phospho gsk 3α β ser21 9  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc phospho gsk 3α β ser21 9
    Phospho Gsk 3α β Ser21 9, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/phospho gsk 3α β ser21 9/product/Cell Signaling Technology Inc
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    rabbit anti phospho gsk 3β  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc rabbit anti phospho gsk 3β
    Rabbit Anti Phospho Gsk 3β, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    rabbit anti phospho gsk 3β  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc rabbit anti phospho gsk 3β
    Effect of RUR administration on the hyperphosphorylation of tau within DNs in the hippocampus. Representative photomicrographs of LAMP1 (green) and AT8 (red) immunopositive areas in the hippocampus are shown (n = 5 − 6 per group) ( A ). The percentage of colocalization (LAMP1:AT8) was measured using a colocalization finder from ImageJ ( B ). The representative band ( C ) and quantification of the AT8 normalized to total tau, <t>p-GSK-3β</t> (ser9) normalized to total GSK-3β, and p-Akt normalized to total Akt ( D ) are shown (n = 4 − 5 per group). The statistical analyses were performed using ANOVA, followed by Dunnett’s post hoc test. *** p < 0.001, ** p < 0.01 and * p < 0.05 vs. 5xFAD group. Scale bar = 200 μm
    Rabbit Anti Phospho Gsk 3β, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    1) Product Images from "Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-β induced neuritic dystrophy in 5xFAD mouse"

    Article Title: Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-β induced neuritic dystrophy in 5xFAD mouse

    Journal: Chinese Medicine

    doi: 10.1186/s13020-024-00966-2

    Effect of RUR administration on the hyperphosphorylation of tau within DNs in the hippocampus. Representative photomicrographs of LAMP1 (green) and AT8 (red) immunopositive areas in the hippocampus are shown (n = 5 − 6 per group) ( A ). The percentage of colocalization (LAMP1:AT8) was measured using a colocalization finder from ImageJ ( B ). The representative band ( C ) and quantification of the AT8 normalized to total tau, p-GSK-3β (ser9) normalized to total GSK-3β, and p-Akt normalized to total Akt ( D ) are shown (n = 4 − 5 per group). The statistical analyses were performed using ANOVA, followed by Dunnett’s post hoc test. *** p < 0.001, ** p < 0.01 and * p < 0.05 vs. 5xFAD group. Scale bar = 200 μm
    Figure Legend Snippet: Effect of RUR administration on the hyperphosphorylation of tau within DNs in the hippocampus. Representative photomicrographs of LAMP1 (green) and AT8 (red) immunopositive areas in the hippocampus are shown (n = 5 − 6 per group) ( A ). The percentage of colocalization (LAMP1:AT8) was measured using a colocalization finder from ImageJ ( B ). The representative band ( C ) and quantification of the AT8 normalized to total tau, p-GSK-3β (ser9) normalized to total GSK-3β, and p-Akt normalized to total Akt ( D ) are shown (n = 4 − 5 per group). The statistical analyses were performed using ANOVA, followed by Dunnett’s post hoc test. *** p < 0.001, ** p < 0.01 and * p < 0.05 vs. 5xFAD group. Scale bar = 200 μm

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    rabbit antiglycogen synthase kinase 3 gsk 3β antibody  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc rabbit antiglycogen synthase kinase 3 gsk 3β antibody
    Rabbit Antiglycogen Synthase Kinase 3 Gsk 3β Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    rabbit anti glycogen synthase kinase 3 gsk 3β antibody  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc rabbit anti glycogen synthase kinase 3 gsk 3β antibody
    Rabbit Anti Glycogen Synthase Kinase 3 Gsk 3β Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti glycogen synthase kinase 3 gsk 3β antibody/product/Cell Signaling Technology Inc
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    gsk 3β protein  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc gsk 3β protein
    Mice were fed chow or statin-containing diet with daily administration of either coconut oil vehicle or fish oil (as a source of ω-3 fatty acids) dissolved in coconut oil vehicle. After 5 weeks, a glucose tolerance and b grip strength were measured in female and male mice ( N = 5 mice/sex on each treatment). AUC, area under the curve for glucose tolerance test. Tissues from mice in a , b (5 mice/sex on each treatment) were used to determine c liver and muscle glycogen levels by biochemical assay, and d levels of total and phosphorylated glycogen synthase <t>kinase−3β</t> <t>(GSK−3β)</t> by immunoblot. The same blot was used sequentially for detection of phosphorylated and total GSK−3β and GAPDH. Values represent mean ± SEM. Data analyses were as in Fig. with p values representing pair-wise two-sided t-tests following significant 2-way ANOVA. Source data are provided as a Source Data file.
    Gsk 3β Protein, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Images

    1) Product Images from "X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction"

    Article Title: X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction

    Journal: Nature Communications

    doi: 10.1038/s41467-024-49764-2

    Mice were fed chow or statin-containing diet with daily administration of either coconut oil vehicle or fish oil (as a source of ω-3 fatty acids) dissolved in coconut oil vehicle. After 5 weeks, a glucose tolerance and b grip strength were measured in female and male mice ( N = 5 mice/sex on each treatment). AUC, area under the curve for glucose tolerance test. Tissues from mice in a , b (5 mice/sex on each treatment) were used to determine c liver and muscle glycogen levels by biochemical assay, and d levels of total and phosphorylated glycogen synthase kinase−3β (GSK−3β) by immunoblot. The same blot was used sequentially for detection of phosphorylated and total GSK−3β and GAPDH. Values represent mean ± SEM. Data analyses were as in Fig. with p values representing pair-wise two-sided t-tests following significant 2-way ANOVA. Source data are provided as a Source Data file.
    Figure Legend Snippet: Mice were fed chow or statin-containing diet with daily administration of either coconut oil vehicle or fish oil (as a source of ω-3 fatty acids) dissolved in coconut oil vehicle. After 5 weeks, a glucose tolerance and b grip strength were measured in female and male mice ( N = 5 mice/sex on each treatment). AUC, area under the curve for glucose tolerance test. Tissues from mice in a , b (5 mice/sex on each treatment) were used to determine c liver and muscle glycogen levels by biochemical assay, and d levels of total and phosphorylated glycogen synthase kinase−3β (GSK−3β) by immunoblot. The same blot was used sequentially for detection of phosphorylated and total GSK−3β and GAPDH. Values represent mean ± SEM. Data analyses were as in Fig. with p values representing pair-wise two-sided t-tests following significant 2-way ANOVA. Source data are provided as a Source Data file.

    Techniques Used: Western Blot

    phospho gsk 3β ser9  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc phospho gsk 3β ser9
    Mice were fed chow or statin-containing diet with daily administration of either coconut oil vehicle or fish oil (as a source of ω-3 fatty acids) dissolved in coconut oil vehicle. After 5 weeks, a glucose tolerance and b grip strength were measured in female and male mice ( N = 5 mice/sex on each treatment). AUC, area under the curve for glucose tolerance test. Tissues from mice in a , b (5 mice/sex on each treatment) were used to determine c liver and muscle glycogen levels by biochemical assay, and d levels of total and phosphorylated glycogen synthase <t>kinase−3β</t> <t>(GSK−3β)</t> by immunoblot. The same blot was used sequentially for detection of phosphorylated and total GSK−3β and GAPDH. Values represent mean ± SEM. Data analyses were as in Fig. with p values representing pair-wise two-sided t-tests following significant 2-way ANOVA. Source data are provided as a Source Data file.
    Phospho Gsk 3β Ser9, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    1) Product Images from "X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction"

    Article Title: X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction

    Journal: Nature Communications

    doi: 10.1038/s41467-024-49764-2

    Mice were fed chow or statin-containing diet with daily administration of either coconut oil vehicle or fish oil (as a source of ω-3 fatty acids) dissolved in coconut oil vehicle. After 5 weeks, a glucose tolerance and b grip strength were measured in female and male mice ( N = 5 mice/sex on each treatment). AUC, area under the curve for glucose tolerance test. Tissues from mice in a , b (5 mice/sex on each treatment) were used to determine c liver and muscle glycogen levels by biochemical assay, and d levels of total and phosphorylated glycogen synthase kinase−3β (GSK−3β) by immunoblot. The same blot was used sequentially for detection of phosphorylated and total GSK−3β and GAPDH. Values represent mean ± SEM. Data analyses were as in Fig. with p values representing pair-wise two-sided t-tests following significant 2-way ANOVA. Source data are provided as a Source Data file.
    Figure Legend Snippet: Mice were fed chow or statin-containing diet with daily administration of either coconut oil vehicle or fish oil (as a source of ω-3 fatty acids) dissolved in coconut oil vehicle. After 5 weeks, a glucose tolerance and b grip strength were measured in female and male mice ( N = 5 mice/sex on each treatment). AUC, area under the curve for glucose tolerance test. Tissues from mice in a , b (5 mice/sex on each treatment) were used to determine c liver and muscle glycogen levels by biochemical assay, and d levels of total and phosphorylated glycogen synthase kinase−3β (GSK−3β) by immunoblot. The same blot was used sequentially for detection of phosphorylated and total GSK−3β and GAPDH. Values represent mean ± SEM. Data analyses were as in Fig. with p values representing pair-wise two-sided t-tests following significant 2-way ANOVA. Source data are provided as a Source Data file.

    Techniques Used: Western Blot

    gsk 3β 3d10  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc gsk 3β 3d10
    Gsk 3β 3d10, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    phospho gsk 3β ser9 5b3  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc phospho gsk 3β ser9 5b3
    Phospho Gsk 3β Ser9 5b3, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    phospho gsk 3β ser9  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc phospho gsk 3β ser9
    Phospho Gsk 3β Ser9, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Cell Signaling Technology Inc phospho gsk 3α β ser21 9
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    Cell Signaling Technology Inc gsk 3β protein
    Mice were fed chow or statin-containing diet with daily administration of either coconut oil vehicle or fish oil (as a source of ω-3 fatty acids) dissolved in coconut oil vehicle. After 5 weeks, a glucose tolerance and b grip strength were measured in female and male mice ( N = 5 mice/sex on each treatment). AUC, area under the curve for glucose tolerance test. Tissues from mice in a , b (5 mice/sex on each treatment) were used to determine c liver and muscle glycogen levels by biochemical assay, and d levels of total and phosphorylated glycogen synthase <t>kinase−3β</t> <t>(GSK−3β)</t> by immunoblot. The same blot was used sequentially for detection of phosphorylated and total GSK−3β and GAPDH. Values represent mean ± SEM. Data analyses were as in Fig. with p values representing pair-wise two-sided t-tests following significant 2-way ANOVA. Source data are provided as a Source Data file.
    Gsk 3β Protein, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Cell Signaling Technology Inc phospho gsk 3β ser9
    Mice were fed chow or statin-containing diet with daily administration of either coconut oil vehicle or fish oil (as a source of ω-3 fatty acids) dissolved in coconut oil vehicle. After 5 weeks, a glucose tolerance and b grip strength were measured in female and male mice ( N = 5 mice/sex on each treatment). AUC, area under the curve for glucose tolerance test. Tissues from mice in a , b (5 mice/sex on each treatment) were used to determine c liver and muscle glycogen levels by biochemical assay, and d levels of total and phosphorylated glycogen synthase <t>kinase−3β</t> <t>(GSK−3β)</t> by immunoblot. The same blot was used sequentially for detection of phosphorylated and total GSK−3β and GAPDH. Values represent mean ± SEM. Data analyses were as in Fig. with p values representing pair-wise two-sided t-tests following significant 2-way ANOVA. Source data are provided as a Source Data file.
    Phospho Gsk 3β Ser9, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Cell Signaling Technology Inc gsk 3β 3d10
    Mice were fed chow or statin-containing diet with daily administration of either coconut oil vehicle or fish oil (as a source of ω-3 fatty acids) dissolved in coconut oil vehicle. After 5 weeks, a glucose tolerance and b grip strength were measured in female and male mice ( N = 5 mice/sex on each treatment). AUC, area under the curve for glucose tolerance test. Tissues from mice in a , b (5 mice/sex on each treatment) were used to determine c liver and muscle glycogen levels by biochemical assay, and d levels of total and phosphorylated glycogen synthase <t>kinase−3β</t> <t>(GSK−3β)</t> by immunoblot. The same blot was used sequentially for detection of phosphorylated and total GSK−3β and GAPDH. Values represent mean ± SEM. Data analyses were as in Fig. with p values representing pair-wise two-sided t-tests following significant 2-way ANOVA. Source data are provided as a Source Data file.
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    Cell Signaling Technology Inc phospho gsk 3β ser9 5b3
    Mice were fed chow or statin-containing diet with daily administration of either coconut oil vehicle or fish oil (as a source of ω-3 fatty acids) dissolved in coconut oil vehicle. After 5 weeks, a glucose tolerance and b grip strength were measured in female and male mice ( N = 5 mice/sex on each treatment). AUC, area under the curve for glucose tolerance test. Tissues from mice in a , b (5 mice/sex on each treatment) were used to determine c liver and muscle glycogen levels by biochemical assay, and d levels of total and phosphorylated glycogen synthase <t>kinase−3β</t> <t>(GSK−3β)</t> by immunoblot. The same blot was used sequentially for detection of phosphorylated and total GSK−3β and GAPDH. Values represent mean ± SEM. Data analyses were as in Fig. with p values representing pair-wise two-sided t-tests following significant 2-way ANOVA. Source data are provided as a Source Data file.
    Phospho Gsk 3β Ser9 5b3, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Mice were fed chow or statin-containing diet with daily administration of either coconut oil vehicle or fish oil (as a source of ω-3 fatty acids) dissolved in coconut oil vehicle. After 5 weeks, a glucose tolerance and b grip strength were measured in female and male mice ( N = 5 mice/sex on each treatment). AUC, area under the curve for glucose tolerance test. Tissues from mice in a , b (5 mice/sex on each treatment) were used to determine c liver and muscle glycogen levels by biochemical assay, and d levels of total and phosphorylated glycogen synthase kinase−3β (GSK−3β) by immunoblot. The same blot was used sequentially for detection of phosphorylated and total GSK−3β and GAPDH. Values represent mean ± SEM. Data analyses were as in Fig. with p values representing pair-wise two-sided t-tests following significant 2-way ANOVA. Source data are provided as a Source Data file.

    Journal: Nature Communications

    Article Title: X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction

    doi: 10.1038/s41467-024-49764-2

    Figure Lengend Snippet: Mice were fed chow or statin-containing diet with daily administration of either coconut oil vehicle or fish oil (as a source of ω-3 fatty acids) dissolved in coconut oil vehicle. After 5 weeks, a glucose tolerance and b grip strength were measured in female and male mice ( N = 5 mice/sex on each treatment). AUC, area under the curve for glucose tolerance test. Tissues from mice in a , b (5 mice/sex on each treatment) were used to determine c liver and muscle glycogen levels by biochemical assay, and d levels of total and phosphorylated glycogen synthase kinase−3β (GSK−3β) by immunoblot. The same blot was used sequentially for detection of phosphorylated and total GSK−3β and GAPDH. Values represent mean ± SEM. Data analyses were as in Fig. with p values representing pair-wise two-sided t-tests following significant 2-way ANOVA. Source data are provided as a Source Data file.

    Article Snippet: Total and phosphorylated glycogen synthase kinase (GSK) 3β protein levels were determined by immunoblot using antibodies (1:1000 dilution) that recognize phospho-GSK-3β Ser9 (Cell Signaling Technology rabbit polyclonal antibody #9336, lot 14) or total GSK-3β protein (Cell Signaling Technology monoclonal antibody #9315, clone 27C10).

    Techniques: Western Blot

    Mice were fed chow or statin-containing diet with daily administration of either coconut oil vehicle or fish oil (as a source of ω-3 fatty acids) dissolved in coconut oil vehicle. After 5 weeks, a glucose tolerance and b grip strength were measured in female and male mice ( N = 5 mice/sex on each treatment). AUC, area under the curve for glucose tolerance test. Tissues from mice in a , b (5 mice/sex on each treatment) were used to determine c liver and muscle glycogen levels by biochemical assay, and d levels of total and phosphorylated glycogen synthase kinase−3β (GSK−3β) by immunoblot. The same blot was used sequentially for detection of phosphorylated and total GSK−3β and GAPDH. Values represent mean ± SEM. Data analyses were as in Fig. with p values representing pair-wise two-sided t-tests following significant 2-way ANOVA. Source data are provided as a Source Data file.

    Journal: Nature Communications

    Article Title: X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction

    doi: 10.1038/s41467-024-49764-2

    Figure Lengend Snippet: Mice were fed chow or statin-containing diet with daily administration of either coconut oil vehicle or fish oil (as a source of ω-3 fatty acids) dissolved in coconut oil vehicle. After 5 weeks, a glucose tolerance and b grip strength were measured in female and male mice ( N = 5 mice/sex on each treatment). AUC, area under the curve for glucose tolerance test. Tissues from mice in a , b (5 mice/sex on each treatment) were used to determine c liver and muscle glycogen levels by biochemical assay, and d levels of total and phosphorylated glycogen synthase kinase−3β (GSK−3β) by immunoblot. The same blot was used sequentially for detection of phosphorylated and total GSK−3β and GAPDH. Values represent mean ± SEM. Data analyses were as in Fig. with p values representing pair-wise two-sided t-tests following significant 2-way ANOVA. Source data are provided as a Source Data file.

    Article Snippet: Total and phosphorylated glycogen synthase kinase (GSK) 3β protein levels were determined by immunoblot using antibodies (1:1000 dilution) that recognize phospho-GSK-3β Ser9 (Cell Signaling Technology rabbit polyclonal antibody #9336, lot 14) or total GSK-3β protein (Cell Signaling Technology monoclonal antibody #9315, clone 27C10).

    Techniques: Western Blot