI-32+ neurons across all layers. This difference was statistically significant in layers II-III, and VI. *, **, and *** denote significance at the level of 0.05, 0.01, and 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Neurogranin+ N = 766, 111, 262, 575; P < 10−16, 0.0048, 9.39 × 10−8, 1.6 × 10−4 for layers II-III, IV, V, and VI, respectively. SMI-32+ N = 72, 31, 35, 73; P = 0.0023, 0.2, 0.09, and 0.0019 for layers II-III, IV, V, and VI respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.

    Techniques Used: Expressing

    P -values of layer-versus-layer pairwise comparisons for  D1R  and D2R expression on different neuronal classes
    Figure Legend Snippet: P -values of layer-versus-layer pairwise comparisons for D1R and D2R expression on different neuronal classes

    Techniques Used: Expressing

    Proportion of inhibitory interneuron classes that express D1Rs or D2Rs. A significantly higher proportion of parvalbumin+ inhibitory interneurons express D2Rs than D1Rs. A significantly higher proportion of calbindin+ inhibitory interneurons express D1Rs compared with D2Rs. When pooling across interneuron classes, the proportion of D2R-expressing interneurons is significantly greater than the proportion of D1R-expressing interneurons. We did not perform a statistical comparison between D1R- and D2R-expressing somatostatin+ neurons because they were so rare. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determine using chi-squared tests calculated on total counts (Parvalbumin+ N = 635, P < 10−16; Calbindin+ N = 624, P = 5.7 × 10−5; Calretinin+ N = 648, P = 0.42). Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4; Somatostatin+ D1R, D2R = 3, 4.
    Figure Legend Snippet: Proportion of inhibitory interneuron classes that express D1Rs or D2Rs. A significantly higher proportion of parvalbumin+ inhibitory interneurons express D2Rs than D1Rs. A significantly higher proportion of calbindin+ inhibitory interneurons express D1Rs compared with D2Rs. When pooling across interneuron classes, the proportion of D2R-expressing interneurons is significantly greater than the proportion of D1R-expressing interneurons. We did not perform a statistical comparison between D1R- and D2R-expressing somatostatin+ neurons because they were so rare. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determine using chi-squared tests calculated on total counts (Parvalbumin+ N = 635, P < 10−16; Calbindin+ N = 624, P = 5.7 × 10−5; Calretinin+ N = 648, P = 0.42). Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4; Somatostatin+ D1R, D2R = 3, 4.

    Techniques Used: Expressing

    Distribution of dopamine receptors across inhibitory neuron populations across cortical layers. (A) Across all layers, the proportion of D2R-expressing parvalbumin+ neurons is higher than the proportion of D1R-expressing parvalbumin+ neurons. (B) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calbindin+ neurons across layers. (C) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calretinin+ neurons across layers. Significance was determined using chi-squared tests calculated on total counts. Parvalbumin+ N = 197, 44, 88, 75; P = 1.98 × 10−7, 3.89 × 10−5, 1.36 × 10−10, 4.65 × 10−9 for layers II, III, IV, V, and VI, respectively. Calbindin+ N = 232, 34, 46, 70; P = 0.64, 0.46, 0.61, 0.31 for layers II, III, IV, V, and VI, respectively. Calretinin+ N = 352, 31, 41, 52; P = 5.04 × 10−4, 0.42, 0.87, and 0.27 for layers II, III, IV, V, and VI, respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4.
    Figure Legend Snippet: Distribution of dopamine receptors across inhibitory neuron populations across cortical layers. (A) Across all layers, the proportion of D2R-expressing parvalbumin+ neurons is higher than the proportion of D1R-expressing parvalbumin+ neurons. (B) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calbindin+ neurons across layers. (C) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calretinin+ neurons across layers. Significance was determined using chi-squared tests calculated on total counts. Parvalbumin+ N = 197, 44, 88, 75; P = 1.98 × 10−7, 3.89 × 10−5, 1.36 × 10−10, 4.65 × 10−9 for layers II, III, IV, V, and VI, respectively. Calbindin+ N = 232, 34, 46, 70; P = 0.64, 0.46, 0.61, 0.31 for layers II, III, IV, V, and VI, respectively. Calretinin+ N = 352, 31, 41, 52; P = 5.04 × 10−4, 0.42, 0.87, and 0.27 for layers II, III, IV, V, and VI, respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4.

    Techniques Used: Expressing

    Relative proportion of D1R- and D2R-expressing visual cortex-projecting FEF neurons. The left panel shows the proportion of the 2 populations (V4-projecting and MT-projecting) of neurons that express either D1Rs or D2Rs. The top-right panel shows the proportion of MT-projecting neurons that express either D1Rs or D2Rs. The lower-right panel shows the proportion of V4-projecting FEF neurons that express either D1Rs or D2Rs. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Ns displayed on the bars. Combined P < 10−16, MT-projecting P < 10−16, V4-projecting P = 5 × 10−4. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text (N = 3 for all comparisons).
    Figure Legend Snippet: Relative proportion of D1R- and D2R-expressing visual cortex-projecting FEF neurons. The left panel shows the proportion of the 2 populations (V4-projecting and MT-projecting) of neurons that express either D1Rs or D2Rs. The top-right panel shows the proportion of MT-projecting neurons that express either D1Rs or D2Rs. The lower-right panel shows the proportion of V4-projecting FEF neurons that express either D1Rs or D2Rs. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Ns displayed on the bars. Combined P < 10−16, MT-projecting P < 10−16, V4-projecting P = 5 × 10−4. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text (N = 3 for all comparisons).

    Techniques Used: Expressing

    anti d1r  (Alomone Labs)


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    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: Antibody information

    Article Snippet: DAPI stains DNA and is therefore a label for all nucleated cells. table ft1 table-wrap mode="anchored" t5 Table 3 caption a7 Antigen Host Vendor information Dilution D1R Rabbit polyclonal ADR-001; Alomone Labs, Jerusalem, Israel 1:200 D2R Goat polyclonal SC-7522; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 D2R Rabbit polyclonal ADR-002; Alomone Labs, Jerusalem, Israel 1:200 Neurogranin Mouse monoclonal SC-514922; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 SMI-32 Mouse monoclonal NE1023; Millipore, Temecula, CA 1:1000 Parvalbumin Mouse monoclonal P3088; Sigma-Aldrich Inc., St. Lous, MO 1:1000 Calbindin Mouse monoclonal CB300; Swant Inc., Switzerland 1:1000 Calretinin Mouse monoclonal 6B3; Swant Inc., Switzerland 1:1000 Somatostatin Rat monoclonal MAB354; Millipore, Temecula, CA 1:400 Open in a separate window Antibody information

    Techniques:

    Proportion of neurons expressing dopamine receptors across cortical layers. (A) The density of different neuronal classes across cortical layers. (B) The density of neurons expressing D1Rs or D2Rs for each cortical layer. (C) D1R and D2R expression across FEF cortex. Tissue is from the same animal (Monkey 4) and is oriented with the pial surface at the top and white matter at the bottom. Scale bar = 100 μm.

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: Proportion of neurons expressing dopamine receptors across cortical layers. (A) The density of different neuronal classes across cortical layers. (B) The density of neurons expressing D1Rs or D2Rs for each cortical layer. (C) D1R and D2R expression across FEF cortex. Tissue is from the same animal (Monkey 4) and is oriented with the pial surface at the top and white matter at the bottom. Scale bar = 100 μm.

    Article Snippet: DAPI stains DNA and is therefore a label for all nucleated cells. table ft1 table-wrap mode="anchored" t5 Table 3 caption a7 Antigen Host Vendor information Dilution D1R Rabbit polyclonal ADR-001; Alomone Labs, Jerusalem, Israel 1:200 D2R Goat polyclonal SC-7522; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 D2R Rabbit polyclonal ADR-002; Alomone Labs, Jerusalem, Israel 1:200 Neurogranin Mouse monoclonal SC-514922; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 SMI-32 Mouse monoclonal NE1023; Millipore, Temecula, CA 1:1000 Parvalbumin Mouse monoclonal P3088; Sigma-Aldrich Inc., St. Lous, MO 1:1000 Calbindin Mouse monoclonal CB300; Swant Inc., Switzerland 1:1000 Calretinin Mouse monoclonal 6B3; Swant Inc., Switzerland 1:1000 Somatostatin Rat monoclonal MAB354; Millipore, Temecula, CA 1:400 Open in a separate window Antibody information

    Techniques: Expressing

    Proportion of neurogranin+ and SMI-32+ pyramidal neurons that express D1Rs or D2Rs. Significantly more neurogranin+ neurons and SMI-32+ neurons express D1Rs (black) than D2Rs (gray). *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts (Neurogranin+ N = 3028, P < 10−10; SMI32+ N = 225, P = 3.2 × 10−13). Bar heights and standard error bars are calculated from the across-animal mean proportions, and the exact values are described in the main text. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: Proportion of neurogranin+ and SMI-32+ pyramidal neurons that express D1Rs or D2Rs. Significantly more neurogranin+ neurons and SMI-32+ neurons express D1Rs (black) than D2Rs (gray). *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts (Neurogranin+ N = 3028, P < 10−10; SMI32+ N = 225, P = 3.2 × 10−13). Bar heights and standard error bars are calculated from the across-animal mean proportions, and the exact values are described in the main text. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.

    Article Snippet: DAPI stains DNA and is therefore a label for all nucleated cells. table ft1 table-wrap mode="anchored" t5 Table 3 caption a7 Antigen Host Vendor information Dilution D1R Rabbit polyclonal ADR-001; Alomone Labs, Jerusalem, Israel 1:200 D2R Goat polyclonal SC-7522; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 D2R Rabbit polyclonal ADR-002; Alomone Labs, Jerusalem, Israel 1:200 Neurogranin Mouse monoclonal SC-514922; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 SMI-32 Mouse monoclonal NE1023; Millipore, Temecula, CA 1:1000 Parvalbumin Mouse monoclonal P3088; Sigma-Aldrich Inc., St. Lous, MO 1:1000 Calbindin Mouse monoclonal CB300; Swant Inc., Switzerland 1:1000 Calretinin Mouse monoclonal 6B3; Swant Inc., Switzerland 1:1000 Somatostatin Rat monoclonal MAB354; Millipore, Temecula, CA 1:400 Open in a separate window Antibody information

    Techniques:

    Distribution of dopamine receptors in pyramidal neuron populations across cortical layers. (A) The proportion of D1R-expressing neurogranin+ pyramidal neurons is larger than the proportion of D2R-expressing neurogranin+ neurons across all layers. This difference was statistically significant in layers II–V. Overall, the ratio of D1Rs to D2Rs decreases across cortical layers (right y-axis). (B) The proportion of D1R-expressing SMI-32+ pyramidal neurons is also larger than the proportion of D2R-expressing SMI-32+ neurons across all layers. This difference was statistically significant in layers II-III, and VI. *, **, and *** denote significance at the level of 0.05, 0.01, and 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Neurogranin+ N = 766, 111, 262, 575; P < 10−16, 0.0048, 9.39 × 10−8, 1.6 × 10−4 for layers II-III, IV, V, and VI, respectively. SMI-32+ N = 72, 31, 35, 73; P = 0.0023, 0.2, 0.09, and 0.0019 for layers II-III, IV, V, and VI respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: Distribution of dopamine receptors in pyramidal neuron populations across cortical layers. (A) The proportion of D1R-expressing neurogranin+ pyramidal neurons is larger than the proportion of D2R-expressing neurogranin+ neurons across all layers. This difference was statistically significant in layers II–V. Overall, the ratio of D1Rs to D2Rs decreases across cortical layers (right y-axis). (B) The proportion of D1R-expressing SMI-32+ pyramidal neurons is also larger than the proportion of D2R-expressing SMI-32+ neurons across all layers. This difference was statistically significant in layers II-III, and VI. *, **, and *** denote significance at the level of 0.05, 0.01, and 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Neurogranin+ N = 766, 111, 262, 575; P < 10−16, 0.0048, 9.39 × 10−8, 1.6 × 10−4 for layers II-III, IV, V, and VI, respectively. SMI-32+ N = 72, 31, 35, 73; P = 0.0023, 0.2, 0.09, and 0.0019 for layers II-III, IV, V, and VI respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.

    Article Snippet: DAPI stains DNA and is therefore a label for all nucleated cells. table ft1 table-wrap mode="anchored" t5 Table 3 caption a7 Antigen Host Vendor information Dilution D1R Rabbit polyclonal ADR-001; Alomone Labs, Jerusalem, Israel 1:200 D2R Goat polyclonal SC-7522; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 D2R Rabbit polyclonal ADR-002; Alomone Labs, Jerusalem, Israel 1:200 Neurogranin Mouse monoclonal SC-514922; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 SMI-32 Mouse monoclonal NE1023; Millipore, Temecula, CA 1:1000 Parvalbumin Mouse monoclonal P3088; Sigma-Aldrich Inc., St. Lous, MO 1:1000 Calbindin Mouse monoclonal CB300; Swant Inc., Switzerland 1:1000 Calretinin Mouse monoclonal 6B3; Swant Inc., Switzerland 1:1000 Somatostatin Rat monoclonal MAB354; Millipore, Temecula, CA 1:400 Open in a separate window Antibody information

    Techniques: Expressing

    P -values of layer-versus-layer pairwise comparisons for  D1R  and D2R expression on different neuronal classes

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: P -values of layer-versus-layer pairwise comparisons for D1R and D2R expression on different neuronal classes

    Article Snippet: DAPI stains DNA and is therefore a label for all nucleated cells. table ft1 table-wrap mode="anchored" t5 Table 3 caption a7 Antigen Host Vendor information Dilution D1R Rabbit polyclonal ADR-001; Alomone Labs, Jerusalem, Israel 1:200 D2R Goat polyclonal SC-7522; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 D2R Rabbit polyclonal ADR-002; Alomone Labs, Jerusalem, Israel 1:200 Neurogranin Mouse monoclonal SC-514922; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 SMI-32 Mouse monoclonal NE1023; Millipore, Temecula, CA 1:1000 Parvalbumin Mouse monoclonal P3088; Sigma-Aldrich Inc., St. Lous, MO 1:1000 Calbindin Mouse monoclonal CB300; Swant Inc., Switzerland 1:1000 Calretinin Mouse monoclonal 6B3; Swant Inc., Switzerland 1:1000 Somatostatin Rat monoclonal MAB354; Millipore, Temecula, CA 1:400 Open in a separate window Antibody information

    Techniques: Expressing

    Proportion of inhibitory interneuron classes that express D1Rs or D2Rs. A significantly higher proportion of parvalbumin+ inhibitory interneurons express D2Rs than D1Rs. A significantly higher proportion of calbindin+ inhibitory interneurons express D1Rs compared with D2Rs. When pooling across interneuron classes, the proportion of D2R-expressing interneurons is significantly greater than the proportion of D1R-expressing interneurons. We did not perform a statistical comparison between D1R- and D2R-expressing somatostatin+ neurons because they were so rare. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determine using chi-squared tests calculated on total counts (Parvalbumin+ N = 635, P < 10−16; Calbindin+ N = 624, P = 5.7 × 10−5; Calretinin+ N = 648, P = 0.42). Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4; Somatostatin+ D1R, D2R = 3, 4.

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: Proportion of inhibitory interneuron classes that express D1Rs or D2Rs. A significantly higher proportion of parvalbumin+ inhibitory interneurons express D2Rs than D1Rs. A significantly higher proportion of calbindin+ inhibitory interneurons express D1Rs compared with D2Rs. When pooling across interneuron classes, the proportion of D2R-expressing interneurons is significantly greater than the proportion of D1R-expressing interneurons. We did not perform a statistical comparison between D1R- and D2R-expressing somatostatin+ neurons because they were so rare. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determine using chi-squared tests calculated on total counts (Parvalbumin+ N = 635, P < 10−16; Calbindin+ N = 624, P = 5.7 × 10−5; Calretinin+ N = 648, P = 0.42). Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4; Somatostatin+ D1R, D2R = 3, 4.

    Article Snippet: DAPI stains DNA and is therefore a label for all nucleated cells. table ft1 table-wrap mode="anchored" t5 Table 3 caption a7 Antigen Host Vendor information Dilution D1R Rabbit polyclonal ADR-001; Alomone Labs, Jerusalem, Israel 1:200 D2R Goat polyclonal SC-7522; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 D2R Rabbit polyclonal ADR-002; Alomone Labs, Jerusalem, Israel 1:200 Neurogranin Mouse monoclonal SC-514922; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 SMI-32 Mouse monoclonal NE1023; Millipore, Temecula, CA 1:1000 Parvalbumin Mouse monoclonal P3088; Sigma-Aldrich Inc., St. Lous, MO 1:1000 Calbindin Mouse monoclonal CB300; Swant Inc., Switzerland 1:1000 Calretinin Mouse monoclonal 6B3; Swant Inc., Switzerland 1:1000 Somatostatin Rat monoclonal MAB354; Millipore, Temecula, CA 1:400 Open in a separate window Antibody information

    Techniques: Expressing

    Distribution of dopamine receptors across inhibitory neuron populations across cortical layers. (A) Across all layers, the proportion of D2R-expressing parvalbumin+ neurons is higher than the proportion of D1R-expressing parvalbumin+ neurons. (B) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calbindin+ neurons across layers. (C) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calretinin+ neurons across layers. Significance was determined using chi-squared tests calculated on total counts. Parvalbumin+ N = 197, 44, 88, 75; P = 1.98 × 10−7, 3.89 × 10−5, 1.36 × 10−10, 4.65 × 10−9 for layers II, III, IV, V, and VI, respectively. Calbindin+ N = 232, 34, 46, 70; P = 0.64, 0.46, 0.61, 0.31 for layers II, III, IV, V, and VI, respectively. Calretinin+ N = 352, 31, 41, 52; P = 5.04 × 10−4, 0.42, 0.87, and 0.27 for layers II, III, IV, V, and VI, respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4.

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: Distribution of dopamine receptors across inhibitory neuron populations across cortical layers. (A) Across all layers, the proportion of D2R-expressing parvalbumin+ neurons is higher than the proportion of D1R-expressing parvalbumin+ neurons. (B) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calbindin+ neurons across layers. (C) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calretinin+ neurons across layers. Significance was determined using chi-squared tests calculated on total counts. Parvalbumin+ N = 197, 44, 88, 75; P = 1.98 × 10−7, 3.89 × 10−5, 1.36 × 10−10, 4.65 × 10−9 for layers II, III, IV, V, and VI, respectively. Calbindin+ N = 232, 34, 46, 70; P = 0.64, 0.46, 0.61, 0.31 for layers II, III, IV, V, and VI, respectively. Calretinin+ N = 352, 31, 41, 52; P = 5.04 × 10−4, 0.42, 0.87, and 0.27 for layers II, III, IV, V, and VI, respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4.

    Article Snippet: DAPI stains DNA and is therefore a label for all nucleated cells. table ft1 table-wrap mode="anchored" t5 Table 3 caption a7 Antigen Host Vendor information Dilution D1R Rabbit polyclonal ADR-001; Alomone Labs, Jerusalem, Israel 1:200 D2R Goat polyclonal SC-7522; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 D2R Rabbit polyclonal ADR-002; Alomone Labs, Jerusalem, Israel 1:200 Neurogranin Mouse monoclonal SC-514922; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 SMI-32 Mouse monoclonal NE1023; Millipore, Temecula, CA 1:1000 Parvalbumin Mouse monoclonal P3088; Sigma-Aldrich Inc., St. Lous, MO 1:1000 Calbindin Mouse monoclonal CB300; Swant Inc., Switzerland 1:1000 Calretinin Mouse monoclonal 6B3; Swant Inc., Switzerland 1:1000 Somatostatin Rat monoclonal MAB354; Millipore, Temecula, CA 1:400 Open in a separate window Antibody information

    Techniques: Expressing

    Relative proportion of D1R- and D2R-expressing visual cortex-projecting FEF neurons. The left panel shows the proportion of the 2 populations (V4-projecting and MT-projecting) of neurons that express either D1Rs or D2Rs. The top-right panel shows the proportion of MT-projecting neurons that express either D1Rs or D2Rs. The lower-right panel shows the proportion of V4-projecting FEF neurons that express either D1Rs or D2Rs. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Ns displayed on the bars. Combined P < 10−16, MT-projecting P < 10−16, V4-projecting P = 5 × 10−4. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text (N = 3 for all comparisons).

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: Relative proportion of D1R- and D2R-expressing visual cortex-projecting FEF neurons. The left panel shows the proportion of the 2 populations (V4-projecting and MT-projecting) of neurons that express either D1Rs or D2Rs. The top-right panel shows the proportion of MT-projecting neurons that express either D1Rs or D2Rs. The lower-right panel shows the proportion of V4-projecting FEF neurons that express either D1Rs or D2Rs. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Ns displayed on the bars. Combined P < 10−16, MT-projecting P < 10−16, V4-projecting P = 5 × 10−4. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text (N = 3 for all comparisons).

    Article Snippet: DAPI stains DNA and is therefore a label for all nucleated cells. table ft1 table-wrap mode="anchored" t5 Table 3 caption a7 Antigen Host Vendor information Dilution D1R Rabbit polyclonal ADR-001; Alomone Labs, Jerusalem, Israel 1:200 D2R Goat polyclonal SC-7522; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 D2R Rabbit polyclonal ADR-002; Alomone Labs, Jerusalem, Israel 1:200 Neurogranin Mouse monoclonal SC-514922; Santa Cruz Biotechnology, Santa Cruz, CA 1:200 SMI-32 Mouse monoclonal NE1023; Millipore, Temecula, CA 1:1000 Parvalbumin Mouse monoclonal P3088; Sigma-Aldrich Inc., St. Lous, MO 1:1000 Calbindin Mouse monoclonal CB300; Swant Inc., Switzerland 1:1000 Calretinin Mouse monoclonal 6B3; Swant Inc., Switzerland 1:1000 Somatostatin Rat monoclonal MAB354; Millipore, Temecula, CA 1:400 Open in a separate window Antibody information

    Techniques: Expressing

    Antibody information

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: Antibody information

    Article Snippet: D1R , Rabbit polyclonal , ADR-001; Alomone Labs, Jerusalem, Israel , 1:200.

    Techniques:

    Proportion of neurons expressing dopamine receptors across cortical layers. (A) The density of different neuronal classes across cortical layers. (B) The density of neurons expressing D1Rs or D2Rs for each cortical layer. (C) D1R and D2R expression across FEF cortex. Tissue is from the same animal (Monkey 4) and is oriented with the pial surface at the top and white matter at the bottom. Scale bar = 100 μm.

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: Proportion of neurons expressing dopamine receptors across cortical layers. (A) The density of different neuronal classes across cortical layers. (B) The density of neurons expressing D1Rs or D2Rs for each cortical layer. (C) D1R and D2R expression across FEF cortex. Tissue is from the same animal (Monkey 4) and is oriented with the pial surface at the top and white matter at the bottom. Scale bar = 100 μm.

    Article Snippet: D1R , Rabbit polyclonal , ADR-001; Alomone Labs, Jerusalem, Israel , 1:200.

    Techniques: Expressing

    Proportion of neurogranin+ and SMI-32+ pyramidal neurons that express D1Rs or D2Rs. Significantly more neurogranin+ neurons and SMI-32+ neurons express D1Rs (black) than D2Rs (gray). *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts (Neurogranin+ N = 3028, P < 10−10; SMI32+ N = 225, P = 3.2 × 10−13). Bar heights and standard error bars are calculated from the across-animal mean proportions, and the exact values are described in the main text. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: Proportion of neurogranin+ and SMI-32+ pyramidal neurons that express D1Rs or D2Rs. Significantly more neurogranin+ neurons and SMI-32+ neurons express D1Rs (black) than D2Rs (gray). *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts (Neurogranin+ N = 3028, P < 10−10; SMI32+ N = 225, P = 3.2 × 10−13). Bar heights and standard error bars are calculated from the across-animal mean proportions, and the exact values are described in the main text. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.

    Article Snippet: D1R , Rabbit polyclonal , ADR-001; Alomone Labs, Jerusalem, Israel , 1:200.

    Techniques:

    Distribution of dopamine receptors in pyramidal neuron populations across cortical layers. (A) The proportion of D1R-expressing neurogranin+ pyramidal neurons is larger than the proportion of D2R-expressing neurogranin+ neurons across all layers. This difference was statistically significant in layers II–V. Overall, the ratio of D1Rs to D2Rs decreases across cortical layers (right y-axis). (B) The proportion of D1R-expressing SMI-32+ pyramidal neurons is also larger than the proportion of D2R-expressing SMI-32+ neurons across all layers. This difference was statistically significant in layers II-III, and VI. *, **, and *** denote significance at the level of 0.05, 0.01, and 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Neurogranin+ N = 766, 111, 262, 575; P < 10−16, 0.0048, 9.39 × 10−8, 1.6 × 10−4 for layers II-III, IV, V, and VI, respectively. SMI-32+ N = 72, 31, 35, 73; P = 0.0023, 0.2, 0.09, and 0.0019 for layers II-III, IV, V, and VI respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: Distribution of dopamine receptors in pyramidal neuron populations across cortical layers. (A) The proportion of D1R-expressing neurogranin+ pyramidal neurons is larger than the proportion of D2R-expressing neurogranin+ neurons across all layers. This difference was statistically significant in layers II–V. Overall, the ratio of D1Rs to D2Rs decreases across cortical layers (right y-axis). (B) The proportion of D1R-expressing SMI-32+ pyramidal neurons is also larger than the proportion of D2R-expressing SMI-32+ neurons across all layers. This difference was statistically significant in layers II-III, and VI. *, **, and *** denote significance at the level of 0.05, 0.01, and 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Neurogranin+ N = 766, 111, 262, 575; P < 10−16, 0.0048, 9.39 × 10−8, 1.6 × 10−4 for layers II-III, IV, V, and VI, respectively. SMI-32+ N = 72, 31, 35, 73; P = 0.0023, 0.2, 0.09, and 0.0019 for layers II-III, IV, V, and VI respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Neurogranin+ D1R, D2R = 4, 4; SMI-32+ D1R, D2R = 3, 4.

    Article Snippet: D1R , Rabbit polyclonal , ADR-001; Alomone Labs, Jerusalem, Israel , 1:200.

    Techniques: Expressing

    P -values of layer-versus-layer pairwise comparisons for  D1R  and D2R expression on different neuronal classes

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: P -values of layer-versus-layer pairwise comparisons for D1R and D2R expression on different neuronal classes

    Article Snippet: D1R , Rabbit polyclonal , ADR-001; Alomone Labs, Jerusalem, Israel , 1:200.

    Techniques: Expressing

    Proportion of inhibitory interneuron classes that express D1Rs or D2Rs. A significantly higher proportion of parvalbumin+ inhibitory interneurons express D2Rs than D1Rs. A significantly higher proportion of calbindin+ inhibitory interneurons express D1Rs compared with D2Rs. When pooling across interneuron classes, the proportion of D2R-expressing interneurons is significantly greater than the proportion of D1R-expressing interneurons. We did not perform a statistical comparison between D1R- and D2R-expressing somatostatin+ neurons because they were so rare. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determine using chi-squared tests calculated on total counts (Parvalbumin+ N = 635, P < 10−16; Calbindin+ N = 624, P = 5.7 × 10−5; Calretinin+ N = 648, P = 0.42). Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4; Somatostatin+ D1R, D2R = 3, 4.

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: Proportion of inhibitory interneuron classes that express D1Rs or D2Rs. A significantly higher proportion of parvalbumin+ inhibitory interneurons express D2Rs than D1Rs. A significantly higher proportion of calbindin+ inhibitory interneurons express D1Rs compared with D2Rs. When pooling across interneuron classes, the proportion of D2R-expressing interneurons is significantly greater than the proportion of D1R-expressing interneurons. We did not perform a statistical comparison between D1R- and D2R-expressing somatostatin+ neurons because they were so rare. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determine using chi-squared tests calculated on total counts (Parvalbumin+ N = 635, P < 10−16; Calbindin+ N = 624, P = 5.7 × 10−5; Calretinin+ N = 648, P = 0.42). Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4; Somatostatin+ D1R, D2R = 3, 4.

    Article Snippet: D1R , Rabbit polyclonal , ADR-001; Alomone Labs, Jerusalem, Israel , 1:200.

    Techniques: Expressing

    Distribution of dopamine receptors across inhibitory neuron populations across cortical layers. (A) Across all layers, the proportion of D2R-expressing parvalbumin+ neurons is higher than the proportion of D1R-expressing parvalbumin+ neurons. (B) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calbindin+ neurons across layers. (C) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calretinin+ neurons across layers. Significance was determined using chi-squared tests calculated on total counts. Parvalbumin+ N = 197, 44, 88, 75; P = 1.98 × 10−7, 3.89 × 10−5, 1.36 × 10−10, 4.65 × 10−9 for layers II, III, IV, V, and VI, respectively. Calbindin+ N = 232, 34, 46, 70; P = 0.64, 0.46, 0.61, 0.31 for layers II, III, IV, V, and VI, respectively. Calretinin+ N = 352, 31, 41, 52; P = 5.04 × 10−4, 0.42, 0.87, and 0.27 for layers II, III, IV, V, and VI, respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4.

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: Distribution of dopamine receptors across inhibitory neuron populations across cortical layers. (A) Across all layers, the proportion of D2R-expressing parvalbumin+ neurons is higher than the proportion of D1R-expressing parvalbumin+ neurons. (B) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calbindin+ neurons across layers. (C) There is no significant difference in the relative prevalence of D1Rs compared with D2Rs in calretinin+ neurons across layers. Significance was determined using chi-squared tests calculated on total counts. Parvalbumin+ N = 197, 44, 88, 75; P = 1.98 × 10−7, 3.89 × 10−5, 1.36 × 10−10, 4.65 × 10−9 for layers II, III, IV, V, and VI, respectively. Calbindin+ N = 232, 34, 46, 70; P = 0.64, 0.46, 0.61, 0.31 for layers II, III, IV, V, and VI, respectively. Calretinin+ N = 352, 31, 41, 52; P = 5.04 × 10−4, 0.42, 0.87, and 0.27 for layers II, III, IV, V, and VI, respectively. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in Table ​Table4.4. Animal Ns respectively for Parvalbumin+ D1R, D2R = 4, 3; Calbindin+ D1R, D2R = 4, 4; Calretinin+ D1R, D2R = 3, 4.

    Article Snippet: D1R , Rabbit polyclonal , ADR-001; Alomone Labs, Jerusalem, Israel , 1:200.

    Techniques: Expressing

    Relative proportion of D1R- and D2R-expressing visual cortex-projecting FEF neurons. The left panel shows the proportion of the 2 populations (V4-projecting and MT-projecting) of neurons that express either D1Rs or D2Rs. The top-right panel shows the proportion of MT-projecting neurons that express either D1Rs or D2Rs. The lower-right panel shows the proportion of V4-projecting FEF neurons that express either D1Rs or D2Rs. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Ns displayed on the bars. Combined P < 10−16, MT-projecting P < 10−16, V4-projecting P = 5 × 10−4. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text (N = 3 for all comparisons).

    Journal: Cerebral Cortex (New York, NY)

    Article Title: Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons

    doi: 10.1093/cercor/bhz078

    Figure Lengend Snippet: Relative proportion of D1R- and D2R-expressing visual cortex-projecting FEF neurons. The left panel shows the proportion of the 2 populations (V4-projecting and MT-projecting) of neurons that express either D1Rs or D2Rs. The top-right panel shows the proportion of MT-projecting neurons that express either D1Rs or D2Rs. The lower-right panel shows the proportion of V4-projecting FEF neurons that express either D1Rs or D2Rs. *** denotes significance at the level of 0.001 after Bonferroni correction. Significance was determined using chi-squared tests calculated on total counts. Ns displayed on the bars. Combined P < 10−16, MT-projecting P < 10−16, V4-projecting P = 5 × 10−4. Bar heights and standard error bars are calculated from the across-animal mean proportions and the exact values are described in the main text (N = 3 for all comparisons).

    Article Snippet: D1R , Rabbit polyclonal , ADR-001; Alomone Labs, Jerusalem, Israel , 1:200.

    Techniques: Expressing