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anti c5b 9 mac mouse monoclonal antibody  (Agilent technologies)


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    Agilent technologies anti c5b 9 mac mouse monoclonal antibody
    Anti C5b 9 Mac Mouse Monoclonal Antibody, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti c5b 9 mac mouse monoclonal antibody/product/Agilent technologies
    Average 86 stars, based on 1 article reviews
    anti c5b 9 mac mouse monoclonal antibody - by Bioz Stars, 2025-07
    86/100 stars

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    anti c5b 9 mac mouse monoclonal antibody  (Agilent technologies)
    86
    Agilent technologies anti c5b 9 mac mouse monoclonal antibody
    Anti C5b 9 Mac Mouse Monoclonal Antibody, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti c5b 9 mac mouse monoclonal antibody/product/Agilent technologies
    Average 86 stars, based on 1 article reviews
    anti c5b 9 mac mouse monoclonal antibody - by Bioz Stars, 2025-07
    86/100 stars
    		  Buy from Supplier
    monoclonal mouse anti mac c5b 9  (Agilent technologies)
    86
    Agilent technologies monoclonal mouse anti mac c5b 9
    Deposition of IgG and C1q and complement activation are observed in the choriocapillaris of patients with early AMD. (a) Immunohistochemical detection of IgG (green) and U. europaeus agglutinin I (red) (n = 9–11 per group) revealed IgG deposition in close proximity to choriocapillaris in both control and early AMD eyes. (b) Immunohistochemical detection of IgG (green) and C1q (red) (n = 9 per group) in aged-matched controls and patients with early AMD showed colocalization of IgG and C1q (arrows) in blood vessel lumens, indicating formation of immune complexes but not in drusen (star) (c) Immunohistochemical detection of IgG (green) and MAC <t>(C5b-9,</t> red) in aged-matched controls and patients with early AMD (n = 9 per group) revealed MAC and IgG colocalization around the choriocapillaris (arrowheads) and in drusen (star) in early AMD (inset). Note the intense autofluorescence of the RPE due to lipofuscin autofluorescence. CC, choriocapillaris. Scale bars: 50 μm and 25 μm (inset).
    Monoclonal Mouse Anti Mac C5b 9, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/monoclonal mouse anti mac c5b 9/product/Agilent technologies
    Average 86 stars, based on 1 article reviews
    monoclonal mouse anti mac c5b 9 - by Bioz Stars, 2025-07
    86/100 stars
    		  Buy from Supplier

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    Deposition of IgG and C1q and complement activation are observed in the choriocapillaris of patients with early AMD. (a) Immunohistochemical detection of IgG (green) and U. europaeus agglutinin I (red) (n = 9–11 per group) revealed IgG deposition in close proximity to choriocapillaris in both control and early AMD eyes. (b) Immunohistochemical detection of IgG (green) and C1q (red) (n = 9 per group) in aged-matched controls and patients with early AMD showed colocalization of IgG and C1q (arrows) in blood vessel lumens, indicating formation of immune complexes but not in drusen (star) (c) Immunohistochemical detection of IgG (green) and MAC (C5b-9, red) in aged-matched controls and patients with early AMD (n = 9 per group) revealed MAC and IgG colocalization around the choriocapillaris (arrowheads) and in drusen (star) in early AMD (inset). Note the intense autofluorescence of the RPE due to lipofuscin autofluorescence. CC, choriocapillaris. Scale bars: 50 μm and 25 μm (inset).

    Journal: Investigative Ophthalmology & Visual Science

    Article Title: Fc? Receptor Upregulation Is Associated With Immune Complex Inflammation in the Mouse Retina and Early Age-Related Macular Degeneration

    doi: 10.1167/iovs.13-11821

    Figure Lengend Snippet: Deposition of IgG and C1q and complement activation are observed in the choriocapillaris of patients with early AMD. (a) Immunohistochemical detection of IgG (green) and U. europaeus agglutinin I (red) (n = 9–11 per group) revealed IgG deposition in close proximity to choriocapillaris in both control and early AMD eyes. (b) Immunohistochemical detection of IgG (green) and C1q (red) (n = 9 per group) in aged-matched controls and patients with early AMD showed colocalization of IgG and C1q (arrows) in blood vessel lumens, indicating formation of immune complexes but not in drusen (star) (c) Immunohistochemical detection of IgG (green) and MAC (C5b-9, red) in aged-matched controls and patients with early AMD (n = 9 per group) revealed MAC and IgG colocalization around the choriocapillaris (arrowheads) and in drusen (star) in early AMD (inset). Note the intense autofluorescence of the RPE due to lipofuscin autofluorescence. CC, choriocapillaris. Scale bars: 50 μm and 25 μm (inset).

    Article Snippet: The primary antibodies used were the following: FITC-labeled donkey F(ab′) 2 fragment anti-human IgG (Jackson ImmunoResearch Laboratories), polyclonal rabbit anti-C1q (Dako, Cambridge, UK), monoclonal mouse anti-MAC-C5b-9 (aE11; Dako), monoclonal mouse anti-human CD45 (HI30; BD Biosciences, Oxford, UK), monoclonal rabbit anti-FcγRIIb (EP888Y; Abcam), monoclonal rabbit anti-FcγRIIa (EPR6658; Epitomics–an Abcam Company, Burlingame, CA), monoclonal mouse anti-FcγRIII (2h7; Abcam), polyclonal goat anti-FcγRI (R&D Systems), and biotinylated Ullex europaeus agglutinin I (UEA1; Vector Laboratories).

    Techniques: Activation Assay, Immunohistochemical staining