Anti Cav 2 1, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti cav 2 1/product/Alomone Labs
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
1) Product Images from "Dendritic and axonal mechanisms of Ca2+ elevation impair BDNF transport in Aβ oligomer–treated hippocampal neurons"
Article Title: Dendritic and axonal mechanisms of Ca2+ elevation impair BDNF transport in Aβ oligomer–treated hippocampal neurons
Journal: Molecular Biology of the Cell
Figure Legend Snippet: AβOs bind to axons and colocalize with presynaptic voltage-gated calcium channels. (A) Representative images of immunocytochemistry with an AβO-specific antibody (NU-4) show that AβOs bind along the entire length of the axon in cultured neurons. (B) Immunohistochemistry on coronal sections from 12-mo-old transgenic AD mouse brain (LaFerla 3xTg) reveal a punctate distribution of AβOs along axons in the cortex. Axons are distinguished by the absence of MAP2 staining (inset). AβOs were not detected in age-matched wild-type control mice. (C) Representative images of AβO and CaV 2.1 (P/Q-type VGCC) immunocytochemistry. Of axonal AβOs, 83.5% colocalize with P/Q-type VGCCs. A minimum of 15 cells from three independent cultures were analyzed. Arrows indicate axons, arrowheads indicate dendrites, and asterisks indicate regions of overlapping puncta. Scale bar, 100 μm.
Techniques Used: Immunocytochemistry, Cell Culture, Immunohistochemistry, Transgenic Assay, Staining, Mouse Assay