anti perlecan a7l6 antibody (Novus Biologicals)
Anti Perlecan A7l6 Antibody, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti perlecan a7l6 antibody/product/Novus Biologicals
Average 91 stars, based on 1 article reviews
Price from $9.99 to $1999.99
1) Product Images from "Trabecular Bone Deficit and Enhanced Anabolic Response to Re-Ambulation after Disuse in Perlecan-Deficient Skeleton"
Article Title: Trabecular Bone Deficit and Enhanced Anabolic Response to Re-Ambulation after Disuse in Perlecan-Deficient Skeleton
Figure Legend Snippet: Severe trabecular osteoporosis in perlecan-deficient (Hypo) male skeletons. Distal femur (long bone) was examined ( A ) in various age groups by ex vivo μCT imaging and ( B ) in a longitudinal study using in vivo μCT imaging. ( C ) Histomorphometric and histological analysis of osteoblastic bone formation indices and osteoclastic TRAP staining. The axial skeleton (spinal column and/or the vertebral body L4) was examined ( D ) in various age groups by ex vivo μCT imaging ( E ) and in a longitudinal study by in vivo μCT imaging. Significance for within-genotype age comparisons is indicated by different letters (uppercase for WT and lowercase for Hypo) and between-genotype comparisons are indicated by * p < 0.05). Scale bar in D = 1 mm.
Techniques Used: Ex Vivo, Imaging, In Vivo, Staining
Figure Legend Snippet: Perlecan deficiency altered MSC differentiation, but not proliferation ( A ), and increased osteoclastogenesis and resorptive activity ( B ). Perlecan content was reduced in Hypo marrow ( C ). Treating the primary MSC and osteoclast progenitor cells with exogenous heparin rescued the effects from the perlecan deficiency ( D ). Significance for within-genotype dose comparisons are indicated by different letters (uppercase for WT and lowercase for Hypo) and between-genotype comparisons indicated by * ( p < 0.05). Open bars: WT; filled bars: Hypo.
Techniques Used: Activity Assay