anti p2x7r 1 50  (Alomone Labs)


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    Alomone Labs anti p2x7r 1 50
    Anti P2x7r 1 50, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti p2x7r 1 50/product/Alomone Labs
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti p2x7r 1 50 - by Bioz Stars, 2022-08
    90/100 stars

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    Alomone Labs primary antibodies for p2x7r
    Effect of <t>P2X7R</t> inhibitor on diabetic renal macrophage accrual. Interstitial macrophage abundance (a). Renal interstitial CD68 staining, indicated by black arrows, in sham-treated rat kidney with minimal macrophage staining (b), UNx STZ Drug vehicle-treated diabetic rat kidney with interstitial macrophage accumulation (c), Unx STZ rat treated with 10 mg/kg P2X7Ri (d), and 50 mg/kg P2X7Ri-treated rat kidney (e). Glomerular macrophage abundance (f). Measurements were made at 12 weeks. *P
    Primary Antibodies For P2x7r, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primary antibodies for p2x7r/product/Alomone Labs
    Average 95 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    primary antibodies for p2x7r - by Bioz Stars, 2022-08
    95/100 stars
      Buy from Supplier

    90
    Alomone Labs anti p2x7r 1 50
    Effect of <t>P2X7R</t> inhibitor on diabetic renal macrophage accrual. Interstitial macrophage abundance (a). Renal interstitial CD68 staining, indicated by black arrows, in sham-treated rat kidney with minimal macrophage staining (b), UNx STZ Drug vehicle-treated diabetic rat kidney with interstitial macrophage accumulation (c), Unx STZ rat treated with 10 mg/kg P2X7Ri (d), and 50 mg/kg P2X7Ri-treated rat kidney (e). Glomerular macrophage abundance (f). Measurements were made at 12 weeks. *P
    Anti P2x7r 1 50, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti p2x7r 1 50/product/Alomone Labs
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti p2x7r 1 50 - by Bioz Stars, 2022-08
    90/100 stars
      Buy from Supplier

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    Effect of P2X7R inhibitor on diabetic renal macrophage accrual. Interstitial macrophage abundance (a). Renal interstitial CD68 staining, indicated by black arrows, in sham-treated rat kidney with minimal macrophage staining (b), UNx STZ Drug vehicle-treated diabetic rat kidney with interstitial macrophage accumulation (c), Unx STZ rat treated with 10 mg/kg P2X7Ri (d), and 50 mg/kg P2X7Ri-treated rat kidney (e). Glomerular macrophage abundance (f). Measurements were made at 12 weeks. *P

    Journal: EBioMedicine

    Article Title: Hyperglycemia-induced Renal P2X7 Receptor Activation Enhances Diabetes-related Injury

    doi: 10.1016/j.ebiom.2017.04.011

    Figure Lengend Snippet: Effect of P2X7R inhibitor on diabetic renal macrophage accrual. Interstitial macrophage abundance (a). Renal interstitial CD68 staining, indicated by black arrows, in sham-treated rat kidney with minimal macrophage staining (b), UNx STZ Drug vehicle-treated diabetic rat kidney with interstitial macrophage accumulation (c), Unx STZ rat treated with 10 mg/kg P2X7Ri (d), and 50 mg/kg P2X7Ri-treated rat kidney (e). Glomerular macrophage abundance (f). Measurements were made at 12 weeks. *P

    Article Snippet: Primary antibodies for P2X7R (APR-004, Alomone, RRID: AB_2040068 ; 1:50 murine; 1:100 human), human CD68 (Clone KP-1, Dako, RRID: AB_563621 ; 1:100), murine CD68 (Clone FA-11, Serotec, RRID: AB_323909 ; 1:200) and collagen IV (Ab6586, Abcam, RRID: AB_305584; 1:100) were reconstituted in PBS.

    Techniques: Staining

    Immunolocalization of P2X7R in rat kidney. Normal Wistar Han kidney collected during UNx (a). Kidney tissue from a week 12 vehicle-injected UNx Wistar Han rat (b). Representative P2X7R staining in a UNx STZ Veh rat kidney at week 12 (c). P2X7R staining in and STZ injected UNx rat where anti-P2X7 antibody was pre-absorbed with its conjugate peptide (1:1) to demonstrate antibody specificity (d). a–d × 200 mag.

    Journal: EBioMedicine

    Article Title: Hyperglycemia-induced Renal P2X7 Receptor Activation Enhances Diabetes-related Injury

    doi: 10.1016/j.ebiom.2017.04.011

    Figure Lengend Snippet: Immunolocalization of P2X7R in rat kidney. Normal Wistar Han kidney collected during UNx (a). Kidney tissue from a week 12 vehicle-injected UNx Wistar Han rat (b). Representative P2X7R staining in a UNx STZ Veh rat kidney at week 12 (c). P2X7R staining in and STZ injected UNx rat where anti-P2X7 antibody was pre-absorbed with its conjugate peptide (1:1) to demonstrate antibody specificity (d). a–d × 200 mag.

    Article Snippet: Primary antibodies for P2X7R (APR-004, Alomone, RRID: AB_2040068 ; 1:50 murine; 1:100 human), human CD68 (Clone KP-1, Dako, RRID: AB_563621 ; 1:100), murine CD68 (Clone FA-11, Serotec, RRID: AB_323909 ; 1:200) and collagen IV (Ab6586, Abcam, RRID: AB_305584; 1:100) were reconstituted in PBS.

    Techniques: Injection, Staining

    Renal P2X7R in human diabetic nephropathy. Patient biopsies expressing (a) P2X7R protein and (b) CD68 + monocytes in glomeruli indicated with black arrows. In the most severe cases (c) P2X7R staining and (d) CD68 + staining of the interstitium overlapped in regions of inflammation. Estimated glomerular filtration rate (eGFR) (e), fibrosis (f) and mesangial expansion (g) in patients with interstitial (DNInt = 7), glomerular (DNGlom = 5) P2X7R immunoreactivity compared to thin basement membrane (TBM = 3) controls subjects. *P

    Journal: EBioMedicine

    Article Title: Hyperglycemia-induced Renal P2X7 Receptor Activation Enhances Diabetes-related Injury

    doi: 10.1016/j.ebiom.2017.04.011

    Figure Lengend Snippet: Renal P2X7R in human diabetic nephropathy. Patient biopsies expressing (a) P2X7R protein and (b) CD68 + monocytes in glomeruli indicated with black arrows. In the most severe cases (c) P2X7R staining and (d) CD68 + staining of the interstitium overlapped in regions of inflammation. Estimated glomerular filtration rate (eGFR) (e), fibrosis (f) and mesangial expansion (g) in patients with interstitial (DNInt = 7), glomerular (DNGlom = 5) P2X7R immunoreactivity compared to thin basement membrane (TBM = 3) controls subjects. *P

    Article Snippet: Primary antibodies for P2X7R (APR-004, Alomone, RRID: AB_2040068 ; 1:50 murine; 1:100 human), human CD68 (Clone KP-1, Dako, RRID: AB_563621 ; 1:100), murine CD68 (Clone FA-11, Serotec, RRID: AB_323909 ; 1:200) and collagen IV (Ab6586, Abcam, RRID: AB_305584; 1:100) were reconstituted in PBS.

    Techniques: Expressing, Staining, Filtration

    P2X7R-deficient mice and STZ-induced glomerular macrophage accrual. Change in blood glucose following STZ injections (a). Renal P2X7 mRNA levels (b). Glomerular P2X7R staining in WT (bi) and P2X7R-deficient mice (bii). Glomerular macrophage accumulation following STZ (c). Glomerular CD68 staining in WT (ci) and P2X7R-deficient mice (cii). Glomerular type IV collagen deposition increased following STZ (d). Immunolocalization of lomerular collagen IV staining in WT (di) and P2X7R-deficient mice (dii). *P

    Journal: EBioMedicine

    Article Title: Hyperglycemia-induced Renal P2X7 Receptor Activation Enhances Diabetes-related Injury

    doi: 10.1016/j.ebiom.2017.04.011

    Figure Lengend Snippet: P2X7R-deficient mice and STZ-induced glomerular macrophage accrual. Change in blood glucose following STZ injections (a). Renal P2X7 mRNA levels (b). Glomerular P2X7R staining in WT (bi) and P2X7R-deficient mice (bii). Glomerular macrophage accumulation following STZ (c). Glomerular CD68 staining in WT (ci) and P2X7R-deficient mice (cii). Glomerular type IV collagen deposition increased following STZ (d). Immunolocalization of lomerular collagen IV staining in WT (di) and P2X7R-deficient mice (dii). *P

    Article Snippet: Primary antibodies for P2X7R (APR-004, Alomone, RRID: AB_2040068 ; 1:50 murine; 1:100 human), human CD68 (Clone KP-1, Dako, RRID: AB_563621 ; 1:100), murine CD68 (Clone FA-11, Serotec, RRID: AB_323909 ; 1:200) and collagen IV (Ab6586, Abcam, RRID: AB_305584; 1:100) were reconstituted in PBS.

    Techniques: Mouse Assay, Staining

    Glomerular mesangial P2X7R and MCP-1. Activation of P2X7R with BzATP increased MCP-1 secretion from pHMCs under high glucose conditions (a). P2X7R protein expression in mesangial cells under normal and high glucose conditions (b). Effect of a P2X7R inhibitor (A438079) on MCP-1 secretion (c). Subtraction of normal glucose MCP-1 release highlighted the absolute magnitude of MCP-1 reduction by P2X7R blockade alone across 9 separate experiments (d). *P

    Journal: EBioMedicine

    Article Title: Hyperglycemia-induced Renal P2X7 Receptor Activation Enhances Diabetes-related Injury

    doi: 10.1016/j.ebiom.2017.04.011

    Figure Lengend Snippet: Glomerular mesangial P2X7R and MCP-1. Activation of P2X7R with BzATP increased MCP-1 secretion from pHMCs under high glucose conditions (a). P2X7R protein expression in mesangial cells under normal and high glucose conditions (b). Effect of a P2X7R inhibitor (A438079) on MCP-1 secretion (c). Subtraction of normal glucose MCP-1 release highlighted the absolute magnitude of MCP-1 reduction by P2X7R blockade alone across 9 separate experiments (d). *P

    Article Snippet: Primary antibodies for P2X7R (APR-004, Alomone, RRID: AB_2040068 ; 1:50 murine; 1:100 human), human CD68 (Clone KP-1, Dako, RRID: AB_563621 ; 1:100), murine CD68 (Clone FA-11, Serotec, RRID: AB_323909 ; 1:200) and collagen IV (Ab6586, Abcam, RRID: AB_305584; 1:100) were reconstituted in PBS.

    Techniques: Activation Assay, Expressing

    Effect of P2X7R inhibitor on blood glucose levels and kidney function. Blood glucose measured at week 12 (a). Serum creatinine concentration in terminal serum (b) and albumin excretion rate (AER) (c). *P

    Journal: EBioMedicine

    Article Title: Hyperglycemia-induced Renal P2X7 Receptor Activation Enhances Diabetes-related Injury

    doi: 10.1016/j.ebiom.2017.04.011

    Figure Lengend Snippet: Effect of P2X7R inhibitor on blood glucose levels and kidney function. Blood glucose measured at week 12 (a). Serum creatinine concentration in terminal serum (b) and albumin excretion rate (AER) (c). *P

    Article Snippet: Primary antibodies for P2X7R (APR-004, Alomone, RRID: AB_2040068 ; 1:50 murine; 1:100 human), human CD68 (Clone KP-1, Dako, RRID: AB_563621 ; 1:100), murine CD68 (Clone FA-11, Serotec, RRID: AB_323909 ; 1:200) and collagen IV (Ab6586, Abcam, RRID: AB_305584; 1:100) were reconstituted in PBS.

    Techniques: Concentration Assay